#NEXUS
[Computer generated Nexus file using Nexus package designed
by Weigang Qiu, Eugene Melamud and Peter Yang; from the original
kindly provided by Mario Fares (Fares & Wolfe, Mol Biol Evol. 2003 Oct; 20(10): 1588-97)]
begin taxa;
dimensions ntax=59;
taxlabels Hs_theta Mm_theta Ce_tetha At_theta Sc_theta Hs_gamma Mm_gamma Ce_gamma Sc_gamma At_gamma Mm_beta Mm_alfa Hs_alfa Ce_alfa At_alfa Sc_alfa Gi_alfa Tv_alfa Hs_beta At_beta Sc_beta Ce_beta Gi_bet Hs_etha Mm_etha At_etha Ce_etha Sc_etha Tv_etha Hs_delta Mm_delta At_delta Ce_delta Sc_delta Tv_delta Mm_epsilon Hs_epsilon At_epsilon Ce_epsilon Sc_epsilon Gi_epsilon sulfolobus Aeropyruma Methanococ Pyrococcusalf Archaeoglobus thermoplasm Aeropytrum2 Sulfolobus_beta Haloferax Hs_zeta1 Hs_zeta2 Mm_zetaA Mm_zetaB Ce_zeta At_zeta Tv_zeta Sc_zeta Gi_zeta;
end;
begin characters;
dimensions ntax=59 nchar=687;
format datatype=protein gap=- missing=-;
matrix
Aeropyruma -------------MVEMAATGYPVLILKEGTQRTYGREALRANILAARVLAEMLKSSLGPRGLDKMLVDAFGD----ITVTNDGATIVKEM-----EIQHPAAKLLVEVAKAQDAEVGDGTTSVVVLAGALLEKAEKLLDE-NLHPTIIIEGYTKAMEEALR-LVDEAAVPVEVEDD------SVLRRIAETTLASKFVGTGPERDKIISMVIDAIRTVAE------KRPDGGYEVDLDYVKIEKKKGGSLLDSKLVRGIVLDKEVVHPAMPKRVEN------AKILVLDAPLEVQKPELTTKIRVTDIEKLESFLEEETRMLRDMVEKIAA---------------------------------TGANVVITQKG-----IDEVAQHFLAKKGILAVRRVKRSDIEKVAKATGAKIVTSLRDLK------PEYLGYAELVEERKVGEDKMVFIEGAK-----------NPKSV-----TILLRGANDMLLDEAERNIKDALHGLRNILR--EPKIVGGGGAVEVELALKLK---EFARTVGGKQQLAIEAYAEALETIPTVLAESAGMDALEALLKLRSLHSQ-GYK-----------FAGVNVLEGK--IEEDMTKINVYEPVLVKKQVIKSASEAAISILKIDDVIAAAPPKKKEKKGKTGEEEEEEGGGSKFEF---------
Aeropytrum2 -MVDRVIEMAIQQQPMTEPVGIPVIILKEGTQRSYGREALRANIMAVRAIAQILKTTYGPKGMDKMLVDSLGD----ITITNNGATILDKM-----DVAHPAAKMLVQISKGQEDEAGDGTKTTVIFAGELLKEAEKLLDI-NIHPTIIVEGYKEALRKASE-VIESIAEPVSYDDV------EKLKLIAKTSLNSK--AVAEARDYFAELAVEAVRTVAE------RR-GDRWYVDLNNIQIVKKHGGSLRDTRLVRGIVLDKEVVHPDMPRRVEN------ARIALLDTPLEIEKPEIDLEISITSPEQIKALYEKQERILQEKIEKIAA---------------------------------TGANVVITQKG-----IDDVAQHFLAKKGILAVRRVKRSDIEKIARATGARIVTDIEDLR------PEDLGYAELVEERKVGEDKMVFIEGAK-----------NPKSV-----TILLRGGFERLVDEAERSLHDALSVVADAIM--DGKIVAGGGAVEAEVAKVLY---EYASKLPGKTQLAVEAFARAVEALPQALAHNAGHDPIEVLVKLRSAHEKPENK-----------WYGVDLDTGE--IVD-MWSRGVLEPMRVKLNALKAATEVASLILRIDDVIAARKEEEEKEEKRGGEEE--------------------
Archaeoglobus ---------------MATLQGQPVLILREGTQRTVGRDAQRMNIMAARVIAEAVRSTLGPKGMDKMLVDSLGD----VVITNDGVTILKEI-----DVEHPAAKMIIEVAKTQDNEVGDGTTTAVVLAGELLKRAEELLDQ-EIHPAIIANGYRYAAEKALE-ILNEIAIPISKDDD------EILKKIATTAMTGK--GAEVAIDKLAEIAVNAVKMIAE------ES-NGQVEVNTDYIKIEKRQGGSIEETELVDGIVLDKEVVHPGMPKRVEN------AKILLLDSALEVKETEIDAKIRITDPEKLQKFIEQEEAMLKEMVDKIVN---------------------------------AGANVVFCQKG-----IDDLAQYYLAKAGVLAVRRVKKSDMEKLAKATGAKVLTDLRDIS------SEDLGEAALVEERKVGDEKMVFVTGCK-----------NPKAV-----TILVRGGTEHVVEEIARGIEDAVRAVACAVE--DGKVVVGAGAPEIEVSLKLR---EWAPSLGGREQLAVEAFATALEIIPRTLAENAGLDPIDVLVELKAAHEK-GQK-----------YAGVDVDTGK--VVD-MKERGVFEPLRVKTQAIGSATEVAVMILRIDDIIAAKGLEKEKGGGG--EGGMPEMPEF-------------
At_alfa -------------------MSISAQNPDISGDRQSGQDVRTQNVMACQAVSNIVKTSLGPVGLDKMLVDDIG----DVTITNDGATILRML-----EVEHPAAKVLVELAELQDREVGDGTTSVVIVAAELLKRANDLVRN-KIHPTSIISGYRLAMRESCK-YIEEKLVTKVEKLG----KVPLIN-CAKTSMSSK--LISGDSDFFANLVVEAVLSVKM------TNQRGEIKYPIKGINILKAHGQSARDSYLLNG-YALNTGRAAQGMPLRVS-----PAKIACLDFNLQKTKMQLGVQVVVNDPRELEKIRQREADMTKERIEKLLK---------------------------------AGANVILTTKG-----IDDMALKYFVEAGAIAVRRVRKEDMRHVAKATGATLVTTFADMEGEETFDPAHLGSADEVVEERIADDDVILIKGTK-----------TSSAV-----SLILRGANDYMLDEMERALHDALCIVKRTLE--SNTVVAGGGAVESALSVYLE---HLATTLGSREQLAIAEFADALLIIPKVLAVNAAKDATELVAKLRAYHHTAQTK-AD---KKHYSSMGLDLVNGT--IRN-NLEAGVIEPAMSKVKIIQFATEAAITILRIDDMIKLVKD---------------------------------
At_beta --------------------MPIDKIFKDDASEEKGERARMASFVGAMAISDLVKSTLGPKGMDKILQSTGR--GHAVTVTNDGATILKSL-----HIDNPAAKVLVDISKVQDDEVGDGTTSVVVLAGELLREAEKLVAS-KIHPMTIIAGYRMASECARN-ALLKRVIDNKDNAEK--FRSDLLK-IAMTTLCSK--ILSQDKEHFAEMAVDAVFRLKG------STN-------LEAIQIIKKPGGSLKDSFLDEG--FILDKKIGIGQPKRIENA---NILVANTAMDTDK-VKIYGARVRVDSMTKVAEIEGAEKEKMKDKVKKIIG---------------------------------HGINCFVNRQL-----IYNFPEELFADAGILAIEHADFEGIERLGLVTGGEIASTFDNPE------SVKLGHCKLIEEIMIGEDKLIHFSGCE-----------MGQAC-----SIVLRGASHHVLDEAERSLHDALCVLSQTVN--DTRVLLGGGWPEMVMAKEVD---ELARKTAGKKSHAIEAFSRALVAIPTTIADNAGLDSAELVAQLRAEHHTEGCN------------AGIDVITGA--VGD-MEERGIYEAFKVKQAVLLSATEASEMILRVDEIITCA-----------------------------------
At_delta ----------MAAVAAPMASKPRGSKAESFVDNKRREDIRFANINSARAVSDAVRTSLGPKGMDKMISTANGE----VIITNDGATILNKM-----EVLQPAAKMLVELSKSQDSAAGDGTTTVVVIAGALLKECQSLLTN-GIHPTVISDSLHKACGKAID-ILTAMAVPVELT------DRDSLVKSASTSLNSK--VVSQYSTLLAPLAVDAVLSVID------PEKPEIVD--LRDIKIVKKLGGTVDDTHTVKGLVFDKKVSRAAGGPTRVEN-----AKIAVIQFQISPPKTDIEQSIVVSDYTQMDRILKEERNYILGMIKKIKA---------------------------------TGCNVLLIQKSILRDAVTDLSLHYLAKAKIMVIKDVERDEIEFVTKTLNCLPIANIEHFR------AEKLGHADLVEEASL-GDGKILKITG-------IKD--MGRTT-----SVLVRGSNQLVLDEAERSLHDALCVVRCLVS--KRFLIAGGGAPEIELSRQLG---AWAKVLHGMEGYCVKSFAEALEVIPYTLAENAGLNPIAIVTELRNKHAQ-GEI-----------NAGINVRKGQ--ITN-ILEENVVQPLLVSTSAITLATECVRMILKIDDIVTVR-----------------------------------
At_epsilon ------MA----LAFDEFGRPFIILREQDQKTRLRGIDAQKANIAAGKAVARILRSSLGPKGMDKMLQGPDGD----ITITNDGATILEQM-----DVDNQIAKLMVELSRSQDYEIGDGTTGVVVMAGALLEQAERQLDR-GIHPIRIAEGYEMASRVAVE-HLERIAQKFEFDVN----NYEPLVQTCMTTLSSK--IVNRCKRSLAEIAVKAVLAVAD-------LERRDVN--LDLIKVEGKVGGKLEDTELIYGILIDKDMSHPQMPKQIED------AHIAILTCPFEPPKPKTKHKVDIDTVEKFETLRKQEQQYFDEMVQKCKD---------------------------------VGATLVICQWG-----FDDEANHLLMHRNLPAVRWVGGVELELIAIATGGRIVPRFQELT------PEKLGKAGVVREKSFGTTKERMLYIE---------HCANSKAV-----TVFIRGGNKMMIEETKRSIHDALCVARNLIR--NKSIVYGGGAAEIACSLAVD---AAADKYPGVEQYAIRAFAEALDSVPMALAENSGLQPIETLSAVKSQQIKENIP-----------FYGIDCNDVG--TND-MREQNVFETLIGKQQQILLATQVVKMILKIDDVISNSEY---------------------------------
At_etha ---------------MASMMQPQIILLKEGTDTSQGKAQLVSNINACTAVGDVVRTTLGPRGMDKLIHDDKGS----VTISNDGATIMKLL-----DIVHPAAKILVDIAKSQDSEVGDGTTTVVLLAAEFLKEAKPFIED-GVHAQNLIRSYRTASTLAIA-KVKELAVSIEGKSVE--EKKGLLAKCAATTLSSK--LIGGEKEFFATMVVDAVMAIG-------NDDR------LNLIGIKKVPGGNMRDSFLVDGVAFKKTFSYAGFEQQPKKFL---NPKILLLNIELELKSEKENAEIRLSDPSQYQSIVDAEWNIIYDKLDKCVE---------------------------------SGAKVVLSRLA-----IGDLATQYFADRDIFCAGRVAEEDLNRVAAAAGGTVQTSVNNII------DEVLGTCEIFEEKQVGGERFNIFSGCP-----------SGRTA-----TIVLRGGADQFIEEAERSLHDAIMIVRRAVK--NSTVVPGGGAIDMEISKYLR---QHSRTIAGKSQLFINSYAKALEVIPRQLCDNAGFDATDVLNKLRQKHAMQSGE---------GASYGVDINTGG--IAD-SFANFVWEPAVVKINAINAATEAACLILSVDETVKNP-----------------------------------
At_gamma -------------------MQAPVVFMNASQERTTGRQAQISNITAAKAVADVIRTCLGPKAMLKMLLDPMGG----LVLTNDGHAILREI-----DVAHPAAKSMLELSRTQDEEVGDGTTTVIILAGEILAQCAPYLIEKNIHPVIIIQALKKALTDALE-VIKQVSKPVDVEND------AAMKKLIQASIGTK--YVIHWSEKMCELALDAVKTVRKDLGQTVEGEPNFEIDIKRYVRVEKIPGGDVLDSRVLKGVLLNKDVVHPKMSRHIEN------PRVVLLDCPLEYKKGESQTNIEIEKEEDWNRILQIEEEQVQLMCEQILA---------------------------------VRPTLVITEKG-----VSDLAQHYLLKGGCSVLRRVKKSDNNRIARVTGATIVNRVEDLK-----ESDVGTNCGLFKVEMIGDEYFSFLDNCK-----------EPKAC-----TIMLRGGSKDILNEIDRNLQDAMAVARNVML--SPSLSPGGGATEMAVSVKLA---EKAKQLEGIQQWPYQAVADAMECIPRTLIQNAGGDPIRLLSQLRAKHAQ--GNFTT----------GIDGDKGK--IVD-MVSYGIWEPEVIKQQSVKTAIESACLLLRVDDIVSGVRKQE-------------------------------
At_theta -----------MVGMSMQPYGIQSMLKEGYRHLSGLDEAVIKNIEACKELSTITRTSLGPNGMNKMVINHLDK----LFVTNDAATIVNEL-----EIQHPAAKLLVLAAKAQQEEIGDGANLTISFAGELLQNAEELIRM-GLHPSEIISGYTKAVSKAVEILEQLVETGSETMDVR---NKDEVISRMRAAVASK---QFGQEEIICSLVTDACIQVCPKN---------PTNFNVDNVRVSKLLGGGLHNSCIVRGMVLKSDAVGSIKRMEKAK--------VAVFAGGVDTTATETKGTVLIHSAEQLENYAKTEEAKVEELIKAVAE---------------------------------SGAKVIVSGGS-----IGEMALHFCERYKIMVLKISSKFELRRFCRTAGAVAHLKLSRPS------PEDLGYVDSISVEEIGGVTVTIARNE----------EGGNSIS-----TVVLRGSTDSILDDLERAVDDGVNTYKAMCR--DSRIVPGAAATEIELAQRLK---EYANAEIGLDKYAITKYAESFEFVPKTLADNAGLNAMEIIAALYTGHGSGNT------------KLGIDLEEG---ACKDVSETKVWDLFATKLFALKYASDAACTVLRVDQVCTN------------------------------------
At_zeta ---------------------MSVRVLNPNAEVLNKSAALHMTINAAKGLQDVLKSNLGPKGTIKMLVGGSGD----IKLTKDGNTLLKEMGAQKPQIQNPTAIMIARTAVAQDDISGDGTTSTVIFIGELMKQSERCIDE-GMHPRVLVDGFEIAKRATLQ-FLDNFKTPVVMGDEV---DKEILKMVARTTLRTK--LYEGLADQLTDIVVNSVLCIRKP-----EEA-----IDLFMVEIMHMRHKFDVDTRLVEGLVLDHGSRHPDMKRR-AENCH-----ILTCNVSLEYEKSEINAGFFYSNAEQREAMVTAERRSVDERVKKIIELKKKVCGDN-------------------------DNFVVINQKG-----IDPPSLDLLAREGIIGLRRAKRRNMERLVLACGGEAVNSVDDLT------PESLGWAGLVYEHVLGEEKYTFVEQVK-----------NPNSC-----TILIKGPNDHTIAQIKDAVRDGLRSVKNTIE--DECVVLGAGAFEVAARQHLLN--EVKKTVQGRAQLGVEAFANALLVVPKTLAENAGLDTQDVIISLTSEHDK-------------GNVVGLNLQDGE---PIDPQLAGIFDNYSVKRQLINSGPVIASQLLLVDEVIRAGRNMRKPTA---------------------------
Ce_alfa -------------------------MLTLGGERTSGESVRKQNVLAACSFANFVKTSLGPVGLDKMLVDDVG----DVTITNDGATILKLL-----DVEHPAAKILVQLAQLQDEEVGDGTTSVVILAAALLKNADELISR-FVHPTTVINGYRLACREACK-YIQEHMAYDVNKLG----KAGLIN-VARTAMSSK--LINLDADMFSQMAVDALMAVEV------SGGPKGPVYPIKAVNILKAHGRSMSESMLIDG-YALNCTAASQQMPRIIK-----KAKIAFLDFSLQKVKMKLGVQVVVKDPAQLEAIRQREADITKERIQKILN---------------------------------AGANVILTTGG-----IDDLCMKYFVEVNAMAVRRCKKVDLKNMAKATGGQLIVSLADMEGDEVFDPTKLGNAEEVSQERICDDELIILRGPK-----------VHPSA-----SIILRGANDFYVDEMERSLHDALLVVKRVLE--SKRIVPGAGACETAVSIYLE---NYALTLSSREQLAIAEFARAMLSIPKQLAVNAGVDSTELVARLRSCHNSSQSK-PD---QAHNKWWGLDLNNQY--VAD-CKEIGVFEPLVSKIKSLKFATEAAITILRIDDLIKLK-----------------------------------
Ce_beta --------------------MLPVQILKDNAQEERGESARLSSFVGAIAIGDLVKSTLGPKGMDKILISGNPESAGGIKVTNDGATILKSI-----GVDNPAAKVLVDMSMTQDHEVGDGTTSVTVLAAELLKEAEKLVNQ-RIHPQTIISGYRRALGIAQE-SLKKSSIESGDN-----IRDDLLK-IARTTLGSK--ILSQHKEHFAQLAVDAVLRLKG------SGN-------LDAIQIIKKLGGSMNESYLDEG--FLLEKLPGMFQPRRVEKA---KILIANTPMDTDK-VKVFGSRVRVDGVAKVAELEAAEKLKMKEKVDKILA---------------------------------HNCNVFINRQL-----IYNYPEQLFADAKVMAIEHADFEGIERLALVLGGEIVSTFDSPQ------TAQFGSCDLIEEIMIGEDRLLRFSGVK-----------LGEAC-----SVVLRGATQQILDESERSLHDALCVLVTHVK--ESKTVAGAGASEILMSSAIA---VEAQKVAGKESLAVEAFGRALAQLPTIICDNAGLDSAELVTRLRAEHANGRHN------------MGIDIEKGE--VAD-VTKLGVIESYNVKLCMVSSAAEATEQILRVDDIIKAA-----------------------------------
Ce_delta ------MPP-AVPAAAATARQSASGRERNFKDKDKPESVRNSNIVAAKAVADAVRTSLGPRGMDKMIQSGNGD----VTITNDGATILNQM-----SVIHPTAKMLVELSKAQDIEAGDGTTTVVVMAGALLDAAQNLLSK-GIHPTTISESFQSAAAEAEK-ILDEMSSPVDLS------NDALLNKMATTSLNSK--VVSQHSWLLAPMAVNAVKKIIN------SENDSNVN--LKMIKIIKKMGDTVEESELIEGALIDQKTMG-RGAPTRIEK-----AKIGLIQFQISPPKTDMENQVIITDYAQMDRALKEERQYLLEICKQIKA---------------------------------AGCNVLLIQKSILRDAVNELALHFLAKMKIMCIKDIEREDIEFYSRILGCRPVASVDHFN------ADALGYADLVEEIPTGGDGKVIKVTG-------VQN--PGHAV-----SILLRGSNKLVLEEADRSIHDALCVIRCLVK--KKALLPGGGAPEMEIAVKLR---NLAQTQHGATQYCWRAFADALELIPYTLAENAGLSPIHTVTELRNNHAN-GNS-----------SYGVNVRKGY--VTD-MVEEDVVQPLLVTASAIKQASECVRSILKIDDIVMAVR----------------------------------
Ce_epsilon -----MAQSSAQLLFDESGQPFIVMREQENQKRITGVEAVKSHILAARAVANTLRTSLGPRGLDKMLVSPDGD----VTITNDGATIMEKM-----DVQHHVAKLMVELSKSQDHEIGDGTTGVVVLAGALLEEAEKLIDR-GIHPIKIADGFDLACKKALE-TLDSISDKFPVE------NRERLVETAQTSLGSK--IVNRSLRQFAEIAVDAVLSVAD-------IESKDVN--FEMIKMEGKVGGRLEDTILVKGIVIDKTMSHPQMPKELKN------AKVAILTCPFEPPKPKTKHKLDITSTEDFKALRDYERETFETMIRQVKE---------------------------------SGATLAICQWG-----FDDEANHLLQANDLPAVRWVGGPEIELLAIATNARIVPRFSELS------KEKLGTAGLVREITFGAAKDRMLSIE---------QCPNNKAV-----TIFVRGGNKMIIDEAKRALHDALCVIRNLVR--DSRIVYGGGSAELAAAIQVA---KEADRIDGIEQYAFRAFADALESIPMALAENSGLAPIDALSDLKAKQIETGKS-----------SLGIDAVFAG--TND-MKEQKVIETLLSKREQISLATQVVRMILKIDDVRVPDDE---------------------------------
Ce_etha ------------------MMRPPIILLKDGTENKQGKGQIISNINACQVVADSIRTTLGPRGLDKLIVDSKGA----TTISNDGATILKLL-----DIVFPAASTMVDIARSQDAEVGDGTTSVVVLAAEILKQMKPFIED-GVHPQLLIRAIGKACEKTLK-NLADLEIKING--ET--ELREMLVKCAATTLSSK--LVSQERLFFANMIVDAVNTLD-------AHLP------LNMIGIKKVNGGNLHESRLIKGVAFQKAFSYAGFEMQPKKYS---NVKVALLNIELELKAEKENAEMRLTNVSDFQAVVDAEWNILYDKLQKIHD---------------------------------SGANVVLSKLP-----IGDVATQWFADRDMFCAGRIPQDDLDRLMSACGGSVLTTVSQID------DSVLGKCGKFYEQQVGSERYNFFEDCS-----------KAQAC-----TLLLRGGAEQFIAETERSLHDAIMIVRRAKK--NDSIVAGGGAIEMELSRLIR---EHSKGIEGKDQAFWMAYGQAFEIIPRQLCQNAGLDALDVLNKLRHRHAQG------------EKWAGIDIHREA--VGD-NLVACVWEPSIVKRNAITAATEAACLVLSIDQTVKNV-----------------------------------
Ce_gamma ---------------MRGAGQQPIIVLSQGTKRESGHQVQIGNINACKTIADVIRTSLGPRAMLKMLMDPMGG----IVMTNDGNAILREI-----TVKHPAAKSMIEIARTQDEETGDGTTSVIILAGEVMA-HAQTYLEQKTHPTLIIKAYRQALEDMIQWSENKFSKTVDITDD------AEIAKVVKSCLGTK--MISKWMDLAVNISIQAVKTIR------VEKAGVREIDIKRYCRIEKIPGGRIEDSQVVKGIVVNKDILHAKMRRRIEN------PRIVLLDCNLEYKKGESQTSLEIMREEDISAILEQEEQAIRKQCDEIIK---------------------------------LKPDLVFTEKG-----ISDLAQHFLLKAGITCLRRLKKTDNNRLARVCGARVVHDTSDLR-----DEDVGTKAQLFEVVKIADEYYTYVT-AE-----------TTTAC-----TVVLRGPSKDVINEVERNLQDSLHVVRNIMI--NPKLVPGGGALEMALSREIE---QQGAKMDGVKKWPYKAIGLALEVIPRTLIQNCGGSTIRKMTELRAIHAQNAENWTF----------GVDGTSGD--LVD-MNKLEIWDPLAVRIQVLKTAIETSVMLLRIDDIVSGTKKAVGGEKQEMMPQ---------------------
Ce_tetha -----------MAMKIPKS-GYNRFMKEGAQHFKGTDEAVQRNIEACTELASQIRSAYGPNGMNKMVINHIEK----LFVTNDAATILKEL-----EIQHPAARIIIMATEMQEKQIGDNTNTVVILAAALLEHAANLIHM-GMTPQEVAAGYEQAAEKALEILPTLVVK--EATDMK---NIEEVRQYIRSAITSK---QYDNEDIIADLVAKACVTTCPAN---------SFNFNVDNIRICKIIGSGVHTSTVMNGMVFKRGAEGEIREARDAR--------IAVYTCPFDLTQTETKGTVLIENADELRNFSKGEEAEVEEQVKAIADNARSSILAKFWLMNFSKGEEAEVEEQQVKAIADNGVKVVVAAGK-----FGDMYLHFLNKYKIMAVRLTSKFDLRRLCRTVGAQPQARICAPA------VNLLGHCDSVAVQEIGDENVVVFDKKSASNLNFLKFSETGKVA-----TIIIRGSSQSRIDDVERAVDDAVNTYKALTK--DGKLLAGAGAVEIELAKEIE---SFGAKAPGLEQYAIKKFAHALETLPKAIAENAGMPTTETLTKLYAEHVAGKK------------NAGIDIWKR---ETMDAVVNNIFDLYAGKRLAIKLATDAASTILKVDQIIMSKQATGGPKPRGPKAQDEDDDGMA-------------
Ce_zeta --------------------MSSIQCLNPKAELARHAAALELNISGARGLQDVMRSNLGPKGTLKMLVSGAGD----IKLTKDGNVLLHEM-----AIQHPTASMIAKASTAQDDVTGDGTTSTVLLIGELLKQAESLVLE-GLHPRIVTEGFEWANTKTLE-LLEKFK----KEAPV---ERDLLVEVCRTALRTK--LHQKLADHITECVVDAVLAIRRD-----GEE-----PDLHMVEKMEMHHDSDMDTTLVRGLVLDHGARHPDMPRH-VKDAY-----ILTCNVSLEYEKTEVNSGLFYKTAKEREALLAAEREFITRRVHKIIELKKKVIDNSPDGK--------------------NKGFVVINQKG-----IDPPSLDLLASEGILALRRAKRRNMERLQLAVGGEAVNSVDDLT------PEDLGWAGLVYEHSLGEEKYTFIEECR-----------APKSV-----TLLIKGPNKHTITQIKDAIHDGLRAVFNTIV--DKAVLPGAAAFEIAAYVMLK---KDVENLKGRAKLGAEAFAQALLVIPKTLAVNGGYDAQETLVKLIEEKTAA------------GPDIAVGLDLET---GGAVEPQGIWDNVTVKKNSISSATVLACNLLLVDEVMRAGMT---------------------------------
Gi_alfa ---------------------MTSNAIFLPGELNSGNSVRKENISATTALAGIIRTTLGPTGMDKMLIDSMG----EVTVTNDGATILQKL-----NVAHPAAKILVELSSLQDREVGDGTTSVVIFASEFLKEADELIGR-NMHPTIVIEGYQLALKKALN-YIEKRLKVNASALT----RENFLN-VALTSLSSK--IVSLTAEHFANIVVDAVFAVKH------ITEAGVTKYPIKSIGILKAHGGAARESYLVKG-FALHQSRASLQMPSSVR-----AAKIALLDFNLQQQRLAVGTQILITDASKMEGVRQMENDIVKKRIEVLLA---------------------------------AGATVVFTTGG-----IDDMAQKYLVEQGIMGVRRIPADDMKRIAKVTGGEILGTLADLDGEETLPPSCLGFAEEVIEERIADDNIIFIRGGK-----------GRATG-----SIILRGPNIHMVEEMERSIHDALCAVSKTLE--SDAVVAGGGCIETALSAYLE---EVARSIDNKTQLAVMAFSRALLAIPRQLAVNSALDATKLIAELRAVHARAILKETPAEEKEKLRHYGLDLQNGV--ICD-NVQAGVLEPMSNKLKSLSFAVEAAVTILRIDDSIRLNPE---------------------------------
Gi_bet ------------------MEQATSRILKEGGSQERGDDARLSTLVGAIAISDMVKTTMGPKGMDKILQSVSG----GMNITNDGATILKSV-----VVDNPAARVLIDISRVQDETVGDGTTSVCVLAGEILRQAQQLLAK-RMHPMTIIEGFRAATDVALK-ALESIAVDHKQDAAA--FHTDLLN-IARTTLSSK--ILTSVQEHFAKMAVKCVLNMEG------DTN-------LKNIQIIKKPGGTLLDSYVDDG--FLLDKRIGLSCPKEISNA---RVLVANTPMDSDK-IKILGSRVRVDSHTKLAEIEEAEKARIIAKCDKIAA---------------------------------HDINVFVNRQL-----IYDVPMQALSKKGIMVIEHADFDGVDRLSLVLNADIVSTFDTPN------SVKIGFCESVEEVLIGEDRLIKFSGLL-----------KKTCS-----TIVLRGASMHILDEAERSLHDALCVLSQTAAR-DSRVVLGAGCAETAMANAIE---KAAMKTQGKVSIAMEAFAKALRSIPVIIANNGGYDGEELVSKLRALHNAGKTD------------FGLDMRTGT--VMN-VRHAGITESYMCKQHVVLYAAEAAEQILRVD-----------------------------------------
Gi_epsilon MAQRINGAQLLGVSQDENGNPVYLMREGTEKKRARGLEAHKSNITIARALANTLRTSLGPRGMDKILVSGDRE----LTITNDGATILERM-----EVDNHIARLLVDLSKCQDNEIGDGTTGVVVLAGSLLEHAETLLDK-GIHPIRISDGYDMACDVAIK-HLESIATTYSFSAD----NKEPLIKAAMTSLGSK--VINRYHRTMAEVAVDAVFRVAD-------LQRNDVD--FELIKVRSKIGGKLEDIKIINGFLIDQEMSHPGMRKSVSH------AKIAVLTCPFEPPKPKTTYKIDVDSVEKYNTLYREEQQFFINMIEHLKE---------------------------------AGANFVVCQWG-----FDDEANHLLMQNDINAVRWVKGEDIEAIALITGARIIPRFEDIS------SDKLGYAEIVREVSLGTSSDKVMIFEGL-----QPQQTTADSVPHMISTVFIRGGNNMIIEEARRSLHDAMCVVRNLIR--DPRVIYGGGSAEISCSLAIA---EAAEHVGTVEQYALRAFSEALDIIPLTLARNSSIQPIETLAMVKAAQKKTGSH-----------HLGIDCMQRN--TID-MKEQSVFETLSSKVQQLLLATQVVRMILKIDEVITDEV----------------------------------
Gi_zeta --------------------MSAIHALNQKAEHLRRGEALDMNIDAAEKLTKLIRTNFGPAGTYKMLVSGAGD----IKITKDGAVLLSEL-----PINHPIAAFIATAATAQDDIVGDGTTTMVLLVGELLRQAARWLAE-DVHPRVLVDGFELAKARVIS-FLDSYKQPLPTEERA---RYDTLRSIAHTSLVTK--VHADLANLLSDIVTEAVLIVEKA-----AESKEQSFIDLHMVELMLMPSRLDVDTTLIKGLVMDHGSRQSELTCATMRSCF-----ILTLNVSLEYEKAEANTGFFYKNAEEMRELAKKERDYVDNKCRKIIQLKEQAFASYRETHGADA----------------ECNFVVLNQKG-----IDGVSLDMLAANGIFALRRVKRRNMERITLCCGGSAVCALDELK------VSDLGWADKIHEEMLGEEKYTFIEDIL-----------DPKSC-----TILIRGPTRHTLEQIKDAVRDGLRAVKNAIT--DKHYVAGAAAFEVAAAADLE---AYAKTVTGKTKLGIQAFADAICAIPKTLAKSAGLDPQECCIAVSEAATGS------------SINYGICLKTGK---PCDAVASGILDNVCVKHQLYHSSTVITTQLLLTDEILKAGR----------------------------------
Haloferax ---------------MASRMQQPLYILAEGTNRTHGRSAQDSNIRAGKAVAEAVRTTLGPRGMDKMLVDSSGE----VVITNDGATILEKM-----DIEHPAAQMLVEVSQTQEEEVGDGTTTAAVLTGELLAHAEDLLDD-DLHPTVIVEGYTEAARIAQD-AIDDMVLDVTLDDD-------LLRKVAESSMTGKG-TGDVTADVLAKHVVKAVQMVHE------DD---NGVFHRDDVRVLTRTGASSSATELVEGVVLDKEPVNENMPRSVSD------ATVAVLDMKLDVRKSEVDTEYNITSVDQLTAAIDAEDSELRGYAKALAD---------------------------------AGVDVVFCTKS-----IDDRVAGFLADAGILAFKSVKKSDARALARATGAKRLGSLSDLD------ESDLGRVDAVSIRSFGDDDLAFVEGGA-----------AAKAV-----TLFLRGGTEHVVYELERAIEDAVDVVVAAID--KGGVVPGAGATEIAIADRIR---SEAAGIEGRKQLAVEAYADAVEALPRTLAENTGMDPIDALVDLRARYETEGLA-----------GIISSGRSGE--IGD-PVELGVIDPVAVKREAIESATEAATMIVRIDDVIAAK-----------------------------------
Hs_alfa ----------------------MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIG----DVTITNDGATILKLL-----EVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQ-KIHPTSVISGYRLACKEAVR-YINENLIVNTDELG----RDCLIN-AAKTSMSSK--IIGINGDFFANMVVDAVLAIKY------TDIRGQPRYPVNSVNILKAHGRSQMESMLISG-YALNCVVGSQGMPKRIV-----NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILA---------------------------------TGANVILTTGG-----IDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTK-----------ARTSA-----SIILRGANDFMCDEMERSLHDALCVVKRVLE--SKSVVPGGGAVEAALSIYLE---NYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLSNGK--PRD-NKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPE---------------------------------
Hs_beta ---------------MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGR--DASLMVTNDGATILKNI-----GVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAK-KIHPQTIIAGWREATKAARE-ALLSSAVDHGSDEVK--FRQDLMN-IAGTTLSSK--LLTHHKDHFTKLAVEAVLRLKG------SGN-------LEAIHIIKKLGGSLADSYLDEG--FLLDKKIGVNQPKRIENA---KILIANTGMDTDK-IKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILK---------------------------------HGINCFINRQL-----IYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPE------LVKLGSCKLIEEVMIGEDKLIHFSGVA-----------LGEAC-----TIVLRGATQQILDEAERSLHDALCVLAQTVK--DSRTVYGGGCSEMLMAHAVT---QLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTT------------AGLDMREGT--IGD-MAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAA-----------------------------------
Hs_delta ------MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGD----VTITNDGATILKQM-----QVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQK-GIHPTIISESFQKALEKGIE-ILTDMSRPVELS------DRETLLNSATTSLNSK--VVSQYSSLLSPMSVNAVMKVID------PATATSVD--LRDIKIVKKLGGTIDDCELVEGLVLTQKVS--NSGITRVEK-----AKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKK---------------------------------TGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFT------ADMLGSAELAEEVNLNGSGKLLKITG-------CAS--PGKTV-----TIVVRGSNKLVIEEAERSIHDALCVIRCLVK--KRALIAGGGAPEIELALALT---EYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQ-GEK-----------TAGINVRKGG--ISN-ILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR-----------------------------------
Hs_epsilon MSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGD----VTVTNDGATILSMM-----DVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDR-GIHPIRIADGYEQAARVAIE-HLDKISDSVLVDIK----DTEPLIQTAKTTLGSK--VVNSCHRQMAEIAVNAVLTVAD-------MERRDVD--FELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVED------AKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKE---------------------------------TGANLAICQWG-----FDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELT------AEKLGFAGLVQEISFGTTKDKMLVIE---------QCKNSRAV-----TIFIRGGNKMIIEEAKRSLHDALCVIRNLIR--DNRVVYGGGAAEISCALAVS---QEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNP-----------ALGIDCLHKG--TND-MKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGES---------------------------------
Hs_etha ------------------MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGK----ATISNDGATILKLL-----DVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEE-GLHPQIIIRAFRTATQLAVN-KIKEIAVTVKKADKV--EQRKLLEKCAMTALSSK--LISQQKAFFAKMVVDAVMMLD-------DLLQ------LKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYH---NPKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHH---------------------------------SGAKVVLSKLP-----IGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALS------ADVLGRCQVFEETQIGGERYNFFTGCP-----------KAKTC-----TFILRGGAEQFMEETERSLHDAIMIVRRAIK--NDSVVAGGGAIEMELSKYLR---DYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQG------------GTWYGVDINNED--IAD-NFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNP-----------------------------------
Hs_gamma ------------------MGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGG----IVMTNDGNAILREI-----QVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLS-VAEHFLEQQMHPTVVISAYRKALDDMIS-TLKKISIPVDISDS------DMMLNIINSSITTK--AISRWSSLACNIALDAVKMVQ------FEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKN------PRIVLLDSSLEYKKGGSQTDIEITREEDFTRILQMEEEYIQQLCEDIIQ---------------------------------LKPDVVITEKG-----ISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELR-----EDDVGTGAGLLEIKKIGDEYFTFITDCK-----------DPKAC-----TILLRGASKEILSEVERNLQDAMQVCRNVLL--DPQLVPGGGASEMAVAHALT---EKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-ENCETW----------GVNGETGT--LVD-MKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSG------------------------------------
Hs_theta -----------MALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPKGMNKMVINHLEK----LFVTNDAATILREL-----EVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRI-GLSVSEVIEGYEIACRKAHEILPNLVCC--SAKNLR---DIDEVSSLLRTSIMSK---QYGNEVFLAKLIAQACVSIFPD----------SGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAK--------IAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAD---------------------------------TGANVVVTGGK-----VADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPV------LEEMGHCDSVYLSEVGDTQVVVFKHE----------KEDGAIS-----TIVLRGSTDNLMDDIERVVDDGVNTFKVLTR--DKRLVPGGGATEIELAKQIT---SYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNK------------NVGLDIEAEV-PAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPA---------------------------------
Hs_zeta1 --------------------MAAIKAVNSKAEVARAR-QLWLSIYAPPRVQDVLRTNLGPKGTMKMLVSGAGD----IKLTKDGNVLLDEM-----QIQHPTASLIAKVATAQDGVTGDGTTTNVLIIGELLKQADLYISE-GLHPRIIAEGFEAAKIKALE-VLEEVK----VTKEM---KRKILLDVARTSLQTK--VHAELADVLTEVVVDSLFPVRRP-----PYP-----IDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKR-VEDAF-----ILICNVSLEYEKTEVNSAFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQS------------------------NKGFVVINQKG-----IDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLT------VDCLGHAGLVYEYTLGEEKFTFIEECV-----------NPCSV-----TLLVKGPNKHTLTQVKDAIRDGLRAIKNAIE--DGCMVPGAGAIEVAMAEALV---TYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVES------------KQLVGVDLNTGE---PMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS---------------------------------
Hs_zeta2 --------------------MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGD----IKLTKDGNVLLDEM-----QIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISE-GLHPRIIAEGFEAAKIKALE-VLEEVK----VTKEM---KRKILLDVARTSLQTK--VHAELADVLTEVVVDSVLAVRRP-----GYP-----IDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKR-VEDAF-----ILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQS------------------------NKGFVVINQKG-----IDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLT------VDCLGHAGLVYEYTLGEEKFTFIEECV-----------NPCSV-----TLLVKGPNKHTLTQVKDAIRDGLRAIKNAIE--DGCMVPGAGAIEVAMAEALV---TYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVES------------KQLVGVDLNTGE---PMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK------------------------------
Methanococ -----------------MAANQPVVVLPENVKRFMGRDAQRMNILAGRIIGETVRSTLGPKGMDKMLVDDLGD----IVVTNDGVTILKEM-----SVEHPAAKMLIEVAKTQEKEVGDGTTTAVVIAGELLRKAEELLDQ-NVHPTIVIKGYQLAVQKAQE-VLKEIAMDVKADDK------EILHKIAMTSITGK--GAEKAKEKLGEMIVEAVTAVVD------E--SGK--VDKDLIKIEKKEGASVDETELINGVLIDKERVSPQMPKKIEN------AKIALLNCPIEVKETETDAEIRITDPTKLMEFIEQEEKMLKDMVDTIKA---------------------------------SGANVLFCQKG-----IDDLAQHYLAKEGILAVRRVKKSDMEKLSKATGANVVTNIKDLK------AEDLGEAGIVEERKIAGDAMIFVEECK-----------HPKAV-----TMLIRGTTEHVIEEVARAVDDAIGVVACTIE--DGKIVAGGGAAEIELAMKLR---DYAEGVSGREQLAVRAFADALEVVPRTLAENAGLDAIEMLVKLRAKHAEGNNA-----------YYGLNVFTGD--VEN-MTENGVVEPLRVKTQAIQSATEATEMLLRIDDVIAAEKLSGGSGGDMGDMGGMGGMGGMM------------
Mm_alfa ----------------------MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIG----DVTITNDGATILKLL-----EVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQ-KIHPTSVISGYRLACKEAVR-YINENLIINADELG----RDCLTN-TAKTSMSSK--IIGINGDYFANMVVDAVLAVKY------TDARGQPRYPINSVNILKAHGRSQIESMLING-YALNCVVGSQGMPKRIV-----NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILA---------------------------------TGANVILTTGG-----IDDMCLKYFVEAGAMAVRRVLKRDLKCVAKASGATILSTLANLEGEETFEVTMLGQAEEVVQERICDDELILIKNTK-----------ARTSA-----SIILRGANDFMCDEMERSLHDALCVVKRVLE--SKSVVPGGGAVEAALSIYLE---NYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLVHGK--PRD-NKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPECKDDKHGSYENAVHSGALDD-------------
Mm_beta ----------------------MEGPLSVFGDRSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIG----DVTITNDGATILKLL-----EVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQ-KIHPTSVISGYRLACKEAVR-YINENLIINTDELG----RDCLIN-AAKTSMSSK--IIGINGDYFANMVVDAVLAVKY------TDARGQPRYPVNSVNILKAHGRSQIESMLING-YALNCVVGSQGMPKRIV-----NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILA---------------------------------TGANVILTTGG-----IDDMYLKYFVEAGAMAVRRVLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQAEEVVQERICDDELILIKNTK-----------ARTSA-----SIILRGANDFMCDEMERSLHDALCVVKRVLE--LKSVVPGGGAVEAALSIYLE---NYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLVHGK--PRD-NKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYENAVHSGALDD-------------
Mm_delta ------MPENVASRSGAPTAGPGSRGKSAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGD----VTITNDGATILKQM-----QVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQK-GIHPTIISESFQKALEKGLE-ILTDMSRPVQLS------DRETLLNSATTSLNSK--VVSQYSSLLSPMSVNAVMKVID------PATATSVD--LRDIKIVKKLGGTIDDCELVEGLVLTQKVA--NSGITRVEK-----AKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKK---------------------------------TGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDVEREDIEFICKTIGTKPVAHIDQFT------ADMLGSAELAEEVSLNGSGKLFKITG-------CTS--PGKTV-----TIVVRGSNKLVIEEAERSIHDALCVIRCLVK--KRALIAGGGAPEIELALRLT---EYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQ-GEK-----------TTGINVRKGG--ISN-ILEEMVVQPLLVSVSALTLATETVRSILKIDDVVNTR-----------------------------------
Mm_epsilon ------MASVGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGD----VTITNDGATILSMM-----DVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDR-GIHPIRIADGYEQAARIAIQ-HLDKISDKVLVDIN----NPEPLIQTAKTTLGSK--VINSCHRQMAEIAVNAVLTVAD-------MERRDVD--FELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVD------AKIAILTCPFEPPKPKTKHKLDVMSVEDYKALQKYEKEKFEEMIKQIKE---------------------------------TGANLAICQWG-----FDDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIVPRFSELT------SEKLGFAGVVQEISFGTTKDKMLVIE---------KCKNSRAV-----TIFIRGGNKMIIEEAKRSLHDALCVIRNLIR--DNRVVYGGGAAEISCALAVS---QEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKESNP-----------ALGIDCLHKG--SND-MQYQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGES---------------------------------
Mm_etha ------------------MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGK----ATISNDGATILKLL-----DVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEE-GLHPQIIIRAFRTATQLAVN-KIKEIAVTVKKQDKV--EQRKMLEKCAMTALSSK--LISQQKVFFAKMVVDAVMMLD-------ELLQ------LKMIGIKKVQGGALEESQLVAGVAFKKTFSYAGFEMQPKKYK---NPKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHQ---------------------------------SGAKVILSKLP-----IGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALV------PDVLGHCQVFEETQIGGERYNFFTGCP-----------KAKTC-----TIILRGGAEQFMEETERSLHDAIMIVRRAIK--NDSVVAGGGAIEMELSKYLR---DYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQG------------GMWYGVDINNEN--IAD-NFQAFVWEPAMVRINALTAASEAACLIVSVDETIKNP-----------------------------------
Mm_gamma -----------------MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGG----IVMTNDGNAILREI-----QVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLS-VAEHFLEQQMHPTVVISAYRMALDDMIS-TLKKISTPVDVNNR------EMMLSIINSSITTK--VISRWSSLACNIALDAVKTVQ------FEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKN------PRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIHQLCEDIIQ---------------------------------LKPDVVITEKG-----ISDLAQHYLMRANVTAIRRVRKTDNNRIARACGARIVSRPEELR-----EDDVGTGAGLLEIKKIGDEYFTFITDCK-----------DPKAC-----TILLRGASKEILSEVERNLQDAMQVCRNVLL--DPQLVPGGGASEMAVAHALT---EKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-ESCETW----------GVNGETGT--LVD-MKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSG------------------------------------
Mm_theta -----------MALHVPKAPGFAQMLKDGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINRLEK----LFVTNDAATILREL-----EVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRI-GLSVSEVISGYEIACKKAHEILPELVCC--SAKNLR---DVDEVSSLLRTSIMSK---QYGSETFLAKLIAQACVSIFPD----------SGNFNVDNIRVCKILGSGIYSSSVLHGMVFKKETEGDVTSVKDAK--------IAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAG---------------------------------TGANVIVTGGK-----VADIALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPKLTPPV------QEEMGHCDSVYLSEVGDTQVVVFKHE----------KEDGAIS-----TIVLRGSTDNLMDDIERAVDDGVNTFKVLTR--DKRLVPGGGATEIELAKQIT---SYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQEGNK------------NVGLDIEAEV-PAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPA---------------------------------
Mm_zetaA --------------------MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGD----IKLTKDGNVLLHEM-----QIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISE-GLHPRIITEGFEAAKEKALQ-FLEQVK----VSKEM---DRETLIDVARTSLRTK--VHAELADVLTEAVVDSILAIRKK-----DEP-----IDLFMVEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKR-VENAY-----ILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKKKVCGDS------------------------DKGFVVINQKG-----IDPFSLDALAKEGIVALRRAKRRNMERLTLACGGIALNSFDDLN------PDCLGHAGLVYEYTLGEEKFTFIEKCN-----------NPRSV-----TLLVKGPNKHTLTQIKDAIRDGLRAVKNAID--DGCVVPGAGAVEVALAEALI---KYKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKVQAEHSES------------GQLVGVDLSTGE---PMVAAEMGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS---------------------------------
Mm_zetaB --------------------MAAIKIANPGAEVTRSQAALAVNICAARGLQDVLRPTLGPKGALKMLVSGAGD----IKLTKDGNVLLHEM-----QIQHPTASIIAKVAAAQDHVTGDGTTSNVLIIGELLKQADLYISK-GLHPRIITEGFDVAKTKALE-VLDEIK----VQKEM---KREILLDVARTSLQTK--VHAELADILTEAVVDSVLAIRRP-----GVP-----IDLFMVEIVEMRHKSETDTQLIRGLVLDHGARHPRMRKQ-VRDAY-----ILTCNVSLEYEKTEVSSGFFYKTVEEKEKLVKAERKFIEDRVQKIIDLKQKVCAES------------------------NKGFVVINQKG-----IDPVSLEMLAKHNIVALRRAKRRNLERLTLACGGLAVNSFEGLS------EECLGHAGLVFEYALGEEKFTFIEDCV-----------NPLSV-----TLLVKGPNKHTLIQIKDALRDGLRAVKNAIE--DGCVVPGAGAVEVAIAEALV---NYKHRVQGRVRLGIQAFADALLIIPKVLAQNSGYDLQETLIKIQTKHAES------------KELLGIDLNTGE---PMAAAEAGIWDNYCVKKHLLHSCTVIATNILLVDEIMRAGMS---------------------------------
Pyrococcusalf ---------------MAQLSGQPVVILPEGTQRYVGRDAQRLNILAARIIAETVRTTLGPKGMDKMLVDSLGD----IVVTNDGATILDKI-----DLQHPAAKMMVEVAKTQDKEAGDGTTTAVVIAGELLRKAEELLDQ-NIHPSIIIKGYALAAEKAQE-ILDEIAIRVDPDDE------ETLLKIAATSITGK--NAESHKELLAKLAVEAVKQVAE------KK-DGKYVVDLDNIKFEKKAGEGVEESELVRGVVIDKEVVHPRMPKRVEN------AKIALINEALEVKKTETDAKINITSPDQLMSFLEQEEKMLKDMVDHIAQ---------------------------------TGANVVFVQKG-----IDDLAQHYLAKYGIMAVRRVKKSDMEKLAKATGAKIVTNVKDLT------PEDLGYAEVVEERKLAGENMIFVEGCK-----------NPKAV-----TILIRGGTEHVIDEVERALEDAVKVVKDVME--DGAVLPAGGAPEIELAIRLD---EYAKQVGGKEALAIENFADALKIIPKTLAENAGLDTVEMLVKVISEHKN-RGL-----------GIGIDVFEGK--PAD-MLEKGIIEPLRVKKQAIKSASEAAIMILRIDDVIAAKATKPEGGQGGGMPGGMGGMDMGM------------
Sc_alfa --------------MSQLFNNSRSDTLFLGGEKISGDDIRNQNVLATMAVANVVKSSLGPVGLDKMLVDDIG----DFTVTNDGATILSLL-----DVQHPAGKILVELAQQQDREIGDGTTSVVIIASELLKRANELVKN-KIHPTTIITGFRVALREAIR-FINEVLSTSVDTLG----KETLIN-IAKTSMSSK--IIGADSDFFSNMVVDALLAVKT------QNSKGEIKYPVKAVNVLKAHGKSATESLLVPG-YALNCTVASQAMPKRIAGG---NVKIACLDLNLQKARMAMGVQINIDDPEQLEQIRKREAGIVLERVKKIID---------------------------------AGAQVVLTTKG-----IDDLCLKEFVEAKIMGVRRCKKEDLRRIARATGATLVSSMSNLEGEETFESSYLGLCDEVVQAKFSDDECILIKGTS-----------KHSSS-----SIILRGANDYSLDEMERSLHDSLSVVKRTLE--SGNVVPGGGCVEAALNIYLD---NFATTVGSREQLAIAEFAAALLIIPKTLAVNAAKDSSELVAKLRSYHAASQMAKPEDVKRRSYRNYGLDLIRGK--IVD-EIHAGVLEPTISKVKSLKLALEACVAILRIDTMITVD-----------------------------------
Sc_beta ---------------------MSVQIFGDQVTEERAENARLSAFVGAIAVGDLVKSTLGPKGMDKLLQSAS---SNTCMVTNDGATILKSI-----PLDNPAAKVLVNISKVQDDEVGDGTTSVTVLSAELLREAEKLIDQSKIHPQTIIEGYRLASAAALD-ALTKAAVDNSHDKTM--FREDLIH-IAKTTLSSK--ILSQDKDHFAELATNAILRLKG------STN-------LEHIQIIKILGGKLSDSFLDEG--FILAKKFGNNQPKRIENA---KILIANTTLDTDK-VKIFGTKFKVDSTAKLAQLEKAEREKMKNKIAKISK---------------------------------FGINTFINRQL-----IYDYPEQLFTDLGINSIEHADFEGVERLALVTGGEVVSTFDEPS------KCKLGECDVIEEIMLGEQPFLKFSGCK-----------AGEAC-----TIVLRGATDQTLDEAERSLHDALSVLSQTTK--ETRTVLGGGCAEMVMSKAVD---TEAQNIDGKKSLAVEAFARALRQLPTILADNAGFDSSELVSKLRSSIYNGIST------------SGLDLNNGT--IAD-MRQLGIVESYKLKRAVVSSASEAAEVLLRVDNIIRARPRTANRQHM--------------------------
Sc_delta ----------------MSAKVPSN---ATFKNKEKPQEVRKANIIAARSVADAIRTSLGPKGMDKMIKTSRGE----IIISNDGHTILKQM-----AILHPVARMLVEVSAAQDSEAGDGTTSVVILTGALLGAAERLLNK-GIHPTIIADSFQSAAKRSVD-ILLEMCHKVSLS------DREQLVRAASTSLSSK--IVSQYSSFLAPLAVDSVLKISD-------ENSKNVD--LNDIRLVKKVGGTIDDTEMIDGVVLTQTAIKSAGGPTRKEK-----AKIGLIQFQISPPKPDTENNIIANDYRQMDKILKEERAYLLNICKKIKK---------------------------------AKCNVLLIQKSILRDAVNDLALHFLSKLNIMVVKDIEREEIEFLSKGLGCKPIADIELFT------EDRLGSADLVEEIDSDGS-KIVRVTG-------IRNNNARPTV-----SVVIRGANNMIIDETERSLHDALCVIRCLVK--ERGLIAGGGAPEIEISRRLS---KEARSMEGVQAFIWQEFASALEVIPTTLAENAGLNSIKVVTELRSKHEN-GEL-----------NDGISVRRSG--TTN-TYEEHILQPVLVSTSAITLASECVKSILRIDDIAFSR-----------------------------------
Sc_epsilon ----MPDLSNAIVAQDEMGTPFIIVKDQGNKKRQHGLEAKKSHILAARSVDSIIKTSLGPRGLDKILISPDGE----ITITNDGATILTQM-----ELDNEIAKLLVQLSKSQDDEIGDGTTGVVVLASALLDQALELIQK-GIHPIKIANGFDEAAKLAIS-KLEETCDDISASNDE--LFRDFLLRAAKTSLGSK--IVSKDHDRFAEMAVEAVINVMD-------KDRKDVD--FDLIKMQGRVGGSISDSKLINGVILDKDFSHPQMPKCVLPKEGSDGVKLAILTVHLNLLKPKTKHKLDISSVEEYQKLQTYEQDKFKEMIDDVKK---------------------------------AGADVVICQWG-----FDDEANHLLIQNDLPAVRWVGGQELEHIAISTNGRIVPRFQDLS------KDKLGTCSRIYEQEFGTTKDRMLIIE---------QSKETKTV-----TCFVRGSNKMIVDEAERALHDSLCVVRNLVK--DSRVVYGGGAAEVTMSLAVS---EEADKQRGIDQYAFRGFAQALDTIPMTLAENSNLDPIGTLSTLKSKQLKEKIS-----------NIGVDCLGYG--SND-MKELFVVDPFIGKKQQILLATQLCRMILKIDNVIISGK----------------------------------
Sc_etha --------------MNFGSQTPTIVVLKEGTDASQGKGQIISNINACVAVQEALKPTLGPLGSDILIVTSNQK----TTISNDGATILKLL-----DVVHPAAKTLVDISRAQDAEVGDGTTSVTILAGELMKEAKPFLEE-GISSHLIMKGYRKAVSLAVE-KINELAVDITS-EKS--SGRELLERCARTAMSSK--LIHNNADFFVKMCVDAVLSLDR------NDLD------DKLIGIKKIPGGAMEESLFINGVAFKKTFSYAGFEQQPKKFN---NPKILSLNVELELKAEKDNAEVRVEHVEDYQAIVDAEWQLIFEKLRQVEE---------------------------------TGANIVLSKLP-----IGDLATQFFADRNIFCAGRVSADDMNRVIQAVGGSIQSTTSDIK------PEHLGTCALFEEMQIGSERYNLFQGCP-----------QAKTC-----TLLLRGGAEQVIAEVERSLHDAIMIVKRALQ--NKLIVAGGGATEMEVSKCLR---DYSKTIAGKQQMIINAFAKALEVIPRQLCENAGFDAIEILNKLRLAHSKG------------EKWYGVVFETEN--IGD-NFAKFVWEPALVKINALNSATEATNLILSVDETITNK-----------------------------------
Sc_gamma -------------------MQAPVVFMNASQERTTGRQAQISNHAAAKAVADVIRTCLGPKAMLKMLLDPMGG----LVLTNDGHAILREI-----DVAHPAAKSMLELSRTQERRGGDGTTTVIILAGEILAQCAPYFIEKNIHPVIIIQALKKALTDALE-VIKQVSKPVDVEND------AAMKKLIQASIGTK--YVIHWSEKMCELALDAVKTVRKDLGQTVEGEPNFEIDIKRYVRVEKIPGGDVLDSRVLKGVLLNKDVVHPKMSRHIEN------PRVVLLDCPLEYKKGESQTNIEIEMEEDWNRILLIEEEQVQLMCEQILA---------------------------------VR-TLVITEKG-----VSDLAQHYLLKGGCSVLRRVKKSDNNRIARVTGATIVNRVEDLK-----ESDVGTNCGLFKVEMIGDEYFSFLDNCK-----------EPKAC-----TIMLRGGSKDILNEIDRNLQDAMAVARNVML--SPSLSPGGGATEMAVSVKLA---EKAKQLEGIQQWPYQAVADAMECIPRTLIQNAGGDPIRLLSQLRAKHAQ--ANFTT----------GIDGDKGK--IVD-MVSYGIWEPEVIKQQSVKTAIESACLLLRVDDIVSG------------------------------------
Sc_theta -----------MSLRLPQN-PNAGLFKQGYNSYSNADGQIIKSIAAIRELHQMCLTSMGPCGRNKIIVNHLGK----IIITNDAATMLREL-----DIVHPAVKVLVMATEQQKIDMGDGTNLVMILAGELLNVSEKLISM-GLSAVEIIQGYNMARKFTLKELDEMVVG--EITDKN---DKNELLKMIKPVISSK---KYGSEDILSELVSEAVSHVLPVAQ----QAGEIPYFNVDSIRVVKIMGGSLSNSTVIKGMVFNREPEGHVKSLSEDKKH-----KVAVFTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQIDAMMKEIAD---------------------------------MGVECIVAGAG-----VGELALHYLNRYGILVLKVPSKFELRRLCRVCGATPLPRLGAPT------PEELGLVETVKTMEIGGDRVTVFKQEQ---------GEISRTS-----TIILRGATQNNLDDIERAIDDGVAAVKGLMKPSGGKLLPGAGATEIELISRIT---KYGERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYAAHNVTEPGAVK----TDHLYKGVDIDGESDEGVKDIREENIYDMLATKKFAINVATEAATTVLSIDQIIMAKKAGGPRAPQGPRPGNWDQED---------------
Sc_zeta ---------------------MSLQLLNPKAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLKMLVDGAGN----IKLTKDGKVLLTEM-----QIQSPTAVLIARAAAAQDEITGDGTTTVVCLVGELLRQAHRFIQE-GVHPRIITDGFEIARKESMK-FLDEFKIS-KTNLSN---DREFLLQVARSSLLTK--VDADLTEVLTPIVTDAVLSVYDA-----QADN----LDLHMVEIMQMQHLSPKDTTFIKGLVLDHGGRHPDMPTR-VKNAY-----VLILNVSLEYEKTEVNSGFFYSSADQRDKLAASERKFVDAKLKKIIDLKNEVCGMDP-----------------------DKGFVIINQKG-----IDPMSLDVFAKHNILALRRAKRRNMERLQLVTGGEAQNSVEDLS------PQILGFSGLVYQETIGEEKFTYVTENT-----------DPKSC-----TILIKGSTHYALAQTKDAVRDGLRAVANVLK--DKNIIPGAGAFYIALSRYLRSANMNKLGAKGKTKTGIEAFAEALLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDS-------DETRYVGVDLNIGD---SCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLRAGRS---------------------------------
Sulfolobus_beta -MLSAVEKMSTTATVATTPEGIPVIILKEGSSRTYGKEALRINIAAVKAVEEALKSTYGPRGMDKMLVDSLGD----ITITNDGATILDKM-----DLQHPAAKLLVQIAKGQDEETADGTKTAVILAGELVKKAEELLYK-EIHPTIIVSGFKKAEEQALK-TIEEIAQKVSVNDM------DILKKVAMTSLNSK--AVAGAREYLADIVAKAVTQVAE------LR-GDRWYVDLDNIQIVKKHGGSINDTQIIYGIVVDKEVVHPGMPKRVEN------AKIALLDASLEVEKPELDAEIRINDPTQMKKFLEEEENLLKEKVDKIAA---------------------------------TGANVVICQKG-----IDEVAQHYLAKKGILAVRRAKKSDLEKLARATGGRVVSNIDELT------PQDLGYAALVEERKVGEDKMVFVEGAK-----------NPKAV-----SILIRGGLERVVDETERALRDALGTVADVIR--DGRAVAGGGAVELEIAKRLR---KYAPQIGGKEQLAIEAYASALENLVMILIENGGYDPIDLLVKLRSAHENEANK-----------WYGINVFTGQ--VED-MWKLGVIEPAVVKMNAIKAATEAATLILRIDDLIAAGKKSESKGGESKSEEKKEED----------------
Tv_alfa ------------------MLPVTPGSLKIDGQRQQGENVRVQNVRAAMAVANVVRSSLGPIGLDKMLVDDIG----EVTITNDGATILNHL-----DVQHPAGKVLIQLSELQDREVGDGTTTVVLLAAELLRLGQDLINK-KVHANTIITGYRAAAKKAIA-FLKKSCAVSNDNLD----REILLK-VAKTSMNSK--ILNAYSDFFGNMVVDACLAVKT------PAG----KCPTNRVNIVKSLGKSLPESTIVTAGVALNATRATEAFPRRLE-----KVKVAVLDFGLQRTRLPMGIQFRLHDASKLEAIQQEEVNAAERAVQAILK---------------------------------AGANVIVTSKT-----IDEASLKPLVKAGAIGIRHVSDAEIAHLARSTGATVVSQLISEDGGETFDPAWLGEAELIEQVPVGDNQMTIFRGCA-----------KENSA-----SIVLRGPNTFTLEEANRSLRDALFAVKRVIE--SKHVVAGGGAVEAALSVYLS---QIAKDYEGKEQVAMLKFGEALLVIPKILANNAALDSIDLVAKLRAVHYDAQQK-------GEKCFAALDLVNGK--IRD-GMKDGVIEPGMGSLN-------QTYEIL--------------------------------------------
Tv_delta -------------MSQQSAPAASATNPPAFQGQDRPTDVRMSCILAAKSVADAVRSSLGPRGMDKLIQEKNGE----VIITNDGATILKHM-----GAAHPAAKLMVSMSQAQDVAAGDGTTSVVIFAGAFLSACKTLLER-KLHPSLVSDALRIATDEAIK-ILDQMRIPFGQGETFTEQEREILIDSARTSLSSK--LASQWSDILAPLAVDAVLRVHD---------GKHVD--LNDIRVVQRVGGVIDDSELVDGVVFPHHFQRQSGDARKINN-----AKIALIQFQISPPKTDMESQVILNDYAQMDRVQREQRKYILNIVNAIAK---------------------------------TGANVILLQKSVLRDAISDTALHFLNKKGIIVVKDIDREEVDFVCRTIGCQPIASVEGLS------ADKLGFAETVEEVTTAGG-AIIKIMG-------LKK--VSKTV-----TVLLRGSNELIIGEAERSLHDALCVIRSLVY--ERYLLPGGGAPEVELAIKLA---KKADEIGGEIGHCIRAFADSLDIVPYTLAENAGLAPLDVVTQLREAHSS-GKM-----------YYGVSVVACG--PAD-MKEEEVLQPYLVTKSAVTFASETVRMILKVDDILATR-----------------------------------
Tv_etha ------------------MIRPPIILLREGVDQSQGLGQLISNINACHAIGEILASTLGPRGMDKLIHNSNNRR---AIVTNDGATVMKEL-----DIVHPAAQLLVDVAKSQDEEIGDGTTSVIVLSTSLLDAAKDFLED-GVHPQFICRCYRTALNAALK-KLDEVAVTIDG------SQREVLEQCAATTLRSK--LVSDSRYFFAPMIVDAVLQLD-------EDMR------LNDLGVKLVKGGSLQDSFFVPGVAFERTFSYAGFEQQPKHFK---NPKILLLNVELELKAEGTGAEVRVEDAKEFQEVVDAEWAIIFRKLNDCLN---------------------------------SGANIVISKKP-----IGDVATQFFADHDIFSAGRVPDEDFNRLAKCTGASILSTTSNIE------AKNLGTCADFEERQVGSKRFNIFTGG------------NGRAA-----TIVLRGGAEQFLEEAGRSIHDAIMIVRRAKK--AQRIVGGGGAIEMVISKHLH---EIALKMDGKAQLIVEAFGDALEAIPRSLTNNAGFDSFETLNKLRSAHEKAD-----------GVWAGVDIETGG--VLN-AVENFIWEPLVVKKNALKAACEAACTILSVDETVQIPQH---------------------------------
Tv_zeta --------------------MAAVSQLNSQAELYRHNQALSMNLNASHSLADILKTNLGPCGTLKMLVGGAGD----VQLTKDGTVLLKNL-----TIIHPTAIMISRAAAAQDENTGDGTTSTIILIDAMLKQCERRLAE-GVHPRVLTTGLEDARDEALR-FIEKFK----TTPKV---DRDFLLNVARTSLCTK--LPPELIDQLTEIVTDAVLAIKRD-----GEK-----VNLFMVEQLTMMSKLASDTALIRGLVLDHGFRHPSMKRD-MHNVY-----ILTCNVSLEFENTEVNTQFASNAADMREKMAEAERKFVDARVQKIIDLN-KVCTNG-------------------------EDFLVANMKG-----IDLPSLEKLQRAGISAVRRAKLRNMERLTLACGGRQMNSVENLE------PDCLGWAGHVYETIVGEDHWTFIEDVK-----------APRSV-----TILMRGPNNHTLKQMQDAVRDGLRAVNNAIE--DACAIAGAGAFEAALCAHLH---EYKKSVSGKNRLGIEAFAEALLEIPRVLAQNAGHDAVDCLVALQAAADK-------------GEVKGIDLETGE---LLDPKEKGIWDNYSVKRQQLQSAPLVATQLLLVDEVLRAGV----------------------------------
sulfolobus ----------------MAA---PVLLLKEGTSRTTGRDALRNNILAAKTLAEMLRSSLGPKGLDKMLIDSFGD----VTITNDGATIVKDM-----EIQHPAAKLLVEAAKAQDAEVGDGTTSAVVLAGALLEKAESLLDQ-NIHPTIIIEGYKKAYNKALE-LLPQLGTRIDIKDLNSSVARDTLRKIAFTTLASKFIAEGAELNKIIDMVIDAIVNVAE------PLPNGGYNVSLDLIKIDKKKGGSIEDSVLVKGLVLDKEVVHPGMPRRVTK------AKIAVLDAALEVEKPEISAKISITSPEQIKAFLDEESKYLKDMVDKLAS---------------------------------IGANVVICQKG-----IDDIAQHFLAKKGILAVRRVKRSDIEKLEKALGARIISSIKDAT------PEDLGYAELVEERRVGNDKMVFIEGAK-----------NLKAV-----NILLRGSNDMALDEAERSINDALHALRNILL--EPVILPGGGAIELELAMKLR---EYARSVGGKEQLAIEAFADALEEIPLILAETAGLEAISSLMDLRARHAK-GLS-----------NTGVDVIGGK--IVDDVYALNIIEPIRVKSQVLKSATEAATAILKIDDLIAAAPLKSEKKGGEGSKEESGGEGGSTPSLGD-------
thermoplasm -----------------MIAGQPIFILKEGTKRESGKDAMKENIEAAIAISNSVRSSLGPRGMDKMLVDSLGD----IVITNDGVTILKEM-----DVEHPAAKMMVEVSKTQDSFVGDGTTTAVIIAGGLLQQAEALINQ-NVHPTVISEGYRMASEEAKR-IIDEISTKIGKDEK------ELLIKLAQTSLNSK--SASVAKDKLAEISYEAVKSVAE------LR-DGKYYVDFDNIQVVKKQGGAIDDTALINGIIVDKEKVHPGMPDVVKN------AKIALLDAPLEIKKPEFDTNLRIEDPSMIQKFLAQEENMLREMVEKIKS---------------------------------VGANVVITQKG-----IDDMAQHYLSKEGIYAVRRVKKSDMDKLAKATGATVVSTIDEIS------ASDLGSADRVEQVKVGDDYMTFVTGCK-----------NPKAV-----SVLVRGETEHVVDEMERSITDSLHVVASALE--DGAYTAGGGATAAEIAVRLR---SYAQKIGGRQQLAIEKFADAIEEVPRALAENAGLDPIDIILKLRAEHAK-GNK-----------YAGVNVFSGE--IED-MVNNGVIEPIRVGKQAIESATEAAIMILRIDDVIATKSSGSSSNPPKSPSSESSSGED--------------
;
end;
begin trees;
tree FaresWolfeCCT = (((((Hs_theta:0.01,Mm_theta:0.03)5:0.24,Ce_tetha:0.29)4:0.06,At_theta:0.38)3:0.03,Sc_theta:0.39)2:0.33,((((((((Hs_zeta1:0.03,Hs_zeta2:0.00)13:0.06,Mm_zetaA:0.06)12:0.03,Mm_zetaB:0.10)11:0.09,Ce_zeta:0.23)10:0.02,At_zeta:0.26)9:0.02,Sc_zeta:0.32)8:0.02,Gi_zeta:0.33)7:0.01,Tv_zeta:0.33)6:0.36,((((Hs_gamma:0.01,Mm_gamma:0.01)16:0.19,Ce_gamma:0.27)15:0.06,(Sc_gamma:0.02,At_gamma:0.00)17:0.26)14:0.31,((((((((((Mm_beta:0.01,Mm_alfa:0.01)26:0.01,Hs_alfa:0.01)25:0.15,Ce_alfa:0.19)24:0.03,At_alfa:0.19)23:0.00,Sc_alfa:0.24)22:0.10,Tv_alfa:0.39)21:0.04,Gi_alfa:0.34)20:0.13,(((((Hs_beta:0.19,Ce_beta:0.17)31:0.02,Sc_beta:0.22)30:0.02,At_beta:0.18)29:0.04,Gi_bet:0.31)28:0.28,(((((Hs_etha:0.01,Mm_etha:0.01)36:0.15,Ce_etha:0.24)35:0.02,At_etha:0.19)34:0.03,Sc_etha:0.25)33:0.05,Tv_etha:0.30)32:0.23)27:0.03)19:0.03,((((((Hs_delta:0.01,Mm_delta:0.01)42:0.18,At_delta:0.22)41:0.01,Sc_delta:0.29)40:0.01,Ce_delta:0.21)39:0.05,Tv_delta:0.34)38:0.20,(((((Mm_epsilon:0.01,Hs_epsilon:0.01)47:0.16,At_epsilon:0.19)46:0.02,Ce_epsilon:0.19)45:0.03,Sc_epsilon:0.29)44:0.02,Gi_epsilon:0.29)43:0.24)37:0.06)18:0.03,((((sulfolobus:0.18,Aeropyruma:0.18)50:0.01,(Aeropytrum2:0.19,Sulfolobus_beta:0.22)51:0.07)49:0.02,(((Methanococ:0.20,Pyrococcusalf:0.17)54:0.03,Archaeoglobus:0.19)53:0.05,thermoplasm:0.28)52:0.04)48:0.03,Haloferax:0.45)0.04)0.02)0.01)1;
end;