ID AGA000066 standard; DNA; INV; 5195 BP.
XX
AC BN000066;
XX
SV BN000066.1
XX
DT 07-OCT-2002 (Rel. 73, Created)
DT 21-NOV-2002 (Rel. 73, Last updated, Version 11)
XX
DE TPA: Anopheles gambiae achE1 gene for acetylcholinesterase, exons 1-6
XX
KW acetylcholinesterase; achE1 gene; Third Party Annotation; TPA.
XX
OS Anopheles gambiae (African malaria mosquito)
OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera;
OC Endopterygota; Diptera; Nematocera; Culicoidea; Anopheles.
XX
RN [1]
RP 1-5195
RA Fort P.P.;
RT ;
RL Submitted (30-NOV-2001) to the EMBL/GenBank/DDBJ databases.
RL Fort P.P., CRBM-UPR1086, Cnrs, 1919 route de Mende, 34293 MONTPELLIER CEDEX
RL 5, FRANCE.
XX
RN [3]
RA Weill M., Fort P., Berthomi eu A., Dubois M.P., Pasteur N., Raymond M.;
RT "A novel acetylcholinesterase gene in mosquitoes codes for the insecticide
RT target and is non-homologous to the ace gene in Drosophila";
RL Proc. R. Soc. Lond., B, Biol. Sci. 269:2007-2016(2002).
XX
CC see also AJ488492 for achE-1 from Kisumu strain
CC Third Party Annotation Database: This TPA record uses Anopheles gambiae
CC trace archive data (http://trace.ensembl.org)
XX
AH TPA_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
AS 1-685 TI55475028 11-685
AS 1-747 TI47553499 11-747
AS 1-800 TI55407518 11-800
AS 188-895 TI57630934 11-707
AS 223-845 TI57283198 11-622
AS 251-895 TI47098900 11-644
AS 272-999 TI56725015 11-727
AS 387-1193 TI57310066 11-806
AS 431-1195 TI56845856 11-764
AS 522-1220 TI55215818 11-698
AS 546-1208 TI57401582 11-661
AS 566-1208 TI56169014 11-642
AS 584-1306 TI59761948 11-722
AS 738-1306 TI55852606 11-568
AS 827-1634 TI57602219 11-807
AS 1064-1769 TI44966390 11-705
AS 1065-1822 TI60742945 11-757
AS 1129-1954 TI56042882 11-825
AS 1223-1979 TI60461178 11-756
AS 1226-1868 TI56472916 11-642
AS 1296-1989 TI44952509 11-693
AS 1364-2170 TI56006358 11-806
AS 1561-2341 TI58704241 11-780
AS 1582-2385 TI44875600 11-803
AS 1740-2415 TI55894404 11-675
AS 1794-2585 TI56056818 11-791
AS 1834-2644 TI47256770 11-809
AS 1848-2729 TI56446066 11-879
AS 1849-2515 TI44984669 11-665
AS 2216-3002 TI57417259 11-786
AS 2224-3029 TI56867244 11-805
AS 2226-3057 TI59803037 11-831
AS 2299-3083 TI60503347 11-784
AS 2614-3351 TI44891398 11-736
AS 2654-3419 TI55336738 11-765
AS 2663-3304 TI60709914 11-641
AS 2672-3417 TI56453591 11-745
AS 2691-3260 TI55690247 11-569
AS 2697-3494 TI55745954 11-797
AS 2885-3706 TI58733608 11-821
AS 2896-3700 TI58130218 11-803
AS 2946-3741 TI56432498 11-795
AS 2992-3702 TI47561255 11-710
AS 2992-3702 TI55208429 11-710
AS 3029-3807 TI47256418 11-778
AS 3030-3831 TI47233061 11-801
AS 3123-3892 TI55870944 11-769
AS 3255-4043 TI47465031 11-787
AS 3325-4045 TI55382589 11-720
AS 3535-4255 TI46993841 11-720
AS 3574-4244 TI56607077 11-670
AS 3596-4394 TI56526265 11-798
AS 3704-4484 TI56050293 11-780
AS 3724-4560 TI59807029 11-836
AS 3745-4549 TI55159438 11-804
AS 3753-4596 TI56586965 11-842
AS 3800-4577 TI56592754 11-777
AS 3833-4635 TI47243257 11-801
AS 3837-4272 TI59628661 11-435
AS 3899-4728 TI56895999 11-829
AS 3938-4704 TI59830483 11-766
AS 3942-4704 TI55700050 11-762
AS 4116-4912 TI56961976 11-796
AS 4137-4761 TI46929238 11-623
AS 4148-4961 TI59909853 11-813
AS 4285-5046 TI47085450 11-759
AS 4315-5069 TI58096045 11-754
AS 4387-5177 TI58084392 11-790
AS 4455-5175 TI55094688 11-720
AS 4455-5195 TI55297322 11-740
AS 4491-5195 TI56990277 11-704
XX
FH Key Location/Qualifiers
FH
FT source 1..5195
FT /db_xref="taxon:7165"
FT /organism="Anopheles gambiae"
FT CDS join(<1780..1914,2001..2538,2618..2815,2902..3609,
FT 3676..3848,3956..4077)
FT /codon_start=3
FT /gene="achE1"
FT /product="acetylcholinesterase"
FT /EC_number="3.1.1.7"
FT /function="hydrolyzes acetylcholine at cholinergic
FT synapses"
FT /protein_id="CAD29865.2"
FT /translation="AFFTPYIGHGESVRIIDAELGTLEHVHSGATPRRRGLTRRESNSD
FT ANDNDPLVVNTDKGRIRGITVDAPSGKKVDVWLGIPYAQPPVGPLRFRHPRPAEKWTGV
FT LNTTTPPNSCVQIVDTVFGDFPGATMWNPNTPLSEDCLYINVVAPRPRPKNAAVMLWIF
FT GGGFYSGTATLDVYDHRALASEENVIVVSLQYRVASLGFLFLGTPEAPGNAGLFDQNLA
FT LRWVRDNIHRFGGDPSRVTLFGESAGAVSVSLHLLSALSRDLFQRAILQSGSPTAPWAL
FT VSREEATLRALRLAEAVGCPHEPSKLSDAVECLRGKDPHVLVNNEWGTLGICEFPFVPV
FT VDGAFLDETPQRSLASGRFKKTEILTGSNTEEGYYFIIYYLTELLRKEEGVTVTREEFL
FT QAVRELNPYVNGAARQAIVFEYTDWTEPDNPNSNRDALDKMVGDYHFTCNVNEFAQRYA
FT EEGNNVYMYLYTHRSKGNPWPRWTGVMHGDEINYVFGEPLNPTLGYTEDEKDFSRKIMR
FT YWSNFAKTGNPNPNTASSEFPEWPKHTAHGRHYLELGLNTSFVGRGPRLRQCAFWKKYL
FT PQLVAATSNLPGPAPPSEPCESSAFFYRPDLIVLLVSLLTATVRFIQ"
FT mRNA join(<1780..1914,2001..2538,2618..2815,2902..3609,
FT 3676..3848,3956..>4596)
FT /gene="achE1"
FT exon <1780..1914
FT /number=1
FT /gene="achE1"
FT intron 1915..2000
FT /number=1
FT /gene="achE1"
FT exon 2001..2538
FT /number=2
FT /gene="achE1"
FT intron 2539..2617
FT /number=2
FT /gene="achE1"
FT exon 2618..2815
FT /number=3
FT /gene="achE1"
FT intron 2816..2901
FT /number=3
FT /gene="achE1"
FT exon 2902..3609
FT /number=4
FT /gene="achE1"
FT intron 3610..3675
FT /number=4
FT /gene="achE1"
FT exon 3676..3848
FT /number=5
FT /gene="achE1"
FT intron 3849..3955
FT /number=5
FT /gene="achE1"
FT exon 3956..>4596
FT /number=6
FT /gene="achE1"
FT polyA_signal 4628..4633
FT /gene="achE1"
XX
SQ Sequence 5195 BP; 1326 A; 1468 C; 1183 G; 1218 T; 0 other;
gaggtggatt ggtacggatt ggtcatttcc gttcttcttc atgtgcgttt cttactctcc 60
tgccttctca aacgaacttc agaacgaaaa aaaacacgcg acggagagta agaagctgta 120
cagacactct agtcctcaca cacacaactt gcttactttg tccgtccgtt tgattccgct 180
ctttctatgt gtgactttct ggcacccttt acttcgtcac tattcatttc atttccaata 240
aacttttaat gtgtctttct tttttattct aaatatctat agtaaatgtt ctgtagcaag 300
tatcttgtag tagaattgta tagaagtaga tttttgtatg agtttgcatc atcccttccc 360
aatggggttg actccgtttc aaccaacgcc aaaagctatc ggcataaagt atggttcctt 420
gcaaaggctt ttatgaaaca cgaatgtgtt gaaagctttt gcaaatggaa atgttaaagc 480
ctttaagttc caatcgcttt ttgtatccat ttagtttgca tgaacaacag gaaatcaaaa 540
tattggtaac gacaatcgct ggcgggcgtt cctttcttgt ctaatcaaat catctacgat 600
tgtaattaca aacttccaag tttgcgtatg acaatgttaa atgtctaaga cgctcaaatg 660
caaccaatag agtataatta ctaaggcggg cagtagaaac caaaatatct taaataatgt 720
caagcaaaac aaaaagaaca attccgttca ctgctcaaag aaagccctaa ctaactacct 780
aaccttttca tcgatgaccc tgtactgaca tggtaagata ttctttatcc tttaactctt 840
ctgcacccta cgcactcaat gcaacacacg cactactatt actgctacta ctctcgcact 900
cacgagcacc tacttgcact caagccggca ctcaatgtac tagcgaaaca cgtcgcatct 960
aagcactcac aaggaagcac acatttgcaa atagcaccta ccggaacagc tttgaatgtg 1020
ccagcacagc attgaacagg ttcgcgcctt tactcctgtg ctctgttttc tcgatcggaa 1080
tgttcgaaag ttgaaaagcg cattttttca tctctctttt tctattcttc ttcgtatttt 1140
tatccctctc tcgtcgtgtt ttttctaaac attaccatac ttcttccgct acgaactcgc 1200
caagaaccag aacgcagcgt gcgtgcggtg cttgcggtgt gtgtgtgtgt gtgtgtattc 1260
cacggctgcg agaagcaaga tcggagaaca ggcatcattc ccctttcaca gacaattgca 1320
cttttgtact agaacagaaa acgagacagc ataatttcca acagcctcat tcactcatac 1380
caggctcaca ccgactttta accgaaacat gtactacaga aacaaaaaca aacaatatgg 1440
agagtgctcg cgctgatact aagttaatat gaagagatta ctggcgaggt catcgatccc 1500
atcccgacat catcgctcca ggctccagac ctaccaagtc gcctaccatt acctacccac 1560
caccgaccac tactcacaca gcattatcac ttccgccgcc gtcgccgccg ccgccgacgc 1620
cgccgacgcc accaccttca caccgccctg ccaaaatgaa tgcgcattgt tgcgatagat 1680
tgaatttcct tggttgttgt tgttgttggt tttcttttga catgtttgtg tgttgttttt 1740
tctttctctc tctctctttc tgtggttcca acatttcaga cgcatttttt acaccatata 1800
taggtcacgg tgagtccgta cgaattatag atgccgagtt gggcacgctc gagcatgtcc 1860
acagtggagc aacgccgcgg cgacgcggcc tgacgaggcg cgagtcaaac tcgggtaagt 1920
acgcgattgg aagtgggggg acgtttaccc taccgtgtac tactacaacg cactttaccc 1980
ccacgcacac gcaccggcag acgcgaacga caacgatccg ctggtggtca acacggataa 2040
ggggcgcatc cgcggcatta cggtcgatgc gcccagcggc aagaaggtgg acgtgtggct 2100
cggcattccc tacgcccagc cgccggtcgg gccgctacgg ttccgtcatc cgcggccggc 2160
cgaaaagtgg accggcgtgc tgaacacgac cacaccgccc aacagctgcg tgcagatcgt 2220
ggacaccgtg ttcggcgact tcccgggcgc gaccatgtgg aacccgaaca cgcccctgtc 2280
cgaggactgt ctgtacatta acgtggtggc accgcgaccc cggcccaaga atgcggccgt 2340
catgctgtgg atcttcggcg gcggcttcta ctccggcacc gccaccctgg acgtgtacga 2400
ccaccgggcg cttgcgtcgg aggagaacgt gatcgtggtg tcgctgcagt accgcgtggc 2460
cagtctgggc ttcctgtttc tcggcacccc ggaagcgccg ggcaatgcgg gactgttcga 2520
tcagaacctt gcgctacggt aggtgtcttt gcatgtgtga atgagggtat agtattctaa 2580
cgaggtgctc ttcttcccat cacttcttgg gagtcagctg ggtgcgggac aacattcacc 2640
ggttcggtgg cgatccgtcg cgtgtgacac tgttcggcga gagtgccggt gccgtctcgg 2700
tgtcgctgca tctgctgtcc gccctttccc gcgatctgtt ccagcgggcc atcctgcaga 2760
gcggctcgcc gacggcaccg tgggcattgg tatcgcgcga ggaagccaca ctaaggtacg 2820
tgccagctgc tgctttcccc aaaccaccaa cccgcaacag ctcacacaac cctcttttcc 2880
gtcgctcttt tctcgctcca gagcactgcg gttggccgag gcggtcggct gcccgcacga 2940
accgagcaag ctgagcgatg cggtcgagtg cctgcgcggc aaggacccgc acgtgctggt 3000
caacaacgag tggggcacgc tcggcatttg cgagttcccg ttcgtgccgg tggtcgacgg 3060
tgcgttcctg gacgagacgc cgcagcgttc gctcgccagc gggcgcttca agaagacgga 3120
gatcctcacc ggcagcaaca cggaggaggg ctactacttc atcatctact acctgaccga 3180
gctgctgcgc aaggaggagg gcgtgaccgt gacgcgcgag gagttcctgc aggcggtgcg 3240
cgagctcaac ccgtacgtga acggggcggc ccggcaggcg atcgtgttcg agtacaccga 3300
ctggaccgag ccggacaacc cgaacagcaa ccgggacgcg ctggacaaga tggtgggcga 3360
ctatcacttc acctgcaacg tgaacgagtt cgcgcagcgg tacgccgagg agggcaacaa 3420
cgtctacatg tatctgtaca cgcaccgcag caaaggcaac ccgtggccgc gctggacggg 3480
cgtgatgcac ggcgacgaga tcaactacgt gttcggcgaa ccgctcaacc ccaccctcgg 3540
ctacaccgag gacgagaaag actttagccg gaagatcatg cgatactggt ccaactttgc 3600
caaaaccggg taagtgtgtg tgtcaaacag cagagtgtcg atcgctctaa caccagcgtc 3660
ttctctcttc tacagcaatc caaatcccaa cacggccagc agcgaattcc ccgagtggcc 3720
caagcacacc gcccacggac ggcactatct ggagctgggc ctcaacacgt ccttcgtcgg 3780
tcggggccca cggttgaggc agtgtgcctt ctggaagaag taccttcccc agctagttgc 3840
agctacctgt aagtctcgtg cagcacttga aaccccctcc cacatcccca tcagggtcca 3900
ggttgcaata ataaatttca ctttctctct ctcacgtctc ttttccccaa aacagcgaac 3960
ctaccagggc cagcaccgcc tagtgaaccg tgcgaaagca gcgcattttt ttaccgacct 4020
gatctgatcg tgctgctggt gtcgctgctt acggcgaccg tcagattcat acaataatta 4080
ctaccccatc catggcctag ttcgtttaag ctttaagata gtgaggaaca aatttttccc 4140
aaacaatttt ccccccttta gagcagaacc gagggagaga taggactaca tagcgaaaag 4200
ggaaaacaag tggtggcgga cgaggagaga agaagcaaat cgaataatcg aagcaacaac 4260
aacaacaaca aaaaaactgc aaccgggttc actaaaccca gggggcagct cagtagcaaa 4320
ctactactta aataactact ttcttatggc aaattatggc aagagcagtc gtgatgggtt 4380
cgatcagtat ccatctgacc ggagcagctg aaccgtttca tgggcagttg ctgcaataca 4440
ccacgacccg tacacacagt aacacacttt ttatagcttt acactaacaa ccactctccc 4500
cacgctcctc ttccccttcc cctccacaca gacagcagcg ccgtttgtag caggatctac 4560
taccgtgcgg tttggtatgg cggccaacaa cactaaacac cacacatcta ctaaaacaca 4620
ccggaacaat aaacaaatgt taaacttact atatgaatat acatctagac gcatatatac 4680
gcatgaacta ctacttccct cgtgttctga caaaacacat taccttgtcc cccctccccc 4740
tccggtttgc ttaccaccac tgcaccacca gtatgaattt gttccataat aacgcttcgt 4800
aactcgttac caggagcaca actgggtcgt tggcggagtg ctgcgcgttt cgtgctgaag 4860
atgtaaacta gcaccgcgca cactttcgac acgcaaccac agctacacat cacgaaagca 4920
acatcctggc cctatccgtt ttctcattct taaaacttct ttccttagac caaaaccaac 4980
gcaaactagc aaaaggtact tgagtaaccg gtccagtaca cactgtgcta caattgagcg 5040
tagggaggag gtataatttc tgcaaaatgt ataaaacaaa actaaaacaa actaattact 5100
tgcaatccat tctaaagcac gaaaactcct caaaataaaa acgggaagta aacaaaaaaa 5160
tcagaacgaa caaatttacc taaaaaaaag taaac 5195
//