Entrezgene ::= {
track-info {
geneid 3581,
status live,
create-date std {
year 1997,
month 11,
day 18
},
update-date std {
year 2013,
month 12,
day 8,
hour 11,
minute 11,
second 0
}
},
type protein-coding,
source {
genome genomic,
origin natural,
org {
taxname "Homo sapiens",
common "human",
db {
{
db "taxon",
tag id 9606
}
},
syn {
"man"
},
orgname {
name binomial {
genus "Homo",
species "sapiens"
},
lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo",
gcode 1,
mgcode 2,
div "PRI",
pgcode 0
}
},
subtype {
{
subtype chromosome,
name "X"
},
{
subtype chromosome,
name "Y"
}
}
},
gene {
locus "IL9R",
desc "interleukin 9 receptor",
maploc "Xq28 and Yq12",
db {
{
db "HGNC",
tag id 6030
},
{
db "Ensembl",
tag str "ENSG00000124334"
},
{
db "HPRD",
tag str "02052"
},
{
db "MIM",
tag id 300007
},
{
db "Vega",
tag str "OTTHUMG00000022720"
}
},
syn {
"CD129",
"IL-9R"
}
},
prot {
name {
"interleukin-9 receptor",
"IL-9 receptor"
},
desc "interleukin-9 receptor"
},
summary "The protein encoded by this gene is a cytokine receptor that
specifically mediates the biological effects of interleukin 9 (IL9). The
functional IL9 receptor complex requires this protein as well as the
interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the
receptors of many different cytokines. The ligand binding of this receptor
leads to the activation of various JAK kinases and STAT proteins, which
connect to different biologic responses. This gene is located at the
pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an
association of this gene with the development of asthma. Multiple pseudogenes
on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced
transcript variants have been found for this gene. [provided by RefSeq, Jul
2008]",
location {
{
display-str "Xq28 and Yq12",
method map-type cyto
}
},
gene-source {
src "LocusLink",
src-int 3581,
src-str2 "3581"
},
locus {
{
type genomic,
heading "Reference GRCh37.p13 Primary Assembly",
label "chromosome Y reference GRCh37.p13 Primary Assembly",
accession "NC_000024",
version 9,
seqs {
int {
from 59330251,
to 59343487,
strand plus,
id gi 224589823
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 2",
accession "NM_176786",
version 1,
genomic-coords {
mix {
int {
from 59330251,
to 59330457,
strand plus,
id gi 224589823
},
int {
from 59334078,
to 59334178,
strand plus,
id gi 224589823
},
int {
from 59335552,
to 59335689,
strand plus,
id gi 224589823
},
int {
from 59336119,
to 59336230,
strand plus,
id gi 224589823
},
int {
from 59336354,
to 59336525,
strand plus,
id gi 224589823
},
int {
from 59337119,
to 59337235,
strand plus,
id gi 224589823
},
int {
from 59337948,
to 59338149,
strand plus,
id gi 224589823
},
int {
from 59338753,
to 59338858,
strand plus,
id gi 224589823
},
int {
from 59342486,
to 59343487,
strand plus,
id gi 224589823
}
}
},
seqs {
whole gi 29171683
},
products {
{
type peptide,
heading "Reference",
label "isoform 2",
accession "NP_789743",
version 2,
source {
{
src {
db "CCDS",
tag str "CCDS59180.1"
},
anchor "CCDS59180.1"
}
},
genomic-coords {
mix {
int {
from 59330414,
to 59330457,
strand plus,
id gi 224589823
},
int {
from 59334078,
to 59334178,
strand plus,
id gi 224589823
},
int {
from 59335552,
to 59335689,
strand plus,
id gi 224589823
},
int {
from 59336119,
to 59336230,
strand plus,
id gi 224589823
},
int {
from 59336354,
to 59336525,
strand plus,
id gi 224589823
},
int {
from 59337119,
to 59337235,
strand plus,
id gi 224589823
},
int {
from 59337948,
to 59338149,
strand plus,
id gi 224589823
},
int {
from 59338753,
to 59338858,
strand plus,
id gi 224589823
},
int {
from 59342486,
to 59342522,
strand plus,
id gi 224589823
}
}
},
seqs {
whole gi 388490122
}
}
}
},
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_002186",
version 2,
genomic-coords {
mix {
int {
from 59330251,
to 59330457,
strand plus,
id gi 224589823
},
int {
from 59335576,
to 59335689,
strand plus,
id gi 224589823
},
int {
from 59336119,
to 59336230,
strand plus,
id gi 224589823
},
int {
from 59336347,
to 59336525,
strand plus,
id gi 224589823
},
int {
from 59337090,
to 59337235,
strand plus,
id gi 224589823
},
int {
from 59337948,
to 59338149,
strand plus,
id gi 224589823
},
int {
from 59338753,
to 59338858,
strand plus,
id gi 224589823
},
int {
from 59340193,
to 59340277,
strand plus,
id gi 224589823
},
int {
from 59342486,
to 59343487,
strand plus,
id gi 224589823
}
}
},
seqs {
whole gi 29171681
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_002177",
version 2,
source {
{
src {
db "CCDS",
tag str "CCDS14771.4"
},
anchor "CCDS14771.4"
}
},
genomic-coords {
mix {
int {
from 59330430,
to 59330457,
strand plus,
id gi 224589823
},
int {
from 59335576,
to 59335689,
strand plus,
id gi 224589823
},
int {
from 59336119,
to 59336230,
strand plus,
id gi 224589823
},
int {
from 59336347,
to 59336525,
strand plus,
id gi 224589823
},
int {
from 59337090,
to 59337235,
strand plus,
id gi 224589823
},
int {
from 59337948,
to 59338149,
strand plus,
id gi 224589823
},
int {
from 59338753,
to 59338858,
strand plus,
id gi 224589823
},
int {
from 59340193,
to 59340277,
strand plus,
id gi 224589823
},
int {
from 59342486,
to 59343079,
strand plus,
id gi 224589823
}
}
},
seqs {
whole gi 29171682
}
}
}
}
}
},
{
type genomic,
heading "Reference GRCh37.p13 Primary Assembly",
label "chromosome X reference GRCh37.p13 Primary Assembly",
accession "NC_000023",
version 10,
seqs {
int {
from 155227245,
to 155240481,
strand plus,
id gi 224589822
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 2",
accession "NM_176786",
version 1,
genomic-coords {
mix {
int {
from 155227245,
to 155227451,
strand plus,
id gi 224589822
},
int {
from 155231072,
to 155231172,
strand plus,
id gi 224589822
},
int {
from 155232546,
to 155232683,
strand plus,
id gi 224589822
},
int {
from 155233113,
to 155233224,
strand plus,
id gi 224589822
},
int {
from 155233348,
to 155233519,
strand plus,
id gi 224589822
},
int {
from 155234113,
to 155234229,
strand plus,
id gi 224589822
},
int {
from 155234942,
to 155235143,
strand plus,
id gi 224589822
},
int {
from 155235747,
to 155235852,
strand plus,
id gi 224589822
},
int {
from 155239480,
to 155240481,
strand plus,
id gi 224589822
}
}
},
seqs {
whole gi 29171683
},
products {
{
type peptide,
heading "Reference",
label "isoform 2",
accession "NP_789743",
version 2,
source {
{
src {
db "CCDS",
tag str "CCDS59180.1"
},
anchor "CCDS59180.1"
}
},
genomic-coords {
mix {
int {
from 155227408,
to 155227451,
strand plus,
id gi 224589822
},
int {
from 155231072,
to 155231172,
strand plus,
id gi 224589822
},
int {
from 155232546,
to 155232683,
strand plus,
id gi 224589822
},
int {
from 155233113,
to 155233224,
strand plus,
id gi 224589822
},
int {
from 155233348,
to 155233519,
strand plus,
id gi 224589822
},
int {
from 155234113,
to 155234229,
strand plus,
id gi 224589822
},
int {
from 155234942,
to 155235143,
strand plus,
id gi 224589822
},
int {
from 155235747,
to 155235852,
strand plus,
id gi 224589822
},
int {
from 155239480,
to 155239516,
strand plus,
id gi 224589822
}
}
},
seqs {
whole gi 388490122
}
}
}
},
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_002186",
version 2,
genomic-coords {
mix {
int {
from 155227245,
to 155227451,
strand plus,
id gi 224589822
},
int {
from 155232570,
to 155232683,
strand plus,
id gi 224589822
},
int {
from 155233113,
to 155233224,
strand plus,
id gi 224589822
},
int {
from 155233341,
to 155233519,
strand plus,
id gi 224589822
},
int {
from 155234084,
to 155234229,
strand plus,
id gi 224589822
},
int {
from 155234942,
to 155235143,
strand plus,
id gi 224589822
},
int {
from 155235747,
to 155235852,
strand plus,
id gi 224589822
},
int {
from 155237187,
to 155237271,
strand plus,
id gi 224589822
},
int {
from 155239480,
to 155240481,
strand plus,
id gi 224589822
}
}
},
seqs {
whole gi 29171681
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_002177",
version 2,
source {
{
src {
db "CCDS",
tag str "CCDS14771.4"
},
anchor "CCDS14771.4"
}
},
genomic-coords {
mix {
int {
from 155227424,
to 155227451,
strand plus,
id gi 224589822
},
int {
from 155232570,
to 155232683,
strand plus,
id gi 224589822
},
int {
from 155233113,
to 155233224,
strand plus,
id gi 224589822
},
int {
from 155233341,
to 155233519,
strand plus,
id gi 224589822
},
int {
from 155234084,
to 155234229,
strand plus,
id gi 224589822
},
int {
from 155234942,
to 155235143,
strand plus,
id gi 224589822
},
int {
from 155235747,
to 155235852,
strand plus,
id gi 224589822
},
int {
from 155237187,
to 155237271,
strand plus,
id gi 224589822
},
int {
from 155239480,
to 155240073,
strand plus,
id gi 224589822
}
}
},
seqs {
whole gi 29171682
}
}
}
}
}
},
{
type genomic,
heading "Reference assembly",
label "RefSeqGene",
accession "NG_013238",
version 1,
seqs {
int {
from 5000,
to 18236,
strand plus,
id gi 261823945
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_002186",
version 2,
genomic-coords {
mix {
int {
from 5000,
to 5206,
strand plus,
id gi 261823945
},
int {
from 10325,
to 10438,
strand plus,
id gi 261823945
},
int {
from 10868,
to 10979,
strand plus,
id gi 261823945
},
int {
from 11096,
to 11274,
strand plus,
id gi 261823945
},
int {
from 11839,
to 11984,
strand plus,
id gi 261823945
},
int {
from 12697,
to 12898,
strand plus,
id gi 261823945
},
int {
from 13502,
to 13607,
strand plus,
id gi 261823945
},
int {
from 14942,
to 15026,
strand plus,
id gi 261823945
},
int {
from 17235,
to 18236,
strand plus,
id gi 261823945
}
}
},
seqs {
whole gi 29171681
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_002177",
version 2,
source {
{
src {
db "CCDS",
tag str "CCDS14771.4"
},
anchor "CCDS14771.4"
}
},
genomic-coords {
mix {
int {
from 5179,
to 5206,
strand plus,
id gi 261823945
},
int {
from 10325,
to 10438,
strand plus,
id gi 261823945
},
int {
from 10868,
to 10979,
strand plus,
id gi 261823945
},
int {
from 11096,
to 11274,
strand plus,
id gi 261823945
},
int {
from 11839,
to 11984,
strand plus,
id gi 261823945
},
int {
from 12697,
to 12898,
strand plus,
id gi 261823945
},
int {
from 13502,
to 13607,
strand plus,
id gi 261823945
},
int {
from 14942,
to 15026,
strand plus,
id gi 261823945
},
int {
from 17235,
to 17828,
strand plus,
id gi 261823945
}
}
},
seqs {
whole gi 29171682
}
}
}
}
}
},
{
type genomic,
heading "Alternate CHM1_1.1",
label "chromosome X alternate CHM1_1.1",
accession "NC_018934",
version 2,
seqs {
int {
from 155138862,
to 155152088,
strand plus,
id gi 528476524
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 2",
accession "NM_176786",
version 1,
genomic-coords {
mix {
int {
from 155138862,
to 155139068,
strand plus,
id gi 528476524
},
int {
from 155142688,
to 155142788,
strand plus,
id gi 528476524
},
int {
from 155144166,
to 155144303,
strand plus,
id gi 528476524
},
int {
from 155144733,
to 155144844,
strand plus,
id gi 528476524
},
int {
from 155144968,
to 155145139,
strand plus,
id gi 528476524
},
int {
from 155145733,
to 155145849,
strand plus,
id gi 528476524
},
int {
from 155146562,
to 155146763,
strand plus,
id gi 528476524
},
int {
from 155147367,
to 155147472,
strand plus,
id gi 528476524
},
int {
from 155151087,
to 155152088,
strand plus,
id gi 528476524
}
}
},
seqs {
whole gi 29171683
},
products {
{
type peptide,
heading "Reference",
label "isoform 2",
accession "NP_789743",
version 2,
genomic-coords {
mix {
int {
from 155139025,
to 155139068,
strand plus,
id gi 528476524
},
int {
from 155142688,
to 155142788,
strand plus,
id gi 528476524
},
int {
from 155144166,
to 155144303,
strand plus,
id gi 528476524
},
int {
from 155144733,
to 155144844,
strand plus,
id gi 528476524
},
int {
from 155144968,
to 155145139,
strand plus,
id gi 528476524
},
int {
from 155145733,
to 155145849,
strand plus,
id gi 528476524
},
int {
from 155146562,
to 155146763,
strand plus,
id gi 528476524
},
int {
from 155147367,
to 155147472,
strand plus,
id gi 528476524
},
int {
from 155151087,
to 155151123,
strand plus,
id gi 528476524
}
}
},
seqs {
whole gi 388490122
}
}
}
},
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_002186",
version 2,
genomic-coords {
mix {
int {
from 155138862,
to 155139068,
strand plus,
id gi 528476524
},
int {
from 155144190,
to 155144303,
strand plus,
id gi 528476524
},
int {
from 155144733,
to 155144844,
strand plus,
id gi 528476524
},
int {
from 155144961,
to 155145139,
strand plus,
id gi 528476524
},
int {
from 155145704,
to 155145849,
strand plus,
id gi 528476524
},
int {
from 155146562,
to 155146763,
strand plus,
id gi 528476524
},
int {
from 155147367,
to 155147472,
strand plus,
id gi 528476524
},
int {
from 155148808,
to 155148892,
strand plus,
id gi 528476524
},
int {
from 155151087,
to 155152088,
strand plus,
id gi 528476524
}
}
},
seqs {
whole gi 29171681
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_002177",
version 2,
genomic-coords {
mix {
int {
from 155139041,
to 155139068,
strand plus,
id gi 528476524
},
int {
from 155144190,
to 155144303,
strand plus,
id gi 528476524
},
int {
from 155144733,
to 155144844,
strand plus,
id gi 528476524
},
int {
from 155144961,
to 155145139,
strand plus,
id gi 528476524
},
int {
from 155145704,
to 155145849,
strand plus,
id gi 528476524
},
int {
from 155146562,
to 155146763,
strand plus,
id gi 528476524
},
int {
from 155147367,
to 155147472,
strand plus,
id gi 528476524
},
int {
from 155148808,
to 155148892,
strand plus,
id gi 528476524
},
int {
from 155151087,
to 155151680,
strand plus,
id gi 528476524
}
}
},
seqs {
whole gi 29171682
}
}
}
}
}
},
{
type genomic,
heading "Alternate HuRef",
label "chromosome X alternate HuRef",
accession "AC_000155",
version 1,
seqs {
int {
from 143710175,
to 143723406,
strand plus,
id gi 157734237
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 2",
accession "NM_176786",
version 1,
genomic-coords {
mix {
int {
from 143710175,
to 143710381,
strand plus,
id gi 157734237
},
int {
from 143714002,
to 143714102,
strand plus,
id gi 157734237
},
int {
from 143715480,
to 143715617,
strand plus,
id gi 157734237
},
int {
from 143716047,
to 143716158,
strand plus,
id gi 157734237
},
int {
from 143716282,
to 143716453,
strand plus,
id gi 157734237
},
int {
from 143717047,
to 143717163,
strand plus,
id gi 157734237
},
int {
from 143717876,
to 143718077,
strand plus,
id gi 157734237
},
int {
from 143718681,
to 143718786,
strand plus,
id gi 157734237
},
int {
from 143722405,
to 143723406,
strand plus,
id gi 157734237
}
}
},
seqs {
whole gi 29171683
},
products {
{
type peptide,
heading "Reference",
label "isoform 2",
accession "NP_789743",
version 2,
genomic-coords {
mix {
int {
from 143710338,
to 143710381,
strand plus,
id gi 157734237
},
int {
from 143714002,
to 143714102,
strand plus,
id gi 157734237
},
int {
from 143715480,
to 143715617,
strand plus,
id gi 157734237
},
int {
from 143716047,
to 143716158,
strand plus,
id gi 157734237
},
int {
from 143716282,
to 143716453,
strand plus,
id gi 157734237
},
int {
from 143717047,
to 143717163,
strand plus,
id gi 157734237
},
int {
from 143717876,
to 143718077,
strand plus,
id gi 157734237
},
int {
from 143718681,
to 143718786,
strand plus,
id gi 157734237
},
int {
from 143722405,
to 143722441,
strand plus,
id gi 157734237
}
}
},
seqs {
whole gi 388490122
}
}
}
},
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_002186",
version 2,
genomic-coords {
mix {
int {
from 143710175,
to 143710381,
strand plus,
id gi 157734237
},
int {
from 143715504,
to 143715617,
strand plus,
id gi 157734237
},
int {
from 143716047,
to 143716158,
strand plus,
id gi 157734237
},
int {
from 143716275,
to 143716453,
strand plus,
id gi 157734237
},
int {
from 143717018,
to 143717163,
strand plus,
id gi 157734237
},
int {
from 143717876,
to 143718077,
strand plus,
id gi 157734237
},
int {
from 143718681,
to 143718786,
strand plus,
id gi 157734237
},
int {
from 143720118,
to 143720202,
strand plus,
id gi 157734237
},
int {
from 143722405,
to 143723406,
strand plus,
id gi 157734237
}
}
},
seqs {
whole gi 29171681
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_002177",
version 2,
genomic-coords {
mix {
int {
from 143710354,
to 143710381,
strand plus,
id gi 157734237
},
int {
from 143715504,
to 143715617,
strand plus,
id gi 157734237
},
int {
from 143716047,
to 143716158,
strand plus,
id gi 157734237
},
int {
from 143716275,
to 143716453,
strand plus,
id gi 157734237
},
int {
from 143717018,
to 143717163,
strand plus,
id gi 157734237
},
int {
from 143717876,
to 143718077,
strand plus,
id gi 157734237
},
int {
from 143718681,
to 143718786,
strand plus,
id gi 157734237
},
int {
from 143720118,
to 143720202,
strand plus,
id gi 157734237
},
int {
from 143722405,
to 143722998,
strand plus,
id gi 157734237
}
}
},
seqs {
whole gi 29171682
}
}
}
}
}
}
},
properties {
{
type comment,
label "Nomenclature",
source {
{
anchor "HUGO Gene Nomenclature Committee"
}
},
properties {
{
type property,
label "Official Symbol",
text "IL9R"
},
{
type property,
label "Official Full Name",
text "interleukin 9 receptor"
}
}
},
{
type comment,
heading "GeneOntology",
source {
{
pre-text "Provided by",
anchor "GOA",
url "http://www.ebi.ac.uk/GOA/"
}
},
comment {
{
type comment,
label "Function",
comment {
{
type comment,
refs {
pmid 1376929
},
source {
{
src {
db "GO",
tag id 4919
},
anchor "interleukin-9 receptor activity",
post-text "evidence: TAS"
}
}
}
}
},
{
type comment,
label "Process",
comment {
{
type comment,
refs {
pmid 1376929
},
source {
{
src {
db "GO",
tag id 8283
},
anchor "cell proliferation",
post-text "evidence: TAS"
}
}
},
{
type comment,
refs {
pmid 1376929
},
source {
{
src {
db "GO",
tag id 38113
},
anchor "interleukin-9-mediated signaling pathway",
post-text "evidence: TAS"
}
}
},
{
type comment,
refs {
pmid 1376929
},
source {
{
src {
db "GO",
tag id 7165
},
anchor "signal transduction",
post-text "evidence: TAS"
}
}
}
}
},
{
type comment,
label "Component",
comment {
{
type comment,
refs {
pmid 1376929
},
source {
{
src {
db "GO",
tag id 5615
},
anchor "extracellular space",
post-text "evidence: TAS"
}
}
},
{
type comment,
refs {
pmid 1376929
},
source {
{
src {
db "GO",
tag id 5887
},
anchor "integral to plasma membrane",
post-text "evidence: TAS"
}
}
}
}
}
}
}
},
homology {
{
type comment,
heading "Mouse, Rat",
source {
{
src {
db "HomoloGene",
tag id 37591
},
anchor "Map Viewer",
url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=X&M
APS=genes-r-org/rat-chr/human%3AX,genes-r-org/mouse-chr/human%3AX,genes-r-org/
human-chrX&query=e%3A3581[egene_id]+AND+gene[obj_type]&QSTR=il9r&cmd=focus&fil
l=10",
post-text "(chromosome X)"
}
}
},
{
type comment,
heading "Mouse, Rat",
source {
{
src {
db "HomoloGene",
tag id 37591
},
anchor "Map Viewer",
url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=Y&M
APS=genes-r-org/rat-chr/human%3AY,genes-r-org/mouse-chr/human%3AY,genes-r-org/
human-chrY&query=e%3A3581[egene_id]+AND+gene[obj_type]&QSTR=il9r&cmd=focus&fil
l=10",
post-text "(chromosome Y)"
}
}
}
},
comments {
{
type comment,
heading "RefSeq Status",
label "REVIEWED"
},
{
type comment,
heading "Annotation Information",
properties {
{
type property,
label "Annotation category",
text "partial on reference assembly"
}
}
},
{
type gene-group,
heading "Related pseudogene(s)",
source {
{
pre-text "5 found",
anchor "Review record(s) in Gene"
}
}
},
{
type comment,
refs {
pmid 23638223,
pmid 22638550,
pmid 21371865,
pmid 20673868,
pmid 20595916,
pmid 20503287,
pmid 20452482,
pmid 20424473,
pmid 19723899,
pmid 19692168,
pmid 19401191,
pmid 19258923,
pmid 19139102,
pmid 18829468,
pmid 18633131,
pmid 18339896,
pmid 17919707,
pmid 17703412,
pmid 17207965,
pmid 17192395,
pmid 17083349,
pmid 15621723,
pmid 15591265,
pmid 12477932,
pmid 11868823,
pmid 11588013,
pmid 11418623,
pmid 11160343,
pmid 11039580,
pmid 10657622,
pmid 10655549,
pmid 10642536,
pmid 10486269,
pmid 10329852,
pmid 9535918,
pmid 9002663,
pmid 8756628,
pmid 8666384,
pmid 8193355,
pmid 7718508,
pmid 1376929
}
},
{
type comment,
heading "NCBI Reference Sequences (RefSeq)",
comment {
{
type comment,
heading "RefSeqs maintained independently of Annotated Genomes",
products {
{
type mRNA,
heading "mRNA Sequence",
accession "NM_002186",
version 2,
source {
{
src {
db "Nucleotide",
tag id 29171681
},
anchor "NM_002186"
}
},
seqs {
whole gi 29171681
},
products {
{
type peptide,
heading "Product",
accession "NP_002177",
version 2,
source {
{
src {
db "Protein",
tag id 29171682
},
anchor "NP_002177",
post-text "interleukin-9 receptor isoform 1 precursor"
}
},
seqs {
whole gi 29171682
},
comment {
{
type other,
heading "Related",
source {
{
src {
db "Ensembl",
tag str "ENSP00000244174"
}
}
}
},
{
type other,
heading "UniProtKB",
source {
},
comment {
{
type other,
source {
{
src {
db "UniProtKB/Swiss-Prot",
tag str "Q01113"
},
anchor "Q01113"
}
}
}
}
},
{
type other,
heading "Consensus CDS (CCDS)",
source {
{
src {
db "CCDS",
tag str "CCDS14771.4"
},
anchor "CCDS14771.4"
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Vega",
tag str "OTTHUMP00000024332"
}
}
}
}
}
}
},
comment {
{
type comment,
label "RefSeq Status",
text "REVIEWED"
},
{
type comment,
heading "Transcriptional Variant",
comment {
{
type comment,
text "Transcript Variant: This variant (1) represent the
longer transcript and encodes the longer isoform (1)."
}
}
},
{
type other,
heading "Source Sequence",
source {
{
src {
db "Nucleotide",
tag str "BC025298,M84747"
},
anchor "BC025298,M84747"
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Ensembl",
tag str "ENST00000244174"
}
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Vega",
tag str "OTTHUMT00000058981"
}
}
}
}
}
},
{
type mRNA,
heading "mRNA Sequence",
accession "NM_176786",
version 1,
source {
{
src {
db "Nucleotide",
tag id 29171683
},
anchor "NM_176786"
}
},
seqs {
whole gi 29171683
},
products {
{
type peptide,
heading "Product",
accession "NP_789743",
version 2,
source {
{
src {
db "Protein",
tag id 388490122
},
anchor "NP_789743",
post-text "interleukin-9 receptor isoform 2"
}
},
seqs {
whole gi 388490122
},
comment {
{
type other,
heading "Related",
source {
{
src {
db "Ensembl",
tag str "ENSP00000358431"
}
}
}
},
{
type other,
heading "UniProtKB",
source {
},
comment {
{
type other,
source {
{
src {
db "UniProtKB/Swiss-Prot",
tag str "Q01113"
},
anchor "Q01113"
}
}
}
}
},
{
type other,
heading "Consensus CDS (CCDS)",
source {
{
src {
db "CCDS",
tag str "CCDS59180.1"
},
anchor "CCDS59180.1"
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Vega",
tag str "OTTHUMP00000024331"
}
}
}
}
}
}
},
comment {
{
type comment,
label "RefSeq Status",
text "REVIEWED"
},
{
type comment,
heading "Transcriptional Variant",
comment {
{
type comment,
text "Transcript Variant: This variant (2) differs in
the 5' and 3' UTR and has multiple coding region differences, compared to
variant 1. Some of these differences result in translational frameshifts. The
resulting isoform (2) has distinct N- and C-termini and is shorter than
isoform 1."
}
}
},
{
type other,
heading "Source Sequence",
source {
{
src {
db "Nucleotide",
tag str "AJ271736,BC025298"
},
anchor "AJ271736,BC025298"
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Ensembl",
tag str "ENST00000369423"
}
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Vega",
tag str "OTTHUMT00000058980"
}
}
}
}
}
}
},
comment {
{
type genomic,
heading "RefSeqGene",
accession "NG_013238",
version 1,
source {
{
src {
db "Nucleotide",
tag id 261823945
},
anchor "NG_013238"
}
},
seqs {
int {
from 5000,
to 18236,
strand plus,
id gi 261823945
}
}
}
}
},
{
type comment,
heading "RefSeqs of Annotated Genomes: Homo sapiens Annotation
Release 105",
products {
{
type genomic,
heading "Reference GRCh37.p13 Primary Assembly",
accession "NC_000023",
version 10,
source {
{
src {
db "Nucleotide",
tag id 224589822
}
}
},
seqs {
int {
from 155227245,
to 155240481,
strand plus,
id gi 224589822
}
}
},
{
type genomic,
heading "Alternate HuRef",
accession "AC_000155",
version 1,
source {
{
src {
db "Nucleotide",
tag id 157734237
}
}
},
seqs {
int {
from 143710175,
to 143723406,
strand plus,
id gi 157734237
}
}
},
{
type genomic,
heading "Alternate CHM1_1.1",
accession "NC_018934",
version 2,
source {
{
src {
db "Nucleotide",
tag id 528476524
}
}
},
seqs {
int {
from 155138862,
to 155152088,
strand plus,
id gi 528476524
}
}
}
}
}
}
},
{
type comment,
heading "Related Sequences",
products {
{
type genomic,
heading "Genomic",
accession "ABBA01028635",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148163528
},
anchor "ABBA01028635"
}
},
seqs {
int {
from 28050,
to 41281,
strand plus,
id gi 148163528
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AJ271736",
version 1,
source {
{
src {
db "Nucleotide",
tag id 8979791
},
anchor "AJ271736"
}
},
seqs {
whole gi 8979791
},
products {
{
type peptide,
accession "CAB96817",
version 1,
source {
{
src {
db "Protein",
tag id 8979793
},
anchor "CAB96817"
}
},
seqs {
whole gi 8979793
}
}
}
},
{
type genomic,
heading "Genomic",
accession "AMYH02040904",
version 1,
source {
{
src {
db "Nucleotide",
tag id 511784226
},
anchor "AMYH02040904"
}
},
seqs {
int {
from 17496,
to 30722,
strand plus,
id gi 511784226
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AY071830",
version 1,
source {
{
src {
db "Nucleotide",
tag id 18071671
},
anchor "AY071830"
}
},
seqs {
whole gi 18071671
},
products {
{
type peptide,
accession "AAL55435",
version 1,
source {
{
src {
db "Protein",
tag id 18071672
},
anchor "AAL55435"
}
},
seqs {
whole gi 18071672
}
}
}
},
{
type genomic,
heading "Genomic",
accession "CH471247",
version 1,
source {
{
src {
db "Nucleotide",
tag id 71514074
},
anchor "CH471247"
}
},
seqs {
whole gi 71514074
},
products {
{
type peptide,
accession "EAW55884",
version 1,
source {
{
src {
db "Protein",
tag id 119576288
},
anchor "EAW55884"
}
},
seqs {
whole gi 119576288
}
},
{
type peptide,
accession "EAW55885",
version 1,
source {
{
src {
db "Protein",
tag id 119576289
},
anchor "EAW55885"
}
},
seqs {
whole gi 119576289
}
},
{
type peptide,
accession "EAW55886",
version 1,
source {
{
src {
db "Protein",
tag id 119576290
},
anchor "EAW55886"
}
},
seqs {
whole gi 119576290
}
}
}
},
{
type genomic,
heading "Genomic",
accession "L39064",
version 1,
source {
{
src {
db "Nucleotide",
tag id 632992
},
anchor "L39064"
}
},
seqs {
whole gi 632992
},
products {
{
type peptide,
accession "AAC29513",
version 1,
source {
{
src {
db "Protein",
tag id 632993
},
anchor "AAC29513"
}
},
seqs {
whole gi 632993
}
}
}
},
{
type genomic,
heading "Genomic",
accession "S71420",
version 1,
source {
{
src {
db "Nucleotide",
tag id 551360
},
anchor "S71420"
}
},
seqs {
whole gi 551360
},
products {
{
type peptide,
accession "AAD14081",
version 1,
source {
{
src {
db "Protein",
tag id 4261781
},
anchor "AAD14081"
}
},
seqs {
whole gi 4261781
}
}
}
},
{
type mRNA,
heading "mRNA",
accession "AK303178",
version 1,
source {
{
src {
db "Nucleotide",
tag id 194381807
},
anchor "AK303178"
}
},
seqs {
whole gi 194381807
},
products {
{
type peptide,
accession "BAG64273",
version 1,
source {
{
src {
db "Protein",
tag id 194381808
},
anchor "BAG64273"
}
},
seqs {
whole gi 194381808
}
}
}
},
{
type mRNA,
heading "mRNA",
accession "BC025298",
version 1,
source {
{
src {
db "Nucleotide",
tag id 22137637
},
anchor "BC025298"
}
},
seqs {
whole gi 22137637
},
products {
{
type peptide,
text "None"
}
}
},
{
type mRNA,
heading "mRNA",
accession "BC051337",
version 1,
source {
{
src {
db "Nucleotide",
tag id 30410903
},
anchor "BC051337"
}
},
seqs {
whole gi 30410903
},
products {
{
type peptide,
accession "AAH51337",
version 1,
source {
{
src {
db "Protein",
tag id 30410904
},
anchor "AAH51337"
}
},
seqs {
whole gi 30410904
}
}
}
},
{
type mRNA,
heading "mRNA",
accession "M84747",
version 1,
source {
{
src {
db "Nucleotide",
tag id 184508
},
anchor "M84747"
}
},
seqs {
whole gi 184508
},
products {
{
type peptide,
accession "AAA58679",
version 1,
source {
{
src {
db "Protein",
tag id 184509
},
anchor "AAA58679"
}
},
seqs {
whole gi 184509
}
}
}
},
{
type mRNA,
heading "mRNA",
accession "S71404",
version 1,
source {
{
src {
db "Nucleotide",
tag id 551356
},
anchor "S71404"
}
},
seqs {
whole gi 551356
},
products {
{
type peptide,
accession "AAB30844",
version 2,
source {
{
src {
db "Protein",
tag id 13236921
},
anchor "AAB30844"
}
},
seqs {
whole gi 13236921
}
}
}
},
{
type other,
text "None",
products {
{
type peptide,
accession "Q01113",
version 3,
source {
{
src {
db "Protein",
tag id 116242526
}
},
{
src {
db "UniProtKB/Swiss-Prot",
tag str "Q01113"
}
}
},
seqs {
whole gi 116242526
}
}
}
},
{
type other-genetic,
heading "Synthetic",
accession "HQ447710",
version 1,
source {
{
src {
db "Nucleotide",
tag id 312151365
},
anchor "HQ447710"
}
},
seqs {
whole gi 312151365
},
products {
{
type peptide,
accession "ADQ32195",
version 1,
source {
{
src {
db "Protein",
tag id 312151366
},
anchor "ADQ32195"
}
},
seqs {
whole gi 312151366
}
}
}
}
}
},
{
type comment,
heading "Additional Links",
comment {
{
type comment,
source {
{
src {
db "Evidence Viewer",
tag str "3581"
},
anchor "Evidence Viewer",
url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_167198.1&gene=IL9R&lid=3581&from=6145183&to=6158419"
}
}
},
{
type comment,
source {
{
src {
db "Evidence Viewer",
tag str "3581"
},
anchor "Evidence Viewer",
url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_167206.1&gene=IL9R&lid=3581&from=296202&to=309438"
}
}
},
{
type comment,
text "MIM",
source {
{
src {
db "MIM",
tag id 300007
},
anchor "300007"
}
}
},
{
type comment,
source {
{
src {
db "AceView",
tag id 3581
},
anchor "AceView",
url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=g
eneid&org=9606&l=3581"
}
}
},
{
type comment,
text "IL9R @ LOVD",
source {
{
src {
db "IL9R",
tag str "IL9R"
},
anchor "IL9R",
url "http://www.LOVD.nl/IL9R"
}
}
},
{
type comment,
text "UCSC",
source {
{
src {
db "UCSC",
tag str "UCSC"
},
anchor "UCSC",
url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=
NM_176786"
}
}
},
{
type comment,
source {
{
src {
db "MGC",
tag str "BC051337"
},
anchor "MGC",
url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC051337"
}
}
},
{
type comment,
source {
{
src {
db "HuGE Navigator",
tag str "3581"
},
anchor "HuGE Navigator",
url "http://hugenavigator.net/HuGENavigator/huGEPedia.do?firstQu
ery=IL9R&geneID=3581&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&c
heck=y"
}
}
},
{
type comment,
source {
{
src {
db "KEGG",
tag str "hsa:3581"
},
url "http://www.genome.jp/dbget-bin/www_bget?hsa:3581"
}
}
},
{
type comment,
text "UniGene",
xtra-properties {
{
tag "UNIGENE",
value "Hs.406228"
}
},
source {
{
src {
db "UniGene",
tag str "Hs.406228"
},
anchor "Hs.406228",
url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=40
6228"
}
}
}
}
},
{
type generif,
text "Our findings suggest that overexpression of IL-9R may contribute
to the pathogenesis of diffuse large B-cell lymphoma",
refs {
pmid 23638223
},
create-date std {
year 2013,
month 11,
day 30,
hour 10,
minute 1,
second 0
},
update-date std {
year 2013,
month 11,
day 30,
hour 12,
minute 36,
second 0
}
},
{
type generif,
text "One of the identified peptide sequences corresponded to a fragment
of the human interleukin-9 receptor alpha (IL-9Ralpha).",
refs {
pmid 22638550
},
create-date std {
year 2013,
month 5,
day 11,
hour 10,
minute 1,
second 0
},
update-date std {
year 2013,
month 5,
day 11,
hour 10,
minute 42,
second 0
}
},
{
type generif,
text "analysis of IL-9 and IL-9 receptor gene polymorphisms and atopic
dermatitis in a Korean population",
refs {
pmid 21371865
},
create-date std {
year 2011,
month 7,
day 23,
hour 10,
minute 1,
second 0
},
update-date std {
year 2011,
month 7,
day 23,
hour 10,
minute 31,
second 0
}
},
{
type generif,
text "There is an association of at least 2 X-chromosomal genes with
rheumatoid arthritis: TIMP1 and IL9R.",
refs {
pmid 19723899
},
create-date std {
year 2010,
month 2,
day 15,
hour 11,
minute 2,
second 0
},
update-date std {
year 2010,
month 2,
day 15,
hour 11,
minute 13,
second 0
}
},
{
type generif,
text "These results reveal a regulatory function for IFN-gamma and IL-10
on modulating the inducible IL-9Ralpha expression levels on peripheral blood
neutrophils by T(H)2 cytokines.",
refs {
pmid 19401191
},
create-date std {
year 2009,
month 6,
day 15,
hour 11,
minute 2,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
text "IL-9Ralpha and IL-2Rbeta homodimers efficiently mediate
constitutive activation of ALL-associated JAK1 mutants.",
refs {
pmid 19139102
},
create-date std {
year 2009,
month 5,
day 9,
hour 10,
minute 1,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
text "Observational study of gene-disease association and
gene-environment interaction. (HuGE Navigator)",
refs {
pmid 20595916,
pmid 19258923
},
source {
{
src {
db "HuGENet",
tag str "3581.19258923"
},
anchor "HuGENet"
}
},
create-date std {
year 2009,
month 3,
day 25,
hour 21,
minute 36,
second 0
},
update-date std {
year 2009,
month 3,
day 25,
hour 21,
minute 36,
second 0
}
},
{
type generif,
text "Observational study of gene-disease association. (HuGE Navigator)",
refs {
pmid 20673868,
pmid 20503287,
pmid 20452482,
pmid 20424473,
pmid 19723899,
pmid 19692168,
pmid 17703412
},
source {
{
src {
db "HuGENet",
tag str "3581.17703412"
},
anchor "HuGENet"
}
},
create-date std {
year 2009,
month 3,
day 25,
hour 21,
minute 36,
second 0
},
update-date std {
year 2009,
month 3,
day 25,
hour 21,
minute 36,
second 0
}
},
{
type generif,
text "the preformed complexes between gamma c and IL-2Rbeta or
IL-9Ralpha promote signaling by the JAK3 A572V mutant without ligand,
identified in several human cancers.",
refs {
pmid 18829468
},
create-date std {
year 2009,
month 1,
day 31,
hour 10,
minute 1,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
text "Observational study of gene-disease association and gene-gene
interaction. (HuGE Navigator)",
refs {
pmid 18633131
},
source {
{
src {
db "HuGENet",
tag str "3581.18633131"
},
anchor "HuGENet"
}
},
create-date std {
year 2008,
month 9,
day 24,
hour 21,
minute 30,
second 0
},
update-date std {
year 2008,
month 9,
day 24,
hour 21,
minute 30,
second 0
}
},
{
type generif,
text "primary ATL cells, via IL-9, support the action of
IL-9Ralpha/CD14-expressing monocytes, which subsequently support the ex vivo
spontaneous proliferation of malignant T cells",
refs {
pmid 18339896
},
create-date std {
year 2008,
month 7,
day 12,
hour 10,
minute 1,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
text "IL-9R alpha was expressed on human tonsillar B cells, with an
ability to transduce signals through activation of signal transducer and
activator of transcription 3 and 5.",
refs {
pmid 17919707
},
create-date std {
year 2008,
month 2,
day 9,
hour 10,
minute 1,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
text "Human bronchial epithelium expresses interleukin-9 receptors.",
refs {
pmid 11868823
},
create-date std {
year 2007,
month 8,
day 25,
hour 10,
minute 2,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
text "Variants in the IL4RA gene alone may not exert any major influence
on susceptibility to asthma-related diseases in childhood, but in combination
with other genes, such as IL9R, IL4RA may be an important gene for disease
susceptibility",
refs {
pmid 17083349
},
create-date std {
year 2007,
month 8,
day 25,
hour 10,
minute 2,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
text "IL-9 and its receptor have roles in cell growth and malignant
transformation of lymphoid cells associated with constitutive activation of
the Jak/STAT pathway [review]",
refs {
pmid 15621723
},
create-date std {
year 2007,
month 8,
day 25,
hour 10,
minute 2,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
text "variations in the IL9R gene may influence susceptibility to
childhood wheezing and atopy, and data support the notion that different
haplotypes may have sex specific influences",
refs {
pmid 15591265
},
create-date std {
year 2007,
month 8,
day 25,
hour 10,
minute 2,
second 0
},
update-date std {
year 2010,
month 1,
day 21,
hour 0,
minute 0,
second 0
}
},
{
type generif,
heading "Interactions",
comment {
{
type generif,
text "Two-hybrid",
refs {
pmid 21988832
},
source {
{
src {
db "BioGRID",
tag id 109795
},
anchor "BioGRID"
}
},
comment {
{
type other,
source {
{
src {
db "BioGRID",
tag id 109795
}
}
}
},
{
type other,
source {
{
src {
db "GeneID",
tag id 8738
},
anchor "CRADD"
},
{
src {
db "BioGRID",
tag id 114275
}
}
}
}
},
create-date std {
year 2013,
month 4,
day 7,
hour 10,
minute 36,
second 0
},
update-date std {
year 2013,
month 12,
day 8,
hour 11,
minute 11,
second 0
}
},
{
type generif,
text "Affinity Capture-Western; Two-hybrid",
refs {
pmid 10486269
},
source {
{
src {
db "BioGRID",
tag id 109795
},
anchor "BioGRID"
}
},
comment {
{
type other,
source {
{
src {
db "BioGRID",
tag id 109795
}
}
}
},
{
type other,
source {
{
src {
db "GeneID",
tag id 10524
},
anchor "KAT5"
},
{
src {
db "BioGRID",
tag id 115779
}
}
}
}
},
create-date std {
year 2012,
month 7,
day 8,
hour 10,
minute 24,
second 0
},
update-date std {
year 2013,
month 12,
day 8,
hour 11,
minute 11,
second 0
}
},
{
type generif,
refs {
pmid 10486269
},
source {
{
src {
db "HPRD",
tag str "02052"
},
anchor "HPRD"
}
},
comment {
{
type peptide,
source {
{
src {
db "Protein",
tag id 116242526
},
anchor "Q01113"
}
}
},
{
type peptide,
source {
{
src {
db "GeneID",
tag id 10524
},
anchor "KAT5"
},
{
src {
db "Protein",
tag id 30923328
},
anchor "Q92993"
}
}
}
},
create-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 28,
second 0
},
update-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 31,
second 0
}
},
{
type generif,
refs {
pmid 10642536
},
source {
{
src {
db "HPRD",
tag str "02052"
},
anchor "HPRD"
}
},
comment {
{
type peptide,
source {
{
src {
db "Protein",
tag id 116242526
},
anchor "Q01113"
}
}
},
{
type peptide,
source {
{
src {
db "GeneID",
tag id 7534
},
anchor "YWHAZ"
},
{
src {
db "Protein",
tag id 52000887
},
anchor "P63104"
}
}
}
},
create-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 28,
second 0
},
update-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 31,
second 0
}
},
{
type generif,
refs {
pmid 11418623
},
source {
{
src {
db "HPRD",
tag str "02052"
},
anchor "HPRD"
}
},
comment {
{
type peptide,
source {
{
src {
db "Protein",
tag id 116242526
},
anchor "Q01113"
}
}
},
{
type peptide,
source {
{
src {
db "GeneID",
tag id 3561
},
anchor "IL2RG"
},
{
src {
db "Protein",
tag id 400048
},
anchor "P31785"
}
}
}
},
create-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 28,
second 0
},
update-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 31,
second 0
}
},
{
type generif,
refs {
pmid 8756628
},
source {
{
src {
db "HPRD",
tag str "02052"
},
anchor "HPRD"
}
},
comment {
{
type peptide,
source {
{
src {
db "Protein",
tag id 116242526
},
anchor "Q01113"
}
}
},
{
type peptide,
source {
{
src {
db "GeneID",
tag id 3716
},
anchor "JAK1"
},
{
src {
db "Protein",
tag id 215274013
},
anchor "P23458"
}
}
}
},
create-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 28,
second 0
},
update-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 31,
second 0
}
},
{
type generif,
refs {
pmid 11588013
},
source {
{
src {
db "HPRD",
tag str "02052"
},
anchor "HPRD"
}
},
comment {
{
type peptide,
source {
{
src {
db "Protein",
tag id 116242526
},
anchor "Q01113"
}
}
},
{
type peptide,
source {
{
src {
db "GeneID",
tag id 3578
},
anchor "IL9"
},
{
src {
db "Protein",
tag id 124362
},
anchor "P15248"
}
}
}
},
create-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 28,
second 0
},
update-date std {
year 2009,
month 12,
day 17,
hour 15,
minute 31,
second 0
}
},
{
type generif,
text "Affinity Capture-Western; Two-hybrid",
refs {
pmid 10642536
},
source {
{
src {
db "BioGRID",
tag id 109795
},
anchor "BioGRID"
}
},
comment {
{
type other,
source {
{
src {
db "BioGRID",
tag id 109795
}
}
}
},
{
type other,
source {
{
src {
db "GeneID",
tag id 7534
},
anchor "YWHAZ"
},
{
src {
db "BioGRID",
tag id 113366
}
}
}
}
},
create-date std {
year 2008,
month 12,
day 23,
hour 9,
minute 6,
second 0
},
update-date std {
year 2013,
month 12,
day 8,
hour 11,
minute 11,
second 0
}
},
{
type generif,
text "Affinity Capture-Western",
refs {
pmid 8756628
},
source {
{
src {
db "BioGRID",
tag id 109795
},
anchor "BioGRID"
}
},
comment {
{
type other,
source {
{
src {
db "BioGRID",
tag id 109795
}
}
}
},
{
type other,
source {
{
src {
db "GeneID",
tag id 3716
},
anchor "JAK1"
},
{
src {
db "BioGRID",
tag id 109919
}
}
}
}
},
create-date std {
year 2008,
month 12,
day 23,
hour 9,
minute 6,
second 0
},
update-date std {
year 2013,
month 12,
day 8,
hour 11,
minute 11,
second 0
}
}
}
},
{
type comment,
heading "Pathways",
comment {
{
type comment,
text "KEGG pathway: Cytokine-cytokine receptor interaction",
source {
{
src {
db "KEGG pathway",
tag str "04060"
},
anchor "04060",
url "http://www.genome.jp/dbget-bin/show_pathway?hsa04060+3581"
}
}
},
{
type comment,
text "KEGG pathway: Hematopoietic cell lineage",
source {
{
src {
db "KEGG pathway",
tag str "04640"
},
anchor "04640",
url "http://www.genome.jp/dbget-bin/show_pathway?hsa04640+3581"
}
}
},
{
type comment,
text "KEGG pathway: Jak-STAT signaling pathway",
source {
{
src {
db "KEGG pathway",
tag str "04630"
},
anchor "04630",
url "http://www.genome.jp/dbget-bin/show_pathway?hsa04630+3581"
}
}
}
}
},
{
type comment,
heading "Markers (Sequence Tagged Sites/STS)",
comment {
{
type comment,
source {
{
src {
db "UniSTS",
tag id 85806
},
anchor "RH69191",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 296037
},
anchor "ECD15020",
post-text "(e-PCR)"
}
}
}
}
},
{
type comment,
heading "Gene Location History",
comment {
{
type comment,
heading "Homo sapiens Annotation Release 105",
comment {
{
type assembly,
heading "GRCh37.p13",
label "Reference",
accession "GCF_000001405",
version 25,
comment {
{
type assembly-unit,
heading "Primary Assembly",
accession "GCF_000001305",
version 13,
comment {
{
type genomic,
label "chromosome Chromosome X",
accession "NC_000023",
version 10,
seqs {
int {
from 155227245,
to 155240481,
strand plus,
id gi 224589822
}
}
},
{
type genomic,
label "chromosome Chromosome Y",
accession "NC_000024",
version 9,
seqs {
int {
from 59330251,
to 59343487,
strand plus,
id gi 224589823
}
}
}
}
}
}
},
{
type assembly,
heading "HuRef",
label "Alternate",
accession "GCF_000002125",
version 1,
comment {
{
type genomic,
label "chromosome Chromosome X",
accession "AC_000155",
version 1,
seqs {
int {
from 143710175,
to 143723406,
strand plus,
id gi 157734237
}
}
}
}
},
{
type assembly,
heading "CHM1_1.1",
label "Alternate",
accession "GCF_000306695",
version 2,
comment {
{
type genomic,
label "chromosome Chromosome X",
accession "NC_018934",
version 2,
seqs {
int {
from 155138862,
to 155152088,
strand plus,
id gi 528476524
}
}
}
}
}
}
},
{
type comment,
heading "Homo sapiens Annotation Release 104",
comment {
{
type assembly,
heading "GRCh37.p10",
label "Reference",
accession "GCF_000001405",
version 22,
comment {
{
type assembly-unit,
heading "Primary Assembly",
accession "GCF_000001305",
version 13,
comment {
{
type genomic,
label "chromosome Chromosome X",
accession "NC_000023",
version 10,
seqs {
int {
from 155227245,
to 155240481,
strand plus,
id gi 224589822
}
}
},
{
type genomic,
label "chromosome Chromosome Y",
accession "NC_000024",
version 9,
seqs {
int {
from 59330251,
to 59343487,
strand plus,
id gi 224589823
}
}
}
}
}
}
},
{
type assembly,
heading "HuRef",
label "Alternate",
accession "GCF_000002125",
version 1,
comment {
{
type genomic,
label "chromosome Chromosome X",
accession "AC_000155",
version 1,
seqs {
int {
from 143710175,
to 143723406,
strand plus,
id gi 157734237
}
}
}
}
},
{
type assembly,
heading "CHM1_1.0",
label "Alternate",
accession "GCF_000306695",
version 1,
comment {
{
type genomic,
label "chromosome Chromosome X",
accession "NC_018934",
version 1,
seqs {
int {
from 155094217,
to 155107460,
strand plus,
id gi 409253441
}
}
}
}
}
}
},
{
type comment,
heading "Build 37.3",
comment {
{
type assembly,
heading "GRCh37.p5",
label "Reference",
accession "GCF_000001405",
version 17,
comment {
{
type assembly-unit,
heading "Primary Assembly",
accession "GCF_000001305",
version 13,
comment {
{
type genomic,
label "chromosome Chromosome X",
accession "NC_000023",
version 10,
seqs {
int {
from 155227245,
to 155240481,
strand plus,
id gi 224589822
}
}
},
{
type genomic,
label "chromosome Chromosome Y",
accession "NC_000024",
version 9,
seqs {
int {
from 59330251,
to 59343487,
strand plus,
id gi 224589823
}
}
}
}
}
}
},
{
type assembly,
heading "HuRef",
label "Alternate",
accession "GCF_000002125",
version 1,
comment {
{
type assembly-unit,
heading "Primary Assembly",
accession "GCF_000000025",
version 1,
comment {
{
type genomic,
label "chromosome Chromosome X",
accession "AC_000155",
version 1,
seqs {
int {
from 143710175,
to 143723406,
strand plus,
id gi 157734237
}
}
}
}
}
}
}
}
}
}
}
},
unique-keys {
{
db "HGNC",
tag id 6030
},
{
db "LocusID",
tag id 3581
},
{
db "MIM",
tag id 300007
}
},
xtra-index-terms {
"LOC3581"
}
}
Entrezgene ::= {
track-info {
geneid 56111,
status live,
create-date std {
year 2000,
month 7,
day 13
},
update-date std {
year 2013,
month 12,
day 3,
hour 17,
minute 40,
second 0
}
},
type protein-coding,
source {
genome genomic,
origin natural,
org {
taxname "Homo sapiens",
common "human",
db {
{
db "taxon",
tag id 9606
}
},
syn {
"man"
},
orgname {
name binomial {
genus "Homo",
species "sapiens"
},
lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo",
gcode 1,
mgcode 2,
div "PRI",
pgcode 0
}
},
subtype {
{
subtype chromosome,
name "5"
}
}
},
gene {
locus "PCDHGA4",
desc "protocadherin gamma subfamily A, 4",
maploc "5q31",
db {
{
db "HGNC",
tag id 8702
},
{
db "Ensembl",
tag str "ENSG00000262576"
},
{
db "HPRD",
tag str "09381"
},
{
db "MIM",
tag id 606291
},
{
db "Vega",
tag str "OTTHUMG00000177593"
}
},
syn {
"PCDH-GAMMA-A4"
}
},
prot {
name {
"protocadherin gamma-A4"
},
desc "protocadherin gamma-A4"
},
summary "This gene is a member of the protocadherin gamma gene cluster, one
of three related clusters tandemly linked on chromosome five. These gene
clusters have an immunoglobulin-like organization, suggesting that a novel
mechanism may be involved in their regulation and expression. The gamma gene
cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12
genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly
related subfamily C contains 3 genes. The tandem array of 22 large, variable
region exons are followed by a constant region, containing 3 exons shared by
all genes in the cluster. Each variable region exon encodes the extracellular
region, which includes 6 cadherin ectodomains and a transmembrane region. The
constant region exons encode the common cytoplasmic region. These neural
cadherin-like cell adhesion proteins most likely play a critical role in the
establishment and function of specific cell-cell connections in the brain.
Alternative splicing has been described for the gamma cluster genes.
[provided by RefSeq, Jul 2008]",
location {
{
display-str "5q31",
method map-type cyto
}
},
gene-source {
src "LocusLink",
src-int 56111,
src-str2 "56111"
},
locus {
{
type genomic,
heading "Reference GRCh37.p13 Primary Assembly",
label "chromosome 5 reference GRCh37.p13 Primary Assembly",
accession "NC_000005",
version 9,
seqs {
int {
from 140734767,
to 140892545,
strand plus,
id gi 224589817
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_018917",
version 2,
genomic-coords {
mix {
int {
from 140734767,
to 140737187,
strand plus,
id gi 224589817
},
int {
from 140874373,
to 140874431,
strand plus,
id gi 224589817
},
int {
from 140884959,
to 140885047,
strand plus,
id gi 224589817
},
int {
from 140890513,
to 140892545,
strand plus,
id gi 224589817
}
}
},
seqs {
whole gi 14196466
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_061740",
version 1,
source {
{
src {
db "CCDS",
tag str "CCDS58979.1"
},
anchor "CCDS58979.1"
}
},
genomic-coords {
mix {
int {
from 140734767,
to 140737187,
strand plus,
id gi 224589817
},
int {
from 140874373,
to 140874431,
strand plus,
id gi 224589817
},
int {
from 140884959,
to 140885047,
strand plus,
id gi 224589817
},
int {
from 140890513,
to 140890739,
strand plus,
id gi 224589817
}
}
},
seqs {
whole gi 11056026
}
}
}
},
{
type mRNA,
heading "Reference",
label "transcript variant 2",
accession "NM_032053",
version 1,
genomic-coords {
int {
from 140734767,
to 140737295,
strand plus,
id gi 224589817
}
},
seqs {
whole gi 14196467
},
products {
{
type peptide,
heading "Reference",
label "isoform 2",
accession "NP_114442",
version 1,
genomic-coords {
int {
from 140734767,
to 140737229,
strand plus,
id gi 224589817
}
},
seqs {
whole gi 14196468
}
}
}
}
}
},
{
type genomic,
heading "Reference assembly",
label "genomic region",
accession "NG_000012",
version 2,
seqs {
int {
from 65221,
to 223175,
strand plus,
id gi 50284693
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_018917",
version 3,
genomic-coords {
mix {
int {
from 65221,
to 67817,
strand plus,
id gi 50284693
},
int {
from 205003,
to 205061,
strand plus,
id gi 50284693
},
int {
from 215589,
to 215677,
strand plus,
id gi 50284693
},
int {
from 221143,
to 223175,
strand plus,
id gi 50284693
}
}
},
seqs {
whole gi 523567547
}
},
{
type mRNA,
heading "Reference",
label "transcript variant 2",
accession "NM_032053",
version 2,
genomic-coords {
int {
from 65221,
to 67926,
strand plus,
id gi 50284693
}
},
seqs {
whole gi 523567549
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_061740",
version 2,
source {
{
src {
db "CCDS",
tag str "CCDS58979.1"
},
anchor "CCDS58979.1"
}
},
genomic-coords {
mix {
int {
from 65304,
to 67817,
strand plus,
id gi 50284693
},
int {
from 205003,
to 205061,
strand plus,
id gi 50284693
},
int {
from 215589,
to 215677,
strand plus,
id gi 50284693
},
int {
from 221143,
to 221369,
strand plus,
id gi 50284693
}
}
},
seqs {
whole gi 523567548
}
},
{
type peptide,
heading "Reference",
label "isoform 2 precursor",
accession "NP_114442",
version 2,
genomic-coords {
int {
from 65304,
to 67859,
strand plus,
id gi 50284693
}
},
seqs {
whole gi 523567550
}
}
}
}
}
},
{
type genomic,
heading "Alternate CHM1_1.1",
label "chromosome 5 alternate CHM1_1.1",
accession "NC_018916",
version 2,
seqs {
int {
from 140167974,
to 140325822,
strand plus,
id gi 528476642
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_018917",
version 2,
genomic-coords {
mix {
int {
from 140167974,
to 140170394,
strand plus,
id gi 528476642
},
int {
from 140307638,
to 140307696,
strand plus,
id gi 528476642
},
int {
from 140318237,
to 140318325,
strand plus,
id gi 528476642
},
int {
from 140323790,
to 140325822,
strand plus,
id gi 528476642
}
}
},
seqs {
whole gi 14196466
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_061740",
version 1,
genomic-coords {
mix {
int {
from 140167974,
to 140170394,
strand plus,
id gi 528476642
},
int {
from 140307638,
to 140307696,
strand plus,
id gi 528476642
},
int {
from 140318237,
to 140318325,
strand plus,
id gi 528476642
},
int {
from 140323790,
to 140324016,
strand plus,
id gi 528476642
}
}
},
seqs {
whole gi 11056026
}
}
}
},
{
type mRNA,
heading "Reference",
label "transcript variant 2",
accession "NM_032053",
version 1,
genomic-coords {
int {
from 140167974,
to 140170502,
strand plus,
id gi 528476642
}
},
seqs {
whole gi 14196467
},
products {
{
type peptide,
heading "Reference",
label "isoform 2",
accession "NP_114442",
version 1,
genomic-coords {
int {
from 140167974,
to 140170436,
strand plus,
id gi 528476642
}
},
seqs {
whole gi 14196468
}
}
}
}
}
},
{
type genomic,
heading "Alternate HuRef",
label "chromosome 5 alternate HuRef",
accession "AC_000137",
version 1,
seqs {
int {
from 135879842,
to 136037385,
strand plus,
id gi 157734151
}
},
products {
{
type mRNA,
heading "Reference",
label "transcript variant 1",
accession "NM_018917",
version 2,
genomic-coords {
mix {
int {
from 135879842,
to 135882262,
strand plus,
id gi 157734151
},
int {
from 136019211,
to 136019269,
strand plus,
id gi 157734151
},
int {
from 136029799,
to 136029887,
strand plus,
id gi 157734151
},
int {
from 136035353,
to 136037385,
strand plus,
id gi 157734151
}
}
},
seqs {
whole gi 14196466
},
products {
{
type peptide,
heading "Reference",
label "isoform 1 precursor",
accession "NP_061740",
version 1,
genomic-coords {
mix {
int {
from 135879842,
to 135882262,
strand plus,
id gi 157734151
},
int {
from 136019211,
to 136019269,
strand plus,
id gi 157734151
},
int {
from 136029799,
to 136029887,
strand plus,
id gi 157734151
},
int {
from 136035353,
to 136035579,
strand plus,
id gi 157734151
}
}
},
seqs {
whole gi 11056026
}
}
}
},
{
type mRNA,
heading "Reference",
label "transcript variant 2",
accession "NM_032053",
version 1,
genomic-coords {
int {
from 135879842,
to 135882370,
strand plus,
id gi 157734151
}
},
seqs {
whole gi 14196467
},
products {
{
type peptide,
heading "Reference",
label "isoform 2",
accession "NP_114442",
version 1,
genomic-coords {
int {
from 135879842,
to 135882304,
strand plus,
id gi 157734151
}
},
seqs {
whole gi 14196468
}
}
}
}
}
}
},
properties {
{
type comment,
label "Nomenclature",
source {
{
anchor "HUGO Gene Nomenclature Committee"
}
},
properties {
{
type property,
label "Official Symbol",
text "PCDHGA4"
},
{
type property,
label "Official Full Name",
text "protocadherin gamma subfamily A, 4"
}
}
},
{
type comment,
heading "GeneOntology",
source {
{
pre-text "Provided by",
anchor "GOA",
url "http://www.ebi.ac.uk/GOA/"
}
},
comment {
{
type comment,
label "Function",
comment {
{
type comment,
source {
{
src {
db "GO",
tag id 5509
},
anchor "calcium ion binding",
post-text "evidence: IEA"
}
}
}
}
},
{
type comment,
label "Process",
comment {
{
type comment,
source {
{
src {
db "GO",
tag id 7156
},
anchor "homophilic cell adhesion",
post-text "evidence: IEA"
}
}
}
}
},
{
type comment,
label "Component",
comment {
{
type comment,
source {
{
src {
db "GO",
tag id 16021
},
anchor "integral to membrane",
post-text "evidence: IEA"
}
}
},
{
type comment,
source {
{
src {
db "GO",
tag id 5886
},
anchor "plasma membrane",
post-text "evidence: IEA"
}
}
}
}
}
}
}
},
homology {
{
type comment,
heading "Mouse, Rat",
source {
{
src {
db "HomoloGene",
tag id 81866
},
anchor "Map Viewer",
url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=5&M
APS=genes-r-org/rat-chr/human%3A5,genes-r-org/mouse-chr/human%3A5,genes-r-org/
human-chr5&query=e%3A56111[egene_id]+AND+gene[obj_type]&QSTR=pcdhga4&cmd=focus
&fill=10"
}
}
}
},
comments {
{
type comment,
heading "RefSeq Status",
label "REVIEWED"
},
{
type comment,
refs {
pmid 16344560,
pmid 11230163,
pmid 10835267,
pmid 10817752,
pmid 10716726,
pmid 10380929
}
},
{
type comment,
heading "NCBI Reference Sequences (RefSeq)",
comment {
{
type comment,
heading "RefSeqs maintained independently of Annotated Genomes",
products {
{
type mRNA,
heading "mRNA Sequence",
accession "NM_018917",
version 3,
source {
{
src {
db "Nucleotide",
tag id 523567547
},
anchor "NM_018917"
}
},
seqs {
whole gi 523567547
},
products {
{
type peptide,
heading "Product",
accession "NP_061740",
version 2,
source {
{
src {
db "Protein",
tag id 523567548
},
anchor "NP_061740",
post-text "protocadherin gamma-A4 isoform 1 precursor"
}
},
seqs {
whole gi 523567548
},
comment {
{
type other,
heading "Conserved Domains",
source {
{
pre-text "(6)",
anchor "summary"
}
},
comment {
{
type other,
source {
{
src {
db "CDD",
tag id 206637
},
anchor "cd11304: Cadherin_repeat; Cadherin
tandem repeat domain"
}
},
comment {
{
type other,
text "Location: 277 - 374 Blast Score: 278"
},
{
type other,
text "Location: 393 - 479 Blast Score: 236"
},
{
type other,
text "Location: 170 - 269 Blast Score: 227"
},
{
type other,
text "Location: 610 - 697 Blast Score: 223"
},
{
type other,
text "Location: 487 - 589 Blast Score: 221"
},
{
type other,
text "Location: 64 - 160 Blast Score: 123"
}
}
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Ensembl",
tag str "ENSP00000458570"
}
}
}
},
{
type other,
heading "UniProtKB",
source {
},
comment {
{
type other,
source {
{
src {
db "UniProtKB/Swiss-Prot",
tag str "Q9Y5G9"
},
anchor "Q9Y5G9"
}
}
}
}
},
{
type other,
heading "Consensus CDS (CCDS)",
source {
{
src {
db "CCDS",
tag str "CCDS58979.1"
},
anchor "CCDS58979.1"
}
},
comment {
{
type other,
heading "CCDS Note",
text "The coding region has been updated to extend
the N-terminus to one that is more supported by the available transcript and
primate conservation data. "
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Vega",
tag str "OTTHUMP00000257173"
}
}
}
}
}
}
},
comment {
{
type comment,
label "RefSeq Status",
text "REVIEWED"
},
{
type comment,
heading "Transcriptional Variant",
comment {
{
type comment,
text "Transcript Variant: This variant (1) includes the
constant region exons and encodes the longest isoform (1)."
}
}
},
{
type other,
heading "Source Sequence",
source {
{
src {
db "Nucleotide",
tag str "AF152324,DA392480"
},
anchor "AF152324,DA392480"
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Ensembl",
tag str "ENST00000571252"
}
}
}
},
{
type other,
heading "Related",
source {
{
src {
db "Vega",
tag str "OTTHUMT00000437959"
}
}
}
}
}
},
{
type mRNA,
heading "mRNA Sequence",
accession "NM_032053",
version 2,
source {
{
src {
db "Nucleotide",
tag id 523567549
},
anchor "NM_032053"
}
},
seqs {
whole gi 523567549
},
products {
{
type peptide,
heading "Product",
accession "NP_114442",
version 2,
source {
{
src {
db "Protein",
tag id 523567550
},
anchor "NP_114442",
post-text "protocadherin gamma-A4 isoform 2 precursor"
}
},
seqs {
whole gi 523567550
},
comment {
{
type other,
heading "Conserved Domains",
source {
{
pre-text "(6)",
anchor "summary"
}
},
comment {
{
type other,
source {
{
src {
db "CDD",
tag id 206637
},
anchor "cd11304: Cadherin_repeat; Cadherin
tandem repeat domain"
}
},
comment {
{
type other,
text "Location: 277 - 374 Blast Score: 275"
},
{
type other,
text "Location: 393 - 479 Blast Score: 233"
},
{
type other,
text "Location: 170 - 269 Blast Score: 224"
},
{
type other,
text "Location: 610 - 697 Blast Score: 220"
},
{
type other,
text "Location: 487 - 589 Blast Score: 218"
},
{
type other,
text "Location: 64 - 160 Blast Score: 121"
}
}
}
}
},
{
type other,
heading "UniProtKB",
source {
},
comment {
{
type other,
source {
{
src {
db "UniProtKB/Swiss-Prot",
tag str "Q9Y5G9"
},
anchor "Q9Y5G9"
}
}
}
}
}
}
}
},
comment {
{
type comment,
label "RefSeq Status",
text "REVIEWED"
},
{
type comment,
heading "Transcriptional Variant",
comment {
{
type comment,
text "Transcript Variant: This variant (2) utilizes the
large, first exon then continues into the downstream intron 1 sequence before
terminating. This one-exon transcript encodes the shorter isoform (2)."
}
}
},
{
type other,
heading "Source Sequence",
source {
{
src {
db "Nucleotide",
tag str "AF152511,BX100615,DA392480"
},
anchor "AF152511,BX100615,DA392480"
}
}
}
}
}
},
comment {
{
type genomic,
heading "Reference",
accession "NG_000012",
version 2,
source {
{
src {
db "Nucleotide",
tag id 50284693
},
anchor "NG_000012"
}
},
seqs {
int {
from 65221,
to 223175,
strand plus,
id gi 50284693
}
}
}
}
},
{
type comment,
heading "RefSeqs of Annotated Genomes: Homo sapiens Annotation
Release 105",
products {
{
type genomic,
heading "Reference GRCh37.p13 Primary Assembly",
accession "NC_000005",
version 9,
source {
{
src {
db "Nucleotide",
tag id 224589817
}
}
},
seqs {
int {
from 140734767,
to 140892545,
strand plus,
id gi 224589817
}
}
},
{
type genomic,
heading "Alternate HuRef",
accession "AC_000137",
version 1,
source {
{
src {
db "Nucleotide",
tag id 157734151
}
}
},
seqs {
int {
from 135879842,
to 136037385,
strand plus,
id gi 157734151
}
}
},
{
type genomic,
heading "Alternate CHM1_1.1",
accession "NC_018916",
version 2,
source {
{
src {
db "Nucleotide",
tag id 528476642
}
}
},
seqs {
int {
from 140167974,
to 140325822,
strand plus,
id gi 528476642
}
}
}
}
}
}
},
{
type comment,
heading "Related Sequences",
products {
{
type genomic,
heading "Genomic",
accession "ABBA01026410",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148165753
},
anchor "ABBA01026410"
}
},
seqs {
int {
from 18242,
to 75873,
strand minus,
id gi 148165753
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "ABBA01026411",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148165752
},
anchor "ABBA01026411"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "ABBA01026412",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148165751
},
anchor "ABBA01026412"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "ABBA01026413",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148165750
},
anchor "ABBA01026413"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "ABBA01026414",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148165749
},
anchor "ABBA01026414"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "ABBA01026415",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148165748
},
anchor "ABBA01026415"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "ABBA01026416",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148165747
},
anchor "ABBA01026416"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "ABBA01026417",
version 1,
source {
{
src {
db "Nucleotide",
tag id 148165746
},
anchor "ABBA01026417"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AC005366",
version 1,
source {
{
src {
db "Nucleotide",
tag id 3367508
},
anchor "AC005366"
}
},
seqs {
int {
from 17974,
to 36136,
strand minus,
id gi 3367508
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AC005618",
version 1,
source {
{
src {
db "Nucleotide",
tag id 3548785
},
anchor "AC005618"
}
},
seqs {
int {
from 66536,
to 176713,
strand plus,
id gi 3548785
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AC008781",
version 7,
source {
{
src {
db "Nucleotide",
tag id 16303400
},
anchor "AC008781"
}
},
seqs {
int {
from 138117,
to 185893,
strand minus,
id gi 16303400
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AL832028",
version 1,
source {
{
src {
db "Nucleotide",
tag id 21732568
},
anchor "AL832028"
}
},
seqs {
whole gi 21732568
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AMYH02012344",
version 1,
source {
{
src {
db "Nucleotide",
tag id 511816418
},
anchor "AMYH02012344"
}
},
seqs {
int {
from 151138,
to 175836,
strand plus,
id gi 511816418
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AMYH02012345",
version 1,
source {
{
src {
db "Nucleotide",
tag id 511816417
},
anchor "AMYH02012345"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "AMYH02012346",
version 1,
source {
{
src {
db "Nucleotide",
tag id 511816416
},
anchor "AMYH02012346"
}
},
products {
{
type peptide,
text "None"
}
}
},
{
type genomic,
heading "Genomic",
accession "CH471062",
version 2,
source {
{
src {
db "Nucleotide",
tag id 74230048
},
anchor "CH471062"
}
},
seqs {
whole gi 74230048
},
products {
{
type peptide,
accession "EAW61957",
version 1,
source {
{
src {
db "Protein",
tag id 119582361
},
anchor "EAW61957"
}
},
seqs {
whole gi 119582361
}
},
{
type peptide,
accession "EAW61964",
version 1,
source {
{
src {
db "Protein",
tag id 119582368
},
anchor "EAW61964"
}
},
seqs {
whole gi 119582368
}
}
}
},
{
type mRNA,
heading "mRNA",
accession "AF152324",
version 1,
source {
{
src {
db "Nucleotide",
tag id 5456939
},
anchor "AF152324"
}
},
seqs {
whole gi 5456939
},
products {
{
type peptide,
accession "AAD43718",
version 1,
source {
{
src {
db "Protein",
tag id 5456940
},
anchor "AAD43718"
}
},
seqs {
whole gi 5456940
}
}
}
},
{
type mRNA,
heading "mRNA",
accession "AF152511",
version 1,
source {
{
src {
db "Nucleotide",
tag id 5457069
},
anchor "AF152511"
}
},
seqs {
whole gi 5457069
},
products {
{
type peptide,
accession "AAD43771",
version 1,
source {
{
src {
db "Protein",
tag id 5457070
},
anchor "AAD43771"
}
},
seqs {
whole gi 5457070
}
}
}
},
{
type mRNA,
heading "mRNA",
accession "AI805761",
version 1,
source {
{
src {
db "Nucleotide",
tag id 5392327
},
anchor "AI805761"
}
},
seqs {
whole gi 5392327
},
products {
{
type peptide,
text "None"
}
}
},
{
type mRNA,
heading "mRNA",
accession "BX100615",
version 1,
source {
{
src {
db "Nucleotide",
tag id 27830686
},
anchor "BX100615"
}
},
seqs {
whole gi 27830686
},
products {
{
type peptide,
text "None"
}
}
},
{
type mRNA,
heading "mRNA",
accession "DA392480",
version 1,
source {
{
src {
db "Nucleotide",
tag id 80578107
},
anchor "DA392480"
}
},
seqs {
whole gi 80578107
},
products {
{
type peptide,
text "None"
}
}
},
{
type other,
text "None",
products {
{
type peptide,
accession "Q9Y5G9",
version 1,
source {
{
src {
db "Protein",
tag id 37999839
}
},
{
src {
db "UniProtKB/Swiss-Prot",
tag str "Q9Y5G9"
}
}
},
seqs {
whole gi 37999839
}
}
}
},
{
type other-genetic,
heading "Synthetic",
accession "BC152812",
version 1,
source {
{
src {
db "Nucleotide",
tag id 157170235
},
anchor "BC152812"
}
},
seqs {
whole gi 157170235
},
products {
{
type peptide,
accession "AAI52813",
version 1,
source {
{
src {
db "Protein",
tag id 157170236
},
anchor "AAI52813"
}
},
seqs {
whole gi 157170236
}
}
}
},
{
type other-genetic,
heading "Synthetic",
accession "BC156730",
version 1,
source {
{
src {
db "Nucleotide",
tag id 162318805
},
anchor "BC156730"
}
},
seqs {
whole gi 162318805
},
products {
{
type peptide,
accession "AAI56731",
version 1,
source {
{
src {
db "Protein",
tag id 162318806
},
anchor "AAI56731"
}
},
seqs {
whole gi 162318806
}
}
}
}
}
},
{
type comment,
heading "Additional Links",
comment {
{
type comment,
source {
{
src {
db "Evidence Viewer",
tag str "56111"
},
anchor "Evidence Viewer",
url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_029289.11&gene=PCDHGA4&lid=56111&from=1897694&to=2055472"
}
}
},
{
type comment,
text "MIM",
source {
{
src {
db "MIM",
tag id 606291
},
anchor "606291"
}
}
},
{
type comment,
source {
{
src {
db "AceView",
tag id 56111
},
anchor "AceView",
url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=g
eneid&org=9606&l=56111"
}
}
},
{
type comment,
text "UCSC",
source {
{
src {
db "UCSC",
tag str "UCSC"
},
anchor "UCSC",
url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=
NM_018917"
}
}
},
{
type comment,
source {
{
src {
db "MGC",
tag str "BC152812,BC156730"
},
anchor "MGC",
url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC152812
,BC156730"
}
}
},
{
type comment,
source {
{
src {
db "KEGG",
tag str "hsa:56111"
},
url "http://www.genome.jp/dbget-bin/www_bget?hsa:56111"
}
}
},
{
type comment,
text "UniGene",
xtra-properties {
{
tag "UNIGENE",
value "Hs.368160"
}
},
source {
{
src {
db "UniGene",
tag str "Hs.368160"
},
anchor "Hs.368160",
url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=36
8160"
}
}
}
}
},
{
type comment,
heading "Markers (Sequence Tagged Sites/STS)",
comment {
{
type comment,
source {
{
src {
db "UniSTS",
tag id 68872
},
anchor "SHGC-76190",
post-text "(e-PCR)"
}
},
comment {
{
type other,
label "Alternate name",
text "HSA.981"
},
{
type other,
label "Alternate name",
text "RH101644"
},
{
type other,
label "Alternate name",
text "RH50318"
},
{
type other,
label "Alternate name",
text "STS-L11373"
},
{
type other,
label "Alternate name",
text "WI-18887"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 58378
},
anchor "T03558",
post-text "(e-PCR)"
}
},
comment {
{
type other,
label "Alternate name",
text "IB475"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 277566
},
anchor "PCDHGA9_1502",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 277567
},
anchor "PCDHGC3__1203",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 280897
},
anchor "PCDHGA4_2560",
post-text "(e-PCR)"
}
},
comment {
{
type other,
label "Alternate name",
text "PCDHGA4_2560.2"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 280898
},
anchor "PCDHGA6_2010",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 280900
},
anchor "PCDHGB4_2544",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 280901
},
anchor "PCDHGC4_2483",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 47440
},
anchor "AF022190",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 87645
},
anchor "RH91455",
post-text "(e-PCR)"
}
},
comment {
{
type other,
label "Alternate name",
text "stSG44640"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 256698
},
anchor "5q31-33_24",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 25793
},
anchor "AF053066",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 25794
},
anchor "AF022189",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 466384
},
anchor "PCDHGA10_7046",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 73201
},
anchor "D5S2538",
post-text "(e-PCR)"
}
},
comment {
{
type other,
label "Alternate name",
text "GDB:734416"
},
{
type other,
label "Alternate name",
text "RH34348"
},
{
type other,
label "Alternate name",
text "SHGC-5561"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 256498
},
anchor "5q31-33_16",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 256499
},
anchor "5q31-33_17",
post-text "(e-PCR)"
}
}
},
{
type comment,
source {
{
src {
db "UniSTS",
tag id 50676
},
anchor "STS-R97031",
post-text "(e-PCR)"
}
},
comment {
{
type other,
label "Alternate name",
text "RH41214"
},
{
type other,
label "Alternate name",
text "sts-R97031"
}
}
}
}
},
{
type comment,
heading "Gene Location History",
comment {
{
type comment,
heading "Homo sapiens Annotation Release 105",
comment {
{
type assembly,
heading "GRCh37.p13",
label "Reference",
accession "GCF_000001405",
version 25,
comment {
{
type assembly-unit,
heading "Primary Assembly",
accession "GCF_000001305",
version 13,
comment {
{
type genomic,
label "chromosome Chromosome 5",
accession "NC_000005",
version 9,
seqs {
int {
from 140734767,
to 140892545,
strand plus,
id gi 224589817
}
}
}
}
}
}
},
{
type assembly,
heading "HuRef",
label "Alternate",
accession "GCF_000002125",
version 1,
comment {
{
type genomic,
label "chromosome Chromosome 5",
accession "AC_000137",
version 1,
seqs {
int {
from 135879842,
to 136037385,
strand plus,
id gi 157734151
}
}
}
}
},
{
type assembly,
heading "CHM1_1.1",
label "Alternate",
accession "GCF_000306695",
version 2,
comment {
{
type genomic,
label "chromosome Chromosome 5",
accession "NC_018916",
version 2,
seqs {
int {
from 140167974,
to 140325822,
strand plus,
id gi 528476642
}
}
}
}
}
}
},
{
type comment,
heading "Homo sapiens Annotation Release 104",
comment {
{
type assembly,
heading "GRCh37.p10",
label "Reference",
accession "GCF_000001405",
version 22,
comment {
{
type assembly-unit,
heading "Primary Assembly",
accession "GCF_000001305",
version 13,
comment {
{
type genomic,
label "chromosome Chromosome 5",
accession "NC_000005",
version 9,
seqs {
int {
from 140734767,
to 140892545,
strand plus,
id gi 224589817
}
}
}
}
}
}
},
{
type assembly,
heading "HuRef",
label "Alternate",
accession "GCF_000002125",
version 1,
comment {
{
type genomic,
label "chromosome Chromosome 5",
accession "AC_000137",
version 1,
seqs {
int {
from 135879842,
to 136037385,
strand plus,
id gi 157734151
}
}
}
}
},
{
type assembly,
heading "CHM1_1.0",
label "Alternate",
accession "GCF_000306695",
version 1,
comment {
{
type genomic,
label "chromosome Chromosome 5",
accession "NC_018916",
version 1,
seqs {
int {
from 141011444,
to 141169209,
strand plus,
id gi 409253459
}
}
}
}
}
}
},
{
type comment,
heading "Build 37.3",
comment {
{
type assembly,
heading "GRCh37.p5",
label "Reference",
accession "GCF_000001405",
version 17,
comment {
{
type assembly-unit,
heading "Primary Assembly",
accession "GCF_000001305",
version 13,
comment {
{
type genomic,
label "chromosome Chromosome 5",
accession "NC_000005",
version 9,
seqs {
int {
from 140734767,
to 140892545,
strand plus,
id gi 224589817
}
}
}
}
}
}
},
{
type assembly,
heading "HuRef",
label "Alternate",
accession "GCF_000002125",
version 1,
comment {
{
type assembly-unit,
heading "Primary Assembly",
accession "GCF_000000025",
version 1,
comment {
{
type genomic,
label "chromosome Chromosome 5",
accession "AC_000137",
version 1,
seqs {
int {
from 135879842,
to 136037385,
strand plus,
id gi 157734151
}
}
}
}
}
}
}
}
}
}
}
},
unique-keys {
{
db "HGNC",
tag id 8702
},
{
db "LocusID",
tag id 56111
},
{
db "MIM",
tag id 606291
}
},
xtra-index-terms {
"LOC56111"
}
}