BLASTP 2.0.14 [Jun-29-2000]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= CYS1_DICDI
(343 letters)
Database: /home/peter/blast/data/swissprot.pr
88,780 sequences; 31,984,247 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
sp|P04988|CYS1_DICDI CYSTEINE PROTEINASE 1 PRECURSOR 721 0.0
sp|P43295|A494_ARATH PROBABLE CYSTEINE PROTEINASE A494 PRECURSOR 281 1e-75
sp|P25804|CYSP_PEA CYSTEINE PROTEINASE 15A PRECURSOR (TURGOR-RES... 278 1e-74
sp|P43296|RD19_ARATH CYSTEINE PROTEINASE RD19A PRECURSOR 275 1e-73
sp|Q10716|CYS1_MAIZE CYSTEINE PROTEINASE 1 PRECURSOR 262 7e-70
sp|P04989|CYS2_DICDI CYSTEINE PROTEINASE 2 PRECURSOR (PRESTALK C... 262 7e-70
sp|P54640|CYS5_DICDI CYSTEINE PROTEINASE 5 PRECURSOR 249 7e-66
sp|Q26534|CATL_SCHMA CATHEPSIN L PRECURSOR (SMCL1) 244 2e-64
sp|P14658|CYSP_TRYBB CYSTEINE PROTEINASE PRECURSOR 243 4e-64
sp|P35591|CYS1_LEIPI CYSTEINE PROTEINASE 1 PRECURSOR (AMASTIGOTE... 236 5e-62
sp|P25775|LCPA_LEIME CYSTEINE PROTEINASE A PRECURSOR 235 9e-62
sp|P25779|CYSP_TRYCR CRUZIPAIN PRECURSOR (MAJOR CYSTEINE PROTEIN... 232 1e-60
sp|P13277|CYS1_HOMAM DIGESTIVE CYSTEINE PROTEINASE 1 PRECURSOR 225 1e-58
sp|P25782|CYS2_HOMAM DIGESTIVE CYSTEINE PROTEINASE 2 PRECURSOR 224 2e-58
sp|P07154|CATL_RAT CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN... 224 3e-58
sp|P06797|CATL_MOUSE CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTE... 223 5e-58
sp|P25784|CYS3_HOMAM DIGESTIVE CYSTEINE PROTEINASE 3 PRECURSOR 221 1e-57
sp|P41721|CATV_NPVBM VIRAL CATHEPSIN (V-CATH) 221 2e-57
sp|P41715|CATV_NPVCF VIRAL CATHEPSIN (V-CATH) 220 4e-57
sp|P25975|CATL_BOVIN CATHEPSIN L PRECURSOR 218 1e-56
sp|P36400|LCPB_LEIME CYSTEINE PROTEINASE B PRECURSOR 218 2e-56
sp|Q05094|CYS2_LEIPI CYSTEINE PROTEINASE 2 PRECURSOR (AMASTIGOTE... 218 2e-56
sp|P12412|CYSP_VIGMU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYS... 217 3e-56
sp|P07711|CATL_HUMAN CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTE... 215 8e-56
sp|Q28944|CATL_PIG CATHEPSIN L PRECURSOR 214 2e-55
sp|P25783|CATV_NPVAC VIRAL CATHEPSIN (V-CATH) 213 3e-55
sp|Q40143|CYS3_LYCES CYSTEINE PROTEINASE 3 PRECURSOR 212 7e-55
sp|O60911|CATM_HUMAN CATHEPSIN L2 PRECURSOR (CATHEPSIN V) 210 5e-54
sp|P54639|CYS4_DICDI CYSTEINE PROTEINASE 4 PRECURSOR 209 6e-54
sp|Q10991|CATL_SHEEP CATHEPSIN L 209 6e-54
sp|P25803|CYSP_PHAVU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYS... 208 2e-53
sp|P00785|ACTN_ACTCH ACTINIDAIN PRECURSOR (ACTINIDIN) 206 4e-53
sp|P43156|CYSP_HEMSP THIOL PROTEASE SEN102 PRECURSOR 203 6e-52
sp|P25777|ORYB_ORYSA ORYZAIN BETA CHAIN PRECURSOR 203 6e-52
sp|Q10717|CYS2_MAIZE CYSTEINE PROTEINASE 2 PRECURSOR 201 2e-51
sp|P00786|CATH_RAT CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPS... 200 3e-51
sp|O10364|CATV_NPVOP VIRAL CATHEPSIN (V-CATH) 199 9e-51
sp|P43297|RD21_ARATH CYSTEINE PROTEINASE RD21A PRECURSOR 198 2e-50
sp|P15242|TES1_RAT TESTIN 1/2 PRECURSOR (CMB-22/CMB-23) 198 2e-50
sp|P25776|ORYA_ORYSA ORYZAIN ALPHA CHAIN PRECURSOR 198 2e-50
sp|P14080|PAP2_CARPA CHYMOPAPAIN PRECURSOR (PAPAYA PROTEINASE II... 194 2e-49
sp|P43235|CATK_HUMAN CATHEPSIN K PRECURSOR (CATHEPSIN O) (CATHEP... 194 2e-49
sp|P25778|ORYC_ORYSA ORYZAIN GAMMA CHAIN PRECURSOR 194 3e-49
sp|P25251|CYS4_BRANA CYSTEINE PROTEINASE COT44 PRECURSOR 194 3e-49
sp|P09668|CATH_HUMAN CATHEPSIN H PRECURSOR 192 1e-48
sp|O46427|CATH_PIG CATHEPSIN H PRECURSOR 191 2e-48
sp|P05167|ALEU_HORVU THIOL PROTEASE ALEURAIN PRECURSOR 191 2e-48
sp|P43236|CATK_RABIT CATHEPSIN K PRECURSOR (OC-2 PROTEIN) 191 2e-48
sp|P10056|PAP3_CARPA CARICAIN PRECURSOR (PAPAYA PROTEINASE OMEGA... 190 3e-48
sp|P49935|CATH_MOUSE CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHE... 189 6e-48
sp|P55097|CATK_MOUSE CATHEPSIN K PRECURSOR 188 1e-47
sp|P56203|CATW_MOUSE CATHEPSIN W PRECURSOR (LYMPHOPAIN) 185 9e-47
sp|P25250|CYS2_HORVU CYSTEINE PROTEINASE EP-B 2 PRECURSOR 184 2e-46
sp|P25249|CYS1_HORVU CYSTEINE PROTEINASE EP-B 1 PRECURSOR 184 3e-46
sp|P05994|PAP4_CARPA PAPAYA PROTEINASE IV PRECURSOR (PPIV) (PAPA... 183 3e-46
sp|P22895|P34_SOYBN P34 PROBABLE THIOL PROTEASE PRECURSOR 183 3e-46
sp|P43234|CATO_HUMAN CATHEPSIN O PRECURSOR 182 8e-46
sp|P56202|CATW_HUMAN CATHEPSIN W PRECURSOR (LYMPHOPAIN) 182 1e-45
sp|P25774|CATS_HUMAN CATHEPSIN S PRECURSOR 177 3e-44
sp|P00784|PAPA_CARPA PAPAIN PRECURSOR (PAPAYA PROTEINASE I) (PPI) 176 6e-44
sp||CATL_CHICK_1 [Segment 1 of 2] CATHEPSIN L 175 1e-43
sp|P25326|CATS_BOVIN CATHEPSIN S 173 5e-43
sp|P80884|ANAN_ANACO ANANAIN 167 3e-41
sp|Q02765|CATS_RAT CATHEPSIN S PRECURSOR 167 4e-41
sp|P20721|CYSL_LYCES LOW-TEMPERATURE-INDUCED CYSTEINE PROTEINASE... 164 3e-40
sp|P36184|ACP1_ENTHI CYSTEINE PROTEINASE ACP1 PRECURSOR 162 7e-40
sp|O17473|CATL_BRUPA CATHEPSIN L-LIKE PRECURSOR 159 8e-39
sp|Q01957|CPP1_ENTHI CYSTEINE PROTEINASE 1 PRECURSOR 156 5e-38
sp|Q06964|CPP3_ENTHI CYSTEINE PROTEINASE 3 PRECURSOR (CYSTEINE P... 153 4e-37
sp|Q01958|CPP2_ENTHI CYSTEINE PROTEINASE 2 PRECURSOR 153 5e-37
sp|P46102|CYSP_PLAVN CYSTEINE PROTEINASE PRECURSOR 153 6e-37
sp|P36185|ACP2_ENTHI CYSTEINE PROTEINASE ACP2 PRECURSOR 150 5e-36
sp|P25781|CYSP_THEAN CYSTEINE PROTEINASE PRECURSOR 146 5e-35
sp|P14518|BROM_ANACO BROMELAIN, STEM 146 6e-35
sp|P22497|CYSP_THEPA CYSTEINE PROTEINASE PRECURSOR 145 1e-34
sp|P16311|MMAL_DERFA MAJOR MITE FECAL ALLERGEN DER F 1 PRECURSOR... 144 3e-34
sp|P25805|CYSP_PLAFA THROPHOZOITE CYSTEINE PROTEINASE PRECURSOR ... 144 3e-34
sp|P42666|CYSP_PLAVI CYSTEINE PROTEINASE PRECURSOR 132 1e-30
sp|P08176|MMAL_DERPT MAJOR MITE FECAL ALLERGEN DER P 1 PRECURSOR... 123 7e-28
sp|P80067|CATC_RAT DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPP... 117 3e-26
sp|P97821|CATC_MOUSE DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (D... 116 8e-26
sp|P53634|CATC_HUMAN DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (D... 113 4e-25
sp|Q26563|CATC_SCHMA CATHEPSIN C PRECURSOR 113 7e-25
sp|P25773|CATL_FELCA CATHEPSIN L (PROGESTERONE-DEPENDENT PROTEIN... 113 7e-25
sp|P25780|EUM1_EURMA MITE GROUP I ALLERGEN EUR M 1 (EUR M I) 105 1e-22
sp|Q23894|CYS3_DICDI CYSTEINE PROTEINASE 3 (CYSTEINE PROTEINASE II) 96 1e-19
sp|P43508|CPR4_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 4 PREC... 94 3e-19
sp|P05993|PAP5_CARPA CYSTEINE PROTEINASE (CLONE PLBPC13) 90 5e-18
sp|P25807|CYS1_CAEEL GUT-SPECIFIC CYSTEINE PROTEINASE PRECURSOR 90 5e-18
sp|P43509|CPR5_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 5 PREC... 89 1e-17
sp|P00787|CATB_RAT CATHEPSIN B PRECURSOR (CATHEPSIN B1) (RSG-2) 88 3e-17
sp|P07688|CATB_BOVIN CATHEPSIN B PRECURSOR 87 5e-17
sp|P07858|CATB_HUMAN CATHEPSIN B PRECURSOR (CATHEPSIN B1) (APP S... 86 1e-16
sp|P43157|CYSP_SCHJA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECUR... 85 3e-16
sp|P25792|CYSP_SCHMA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECUR... 85 3e-16
sp|P10605|CATB_MOUSE CATHEPSIN B PRECURSOR (CATHEPSIN B1) 84 5e-16
sp|P43510|CPR6_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6 PREC... 83 6e-16
sp|P43233|CATB_CHICK CATHEPSIN B PRECURSOR (CATHEPSIN B1) 83 6e-16
sp|P25802|CYS1_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PREC... 76 1e-13
sp|P25793|CYS2_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 2 PREC... 75 2e-13
sp|P19092|CYS1_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PREC... 75 3e-13
sp|P43507|CPR3_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3 PREC... 73 7e-13
sp|P13823|SERA_PLAFG SERINE-REPEAT ANTIGEN PROTEIN PRECURSOR (P1... 71 4e-12
sp|P32956|CC3_CARCN CYSTEINE PROTEINASE III (CC-III) 63 8e-10
sp|P32957|CC4_CARCN CYSTEINE PROTEINASE IV (CC-IV) 62 2e-09
sp|Q06544|CYS3_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3 59 1e-08
sp|P32954|CC1_CARCN CYSTEINE PROTEINASE I (CC-I) 59 2e-08
sp|P32955|CC2_CARCN CYSTEINE PROTEINASE II (CC-II) 58 3e-08
sp||CATL_CHICK_2 [Segment 2 of 2] CATHEPSIN L 52 2e-06
sp|P12399|CT2A_MOUSE CTLA-2-ALPHA PROTEIN PRECURSOR 42 0.002
sp|P21381|THPA_THADA THAUMATOPAIN 41 0.005
sp|P05689|CATX_BOVIN CATHEPSIN 40 0.006
sp|P12400|CT2B_MOUSE CTLA-2-BETA PROTEIN PRECURSOR 39 0.018
sp|P20736|BM86_BOOMI GLYCOPROTEIN ANTIGEN BM86 PRECURSOR (PROTEC... 35 0.21
sp|Q11121|PLB1_TORDE LYSOPHOSPHOLIPASE PRECURSOR (PHOSPHOLIPASE B) 35 0.27
sp|P46992|YJR1_YEAST HYPOTHETICAL 43.0 KD PROTEIN IN CPS1-FPP1 I... 34 0.61
sp|P28493|PR5_ARATH PATHOGENESIS-RELATED PROTEIN 5 PRECURSOR (PR-5) 32 1.8
sp|P41901|SPR3_YEAST SPORULATION-SPECIFIC SEPTIN 32 2.4
sp|P54634|POLN_LORDV NON-STRUCTURAL POLYPROTEIN [CONTAINS: RNA-D... 31 3.1
sp|P21173|DNAA_MICLU CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA 31 3.1
sp|P89263|Y022_GVXN HYPOTHETICAL ORF22 HOMOLOG 31 5.3
sp|P24896|NU5M_CAEEL NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 31 5.3
sp|P25648|SRB8_YEAST SUPPRESSOR OF RNA POLYMERASE B SRB8 30 7.0
sp|Q04723|PEPC_LACLC AMINOPEPTIDASE C 30 7.0
sp|Q13867|BLMH_HUMAN BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) 30 9.1
sp|P87362|BLMH_CHICK BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) (... 30 9.1
sp|P70645|BLMH_RAT BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) 30 9.1
>sp|P04988|CYS1_DICDI CYSTEINE PROTEINASE 1 PRECURSOR
Length = 343
Score = 721 bits (1841), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE
Sbjct: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPT 120
ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPT
Sbjct: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPT 120
Query: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY
Sbjct: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
Query: 181 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM 240
EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM
Sbjct: 181 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM 240
Query: 241 IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF 300
IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF
Sbjct: 241 IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF 300
Query: 301 RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII
Sbjct: 301 RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
>sp|P43295|A494_ARATH PROBABLE CYSTEINE PROTEINASE A494 PRECURSOR
Length = 313
Score = 281 bits (712), Expect = 1e-75
Identities = 147/316 (46%), Positives = 193/316 (60%), Gaps = 18/316 (5%)
Query: 32 FQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKA---DTKFGVNKFADLSSDE 87
F+ KF K Y S EE+ RF +FK+NL L A+ H+ + GV +F+DL+ E
Sbjct: 3 FKKKFGKVYGSIEEHYYRFSVFKANL-------LRAMRHQKMDPSARHGVTQFSDLTRSE 55
Query: 88 FKNYYLNNKEAI-FTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFS 146
F+ +L K D A L + ++P FDWR RGAVTPVKNQG CGSCWSFS
Sbjct: 56 FRRKHLGVKGGFKLPKDANQAPILPTQ---NLPEEFDWRDRGAVTPVKNQGSCGSCWSFS 112
Query: 147 TTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNG 206
TTG +EG HF++ KLVSLSEQ LVDCDHEC + E E +CD GCNGGL +A+ Y +K G
Sbjct: 113 TTGALEGAHFLATGKLVSLSEQQLVDCDHEC-DPEEEGSCDSGCNGGLMNSAFEYTLKTG 171
Query: 207 GIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVE 266
G+ E YPYT G C + + I A +SNF+++ NE +A ++ GPLA+A +A
Sbjct: 172 GLMREKDYPYTGTDGGSCKLDRSKIVASVSNFSVVSINEDQIAANLIKNGPLAVAINAAY 231
Query: 267 WQFYIGGVFDIPCNPNSLDHGILIVGYSAK--NTIFRKNMPYWIVKNSWGADWGEQGYIY 324
Q YIGGV L+HG+L+VGY + + K PYWI+KNSWG WGE G+
Sbjct: 232 MQTYIGGVSCPYICSRRLNHGVLLVGYGSAGFSQARLKEKPYWIIKNSWGESWGENGFYK 291
Query: 325 LRRGKNTCGVSNFVST 340
+ +G+N CGV + VST
Sbjct: 292 ICKGRNICGVDSLVST 307
>sp|P25804|CYSP_PEA CYSTEINE PROTEINASE 15A PRECURSOR (TURGOR-RESPONSIVE PROTEIN 15A)
Length = 363
Score = 278 bits (703), Expect = 1e-74
Identities = 144/320 (45%), Positives = 201/320 (62%), Gaps = 14/320 (4%)
Query: 26 QSQFLEFQDKFNKKYS-HEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
+ F F+ KF+K Y+ EE+ RF +FKSNL K + + N + G+ KF+DL+
Sbjct: 45 EHHFTSFKSKFSKSYATKEEHDYRFGVFKSNLIKAK----LHQNRDPTAEHGITKFSDLT 100
Query: 85 SDEFKNYYLNNKEAIFTDDLPV-ADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCW 143
+ EF+ +L K+ + LP A ++P FDWR +GAVTPVK+QG CGSCW
Sbjct: 101 ASEFRRQFLGLKKRL---RLPAHAQKAPILPTTNLPEDFDWREKGAVTPVKDQGSCGSCW 157
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+FSTTG +EG H+++ KLVSLSEQ LVDCDH C + E +CD GCNGGL NA+ Y++
Sbjct: 158 AFSTTGALEGAHYLATGKLVSLSEQQLVDCDHVC-DPEQAGSCDSGCNGGLMNNAFEYLL 216
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAAD 263
++GG+ E Y YT G+ C F+ + + A +SNF+++ +E +A +V GPLA+A +
Sbjct: 217 ESGGVVQEKDYAYTGRDGS-CKFDKSKVVASVSNFSVVTLDEDQIAANLVKNGPLAVAIN 275
Query: 264 AVEWQFYIGGV-FDIPCNPNSLDHGILIVGY--SAKNTIFRKNMPYWIVKNSWGADWGEQ 320
A Q Y+ GV C + LDHG+L+VG+ A I K PYWI+KNSWG +WGEQ
Sbjct: 276 AAWMQTYMSGVSCPYVCAKSRLDHGVLLVGFGKGAYAPIRLKEKPYWIIKNSWGQNWGEQ 335
Query: 321 GYIYLRRGKNTCGVSNFVST 340
GY + RG+N CGV + VST
Sbjct: 336 GYYKICRGRNVCGVDSMVST 355
>sp|P43296|RD19_ARATH CYSTEINE PROTEINASE RD19A PRECURSOR
Length = 368
Score = 275 bits (695), Expect = 1e-73
Identities = 155/359 (43%), Positives = 205/359 (56%), Gaps = 34/359 (9%)
Query: 6 LFVLAVFTVFVSSR---------------GIPPE---EQSQFLEFQDKFNKKY-SHEEYL 46
+FVL+ F V VSS G P+ + F F+ KF K Y S+EE+
Sbjct: 10 VFVLSFFIVSVSSSDVNDGDDLVIRQVVGGAEPQVLTSEDHFSLFKRKFGKVYASNEEHD 69
Query: 47 ERFEIFKSNLGKIEELNLIAINHKADTK--FGVNKFADLSSDEFKNYYLNNKEAI-FTDD 103
RF +FK+NL + + K D GV +F+DL+ EF+ +L + D
Sbjct: 70 YRFSVFKANLRRARR------HQKLDPSATHGVTQFSDLTRSEFRKKHLGVRSGFKLPKD 123
Query: 104 LPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLV 163
A L E ++P FDWR GAVTPVKNQG CGSCWSFS TG +EG +F++ KLV
Sbjct: 124 ANKAPILPTE---NLPEDFDWRDHGAVTPVKNQGSCGSCWSFSATGALEGANFLATGKLV 180
Query: 164 SLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ 223
SLSEQ LVDCDHEC + E ++CD GCNGGL +A+ Y +K GG+ E YPYT + G
Sbjct: 181 SLSEQQLVDCDHEC-DPEEADSCDSGCNGGLMNSAFEYTLKTGGLMKEEDYPYTGKDGKT 239
Query: 224 CNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNS 283
C + + I A +SNF++I +E +A +V GPLA+A +A Q YIGGV
Sbjct: 240 CKLDKSKIVASVSNFSVISIDEEQIAANLVKNGPLAVAINAGYMQTYIGGVSCPYICTRR 299
Query: 284 LDHGILIVGYSAKN--TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVST 340
L+HG+L+VGY A K PYWI+KNSWG WGE G+ + +G+N CGV + VST
Sbjct: 300 LNHGVLLVGYGAAGYAPARFKEKPYWIIKNSWGETWGENGFYKICKGRNICGVDSMVST 358
>sp|Q10716|CYS1_MAIZE CYSTEINE PROTEINASE 1 PRECURSOR
Length = 371
Score = 262 bits (663), Expect = 7e-70
Identities = 138/324 (42%), Positives = 189/324 (57%), Gaps = 15/324 (4%)
Query: 26 QSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
+S FL F +F K Y +E+ R +FK NL + L+ + GV KF+DL+
Sbjct: 45 ESHFLSFVQRFGKSYKDADEHAYRLSVFKDNLRRARRHQLL----DPSAEHGVTKFSDLT 100
Query: 85 SDEFKNYYLN---NKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGS 141
EF+ YL ++ A+ + A + +P FDWR GAV PVKNQG CGS
Sbjct: 101 PAEFRRTYLGLRKSRRALLRELGESAHEAPVLPTDGLPDDFDWRDHGAVGPVKNQGSCGS 160
Query: 142 CWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNY 201
CWSFS +G +EG H+++ KL LSEQ VDCDHEC E ++CD GCNGGL A++Y
Sbjct: 161 CWSFSASGALEGAHYLATGKLEVLSEQQFVDCDHECDSSE-PDSCDSGCNGGLMTTAFSY 219
Query: 202 IIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIA 261
+ K GG+++E YPYT G +C F+ + I A + NF+++ +E ++ ++ GPLAI
Sbjct: 220 LQKAGGLESEKDYPYTGSDG-KCKFDKSKIVASVQNFSVVSVDEAQISANLIKHGPLAIG 278
Query: 262 ADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN--TIFRKNMPYWIVKNSWGADWGE 319
+A Q YIGGV LDHG+L+VGY A I K+ PYWI+KNSWG +WGE
Sbjct: 279 INAAYMQTYIGGVSCPYICGRHLDHGVLLVGYGASGFAPIRLKDKPYWIIKNSWGENWGE 338
Query: 320 QGYIYLRRG---KNTCGVSNFVST 340
GY + RG +N CGV + VST
Sbjct: 339 NGYYKICRGSNVRNKCGVDSMVST 362
>sp|P04989|CYS2_DICDI CYSTEINE PROTEINASE 2 PRECURSOR (PRESTALK CATHEPSIN)
Length = 376
Score = 262 bits (663), Expect = 7e-70
Identities = 147/383 (38%), Positives = 213/383 (55%), Gaps = 55/383 (14%)
Query: 1 MKVILLFVLAVFTVFVSSRGIP-------PEEQSQFLEFQDKFNKKYSHEEYLERFEIFK 53
M++++ +L +F F + P + ++ F E+ KFN++YS E+ R+ IFK
Sbjct: 1 MRLLVFLILLIFVNFSFANVRPNGRRFSESQYRTAFTEWTLKFNRQYSSSEFSNRYSIFK 60
Query: 54 SNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNK-EAIFTDDLPVADYLDD 112
SN+ ++ N + T G+N FAD++++E++ YL + A + + L+
Sbjct: 61 SNMDYVDNWNS---KGDSQTVLGLNNFADITNEEYRKTYLGTRVNAHSYNGYDGREVLNV 117
Query: 113 EFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVD 172
E + + P + DWRT+ AVTP+K+QGQCGSCWSFSTTG+ EG H + KLVSLSEQNLVD
Sbjct: 118 EDLQTNPKSIDWRTKNAVTPIKDQGQCGSCWSFSTTGSTEGAHALKTKKLVSLSEQNLVD 177
Query: 173 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG 232
C G E + GC+GGL NA++YIIKN GI TESSYPYTAETG+ C FN ++IG
Sbjct: 178 C-------SGPEE-NFGCDGGLMNNAFDYIIKNKGIDTESSYPYTAETGSTCLFNKSDIG 229
Query: 233 AKISNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGIL 289
A I + I + GP+++A DA +Q Y G++ P C+P LDHG+L
Sbjct: 230 ATIKGYVNITAGSEISLENGAQHGPVSVAIDASHNSFQLYTSGIYYEPKCSPTELDHGVL 289
Query: 290 IVGY--------------------------------SAKNTIFRKNMPYWIVKNSWGADW 317
+VGY + +++ K YWIVKNSWG W
Sbjct: 290 VVGYGVQGKDDEGPVLNRKQTIVIHKNEDNKVESSDDSSDSVRPKANNYWIVKNSWGTSW 349
Query: 318 GEQGYIYLRRG-KNTCGVSNFVS 339
G +GYI + + KN CG+++ S
Sbjct: 350 GIKGYILMSKDRKNNCGIASVSS 372
>sp|P54640|CYS5_DICDI CYSTEINE PROTEINASE 5 PRECURSOR
Length = 344
Score = 249 bits (629), Expect = 7e-66
Identities = 139/362 (38%), Positives = 201/362 (55%), Gaps = 37/362 (10%)
Query: 1 MKVI-LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKI 59
MKV+ L VL V + + ++ F ++ K Y+ EE+ R+ IF +N+ +
Sbjct: 1 MKVLSFLCVLLVSVATAKQQFSELQYRNAFTDWMITHQKSYTSEEFGARYNIFTANMDYV 60
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
++ N + ++T G+N FAD++++E++N YL K F + + NS
Sbjct: 61 QQWN----SKGSETVLGLNNFADITNEEYRNTYLGTK---FDASSLIGTQEEKVHTNSSA 113
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
+ DWR+ GAVTPVKNQGQCG CWSFSTTG+ EG HF S+ +LVSLSEQNL+DC E
Sbjct: 114 ASKDWRSEGAVTPVKNQGQCGGCWSFSTTGSTEGAHFQSKGELVSLSEQNLIDCSTE--- 170
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
+ GC+GGL A+ YII N GI TESSYPY AE G +C + S N GA +S++
Sbjct: 171 -------NSGCDGGLMTYAFEYIINNNGIDTESSYPYKAENG-KCEYKSENSGATLSSYK 222
Query: 240 MIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGILIVGY--- 293
+ V+ P+++A DA +Q Y G++ P C+ +LDHG+L VGY
Sbjct: 223 TVTAGSESSLESAVNVNPVSVAIDASHQSFQLYTSGIYYEPECSSENLDHGVLAVGYGSG 282
Query: 294 -----------SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTS 341
S+ N + YWIVKNSWG WG +GYI + R + N CG+++ S
Sbjct: 283 SGSSSGQSSGQSSGNLSASSSNEYWIVKNSWGTSWGIEGYILMSRNRDNNCGIASSASFP 342
Query: 342 II 343
++
Sbjct: 343 VV 344
>sp|Q26534|CATL_SCHMA CATHEPSIN L PRECURSOR (SMCL1)
Length = 319
Score = 244 bits (617), Expect = 2e-64
Identities = 128/326 (39%), Positives = 190/326 (58%), Gaps = 22/326 (6%)
Query: 21 IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKF 80
+P ++++F+ K+ K+Y E RF IFKSN+ K + L + + +GV +
Sbjct: 12 LPGNVDEKYVQFKLKYRKQYHETEDEIRFNIFKSNILKAQ---LYQVFVRGSAIYGVTPY 68
Query: 81 ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCG 140
+DL++DEF +L + + L E +N+IP FDWR +GAVT VKNQG CG
Sbjct: 69 SDLTTDEFARTHLTASWVVPSSRSNTPTSLGKE-VNNIPKNFDWREKGAVTEVKNQGMCG 127
Query: 141 SCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYN 200
SCW+FSTTGNVE Q F KL+SLSEQ LVDCD D+GCNGGL NAY
Sbjct: 128 SCWAFSTTGNVESQWFRKTGKLLSLSEQQLVDCD----------GLDDGCNGGLPSNAYE 177
Query: 201 YIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAI 260
IIK GG+ E +YPY A+ +C+ + + I++ + ++ET +A ++ +++
Sbjct: 178 SIIKMGGLMLEDNYPYDAK-NEKCHLKTDGVAVYINSSVNLTQDETELAAWLYHNSTISV 236
Query: 261 AADAVEWQFYIGGV---FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 317
+A+ QFY G+ + I C+ LDH +L+VGY + KN P+WIVKNSWG +W
Sbjct: 237 GMNALLLQFYQHGISHPWWIFCSKYLLDHAVLLVGYG----VSEKNEPFWIVKNSWGVEW 292
Query: 318 GEQGYIYLRRGKNTCGVSNFVSTSII 343
GE GY + RG +CG++ ++++I
Sbjct: 293 GENGYFRMYRGDGSCGINTVATSAMI 318
>sp|P14658|CYSP_TRYBB CYSTEINE PROTEINASE PRECURSOR
Length = 450
Score = 243 bits (614), Expect = 4e-64
Identities = 136/346 (39%), Positives = 193/346 (55%), Gaps = 26/346 (7%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEE 61
V+L + +V + S + + +F F+ K+ K Y +E RF F+ N+ E+
Sbjct: 15 VLLAMAACLASVALGSLHVEESLEMRFAAFKKKYGKVYKDAKEEAFRFRAFEENM---EQ 71
Query: 62 LNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTA 121
+ A + T FGV F+D++ +EF+ Y N + ++ P A
Sbjct: 72 AKIQAAANPYAT-FGVTPFSDMTREEFRARYRNGASYFAAAQKRLRKTVNVT-TGRAPAA 129
Query: 122 FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYE 181
DWR +GAVTPVK QGQCGSCW+FST GN+EGQ ++ N LVSLSEQ LV CD
Sbjct: 130 VDWREKGAVTPVKVQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCD------- 182
Query: 182 GEEACDEGCNGGLQPNAYNYIIKN--GGIQTESSYPYTAETG--TQCNFNSANIGAKISN 237
D GCNGGL NA+N+I+ + G + TE+SYPY + G QC N IGA I++
Sbjct: 183 ---TIDSGCNGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITD 239
Query: 238 FTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN 297
+P++E +A Y+ GPLAIA DA + Y GG+ C LDHG+L+VGY+ +
Sbjct: 240 HVDLPQDEDAIAAYLAENGPLAIAVDAESFMDYNGGIL-TSCTSKQLDHGVLLVGYNDNS 298
Query: 298 TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
N PYWI+KNSW WGE GYI + +G N C ++ VS++++
Sbjct: 299 -----NPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAVV 339
>sp|P35591|CYS1_LEIPI CYSTEINE PROTEINASE 1 PRECURSOR (AMASTIGOTE CYSTEINE PROTEINASE
A-1)
Length = 354
Score = 236 bits (596), Expect = 5e-62
Identities = 146/350 (41%), Positives = 196/350 (55%), Gaps = 38/350 (10%)
Query: 5 LLFVLAVFTVFVSSRGI-------PPEEQ----SQFLEFQDKFNKKYSHE-EYLERFEIF 52
LLF + V +FV G PP + + + F+ + K + + E RF F
Sbjct: 7 LLFAIVVTILFVVCYGSALIAQTPPPVDNFVASAHYGSFKKRHGKAFGGDAEEGHRFNAF 66
Query: 53 KSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLN-NKEAIFTDDLPVADYLD 111
K N+ LN + D KFADL+ EF YLN + A D ++D
Sbjct: 67 KQNMQTAYFLNTQNPHAHYDVS---GKFADLTPQEFAKLYLNPDYYARHLKDHKEDVHVD 123
Query: 112 DEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLV 171
D + + + DWR +GAVTPVKNQG CGSCW+FS GN+EGQ S + LVSLSEQ LV
Sbjct: 124 DSAPSGVMSV-DWRDKGAVTPVKNQGLCGSCWAFSAIGNIEGQWAASGHSLVSLSEQMLV 182
Query: 172 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETGTQ--CNFN 227
CD+ DEGCNGGL A N+I++ NG + TE+SYPYT+ GT+ C+ +
Sbjct: 183 SCDN----------IDEGCNGGLMDQAMNWIMQSHNGSVFTEASYPYTSGGGTRPPCH-D 231
Query: 228 SANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHG 287
+GAKI+ F +P +E +A ++ GP+A+A DA WQ Y GGV + C SL+HG
Sbjct: 232 EGEVGAKITGFLSLPHDEERIAEWVEKRGPVAVAVDATTWQLYFGGVVSL-CLAWSLNHG 290
Query: 288 ILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNF 337
+LIVG++ KN PYWIVKNSWG+ WGE+GYI L G N C + N+
Sbjct: 291 VLIVGFN-KNA----KPPYWIVKNSWGSSWGEKGYIRLAMGSNQCMLKNY 335
>sp|P25775|LCPA_LEIME CYSTEINE PROTEINASE A PRECURSOR
Length = 354
Score = 235 bits (594), Expect = 9e-62
Identities = 146/359 (40%), Positives = 195/359 (53%), Gaps = 56/359 (15%)
Query: 5 LLFVLAVFTVFVSSRGI-------PPEEQ----SQFLEFQDKFNKKYSHE-EYLERFEIF 52
LLF + V +FV G PP + + + F+ + K + + E RF F
Sbjct: 7 LLFAIVVTILFVVCYGSALIAQTPPPVDNFVASAHYGSFKKRHGKAFGGDAEEGHRFNAF 66
Query: 53 KSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLN----------NKEAIFTD 102
K N+ LN + D KFADL+ EF YLN +KE + D
Sbjct: 67 KQNMQTAYFLNTQNPHAHYDVS---GKFADLTPQEFAKLYLNPDYYARHLKNHKEDVHVD 123
Query: 103 DLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKL 162
D + + + DWR +GAVTPVKNQG CGSCW+FS GN+EGQ S + L
Sbjct: 124 DSAPSGVM----------SVDWRDKGAVTPVKNQGLCGSCWAFSAIGNIEGQWAASGHSL 173
Query: 163 VSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAET 220
VSLSEQ LV CD+ DEGCNGGL A N+I++ NG + TE+SYPYT+
Sbjct: 174 VSLSEQMLVSCDN----------IDEGCNGGLMDQAMNWIMQSHNGSVFTEASYPYTSGG 223
Query: 221 GTQ--CNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIP 278
GT+ C+ + +GAKI+ F +P +E +A ++ GP+A+A DA WQ Y GGV +
Sbjct: 224 GTRPPCH-DEGEVGAKITGFLSLPHDEERIAEWVEKRGPVAVAVDATTWQLYFGGVVSL- 281
Query: 279 CNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNF 337
C SL+HG+LIVG++ KN PYWIVKNSWG+ WGE+GYI L G N C + N+
Sbjct: 282 CLAWSLNHGVLIVGFN-KNA----KPPYWIVKNSWGSSWGEKGYIRLAMGSNQCMLKNY 335
>sp|P25779|CYSP_TRYCR CRUZIPAIN PRECURSOR (MAJOR CYSTEINE PROTEINASE) (CRUZAINE)
Length = 467
Score = 232 bits (585), Expect = 1e-60
Identities = 137/350 (39%), Positives = 191/350 (54%), Gaps = 30/350 (8%)
Query: 3 VILLFVLAVFTVFV--SSRGIPPEEQ--SQFLEFQDKFNKKY-SHEEYLERFEIFKSNLG 57
++L VL V V ++ + EE SQF EF+ K + Y S E R +F+ NL
Sbjct: 8 LLLAAVLVVMACLVPAATASLHAEETLTSQFAEFKQKHGRVYESAAEEAFRLSVFRENLF 67
Query: 58 KIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINS 117
+ L+ A H FGV F+DL+ +EF++ Y +N A F A +
Sbjct: 68 -LARLHAAANPHAT---FGVTPFSDLTREEFRSRY-HNGAAHFAAAQERARVPVKVEVVG 122
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
P A DWR RGAVT VK+QGQCGSCW+FS GNVE Q F++ + L +LSEQ LV CD
Sbjct: 123 APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCD--- 179
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETGTQ--CNFNSANIGA 233
D GC+GGL NA+ +I++ NG + TE SYPY + G C + +GA
Sbjct: 180 -------KTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGA 232
Query: 234 KISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGY 293
I+ +P++E +A ++ GP+A+A DA W Y GGV C LDHG+L+VGY
Sbjct: 233 TITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVM-TSCVSEQLDHGVLLVGY 291
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
+ + PYWI+KNSW WGE+GYI + +G N C V S++++
Sbjct: 292 NDSAAV-----PYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVV 336
>sp|P13277|CYS1_HOMAM DIGESTIVE CYSTEINE PROTEINASE 1 PRECURSOR
Length = 322
Score = 225 bits (567), Expect = 1e-58
Identities = 130/341 (38%), Positives = 182/341 (53%), Gaps = 33/341 (9%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKI 59
MKV+ LF+ + + + EF+ KF +KY EE R +F NL I
Sbjct: 1 MKVVALFLFGLALAAANP---------SWEEFKGKFGRKYVDLEEERYRLNVFLDNLQYI 51
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
EE N + +N+F+D+++++F K+ P A + +
Sbjct: 52 EEFNKKYERGEVTYNLAINQFSDMTNEKFNAVMKGYKKG----PRPAAVFTSTDAAPE-S 106
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
T DWRT+GAVTPVK+QGQCGSCW+FSTTG +EGQHF+ +LVSLSEQ LVDC
Sbjct: 107 TEVDWRTKGAVTPVKDQGQCGSCWAFSTTGGIEGQHFLKTGRLVSLSEQQLVDC------ 160
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
G ++GCNGG A Y+ NGG+ TESSYPY A T C FNS IGA + +
Sbjct: 161 -AGGSYYNQGCNGGWVERAIMYVRDNGGVDTESSYPYEARDNT-CRFNSNTIGATCTGYV 218
Query: 240 MIPK-NETVMAGYIVSTGPLAIAADAVEWQF---YIGGVFDIPCNPNSLDHGILIVGYSA 295
I + +E+ + GP+++A DA F Y G ++ C+ + LDH +L VGY +
Sbjct: 219 GIAQGSESALKTATRDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGS 278
Query: 296 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVS 335
+ +W+VKNSW WGE GYI + R + N CG++
Sbjct: 279 EG-----GQDFWLVKNSWATSWGESGYIKMARNRNNNCGIA 314
>sp|P25782|CYS2_HOMAM DIGESTIVE CYSTEINE PROTEINASE 2 PRECURSOR
Length = 323
Score = 224 bits (566), Expect = 2e-58
Identities = 132/349 (37%), Positives = 188/349 (53%), Gaps = 32/349 (9%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKI 59
MKV +LF+ V S + F+ K+ ++Y EE R IF+ N I
Sbjct: 1 MKVAVLFLCGVALAAASP---------SWEHFKGKYGRQYVDAEEDSYRRVIFEQNQKYI 51
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
EE N N + +NKF D++ +EF N I PV+ + +
Sbjct: 52 EEFNKKYENGEVTFNLAMNKFGDMTLEEFNAVMKGN---IPRRSAPVSVFYPKKETGPQA 108
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
T DWRT+GAVTPVK+QGQCGSCW+FSTTG++EGQHF+ L+SL+EQ LVDC
Sbjct: 109 TEVDWRTKGAVTPVKDQGQCGSCWAFSTTGSLEGQHFLKTGSLISLAEQQLVDC------ 162
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
+GCNGG +A++YI N GI TE++YPY A G+ C F+S ++ A S T
Sbjct: 163 --SRPYGPQGCNGGWMNDAFDYIKANNGIDTEAAYPYEARDGS-CRFDSNSVAATCSGHT 219
Query: 240 MIPK-NETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGYSA 295
I +ET + + GP+++ DA +QFY GV+ P C+P+ LDH +L VGY +
Sbjct: 220 NIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGS 279
Query: 296 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 343
+ +W+VKNSW WG+ GYI + R + N CG++ S ++
Sbjct: 280 EG-----GQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323
>sp|P07154|CATL_RAT CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP) (CYCLIC
PROTEIN-2) (CP-2)
Length = 334
Score = 224 bits (564), Expect = 3e-58
Identities = 127/351 (36%), Positives = 195/351 (55%), Gaps = 31/351 (8%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEEL 62
++LL VL + T + + +Q+ +++ + Y E R +++ N+ I+
Sbjct: 4 LLLLAVLCLGTALATPK-FDQTFNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQLH 62
Query: 63 NLIAINHKADTKFGVNKFADLSSDEFKN------YYLNNKEAIFTDDLPVADYLDDEFIN 116
N N K +N F D++++EF+ + + K +F + L +
Sbjct: 63 NGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKHKKGRLFQEPLML---------- 112
Query: 117 SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
IP DWR +G VTPVKNQGQCGSCW+FS +G +EGQ F+ KL+SLSEQNLVDC H+
Sbjct: 113 QIPKTVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHD 172
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
+G ++GCNGGL A+ YI +NGG+ +E SYPY A+ G+ C + + A +
Sbjct: 173 ----QG----NQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGS-CKYRAEYAVANDT 223
Query: 237 NFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGILIVGY 293
F IP+ E + + + GP+++A DA QFY G++ P C+ LDHG+L+VGY
Sbjct: 224 GFVDIPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGY 283
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVSTSII 343
+ T K+ YW+VKNSWG +WG GYI + + +N CG++ S I+
Sbjct: 284 GYEGTDSNKD-KYWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333
>sp|P06797|CATL_MOUSE CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP)
Length = 334
Score = 223 bits (562), Expect = 5e-58
Identities = 126/351 (35%), Positives = 198/351 (55%), Gaps = 31/351 (8%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEEL 62
++LL VL + T + + +++ +++ + Y E R I++ N+ I+
Sbjct: 4 LLLLAVLCLGTALATPK-FDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLH 62
Query: 63 NLIAINHKADTKFGVNKFADLSSDEFKN------YYLNNKEAIFTDDLPVADYLDDEFIN 116
N N + +N F D++++EF+ + + K +F + L +
Sbjct: 63 NGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLML---------- 112
Query: 117 SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
IP + DWR +G VTPVKNQGQCGSCW+FS +G +EGQ F+ KL+SLSEQNLVDC H
Sbjct: 113 KIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHA 172
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
+G ++GCNGGL A+ YI +NGG+ +E SYPY A+ G+ C + + A +
Sbjct: 173 ----QG----NQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGS-CKYRAEFAVANDT 223
Query: 237 NFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGILIVGY 293
F IP+ E + + + GP+++A DA QFY G++ P C+ +LDHG+L+VGY
Sbjct: 224 GFVDIPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGY 283
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 343
+ T KN YW+VKNSWG++WG +GYI + + + N CG++ S ++
Sbjct: 284 GYEGTDSNKN-KYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333
>sp|P25784|CYS3_HOMAM DIGESTIVE CYSTEINE PROTEINASE 3 PRECURSOR
Length = 321
Score = 221 bits (558), Expect = 1e-57
Identities = 123/317 (38%), Positives = 182/317 (56%), Gaps = 37/317 (11%)
Query: 32 FQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEF-- 88
F+ ++ +KY +E L R +F+ N IE+ N N + K +N+F D++++EF
Sbjct: 23 FKTQYGRKYGDAKEELYRQRVFQQNEQLIEDFNKKFENGEVTFKVAMNQFGDMTNEEFNA 82
Query: 89 --KNYYLNNK---EAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCW 143
K Y ++ +A+FT + + DWRT+ VTPVK+Q QCGSCW
Sbjct: 83 VMKGYKKGSRGEPKAVFTAEA-----------GPMAADVDWRTKALVTPVKDQEQCGSCW 131
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+FS TG +EGQHF+ ++LVSLSEQ LVDC + ++GC GG +A++YI
Sbjct: 132 AFSATGALEGQHFLKNDELVSLSEQQLVDC--------STDYGNDGCGGGWMTSAFDYIK 183
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAAD 263
NGGI TESSYPY AE C F++ +IGA + + E + + GP+++A D
Sbjct: 184 DNGGIDTESSYPYEAE-DRSCRFDANSIGAICTGSVEVQHTEEALQEAVSGVGPISVAID 242
Query: 264 A--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQ 320
A +QFY GV ++ C+P LDHG+L VGY ++T YW+VKNSWG+ WG+
Sbjct: 243 ASHFSFQFYSSGVYYEQNCSPTFLDHGVLAVGYGTEST-----KDYWLVKNSWGSSWGDA 297
Query: 321 GYIYLRRGK-NTCGVSN 336
GYI + R + N CG+++
Sbjct: 298 GYIKMSRNRDNNCGIAS 314
>sp|P41721|CATV_NPVBM VIRAL CATHEPSIN (V-CATH)
Length = 323
Score = 221 bits (557), Expect = 2e-57
Identities = 131/342 (38%), Positives = 181/342 (52%), Gaps = 26/342 (7%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELN 63
+LF L V+ V S+ P + + F EF +FNK YS E E L RF+IF+ NL +I
Sbjct: 4 ILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEI---- 59
Query: 64 LIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD 123
I N K+ +NKF+DLS DE Y T + LD P FD
Sbjct: 60 -INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQP-PGKGPLEFD 117
Query: 124 WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE 183
WR VT VKNQG CG+CW+F+T G++E Q I N+L++LSEQ ++DCD
Sbjct: 118 WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDF-------- 169
Query: 184 EACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN-FTMIP 242
D GCNGGL A+ IIK GG+Q ES YPY A+ C NS ++ + + I
Sbjct: 170 --VDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEAD-NNNCRMNSNKFLVQVKDCYRYII 226
Query: 243 KNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRK 302
E + + GP+ +A DA + Y G+ C + L+H +L+VGY +N
Sbjct: 227 VYEEKLKDLLPLVGPIPMAIDAADIVNYKQGIIKY-CFDSGLNHAVLLVGYGVEN----- 280
Query: 303 NMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN-FVSTSII 343
N+PYW KN+WG DWGE G+ +++ N CG+ N ST++I
Sbjct: 281 NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 322
>sp|P41715|CATV_NPVCF VIRAL CATHEPSIN (V-CATH)
Length = 324
Score = 220 bits (554), Expect = 4e-57
Identities = 131/344 (38%), Positives = 188/344 (54%), Gaps = 27/344 (7%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKI 59
M I+L++L V ++ + + + F +F KFNK YS E E L RF+IF+ NL +I
Sbjct: 1 MNKIVLYLLVYGAVQCAAYDVL-KAPNYFEDFLHKFNKSYSSESEKLRRFQIFRHNLEEI 59
Query: 60 EELNLIAINHKADT-KFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSI 118
I NH T ++ +NKFADLS DE + Y + T + LD +
Sbjct: 60 -----INKNHNDSTAQYEINKFADLSKDETISKYTGLSLPLQTQNFCEVVVLDRP-PDKG 113
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECM 178
P FDWR VT VKNQG CG+CW+F+T G++E Q I N+ ++LSEQ L+DCD
Sbjct: 114 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNQFINLSEQQLIDCDF--- 170
Query: 179 EYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN- 237
D GC+GGL A+ ++ GGIQ ES YPY A G C N+A K+
Sbjct: 171 -------VDAGCDGGLLHTAFEAVMNMGGIQAESDYPYEANNG-DCRANAAKFVVKVKKC 222
Query: 238 FTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN 297
+ I E + + S GP+ +A DA + Y G+ C + L+H +L+VGY+ +N
Sbjct: 223 YRYITVFEEKLKDLLRSVGPIPVAIDASDIVNYKRGIMKY-CANHGLNHAVLLVGYAVEN 281
Query: 298 TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
+P+WI+KN+WGADWGEQGY +++ N CG+ N + +S
Sbjct: 282 -----GVPFWILKNTWGADWGEQGYFRVQQNINACGIQNELPSS 320
>sp|P25975|CATL_BOVIN CATHEPSIN L PRECURSOR
Length = 334
Score = 218 bits (550), Expect = 1e-56
Identities = 124/342 (36%), Positives = 182/342 (52%), Gaps = 25/342 (7%)
Query: 7 FVLAVFTVFVSSRG--IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNL 64
F L V + V+S + P + + +++ + Y E R +++ N I+ N
Sbjct: 5 FFLTVLCLGVASAAPKLDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQ 64
Query: 65 IAINHKADTKFGVNKFADLSSDEFK---NYYLNNKEAIFTDDLPVADYLDDEFINSIPTA 121
K + +N F D++++EF+ N + N K + + +P +
Sbjct: 65 EYSEGKHAFRMAMNAFGDMTNEEFRQVMNGFQNQKHK-------KGKLFHEPLLVDVPKS 117
Query: 122 FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYE 181
DW +G VTPVKNQGQCGSCW+FS TG +EGQ F KLVSLSEQNLVDC +
Sbjct: 118 VDWTKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRA----Q 173
Query: 182 GEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMI 241
G ++GCNGGL NA+ YI NGG+ +E SYPY A CN+ A + F I
Sbjct: 174 G----NQGCNGGLMDNAFQYIKDNGGLDSEESYPYLATDTNSCNYKPECSAANDTGFVDI 229
Query: 242 PKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNT 298
P+ E + + + GP+++A DA +QFY G+ +D C+ LDHG+L+VGY + T
Sbjct: 230 PQREKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGT 289
Query: 299 IFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVS 339
N +WIVKNSWG +WG GY+ + + +N CG++ S
Sbjct: 290 DSNNN-KFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAAS 330
>sp|P36400|LCPB_LEIME CYSTEINE PROTEINASE B PRECURSOR
Length = 443
Score = 218 bits (549), Expect = 2e-56
Identities = 123/320 (38%), Positives = 177/320 (54%), Gaps = 34/320 (10%)
Query: 29 FLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKA---DTKFGVNKFADLS 84
F EF+ + + Y E +R F+ NL + E H+A +FG+ KF DLS
Sbjct: 38 FEEFKRTYGRAYETLAEEQQRLANFERNLELMRE-------HQARNPHAQFGITKFFDLS 90
Query: 85 SDEFKNYYLNNKEAIFTDDLPVADYLDDEF--INSIPTAFDWRTRGAVTPVKNQGQCGSC 142
EF YLN A + ++++P A DWR +GAVTPVK+QG CGSC
Sbjct: 91 EAEFAARYLNGAAYFAAAKRHAAQHYRKARADLSAVPDAVDWREKGAVTPVKDQGACGSC 150
Query: 143 WSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYI 202
W+FS GN+EGQ +++ ++LVSLSEQ LV CD ++GC+GGL A++++
Sbjct: 151 WAFSAVGNIEGQWYLAGHELVSLSEQQLVSCDD----------MNDGCDGGLMLQAFDWL 200
Query: 203 IK--NGGIQTESSYPYTAETG--TQC-NFNSANIGAKISNFTMIPKNETVMAGYIVSTGP 257
++ NG + TE SYPY + G +C N + +GA+I +I +E MA ++ GP
Sbjct: 201 LQNTNGHLHTEDSYPYVSGNGYVPECSNSSELVVGAQIDGHVLIGSSEKAMAAWLAKNGP 260
Query: 258 LAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 317
+AIA DA + Y GV C L+HG+L+VGY + PYW++KNSWG DW
Sbjct: 261 IAIALDASSFMSYKSGVL-TACIGKQLNHGVLLVGYDMTGEV-----PYWVIKNSWGGDW 314
Query: 318 GEQGYIYLRRGKNTCGVSNF 337
GEQGY+ + G N C +S +
Sbjct: 315 GEQGYVRVVMGVNACLLSEY 334
>sp|Q05094|CYS2_LEIPI CYSTEINE PROTEINASE 2 PRECURSOR (AMASTIGOTE CYSTEINE PROTEINASE
A-2)
Length = 444
Score = 218 bits (549), Expect = 2e-56
Identities = 123/321 (38%), Positives = 178/321 (55%), Gaps = 35/321 (10%)
Query: 29 FLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKA---DTKFGVNKFADLS 84
F EF+ + + Y E +R F+ NL + E H+A +FG+ KF DLS
Sbjct: 38 FEEFKRTYGRAYETLAEEQQRLANFERNLELMRE-------HQARNPHAQFGITKFFDLS 90
Query: 85 SDEFKNYYLNNKEAIFTDDLPVADYLDDEF--INSIPTAFDWRTRGAVTPVKNQGQCGSC 142
EF YLN A + ++++P A DWR +GAVTPVK+QG CGSC
Sbjct: 91 EAEFAARYLNGAAYFAAAKRHAAQHYRKARADLSAVPDAVDWREKGAVTPVKDQGACGSC 150
Query: 143 WSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYI 202
W+FS GN+EGQ +++ ++LVSLSEQ LV CD ++GC+GGL A++++
Sbjct: 151 WAFSAVGNIEGQWYLAGHELVSLSEQQLVSCDD----------MNDGCDGGLMLQAFDWL 200
Query: 203 IK--NGGIQTESSYPYTAETG--TQCNFNSAN--IGAKISNFTMIPKNETVMAGYIVSTG 256
++ NG + TE SYPY + G +C+ +S +GA+I +I +E MA ++ G
Sbjct: 201 LQNTNGHLHTEDSYPYVSGNGYVPECSNSSEELVVGAQIDGHVLIGSSEKAMAAWLAKNG 260
Query: 257 PLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGAD 316
P+AIA DA + Y GV C L+HG+L+VGY + PYW++KNSWG D
Sbjct: 261 PIAIALDASSFMSYKSGVL-TACIGKQLNHGVLLVGYDMTGEV-----PYWVIKNSWGGD 314
Query: 317 WGEQGYIYLRRGKNTCGVSNF 337
WGEQGY+ + G N C +S +
Sbjct: 315 WGEQGYVRVVMGVNACLLSEY 335
>sp|P12412|CYSP_VIGMU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYSTEINE PROTEINASE)
(SULFHYDRYL-ENDOPEPTIDASE) (SH-EP)
Length = 362
Score = 217 bits (547), Expect = 3e-56
Identities = 127/306 (41%), Positives = 179/306 (57%), Gaps = 29/306 (9%)
Query: 47 ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNK---EAIFTDD 103
+RF +FK+N+ + N + +K +NKFAD+++ EF++ Y +K +F
Sbjct: 58 KRFNVFKANVMHVHNTNKMDKPYKLK----LNKFADMTNHEFRSTYAGSKVNHHKMFRGS 113
Query: 104 LPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLV 163
+ E + S+P + DWR +GAVT VK+QGQCGSCW+FST VEG + I NKLV
Sbjct: 114 QHGSGTFMYEKVGSVPASVDWRKKGAVTDVKDQGQCGSCWAFSTIVAVEGINQIKTNKLV 173
Query: 164 SLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ 223
SLSEQ LVDCD E ++GCNGGL +A+ +I + GGI TES+YPYTA+ GT
Sbjct: 174 SLSEQELVDCDKE---------ENQGCNGGLMESAFEFIKQKGGITTESNYPYTAQEGT- 223
Query: 224 CNFNSAN-IGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCN 280
C+ + N + I +P N+ V+ P+++A DA ++QFY GVF CN
Sbjct: 224 CDESKVNDLAVSIDGHENVPVNDENALLKAVANQPVSVAIDAGGSDFQFYSEGVFTGDCN 283
Query: 281 PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVSN 336
L+HG+ IVGY T+ N YWIV+NSWG +WGEQGYI ++R + CG++
Sbjct: 284 -TDLNHGVAIVGYG--TTVDGTN--YWIVRNSWGPEWGEQGYIRMQRNISKKEGLCGIAM 338
Query: 337 FVSTSI 342
S I
Sbjct: 339 MASYPI 344
>sp|P07711|CATL_HUMAN CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP)
Length = 333
Score = 215 bits (543), Expect = 8e-56
Identities = 124/341 (36%), Positives = 186/341 (54%), Gaps = 26/341 (7%)
Query: 8 VLAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLI 65
+LA F + ++S + + ++Q+ +++ N+ Y E R +++ N+ IE N
Sbjct: 6 ILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQE 65
Query: 66 AINHKADTKFGVNKFADLSSDEFK---NYYLNNKEAIFTDDLPVADYLDDEFINSIPTAF 122
K +N F D++S+EF+ N + N K + P +
Sbjct: 66 YREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPR-------KGKVFQEPLFYEAPRSV 118
Query: 123 DWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEG 182
DWR +G VTPVKNQGQCGSCW+FS TG +EGQ F +L+SLSEQNLVDC G
Sbjct: 119 DWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDC-------SG 171
Query: 183 EEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP 242
+ +EGCNGGL A+ Y+ NGG+ +E SYPY A T C +N A + F IP
Sbjct: 172 PQG-NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEA-TEESCKYNPKYSVANDTGFVDIP 229
Query: 243 KNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTI 299
K E + + + GP+++A DA + FY G+ F+ C+ +DHG+L+VGY ++T
Sbjct: 230 KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST- 288
Query: 300 FRKNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVS 339
N YW+VKNSWG +WG GY+ + + +N CG+++ S
Sbjct: 289 ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAAS 329
>sp|Q28944|CATL_PIG CATHEPSIN L PRECURSOR
Length = 334
Score = 214 bits (540), Expect = 2e-55
Identities = 117/307 (38%), Positives = 165/307 (53%), Gaps = 23/307 (7%)
Query: 40 YSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFK---NYYLNNK 96
Y E R +++ N+ IE N K +N F D++++EF+ N + N K
Sbjct: 40 YGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQK 99
Query: 97 EAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHF 156
+ + +P + DWR +G VT VKNQGQCGSCW+FS TG +EGQ F
Sbjct: 100 HK-------KGKVFHESLVLEVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQMF 152
Query: 157 ISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPY 216
KLVSLSEQNLVDC +G ++GCNGGL NA+ Y+ NGG+ TE SYPY
Sbjct: 153 RKTGKLVSLSEQNLVDCSRP----QG----NQGCNGGLMDNAFQYVKDNGGLDTEESYPY 204
Query: 217 TAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV 274
C + A + F IP+ E + + + GP+++A DA +QFY G+
Sbjct: 205 LGRETNSCTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGI 264
Query: 275 -FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-C 332
+D C+ LDHG+L+VGY + T + +WIVKNSWG +WG GY+ + + +N C
Sbjct: 265 YYDPDCSSKDLDHGVLVVGYGFEGT-DSNSSKFWIVKNSWGPEWGWNGYVKMAKDQNNHC 323
Query: 333 GVSNFVS 339
G+S S
Sbjct: 324 GISTAAS 330
>sp|P25783|CATV_NPVAC VIRAL CATHEPSIN (V-CATH)
Length = 323
Score = 213 bits (538), Expect = 3e-55
Identities = 129/342 (37%), Positives = 179/342 (51%), Gaps = 26/342 (7%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELN 63
+LF L V+ V S+ + + F EF +FNK Y E E L RF+IF+ NL +I
Sbjct: 4 ILFYLFVYGVVNSAAYDLLKAPNYFEEFVHRFNKDYGSEVEKLRRFKIFQHNLNEI---- 59
Query: 64 LIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD 123
I N K+ +NKF+DLS DE Y I T + LD P FD
Sbjct: 60 -INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPIQTQNFCKVIVLDQP-PGKGPLEFD 117
Query: 124 WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE 183
WR VT VKNQG CG+CW+F+T ++E Q I N+L++LSEQ ++DCD
Sbjct: 118 WRRLNKVTSVKNQGMCGACWAFATLASLESQFAIKHNQLINLSEQQMIDCDF-------- 169
Query: 184 EACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN-FTMIP 242
D GCNGGL A+ IIK GG+Q ES YPY A+ C NS ++ + + I
Sbjct: 170 --VDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEAD-NNNCRMNSNKFLVQVKDCYRYIT 226
Query: 243 KNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRK 302
E + + GP+ +A DA + Y G+ C + L+H +L+VGY +N
Sbjct: 227 VYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIKY-CFNSGLNHAVLLVGYGVEN----- 280
Query: 303 NMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN-FVSTSII 343
N+PYW KN+WG DWGE G+ +++ N CG+ N ST++I
Sbjct: 281 NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 322
>sp|Q40143|CYS3_LYCES CYSTEINE PROTEINASE 3 PRECURSOR
Length = 356
Score = 212 bits (535), Expect = 7e-55
Identities = 126/324 (38%), Positives = 176/324 (53%), Gaps = 34/324 (10%)
Query: 29 FLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
F F + K+Y S EE +RFEIF NL I N +++K G+N+F DL+ DE
Sbjct: 57 FARFAIRHRKRYDSVEEIKQRFEIFLDNLKMIRSHNRKGLSYK----LGINEFTDLTWDE 112
Query: 88 FKNYYLN---NKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWS 144
F+ + L N A +L + + + +P DWR G V+PVK QG+CGSCW+
Sbjct: 113 FRKHKLGASQNCSATTKGNLKLTNVV-------LPETKDWRKDGIVSPVKAQGKCGSCWT 165
Query: 145 FSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK 204
FSTTG +E + + K +SLSEQ LVDC + GCNGGL A+ YI
Sbjct: 166 FSTTGALEAAYAQAFGKGISLSEQQLVDCAGAFNNF--------GCNGGLPSQAFEYIKF 217
Query: 205 NGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVS-TGPLAIAAD 263
NGG+ TE +YPYT + G C F+ ANIG K+ + I Y V+ P+++A +
Sbjct: 218 NGGLDTEEAYPYTGKNGI-CKFSQANIGVKVISSVNITLGAEYELKYAVALVRPVSVAFE 276
Query: 264 AVE-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 319
V+ ++ Y GV+ + P ++H +L VGY +N PYW++KNSWGADWGE
Sbjct: 277 VVKGFKQYKSGVYASTECGDTPMDVNHAVLAVGYGVEN-----GTPYWLIKNSWGADWGE 331
Query: 320 QGYIYLRRGKNTCGVSNFVSTSII 343
GY + GKN CGV+ S I+
Sbjct: 332 DGYFKMEMGKNMCGVATCASYPIV 355
>sp|O60911|CATM_HUMAN CATHEPSIN L2 PRECURSOR (CATHEPSIN V)
Length = 334
Score = 210 bits (528), Expect = 5e-54
Identities = 127/349 (36%), Positives = 191/349 (54%), Gaps = 35/349 (10%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQS---QFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEE 61
L VLA F + ++S +P +Q+ ++ +++ + Y E R +++ N+ IE
Sbjct: 3 LSLVLAAFCLGIAS-AVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIEL 61
Query: 62 LNLIAINHKADTKFGVNKFADLSSDEFKNY---YLNNK---EAIFTDDLPVADYLDDEFI 115
N K +N F D++++EF+ + N K +F + L +LD
Sbjct: 62 HNGEYSQGKHGFTMAMNAFPDMTNEEFRQMMGCFRNQKFRKGKVFREPL----FLD---- 113
Query: 116 NSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 175
+P + DWR +G VTPVKNQ QCGSCW+FS TG +EGQ F KLVSLSEQNLVDC
Sbjct: 114 --LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSR 171
Query: 176 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKI 235
+G ++GCNGG A+ Y+ +NGG+ +E SYPY A C + N A
Sbjct: 172 P----QG----NQGCNGGFMARAFQYVKENGGLDSEESYPYVA-VDEICKYRPENSVAND 222
Query: 236 SNFTMI-PKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIV 291
+ FT++ P E + + + GP+++A DA +QFY G+ F+ C+ +LDHG+L+V
Sbjct: 223 TGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVV 282
Query: 292 GYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVS 339
GY + N YW+VKNSWG +WG GY+ + + KN CG++ S
Sbjct: 283 GYGFEGA-NSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAAS 330
>sp|P54639|CYS4_DICDI CYSTEINE PROTEINASE 4 PRECURSOR
Length = 442
Score = 209 bits (527), Expect = 6e-54
Identities = 116/300 (38%), Positives = 167/300 (55%), Gaps = 24/300 (8%)
Query: 4 ILLFVLAVFTVFVSSRGIPPEEQ--SQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEE 61
+L F+ + + S++ E Q + F + + YS EE+ R++IFKSN+ + +
Sbjct: 3 VLSFLCLLLVSYASAKQQFSELQYRNAFTNWMQAHQRTYSSEEFNARYQIFKSNMDYVHQ 62
Query: 62 LNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTA 121
N + +T G+N FAD+++ E++ YL F + + F PT
Sbjct: 63 WN----SKGGETVLGLNVFADITNQEYRTTYLGTP---FDGSALIGTEEEKIFSTPAPTV 115
Query: 122 FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFIS---QNKLVSLSEQNLVDCDHECM 178
DWR +GAVTP+KNQGQCG CWSFSTTG+ EG HFI+ + LVSLSEQNL+DC
Sbjct: 116 -DWRAQGAVTPIKNQGQCGGCWSFSTTGSTEGAHFIASGTKKDLVSLSEQNLIDCS---- 170
Query: 179 EYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNF 238
+ + GC GGL + YII N GI TESSYPYTAE G +C F ++NIGA+I ++
Sbjct: 171 ----KSYGNNGCEGGLMTLGFEYIINNKGIDTESSYPYTAEDGKECKFKTSNIGAQIVSY 226
Query: 239 TMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGILIVGYSA 295
+ + P+++A DA +Q Y G++ P C P LDHG+L+VGY +
Sbjct: 227 QNVTSGSEASLQSASNNAPVSVAIDASNESFQLYESGIYYEPACTPTQLDHGVLVVGYGS 286
Score = 48.8 bits (114), Expect = 2e-05
Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 306 YWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 339
YWIVKNSWG WG GYI++ + + N CG++ S
Sbjct: 401 YWIVKNSWGTSWGMDGYIFMSKDRNNNCGIATMAS 435
>sp|Q10991|CATL_SHEEP CATHEPSIN L
Length = 217
Score = 209 bits (527), Expect = 6e-54
Identities = 104/226 (46%), Positives = 140/226 (61%), Gaps = 17/226 (7%)
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
+P + DW +G VTPVKNQGQCGSCW+FS TG +EGQ F KLVSLSEQNLVD
Sbjct: 1 VPKSVDWTKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVD----- 55
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN 237
++GCNGGL NA+ YI +NGG+ +E SYPY A T T CN+ AK +
Sbjct: 56 ---SSRPQGNQGCNGGLMDNAFQYIKENGGLDSEESYPYEA-TDTSCNYKPEYSAAKDTG 111
Query: 238 FTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYS 294
F IP+ E + + + GP+++A DA +QFY G+ +D C+ LDHG+L+VGY
Sbjct: 112 FVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYG 171
Query: 295 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVS 339
+ T N +WIVKNSWG +WG +GY+ + + +N CG++ S
Sbjct: 172 FEGT----NNKFWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAAS 213
>sp|P25803|CYSP_PHAVU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYSTEINE PROTEINASE EP-C1)
Length = 362
Score = 208 bits (523), Expect = 2e-53
Identities = 124/306 (40%), Positives = 176/306 (56%), Gaps = 29/306 (9%)
Query: 47 ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNK---EAIFTDD 103
+RF +FK+NL + N + +K +NKFAD+++ EF++ Y +K +F
Sbjct: 58 KRFNVFKANLMHVHNTNKMDKPYKLK----LNKFADMTNHEFRSTYAGSKVNHPRMFRGT 113
Query: 104 LPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLV 163
E + S+P + DWR +GAVT VK+QGQCGSCW+FST VEG + I NKLV
Sbjct: 114 PHENGAFMYEKVVSVPPSVDWRKKGAVTDVKDQGQCGSCWAFSTVVAVEGINQIKTNKLV 173
Query: 164 SLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ 223
+LSEQ LVDCD E ++GCNGGL +A+ +I + GGI TES+YPY A+ GT
Sbjct: 174 ALSEQELVDCDKE---------ENQGCNGGLMESAFEFIKQKGGITTESNYPYKAQEGT- 223
Query: 224 CNFNSAN-IGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCN 280
C+ + N + I +P N+ V+ P+++A DA ++QFY GVF C+
Sbjct: 224 CDASKVNDLAVSIDGHENVPANDEDALLKAVANQPVSVAIDAGGSDFQFYSEGVFTGDCS 283
Query: 281 PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVSN 336
L+HG+ IVGY T+ N YWIV+NSWG +WGE GYI ++R + CG++
Sbjct: 284 -TDLNHGVAIVGYG--TTVDGTN--YWIVRNSWGPEWGEHGYIRMQRNISKKEGLCGIAM 338
Query: 337 FVSTSI 342
S I
Sbjct: 339 LPSYPI 344
>sp|P00785|ACTN_ACTCH ACTINIDAIN PRECURSOR (ACTINIDIN)
Length = 380
Score = 206 bits (520), Expect = 4e-53
Identities = 123/327 (37%), Positives = 176/327 (53%), Gaps = 35/327 (10%)
Query: 24 EEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADT----KFGVN 78
E ++ + + K+ K Y S E+ RFEIFK L I+E H ADT K G+N
Sbjct: 37 EVKAMYESWLIKYGKSYNSLGEWERRFEIFKETLRFIDE-------HNADTNRSYKVGLN 89
Query: 79 KFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQ 138
+FADL+ +EF++ YL ++ V++ + F +P+ DWR+ GAV +K+QG+
Sbjct: 90 QFADLTDEEFRSTYLGFTSG--SNKTKVSNRYEPRFGQVLPSYVDWRSAGAVVDIKSQGE 147
Query: 139 CGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNA 198
CG CW+FS VEG + I L+SLSEQ L+DC G GCNGG +
Sbjct: 148 CGGCWAFSAIATVEGINKIVTGVLISLSEQELIDC--------GRTQNTRGCNGGYITDG 199
Query: 199 YNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG-AKISNFTMIPKNETVMAGYIVSTGP 257
+ +II NGGI TE +YPYTA+ G +CN + N I + +P N V+ P
Sbjct: 200 FQFIINNGGINTEENYPYTAQDG-ECNLDLQNEKYVTIDTYENVPYNNEWALQTAVTYQP 258
Query: 258 LAIAADAV--EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGA 315
+++A DA ++ Y G+F PC ++DH + IVGY + I YWIVKNSW
Sbjct: 259 VSVALDAAGDAFKHYSSGIFTGPCG-TAIDHAVTIVGYGTEGGI-----DYWIVKNSWDT 312
Query: 316 DWGEQGYIYLRR---GKNTCGVSNFVS 339
WGE+GY+ + R G TCG++ S
Sbjct: 313 TWGEEGYMRILRNVGGAGTCGIATMPS 339
>sp|P43156|CYSP_HEMSP THIOL PROTEASE SEN102 PRECURSOR
Length = 360
Score = 203 bits (510), Expect = 6e-52
Identities = 125/304 (41%), Positives = 164/304 (53%), Gaps = 30/304 (9%)
Query: 43 EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTD 102
+E RF +FK N+ I E N A K +NKF D+++ EF++ Y +K
Sbjct: 54 DEKNRRFNVFKENVKFIHEFNQ---KKDAPYKLALNKFGDMTNQEFRSKYAGSKIQHHRS 110
Query: 103 DLPVADYLDD---EFINSIPTA-FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFIS 158
+ E + S+P A DWR +GAVT VK+QGQCGSCW+FST +VEG + I
Sbjct: 111 QRGIQKNTGSFMYENVGSLPAASIDWRAKGAVTGVKDQGQCGSCWAFSTIASVEGINQIK 170
Query: 159 QNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTA 218
+LVSLSEQ LVDCD + +EGCNGGL A+ +I KN GI TE SYPY
Sbjct: 171 TGELVSLSEQELVDCD---------TSYNEGCNGGLMDYAFEFIQKN-GITTEDSYPYAE 220
Query: 219 ETGTQCNFNSANIG-AKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVF 275
+ GT C N N I +P N V+ P++++ +A +QFY GVF
Sbjct: 221 QDGT-CASNLLNSPVVSIDGHQDVPANNENALMQAVANQPISVSIEASGYGFQFYSEGVF 279
Query: 276 DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNT 331
C LDHG+ IVGY A R YWIVKNSWG +WGE GYI ++RG +
Sbjct: 280 TGRCG-TELDHGVAIVGYGAT----RDGTKYWIVKNSWGEEWGESGYIRMQRGISDKRGK 334
Query: 332 CGVS 335
CG++
Sbjct: 335 CGIA 338
>sp|P25777|ORYB_ORYSA ORYZAIN BETA CHAIN PRECURSOR
Length = 471
Score = 203 bits (510), Expect = 6e-52
Identities = 115/303 (37%), Positives = 165/303 (53%), Gaps = 25/303 (8%)
Query: 44 EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDD 103
E+ RF +F NL ++ N A + + G+N+FADL+++EF+ +L K A
Sbjct: 69 EHERRFLVFWDNLKFVDAHNARA-DEGGGFRLGMNRFADLTNEEFRATFLGAKVA--ERS 125
Query: 104 LPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLV 163
+ + + +P + DWR +GAV PVKNQGQCGSCW+FS VE + + +++
Sbjct: 126 RAAGERYRHDGVEELPESVDWREKGAVAPVKNQGQCGSCWAFSAVSTVESINQLVTGEMI 185
Query: 164 SLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ 223
+LSEQ LV+C + GCNGGL +A+++IIKNGGI TE YPY A G +
Sbjct: 186 TLSEQELVEC--------STNGQNSGCNGGLMADAFDFIIKNGGIDTEDDYPYKAVDG-K 236
Query: 224 CNFNSANIG-AKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCN 280
C+ N N I F +P+N+ V+ P+++A +A E+Q Y GVF C
Sbjct: 237 CDINRENAKVVSIDGFEDVPQNDEKSLQKAVAHQPVSVAIEAGGREFQLYHSGVFSGRCG 296
Query: 281 PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT----CGVSN 336
SLDHG++ VGY N YWIV+NSWG WGE GY+ + R N CG++
Sbjct: 297 -TSLDHGVVAVGYGTDN-----GKDYWIVRNSWGPKWGESGYVRMERNINVTTGKCGIAM 350
Query: 337 FVS 339
S
Sbjct: 351 MAS 353
>sp|Q10717|CYS2_MAIZE CYSTEINE PROTEINASE 2 PRECURSOR
Length = 360
Score = 201 bits (505), Expect = 2e-51
Identities = 119/327 (36%), Positives = 175/327 (53%), Gaps = 36/327 (11%)
Query: 28 QFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
+F F ++ K Y S E +RF IF +L + N ++++ G+N+FAD+S +
Sbjct: 58 RFARFAVRYGKSYESAAEVHKRFRIFSESLQLVRSTNRKGLSYR----LGINRFADMSWE 113
Query: 87 EFKNYYLN---NKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCW 143
EF+ L N A T ++ ++P DWR G V+PVKNQG CGSCW
Sbjct: 114 EFRATRLGAAQNCSATLT-----GNHRMRAAAVALPETKDWREDGIVSPVKNQGHCGSCW 168
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+FSTTG +E + + K +SLSEQ LVDC + GCNGGL A+ YI
Sbjct: 169 TFSTTGALEAAYTQATGKPISLSEQQLVDCGFAFNNF--------GCNGGLPSQAFEYIK 220
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKI---SNFTMIPKNETVMAGYIVSTGPLAI 260
NGG+ TE SYPY G C F + N+G K+ N T+ ++E A +V P+++
Sbjct: 221 YNGGLDTEESYPYQGVNGI-CKFKNENVGVKVLDSVNITLGAEDELKDAVGLVR--PVSV 277
Query: 261 AADAVE-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGAD 316
A + + ++ Y GV+ P ++H +L VGY ++ +PYW++KNSWGAD
Sbjct: 278 AFEVITGFRLYKSGVYTSDHCGTTPMDVNHAVLAVGYGVED-----GVPYWLIKNSWGAD 332
Query: 317 WGEQGYIYLRRGKNTCGVSNFVSTSII 343
WG++GY + GKN CGV+ S I+
Sbjct: 333 WGDEGYFKMEMGKNMCGVATCASYPIV 359
>sp|P00786|CATH_RAT CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPSIN BA)
Length = 333
Score = 200 bits (504), Expect = 3e-51
Identities = 121/324 (37%), Positives = 172/324 (52%), Gaps = 28/324 (8%)
Query: 25 EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
E+ F + + K YS EY R ++F +N KI+ N NH K G+N+F+D+S
Sbjct: 29 EKFHFTSWMKQHQKTYSSREYSHRLQVFANNWRKIQAHN--QRNHTF--KMGLNQFSDMS 84
Query: 85 SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRG-AVTPVKNQGQCGSCW 143
E K+ YL ++ ++YL P++ DWR +G V+PVKNQG CGSCW
Sbjct: 85 FAEIKHKYLWSEPQ--NCSATKSNYLRGT--GPYPSSMDWRKKGNVVSPVKNQGACGSCW 140
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+FSTTG +E I+ K+++L+EQ LVDC + + GC GGL A+ YI+
Sbjct: 141 TFSTTGALESAVAIASGKMMTLAEQQLVDC--------AQNFNNHGCQGGLPSQAFEYIL 192
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAA 262
N GI E SYPY + G QC FN A + N I N E M + P++ A
Sbjct: 193 YNKGIMGEDSYPYIGKNG-QCKFNPEKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAF 251
Query: 263 DAVE-WQFYIGGVFDI-PCN--PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 318
+ E + Y GV+ C+ P+ ++H +L VGY +N + YWIVKNSWG++WG
Sbjct: 252 EVTEDFMMYKSGVYSSNSCHKTPDKVNHAVLAVGYGEQNGLL-----YWIVKNSWGSNWG 306
Query: 319 EQGYIYLRRGKNTCGVSNFVSTSI 342
GY + RGKN CG++ S I
Sbjct: 307 NNGYFLIERGKNMCGLAACASYPI 330
>sp|O10364|CATV_NPVOP VIRAL CATHEPSIN (V-CATH)
Length = 324
Score = 199 bits (500), Expect = 9e-51
Identities = 118/316 (37%), Positives = 170/316 (53%), Gaps = 26/316 (8%)
Query: 29 FLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
F +F KFNK YS E E L RF+IF+ NL +I N + + ++ +NKF+DLS +E
Sbjct: 28 FEDFLHKFNKNYSSESEKLHRFKIFQHNLEEIINKN----QNDSTAQYEINKFSDLSKEE 83
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
+ Y T + LD P FDWR VT VKNQG CG+CW+F+T
Sbjct: 84 AISKYTGLSLPHQTQNFCEVVILDRPPDRG-PLEFDWRQFNKVTSVKNQGVCGACWAFAT 142
Query: 148 TGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGG 207
G++E Q I N+L++LSEQ +DCD + GC+GGL A+ ++ GG
Sbjct: 143 LGSLESQFAIKYNRLINLSEQQFIDCDR----------VNAGCDGGLLHTAFESAMEMGG 192
Query: 208 IQTESSYPYTAETGTQCNFNSAN--IGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV 265
+Q ES YPY G QC N +G + S I E + + + GP+ +A DA
Sbjct: 193 VQMESDYPYETANG-QCRINPNRFVVGVR-SCRRYIVMFEEKLKDLLRAVGPIPVAIDAS 250
Query: 266 EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
+ Y G+ C + L+H +L+VGY+ +N N+PYWI+KN+WG DWGE GY +
Sbjct: 251 DIVNYRRGIMR-QCANHGLNHAVLLVGYAVEN-----NIPYWILKNTWGTDWGEDGYFRV 304
Query: 326 RRGKNTCGVSNFVSTS 341
++ N CG+ N + +S
Sbjct: 305 QQNINACGIRNELVSS 320
>sp|P43297|RD21_ARATH CYSTEINE PROTEINASE RD21A PRECURSOR
Length = 462
Score = 198 bits (498), Expect = 2e-50
Identities = 119/313 (38%), Positives = 165/313 (52%), Gaps = 35/313 (11%)
Query: 35 KFNKKYSHEEYLE---RFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNY 91
K K S +E RFEIFK NL ++E N ++++ G+ +FADL++DE+++
Sbjct: 56 KHGKAQSQNSLVEKDRRFEIFKDNLRFVDEHNEKNLSYR----LGLTRFADLTNDEYRSK 111
Query: 92 YLN---NKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTT 148
YL K+ L + DE +P + DWR +GAV VK+QG CGSCW+FST
Sbjct: 112 YLGAKMEKKGERRTSLRYEARVGDE----LPESIDWRKKGAVAEVKDQGGCGSCWAFSTI 167
Query: 149 GNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGI 208
G VEG + I L++LSEQ LVDCD + +EGCNGGL A+ +IIKNGGI
Sbjct: 168 GAVEGINQIVTGDLITLSEQELVDCD---------TSYNEGCNGGLMDYAFEFIIKNGGI 218
Query: 209 QTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VE 266
T+ YPY GT I ++ +P V+ P++IA +A
Sbjct: 219 DTDKDYPYKGVDGTCDQIRKNAKVVTIDSYEDVPTYSEESLKKAVAHQPISIAIEAGGRA 278
Query: 267 WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLR 326
+Q Y G+FD C LDHG++ VGY +N YWIV+NSWG WGE GY+ +
Sbjct: 279 FQLYDSGIFDGSCG-TQLDHGVVAVGYGTEN-----GKDYWIVRNSWGKSWGESGYLRMA 332
Query: 327 R----GKNTCGVS 335
R CG++
Sbjct: 333 RNIASSSGKCGIA 345
>sp|P15242|TES1_RAT TESTIN 1/2 PRECURSOR (CMB-22/CMB-23)
Length = 333
Score = 198 bits (497), Expect = 2e-50
Identities = 115/348 (33%), Positives = 184/348 (52%), Gaps = 22/348 (6%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQS--QFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
+I + LA+ + V S P+ ++ E++ K K Y+ E + +++ N IE
Sbjct: 1 MIAVLFLAILCLEVDSTAPTPDPSLDVEWNEWRTKHGKTYNMNEERLKRAVWEKNFKMIE 60
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLN-NKEAIFTDDLPVADYLDDEFINSIP 119
N + + D +N F DL++ EF ++ I + + D +F+ +P
Sbjct: 61 LHNWEYLEGRHDFTMAMNAFGDLTNIEFVKMMTGFQRQKIKKTHI----FQDHQFLY-VP 115
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
DWR G VTPVKNQG C S W+FS TG++EGQ F +L+ LSEQNL+DC +
Sbjct: 116 KRVDWRQLGYVTPVKNQGHCASSWAFSATGSLEGQMFRKTERLIPLSEQNLLDCMGSNVT 175
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
+ GC+GG A+ Y+ NGG+ TE SYPY + G +C +++ N A + +F
Sbjct: 176 H--------GCSGGFMQYAFQYVKDNGGLATEESYPYRGQ-GRECRYHAENSAANVRDFV 226
Query: 240 MIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGYSAK 296
IP +E + + GP+++A DA +QFY G++ P C L+H +L+VGY +
Sbjct: 227 QIPGSEEALMKAVAKVGPISVAVDASHGSFQFYGSGIYYEPQCKRVHLNHAVLVVGYGFE 286
Query: 297 NTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 343
N +W+VKNSWG +WG +GY+ L + N CG++ + + I+
Sbjct: 287 GEESDGN-SFWLVKNSWGEEWGMKGYMKLAKDWSNHCGIATYSTYPIV 333
>sp|P25776|ORYA_ORYSA ORYZAIN ALPHA CHAIN PRECURSOR
Length = 458
Score = 198 bits (497), Expect = 2e-50
Identities = 122/348 (35%), Positives = 182/348 (52%), Gaps = 37/348 (10%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQSQ--FLEFQDKFNKKYSHE-EYLERFEIFKSNLGKI 59
++LL LA + + S G EE+++ + E++ + K Y+ E R+ F+ NL I
Sbjct: 12 LLLLLSLAAADMSIVSYGERSEEEARRLYAEWKAEHGKSYNAVGEEERRYAAFRDNLRYI 71
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLN-----NKEAIFTDDLPVADYLDDEF 114
+E N A + G+N+FADL+++E+++ YL +E +D AD
Sbjct: 72 DEHNAAADAGVHSFRLGLNRFADLTNEEYRDTYLGLRNKPRRERKVSDRYLAADN----- 126
Query: 115 INSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCD 174
++P + DWRT+GAV +K+QG CGSCW+FS VE + I L+SLSEQ LVDCD
Sbjct: 127 -EALPESVDWRTKGAVAEIKDQGGCGSCWAFSAIAAVEDINQIVTGDLISLSEQELVDCD 185
Query: 175 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG-A 233
+ +EGCNGGL A+++II NGGI TE YPY + +C+ N N
Sbjct: 186 ---------TSYNEGCNGGLMDYAFDFIINNGGIDTEDDYPYKGK-DERCDVNRKNAKVV 235
Query: 234 KISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDHGILIV 291
I ++ + N V P+++A +A +Q Y G+F C +LDHG+ V
Sbjct: 236 TIDSYEDVTPNSETSLQKAVRNQPVSVAIEAGGRAFQLYSSGIFTGKCG-TALDHGVAAV 294
Query: 292 GYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR----GKNTCGVS 335
GY +N YWIV+NSWG WGE GY+ + R CG++
Sbjct: 295 GYGTEN-----GKDYWIVRNSWGKSWGESGYVRMERNIKASSGKCGIA 337
>sp|P14080|PAP2_CARPA CHYMOPAPAIN PRECURSOR (PAPAYA PROTEINASE II) (PPII)
Length = 352
Score = 194 bits (488), Expect = 2e-49
Identities = 125/315 (39%), Positives = 167/315 (52%), Gaps = 43/315 (13%)
Query: 35 KFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKF--GVNKFADLSSDEFKNY 91
K NK Y S +E + RFEIF+ NL I+E N K + + G+N FADLS+DEFK
Sbjct: 54 KHNKIYESIDEKIYRFEIFRDNLMYIDETN------KKNNSYWLGLNGFADLSNDEFKKK 107
Query: 92 YLNNKEAIFTDDLPVADYLDDE-----FINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFS 146
Y+ +D ++ D+E + + P + DWR +GAVTPVKNQG CGSCW+FS
Sbjct: 108 YVG----FVAEDFTGLEHFDNEDFTYKHVTNYPQSIDWRAKGAVTPVKNQGACGSCWAFS 163
Query: 147 TTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNG 206
T VEG + I L+ LSEQ LVDCD GC GG Q + Y + N
Sbjct: 164 TIATVEGINKIVTGNLLELSEQELVDCDKH----------SYGCKGGYQTTSLQY-VANN 212
Query: 207 GIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAADA- 264
G+ T YPY A+ + KI+ + +P N ET G + + PL++ +A
Sbjct: 213 GVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSNCETSFLGALANQ-PLSVLVEAG 271
Query: 265 -VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 323
+Q Y GVFD PC LDH + VGY + KN Y I+KNSWG +WGE+GY+
Sbjct: 272 GKPFQLYKSGVFDGPCG-TKLDHAVTAVGYGTSD---GKN--YIIIKNSWGPNWGEKGYM 325
Query: 324 YLRR----GKNTCGV 334
L+R + TCGV
Sbjct: 326 RLKRQSGNSQGTCGV 340
>sp|P43235|CATK_HUMAN CATHEPSIN K PRECURSOR (CATHEPSIN O) (CATHEPSIN X) (CATHEPSIN O2)
Length = 329
Score = 194 bits (488), Expect = 2e-49
Identities = 121/339 (35%), Positives = 180/339 (52%), Gaps = 25/339 (7%)
Query: 9 LAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
L V + V S + PEE + + ++ K+Y+++ + + R I++ NL I NL
Sbjct: 4 LKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLE 63
Query: 66 AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWR 125
A + +N D++S+E K + Y+ E+ P + D+R
Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIP-EWEGRAPDSVDYR 122
Query: 126 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEA 185
+G VTPVKNQGQCGSCW+FS+ G +EGQ KL++LS QNLVDC E
Sbjct: 123 KKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--------- 173
Query: 186 CDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPK-N 244
++GC GG NA+ Y+ KN GI +E +YPY + C +N AK + IP+ N
Sbjct: 174 -NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQE-ESCMYNPTGKAAKCRGYREIPEGN 231
Query: 245 ETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFR 301
E + + GP+++A DA +QFY GV +D CN ++L+H +L VGY +
Sbjct: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYG-----IQ 286
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 339
K +WI+KNSWG +WG +GYI + R K N CG++N S
Sbjct: 287 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLAS 325
>sp|P25778|ORYC_ORYSA ORYZAIN GAMMA CHAIN PRECURSOR
Length = 362
Score = 194 bits (487), Expect = 3e-49
Identities = 114/327 (34%), Positives = 171/327 (51%), Gaps = 37/327 (11%)
Query: 28 QFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
+F F + K+Y E RF IF +L + N + ++ G+N+FAD+S +
Sbjct: 61 RFARFAVRHGKRYGDAAEVQRRFRIFSESLELVRSTNRRGLPYR----LGINRFADMSWE 116
Query: 87 EFKNYYLN---NKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCW 143
EF+ L N A + + D ++P DWR G V+PVK+QG CGSCW
Sbjct: 117 EFQASRLGAAQNCSATLAGNHRMRD------APALPETKDWREDGIVSPVKDQGHCGSCW 170
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
FSTTG++E ++ + VSLSEQ L DC + GC+GGL A+ YI
Sbjct: 171 PFSTTGSLEARYTQATGPPVSLSEQQLADCATRYNNF--------GCSGGLPSQAFEYIK 222
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKI---SNFTMIPKNETVMAGYIVSTGPLAI 260
NGG+ TE +YPYT G C++ N G K+ N T++ ++E A +V P+++
Sbjct: 223 YNGGLDTEEAYPYTGVNGI-CHYKPENAGVKVLDSVNITLVAEDELKNAVGLVR--PVSV 279
Query: 261 AADAVE-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGAD 316
A + ++ Y GV+ +P ++H +L VGY +N +PYW++KNSWGAD
Sbjct: 280 AFQVINGFRMYKSGVYTSDHCGTSPMDVNHAVLAVGYGVEN-----GVPYWLIKNSWGAD 334
Query: 317 WGEQGYIYLRRGKNTCGVSNFVSTSII 343
WG+ GY + GKN CG++ S I+
Sbjct: 335 WGDNGYFTMEMGKNMCGIATCASYPIV 361
>sp|P25251|CYS4_BRANA CYSTEINE PROTEINASE COT44 PRECURSOR
Length = 328
Score = 194 bits (487), Expect = 3e-49
Identities = 115/300 (38%), Positives = 160/300 (53%), Gaps = 29/300 (9%)
Query: 47 ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNK----EAIFTD 102
ERF IFK NL I+ N N A K G+ FA+L++DE+++ YL + I
Sbjct: 27 ERFNIFKDNLRFIDLHN--ENNKNATYKLGLTIFANLTNDEYRSLYLGARTEPVRRITKA 84
Query: 103 DLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKL 162
Y ++ +P DWR +GAV +K+QG CGSCW+FST VEG + I +L
Sbjct: 85 KNVNMKYSAAVNVDEVPVTVDWRQKGAVNAIKDQGTCGSCWAFSTAAAVEGINKIVTGEL 144
Query: 163 VSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGT 222
VSLSEQ LVDCD ++ ++GCNGGL A+ +I+KNGG+ TE YPY G
Sbjct: 145 VSLSEQELVDCD---------KSYNQGCNGGLMDYAFQFIMKNGGLNTEKDYPYHGTNG- 194
Query: 223 QCNFNSANIG-AKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPC 279
+CN N I + +P + VS P+++A DA +Q Y G+F C
Sbjct: 195 KCNSLLKNSRVVTIDGYEDVPSKDETALKRAVSYQPVSVAIDAGGRAFQHYQSGIFTGKC 254
Query: 280 NPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVS 335
N +DH ++ VGY ++N + YWIV+NSWG WGE GYI + R CG++
Sbjct: 255 GTN-MDHAVVAVGYGSEN-----GVDYWIVRNSWGTRWGEDGYIRMERNVASKSGKCGIA 308
>sp|P09668|CATH_HUMAN CATHEPSIN H PRECURSOR
Length = 335
Score = 192 bits (482), Expect = 1e-48
Identities = 122/326 (37%), Positives = 168/326 (51%), Gaps = 32/326 (9%)
Query: 25 EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
E+ F + K K YS EEY R + F SN KI N N K +N+F+D+S
Sbjct: 31 EKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHN----NGNHTFKMALNQFSDMS 86
Query: 85 SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGA-VTPVKNQGQCGSCW 143
E K+ YL ++ ++YL P + DWR +G V+PVKNQG CGSCW
Sbjct: 87 FAEIKHKYLWSEPQ--NCSATKSNYLRGT--GPYPPSVDWRKKGNFVSPVKNQGACGSCW 142
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+FSTTG +E I+ K++SL+EQ LVDC + Y GC GGL A+ YI+
Sbjct: 143 TFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNY--------GCQGGLPSQAFEYIL 194
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSAN-IG--AKISNFTMIPKNETVMAGYIVSTGPLAI 260
N GI E +YPY + G C F IG ++N T+ +E M + P++
Sbjct: 195 YNKGIMGEDTYPYQGKDG-YCKFQPGKAIGFVKDVANITIY--DEEAMVEAVALYNPVSF 251
Query: 261 AADAV-EWQFYIGGVF-DIPCN--PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGAD 316
A + ++ Y G++ C+ P+ ++H +L VGY KN I PYWIVKNSWG
Sbjct: 252 AFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGI-----PYWIVKNSWGPQ 306
Query: 317 WGEQGYIYLRRGKNTCGVSNFVSTSI 342
WG GY + RGKN CG++ S I
Sbjct: 307 WGMNGYFLIERGKNMCGLAACASYPI 332
>sp|O46427|CATH_PIG CATHEPSIN H PRECURSOR
Length = 335
Score = 191 bits (481), Expect = 2e-48
Identities = 122/332 (36%), Positives = 171/332 (50%), Gaps = 28/332 (8%)
Query: 17 SSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFG 76
S+ + E+ F + + KKYS EEY R ++F SN KI N A NH K G
Sbjct: 23 SNLAVSSFEKLHFKSWMVQHQKKYSLEEYHHRLQVFVSNWRKINAHN--AGNHTF--KLG 78
Query: 77 VNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGA-VTPVKN 135
+N+F+D+S DE ++ YL ++ +YL P + DWR +G V+PVKN
Sbjct: 79 LNQFSDMSFDEIRHKYLWSEPQ--NCSATKGNYLRGT--GPYPPSMDWRKKGNFVSPVKN 134
Query: 136 QGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQ 195
QG CGSCW+FSTTG +E I+ K++SL+EQ LVDC + + GC GGL
Sbjct: 135 QGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDC--------AQNFNNHGCQGGLP 186
Query: 196 PNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVS 254
A+ YI N GI E +YPY + C F A + + I N E M +
Sbjct: 187 SQAFEYIRYNKGIMGEDTYPYKGQ-DDHCKFQPDKAIAFVKDVANITMNDEEAMVEAVAL 245
Query: 255 TGPLAIAADAV-EWQFYIGGVF-DIPCN--PNSLDHGILIVGYSAKNTIFRKNMPYWIVK 310
P++ A + ++ Y G++ C+ P+ ++H +L VGY +N I PYWIVK
Sbjct: 246 YNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGI-----PYWIVK 300
Query: 311 NSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
NSWG WG GY + RGKN CG++ S I
Sbjct: 301 NSWGPQWGMNGYFLIERGKNMCGLAACASYPI 332
>sp|P05167|ALEU_HORVU THIOL PROTEASE ALEURAIN PRECURSOR
Length = 362
Score = 191 bits (481), Expect = 2e-48
Identities = 111/322 (34%), Positives = 167/322 (51%), Gaps = 27/322 (8%)
Query: 28 QFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
+F F ++ K Y S E RF IF +L ++ N + ++ G+N+F+D+S +
Sbjct: 60 RFARFAVRYGKSYESAAEVRRRFRIFSESLEEVRSTNRKGLPYR----LGINRFSDMSWE 115
Query: 87 EFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFS 146
EF+ L A T +A ++P DWR G V+PVKNQ CGSCW+FS
Sbjct: 116 EFQATRLG---AAQTCSATLAGNHLMRDAAALPETKDWREDGIVSPVKNQAHCGSCWTFS 172
Query: 147 TTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNG 206
TTG +E + + K +SLSEQ LVDC + GCNGGL A+ YI NG
Sbjct: 173 TTGALEAAYTQATGKNISLSEQQLVDCAGGFNNF--------GCNGGLPSQAFEYIKYNG 224
Query: 207 GIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAADAV 265
GI TE SYPY G C++ + N ++ + I N E + + P+++A +
Sbjct: 225 GIDTEESYPYKGVNGV-CHYKAENAAVQVLDSVNITLNAEDELKNAVGLVRPVSVAFQVI 283
Query: 266 E-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQG 321
+ ++ Y GV+ P+ ++H +L VGY +N +PYW++KNSWGADWG+ G
Sbjct: 284 DGFRQYKSGVYTSDHCGTTPDDVNHAVLAVGYGVEN-----GVPYWLIKNSWGADWGDNG 338
Query: 322 YIYLRRGKNTCGVSNFVSTSII 343
Y + GKN C ++ S ++
Sbjct: 339 YFKMEMGKNMCAIATCASYPVV 360
>sp|P43236|CATK_RABIT CATHEPSIN K PRECURSOR (OC-2 PROTEIN)
Length = 329
Score = 191 bits (480), Expect = 2e-48
Identities = 119/339 (35%), Positives = 179/339 (52%), Gaps = 25/339 (7%)
Query: 9 LAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
L V + V S + PEE +Q+ ++ ++K+Y+ + + + R I++ NL I NL
Sbjct: 4 LKVLLLPVVSFALHPEEILDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLE 63
Query: 66 AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWR 125
A + +N D++S+E K Y+ D + P + D+R
Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSRSHSNDTLYIPD-WEGRTPDSIDYR 122
Query: 126 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEA 185
+G VTPVKNQGQCGSCW+FS+ G +EGQ KL++LS QNLVDC E
Sbjct: 123 KKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--------- 173
Query: 186 CDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPK-N 244
+ GC GG NA+ Y+ +N GI +E +YPY + C +N AK + IP+ N
Sbjct: 174 -NYGCGGGYMTNAFQYVQRNRGIDSEDAYPYVGQ-DESCMYNPTGKAAKCRGYREIPEGN 231
Query: 245 ETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFR 301
E + + GP+++A DA +QFY GV +D C+ ++++H +L VGY +
Sbjct: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDENCSSDNVNHAVLAVGYG-----IQ 286
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 339
K +WI+KNSWG WG +GYI + R K N CG++N S
Sbjct: 287 KGNKHWIIKNSWGESWGNKGYILMARNKNNACGIANLAS 325
>sp|P10056|PAP3_CARPA CARICAIN PRECURSOR (PAPAYA PROTEINASE OMEGA) (PAPAYA PROTEINASE
III) (PPIII) (PAPAYA PEPTIDASE A)
Length = 348
Score = 190 bits (479), Expect = 3e-48
Identities = 122/319 (38%), Positives = 166/319 (51%), Gaps = 46/319 (14%)
Query: 37 NKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKF--GVNKFADLSSDEFKNYYL 93
NK Y + +E L RFEIFK NL I+E N K + + G+N+FADLS+DEF Y+
Sbjct: 56 NKFYENVDEKLYRFEIFKDNLNYIDETN------KKNNSYWLGLNEFADLSNDEFNEKYV 109
Query: 94 NNKEAIFTDDLPVADYLDDEFIN----SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTG 149
+ D + D+EFIN ++P DWR +GAVTPV++QG CGSCW+FS
Sbjct: 110 GS-----LIDATIEQSYDEEFINEDTVNLPENVDWRKKGAVTPVRHQGSCGSCWAFSAVA 164
Query: 150 NVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ 209
VEG + I KLV LSEQ LVDC+ GC GG P A Y+ KN GI
Sbjct: 165 TVEGINKIRTGKLVELSEQELVDCERR----------SHGCKGGYPPYALEYVAKN-GIH 213
Query: 210 TESSYPYTAETGTQCNFNSANIGAKISNFTMI----PKNETVMAGYIVSTGPLAIAADAV 265
S YPY A+ GT + +G I + + P NE + I P+++ ++
Sbjct: 214 LRSKYPYKAKQGT---CRAKQVGGPIVKTSGVGRVQPNNEGNLLNAIAKQ-PVSVVVESK 269
Query: 266 --EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 323
+Q Y GG+F+ PC +DH + VGY Y ++KNSWG WGE+GYI
Sbjct: 270 GRPFQLYKGGIFEGPCG-TKVDHAVTAVGYGKSG-----GKGYILIKNSWGTAWGEKGYI 323
Query: 324 YLRRGK-NTCGVSNFVSTS 341
++R N+ GV +S
Sbjct: 324 RIKRAPGNSPGVCGLYKSS 342
>sp|P49935|CATH_MOUSE CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPSIN BA)
Length = 333
Score = 189 bits (476), Expect = 6e-48
Identities = 117/324 (36%), Positives = 167/324 (51%), Gaps = 28/324 (8%)
Query: 25 EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
E+ F + + K YS EY R ++F +N KI+ N NH K +N+F+D+S
Sbjct: 29 EKFHFKSWMKQHQKTYSSVEYNHRLQMFANNWRKIQAHN--QRNHTF--KMALNQFSDMS 84
Query: 85 SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRG-AVTPVKNQGQCGSCW 143
E K+ +L ++ ++YL P++ DWR +G V+PVKNQG C SCW
Sbjct: 85 FAEIKHKFLWSEPQ--NCSATKSNYLRGT--GPYPSSMDWRKKGNVVSPVKNQGACASCW 140
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+FSTTG +E I+ K++SL+EQ LVDC + + GC GGL A+ YI+
Sbjct: 141 TFSTTGALESAVAIASGKMLSLAEQQLVDC--------AQAFNNHGCKGGLPSQAFEYIL 192
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAA 262
N GI E SYPY + + C FN A + N I N E M + P++ A
Sbjct: 193 YNKGIMEEDSYPYIGK-DSSCRFNPQKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAF 251
Query: 263 DAVE-WQFYIGGVFDIPC---NPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 318
+ E + Y GV+ P+ ++H +L VGY +N + YWIVKNSWG+ WG
Sbjct: 252 EVTEDFLMYKSGVYSSKSCHKTPDKVNHAVLAVGYGEQNGLL-----YWIVKNSWGSQWG 306
Query: 319 EQGYIYLRRGKNTCGVSNFVSTSI 342
E GY + RGKN CG++ S I
Sbjct: 307 ENGYFLIERGKNMCGLAACASYPI 330
>sp|P55097|CATK_MOUSE CATHEPSIN K PRECURSOR
Length = 329
Score = 188 bits (473), Expect = 1e-47
Identities = 117/344 (34%), Positives = 181/344 (52%), Gaps = 35/344 (10%)
Query: 9 LAVFTVFVSSRGIPPEEQ--SQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
L V + + S + PEE +Q+ ++ K+Y+ + + + R I++ NL +I NL
Sbjct: 4 LKVLLLPMVSFALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLE 63
Query: 66 AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDD-----EFINSIPT 120
A + +N D++S+E + P Y +D E+ +P
Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIP------PSRSYSNDTLYTPEWEGRVPD 117
Query: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
+ D+R +G VTPVKNQGQCGSCW+FS+ G +EGQ KL++LS QNLVDC E
Sbjct: 118 SIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE---- 173
Query: 181 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM 240
+ GC GG A+ Y+ +NGGI +E ++PY + C +N+ AK +
Sbjct: 174 ------NYGCGGGYMTTAFQYVQQNGGIDSEDAFPYVGQ-DESCMYNATAKAAKCRGYRE 226
Query: 241 IP-KNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAK 296
IP NE + + GP++++ DA +QFY GV +D C+ ++++H +L+VGY
Sbjct: 227 IPVGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGT- 285
Query: 297 NTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 339
+K +WI+KNSWG WG +GY L R K N CG++N S
Sbjct: 286 ----QKGSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMAS 325
>sp|P56203|CATW_MOUSE CATHEPSIN W PRECURSOR (LYMPHOPAIN)
Length = 371
Score = 185 bits (466), Expect = 9e-47
Identities = 110/338 (32%), Positives = 164/338 (47%), Gaps = 32/338 (9%)
Query: 22 PPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKF 80
P E + F FQ +FN+ Y + EY R IF NL + + L + +FG F
Sbjct: 33 PLELKEVFKLFQIRFNRSYWNPAEYTRRLSIFAHNLAQAQRLQQEDLG---TAEFGETPF 89
Query: 81 ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWR-TRGAVTPVKNQGQC 139
+DL+ +EF Y + T ++ + + S+P DWR + ++ VKNQG C
Sbjct: 90 SDLTEEEFGQLYGQERSPERTPNM-TKKVESNTWGESVPRTCDWRKAKNIISSVKNQGSC 148
Query: 140 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 199
CW+ + N++ I + V +S Q L+DC E C GCNGG +AY
Sbjct: 149 KCCWAMAAADNIQALWRIKHQQFVDVSVQELLDC----------ERCGNGCNGGFVWDAY 198
Query: 200 NYIIKNGGIQTESSYPYTAETGT-QCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPL 258
++ N G+ +E YP+ + +C A I +FTM+ NE +A Y+ GP+
Sbjct: 199 LTVLNNSGLASEKDYPFQGDRKPHRCLAKKYKKVAWIQDFTMLSNNEQAIAHYLAVHGPI 258
Query: 259 AIAADAVEWQFYIGGVFDIP---CNPNSLDHGILIVGYSAKN------TIF------RKN 303
+ + Q Y GV C+P +DH +L+VG+ K T+ R +
Sbjct: 259 TVTINMKLLQHYQKGVIKATPSSCDPRQVDHSVLLVGFGKKKEGMQTGTVLSHSRKRRHS 318
Query: 304 MPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
PYWI+KNSWGA WGE+GY L RG NTCGV+ + T+
Sbjct: 319 SPYWILKNSWGAHWGEKGYFRLYRGNNTCGVTKYPFTA 356
>sp|P25250|CYS2_HORVU CYSTEINE PROTEINASE EP-B 2 PRECURSOR
Length = 373
Score = 184 bits (463), Expect = 2e-46
Identities = 123/345 (35%), Positives = 172/345 (49%), Gaps = 40/345 (11%)
Query: 8 VLAVFTVFVSSRGIPPEEQSQFLE---------FQDKFNKKYSHEEYLERFEIFKSNLGK 58
VLAV V + S IP E++ E +Q + H E RF FKSN
Sbjct: 17 VLAVAAVELCS-AIPMEDKDLESEEALWDLYERWQSAHRVRRHHAEKHRRFGTFKSNAHF 75
Query: 59 IEELNLIAINHKADTKFGV--NKFADLSSDEFKNYYLNNKEAIFTDDLP-VADYLDDEF- 114
I + N + D + + N+F D+ EF+ ++ + P V ++
Sbjct: 76 IH-----SHNKRGDHPYRLHLNRFGDMDQAEFRATFVGDLRRDTPSKPPSVPGFMYAALN 130
Query: 115 INSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCD 174
++ +P + DWR +GAVT VK+QG+CGSCW+FST +VEG + I LVSLSEQ L+DCD
Sbjct: 131 VSDLPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCD 190
Query: 175 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNF----NSAN 230
A ++GC GGL NA+ YI NGG+ TE++YPY A GT CN ++
Sbjct: 191 ---------TADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGT-CNVARAAQNSP 240
Query: 231 IGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDHGI 288
+ I +P N V+ P+++A +A + FY GVF C LDHG+
Sbjct: 241 VVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGECG-TELDHGV 299
Query: 289 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCG 333
+VGY + YW VKNSWG WGEQGYI + + G
Sbjct: 300 AVVGYG----VAEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASG 340
>sp|P25249|CYS1_HORVU CYSTEINE PROTEINASE EP-B 1 PRECURSOR
Length = 371
Score = 184 bits (462), Expect = 3e-46
Identities = 124/349 (35%), Positives = 171/349 (48%), Gaps = 48/349 (13%)
Query: 8 VLAVFTVFVSSRGIPPEEQSQFLE---------FQDKFNKKYSHEEYLERFEIFKSNLGK 58
VLAV V + S IP E++ E +Q + H E RF FKSN
Sbjct: 17 VLAVAAVELCS-AIPMEDKDLESEEALWDLYERWQSAHRVRRHHAEKHRRFGTFKSNAHF 75
Query: 59 IEELNLIAINHKADTKFGV--NKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEF-- 114
I + N + D + + N+F D+ EF+ ++ + D P F
Sbjct: 76 IH-----SHNKRGDHPYRLHLNRFGDMDQAEFRATFVGDLRR----DTPAKPPSVPGFMY 126
Query: 115 ----INSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNL 170
++ +P + DWR +GAVT VK+QG+CGSCW+FST +VEG + I LVSLSEQ L
Sbjct: 127 AALNVSDLPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQEL 186
Query: 171 VDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNF---- 226
+DCD A ++GC GGL NA+ YI NGG+ TE++YPY A GT CN
Sbjct: 187 IDCD---------TADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGT-CNVARAA 236
Query: 227 NSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSL 284
++ + I +P N V+ P+++A +A + FY GVF C L
Sbjct: 237 QNSPVVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGDCG-TEL 295
Query: 285 DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCG 333
DHG+ +VGY + YW VKNSWG WGEQGYI + + G
Sbjct: 296 DHGVAVVGYG----VAEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASG 340
>sp|P05994|PAP4_CARPA PAPAYA PROTEINASE IV PRECURSOR (PPIV) (PAPAYA PEPTIDASE B) (GLYCYL
ENDOPEPTIDASE)
Length = 348
Score = 183 bits (461), Expect = 3e-46
Identities = 112/309 (36%), Positives = 164/309 (52%), Gaps = 33/309 (10%)
Query: 35 KFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYL 93
K NK Y + +E L RFEIFK NL I+E N + + G+N+F+DLS+DEFK Y+
Sbjct: 54 KHNKNYKNVDEKLYRFEIFKDNLKYIDERNKMINGYW----LGLNEFSDLSNDEFKEKYV 109
Query: 94 NNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 153
+ +T+ ++++++ ++ +P + DWR +GAVTPVK+QG C SCW+FST VEG
Sbjct: 110 GSLPEDYTNQPYDEEFVNEDIVD-LPESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEG 168
Query: 154 QHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESS 213
+ I LV LSEQ LVDCD + GCN G Q + Y+ +N GI +
Sbjct: 169 INKIKTGNLVELSEQELVDCDKQ----------SYGCNRGYQSTSLQYVAQN-GIHLRAK 217
Query: 214 YPYTAETGTQCNFNSANIGAKI--SNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQF 269
YPY A+ T C N G K+ + + N ++ P+++ ++ ++Q
Sbjct: 218 YPYIAKQQT-CRANQVG-GPKVKTNGVGRVQSNNEGSLLNAIAHQPVSVVVESAGRDFQN 275
Query: 270 YIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK 329
Y GG+F+ C +DH + VGY Y ++KNSWG WGE GYI +RR
Sbjct: 276 YKGGIFEGSCG-TKVDHAVTAVGYGKSG-----GKGYILIKNSWGPGWGENGYIRIRRAS 329
Query: 330 ----NTCGV 334
CGV
Sbjct: 330 GNSPGVCGV 338
>sp|P22895|P34_SOYBN P34 PROBABLE THIOL PROTEASE PRECURSOR
Length = 379
Score = 183 bits (461), Expect = 3e-46
Identities = 108/318 (33%), Positives = 171/318 (52%), Gaps = 38/318 (11%)
Query: 40 YSHEEYLERFEIFKSNLGKIEELNLIAINHKA--DTKFGVNKFADLSSDEFKNYYLNNKE 97
++HEE +R EIFK+N I ++N N K+ + G+NKFAD++ EF YL +
Sbjct: 56 HNHEEEAKRLEIFKNNSNYIRDMNA---NRKSPHSHRLGLNKFADITPQEFSKKYLQAPK 112
Query: 98 AIFTDDLPVADYL---DDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQ 154
+ + + +A+ + + P ++DWR +G +T VK QG CG W+FS TG +E
Sbjct: 113 DV-SQQIKMANKKMKKEQYSCDHPPASWDWRKKGVITQVKYQGGCGRGWAFSATGAIEAA 171
Query: 155 HFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSY 214
H I+ LVSLSEQ LVDC E EG G Q ++ +++++GGI T+ Y
Sbjct: 172 HAIATGDLVSLSEQELVDCVEE----------SEGSYNGWQYQSFEWVLEHGGIATDDDY 221
Query: 215 PYTAETGTQCNFNSANIGAKISNF-TMIPKNETVMAG------YIVSTGPLAIAADAVEW 267
PY A+ G +C N I + T+I +E+ + + P++++ DA ++
Sbjct: 222 PYRAKEG-RCKANKIQDKVTIDGYETLIMSDESTESETEQAFLSAILEQPISVSIDAKDF 280
Query: 268 QFYIGGVFDIP--CNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
Y GG++D +P ++H +L+VGY + + + YWI KNSWG DWGE GYI++
Sbjct: 281 HLYTGGIYDGENCTSPYGINHFVLLVGYGSAD-----GVDYWIAKNSWGFDWGEDGYIWI 335
Query: 326 RRGK----NTCGVSNFVS 339
+R CG++ F S
Sbjct: 336 QRNTGNLLGVCGMNYFAS 353
>sp|P43234|CATO_HUMAN CATHEPSIN O PRECURSOR
Length = 321
Score = 182 bits (458), Expect = 8e-46
Identities = 98/299 (32%), Positives = 155/299 (51%), Gaps = 28/299 (9%)
Query: 52 FKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLD 111
F+ +L + LN + + + +G+N+F+ L +EFK YL +K + F Y
Sbjct: 44 FRESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPR------YSA 97
Query: 112 DEFIN----SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSE 167
+ ++ S+P FDWR + VT V+NQ CG CW+FS G VE + I L LS
Sbjct: 98 EVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSV 157
Query: 168 QNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK-NGGIQTESSYPYTAETGTQCNF 226
Q ++DC + + GCNGG NA N++ K + +S YP+ A+ G F
Sbjct: 158 QQVIDCSYN----------NYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYF 207
Query: 227 NSANIGAKISNFTM--IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSL 284
+ ++ G I ++ E MA +++ GPL + DAV WQ Y+GG+ C+
Sbjct: 208 SGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGIIQHHCSSGEA 267
Query: 285 DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
+H +LI G+ + PYWIV+NSWG+ WG GY +++ G N CG+++ VS+ +
Sbjct: 268 NHAVLITGFDKTG-----STPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV 321
>sp|P56202|CATW_HUMAN CATHEPSIN W PRECURSOR (LYMPHOPAIN)
Length = 376
Score = 182 bits (457), Expect = 1e-45
Identities = 109/341 (31%), Positives = 170/341 (48%), Gaps = 35/341 (10%)
Query: 22 PPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKF 80
P E + F FQ +FN+ Y S EE+ R +IF NL + + L + +FGV F
Sbjct: 35 PLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLG---TAEFGVTPF 91
Query: 81 ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWR-TRGAVTPVKNQGQC 139
+DL+ +EF Y + A + + +E S+P + DWR GA++P+K+Q C
Sbjct: 92 SDLTEEEFGQLYGYRRAAGGVPSMG-REIRSEEPEESVPFSCDWRKVAGAISPIKDQKNC 150
Query: 140 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 199
CW+ + GN+E IS V +S L+DC C +GC+GG +A+
Sbjct: 151 NCCWAMAAAGNIETLWRISFWDFVDVSVHELLDCGR----------CGDGCHGGFVWDAF 200
Query: 200 NYIIKNGGIQTESSYPYTAETGT-QCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPL 258
++ N G+ +E YP+ + +C+ A I +F M+ NE +A Y+ + GP+
Sbjct: 201 ITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPI 260
Query: 259 AIAADAVEWQFYIGGVFDIP---CNPNSLDHGILIVGYSA--------KNTIFRKNMP-- 305
+ + Q Y GV C+P +DH +L+VG+ + T+ ++ P
Sbjct: 261 TVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQP 320
Query: 306 -----YWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
YWI+KNSWGA WGE+GY L RG NTCG++ F T+
Sbjct: 321 PHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTA 361
>sp|P25774|CATS_HUMAN CATHEPSIN S PRECURSOR
Length = 331
Score = 177 bits (444), Expect = 3e-44
Identities = 116/347 (33%), Positives = 176/347 (50%), Gaps = 35/347 (10%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYS--HEEYLERFEIFKSNLGKIEEL 62
L+ VL V + V+ P + ++ + K+Y +EE + R I++ NL +
Sbjct: 4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRL-IWEKNLKFVMLH 62
Query: 63 NLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINS----- 117
NL G+N D++S+E + T L V
Sbjct: 63 NLEHSMGMHSYDLGMNHLGDMTSEEVMS---------LTSSLRVPSQWQRNITYKSNPNR 113
Query: 118 -IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
+P + DWR +G VT VK QG CG+CW+FS G +E Q + KLV+LS QNLVDC
Sbjct: 114 ILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDC--- 170
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
E+ ++GCNGG A+ YII N GI +++SYPY A +C ++S A S
Sbjct: 171 ----STEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKA-MDQKCQYDSKYRAATCS 225
Query: 237 NFTMIP-KNETVMAGYIVSTGPLAIAADAVEWQFYI--GGVFDIPCNPNSLDHGILIVGY 293
+T +P E V+ + + GP+++ DA F++ GV+ P +++HG+L+VGY
Sbjct: 226 KYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGY 285
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 339
N YW+VKNSWG ++GE+GYI + R K N CG+++F S
Sbjct: 286 GDLN-----GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPS 327
>sp|P00784|PAPA_CARPA PAPAIN PRECURSOR (PAPAYA PROTEINASE I) (PPI)
Length = 345
Score = 176 bits (442), Expect = 6e-44
Identities = 116/315 (36%), Positives = 161/315 (50%), Gaps = 37/315 (11%)
Query: 35 KFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKF--GVNKFADLSSDEFKNY 91
K NK Y + +E + RFEIFK NL I+E N K + + G+N FAD+S+DEFK
Sbjct: 54 KHNKIYKNIDEKIYRFEIFKDNLKYIDETN------KKNNSYWLGLNVFADMSNDEFKEK 107
Query: 92 YLNNKEAIFTD-DLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGN 150
Y + +T +L + L+D +N IP DWR +GAVTPVKNQG CGSCW+FS
Sbjct: 108 YTGSIAGNYTTTELSYEEVLNDGDVN-IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVT 166
Query: 151 VEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQT 210
+EG I L SEQ L+DCD GCNGG +A ++ GI
Sbjct: 167 IEGIIKIRTGNLNEYSEQELLDCDRR----------SYGCNGGYPWSALQ-LVAQYGIHY 215
Query: 211 ESSYPYTAETGTQCNFNSANIGAKISNFTMI-PKNETVMAGYIVSTGPLAIAADAV--EW 267
++YPY + AK + P NE + Y ++ P+++ +A ++
Sbjct: 216 RNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALL-YSIANQPVSVVLEAAGKDF 274
Query: 268 QFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR 327
Q Y GG+F PC N +DH + VGY Y ++KNSWG WGE GYI ++R
Sbjct: 275 QLYRGGIFVGPCG-NKVDHAVAAVGYGPN---------YILIKNSWGTGWGENGYIRIKR 324
Query: 328 GK-NTCGVSNFVSTS 341
G N+ GV ++S
Sbjct: 325 GTGNSYGVCGLYTSS 339
>sp||CATL_CHICK_1 [Segment 1 of 2] CATHEPSIN L
Length = 176
Score = 175 bits (439), Expect = 1e-43
Identities = 88/179 (49%), Positives = 117/179 (65%), Gaps = 12/179 (6%)
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECM 178
P + DWR +G VTPVK+QGQCGSCW+FSTTG +EGQHF ++ KLVSLSEQNLVDC
Sbjct: 2 PRSVDWREKGYVTPVKDQGQCGSCWAFSTTGALEGQHFRTKGKLVSLSEQNLVDCSRP-- 59
Query: 179 EYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNF 238
EG ++GCNGGL A+ Y+ NGGI +E SYPYTA+ C + + A + F
Sbjct: 60 --EG----NQGCNGGLMDQAFQYVQDNGGIDSEESYPYTAKDDEDCRYKAEYNAANDTGF 113
Query: 239 TMIPK-NETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGILIVGY 293
IP+ +E + + S GP+++A DA +QFY G++ P C+ LDHG+L+VGY
Sbjct: 114 VDIPQGHERALMKAVASVGPVSVAIDAGHSSFQFYQSGIYYEPDCSSEDLDHGVLVVGY 172
>sp|P25326|CATS_BOVIN CATHEPSIN S
Length = 217
Score = 173 bits (434), Expect = 5e-43
Identities = 91/226 (40%), Positives = 131/226 (57%), Gaps = 17/226 (7%)
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
+P + DWR +G VT VK QG CGSCW+FS G +E Q + KLVSLS QNLVDC
Sbjct: 1 LPDSMDWREKGCVTEVKYQGACGSCWAFSAVGALEAQVKLKTGKLVSLSAQNLVDC---- 56
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN 237
+ ++GCNGG A+ YII N GI +E+SYPY A G +C ++ N A S
Sbjct: 57 ---STAKYGNKGCNGGFMTEAFQYIIDNNGIDSEASYPYKAMDG-KCQYDVKNRAATCSR 112
Query: 238 FTMIP-KNETVMAGYIVSTGPLAIAADAVEWQFYI--GGVFDIPCNPNSLDHGILIVGYS 294
+ +P +E + + + GP+++ DA F++ GV+ P +++HG+L+VGY
Sbjct: 113 YIELPFGSEEALKEAVANKGPVSVGIDASHSSFFLYKTGVYYDPSCTQNVNHGVLVVGYG 172
Query: 295 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 339
+ YW+VKNSWG +G+QGYI + R N CG++N+ S
Sbjct: 173 NLD-----GKDYWLVKNSWGLHFGDQGYIRMARNSGNHCGIANYPS 213
>sp|P80884|ANAN_ANACO ANANAIN
Length = 216
Score = 167 bits (419), Expect = 3e-41
Identities = 93/223 (41%), Positives = 124/223 (54%), Gaps = 22/223 (9%)
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
+P + DWR GAVT VKNQG+CGSCW+F++ VE + I + LVSLSEQ ++DC
Sbjct: 1 VPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDC---- 56
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN 237
A GC GG AY++II N G+ + + YPY A GT C N A I+
Sbjct: 57 -------AVSYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGT-CKTNGVPNSAYITR 108
Query: 238 FTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAK 296
+T + +N Y VS P+A A DA +Q Y GVF PC L+H I+I+GY
Sbjct: 109 YTYVQRNNERNMMYAVSNQPIAAALDASGNFQHYKRGVFTGPCG-TRLNHAIVIIGYGQD 167
Query: 297 NTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT----CGVS 335
+ +WIV+NSWGA WGE GYI L R ++ CG++
Sbjct: 168 SA----GKKFWIVRNSWGAGWGEGGYIRLARDVSSSFGICGIA 206
>sp|Q02765|CATS_RAT CATHEPSIN S PRECURSOR
Length = 330
Score = 167 bits (418), Expect = 4e-41
Identities = 90/228 (39%), Positives = 132/228 (57%), Gaps = 18/228 (7%)
Query: 117 SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
++P + DWR +G VT VK QG CGSCW+FS G +EGQ + KLVSLS QNLVDC E
Sbjct: 112 TLPDSVDWREKGCVTNVKYQGSCGSCWAFSAEGALEGQLKLKTGKLVSLSAQNLVDCSTE 171
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
E+ ++GC GG A+ YII + I +E+SYPY A +C ++ N A S
Sbjct: 172 ------EKYGNKGCGGGFMTEAFQYII-DTSIDSEASYPYKA-MDEKCLYDPKNRAATCS 223
Query: 237 NFTMIP-KNETVMAGYIVSTGPLAIAADAV---EWQFYIGGVFDIPCNPNSLDHGILIVG 292
+ +P +E + + + GP+++ D + Y GV+D P +++HG+L+VG
Sbjct: 224 RYIELPFGDEEALKEAVATKGPVSVGIDDASHSSFFLYQSGVYDDPSCTENMNHGVLVVG 283
Query: 293 YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL-RRGKNTCGVSNFVS 339
Y + YW+VKNSWG +G+QGYI + R KN CG++++ S
Sbjct: 284 YGTLD-----GKDYWLVKNSWGLHFGDQGYIRMARNNKNHCGIASYCS 326
>sp|P20721|CYSL_LYCES LOW-TEMPERATURE-INDUCED CYSTEINE PROTEINASE PRECURSOR
Length = 346
Score = 164 bits (410), Expect = 3e-40
Identities = 86/226 (38%), Positives = 127/226 (56%), Gaps = 21/226 (9%)
Query: 116 NSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 175
+S+P + DWR +G + VK+QG CGSCW+FS +E + I L+SLSEQ LVDCD
Sbjct: 16 DSLPESIDWREKGVLVGVKDQGSCGSCWAFSAVAAMESINAIVTGNLISLSEQELVDCD- 74
Query: 176 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKI 235
+ +EGC+GGL A+ ++IKNGGI TE YPY G + KI
Sbjct: 75 --------RSYNEGCDGGLMDYAFEFVIKNGGIDTEEDYPYKERNGVCDQYRKNAKVVKI 126
Query: 236 SNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGY 293
++ +P N V+ P++IA +A ++Q Y G+F C ++DHG++I GY
Sbjct: 127 DSYEDVPVNNEKALQKAVAHQPVSIALEAGGRDFQHYKSGIFTGKCG-TAVDHGVVIAGY 185
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT----CGVS 335
+N M YWIV+NSWGA+ E GY+ ++R ++ CG++
Sbjct: 186 GTEN-----GMDYWIVRNSWGANCRENGYLRVQRNVSSSSGLCGLA 226
>sp|P36184|ACP1_ENTHI CYSTEINE PROTEINASE ACP1 PRECURSOR
Length = 308
Score = 162 bits (407), Expect = 7e-40
Identities = 105/312 (33%), Positives = 150/312 (47%), Gaps = 40/312 (12%)
Query: 29 FLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
F ++ NK +++ EYL RF +F N +E A+ +N FAD++ +E
Sbjct: 18 FKQWAATHNKVFANRAEYLYRFAVFLDNKKFVE----------ANANTELNVFADMTHEE 67
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
F +L T ++P + + P + DWR+ + P K+QGQCGSCW+F T
Sbjct: 68 FIQTHLG-----MTYEVPETTSNVKAAVKAAPESVDWRS--IMNPAKDQGQCGSCWTFCT 120
Query: 148 TGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGG 207
T +EG+ KL S SEQ LVDCD A D GC GG N+ +I +N G
Sbjct: 121 TAVLEGRVNKDLGKLYSFSEQQLVDCD----------ASDNGCEGGHPSNSLKFIQENNG 170
Query: 208 IQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--V 265
+ ES YPY A GT C N+ + + +ET + I GP+A+ DA
Sbjct: 171 LGLESDYPYKAVAGT-CK-KVKNVATVTGSRRVTDGSETGLQTIIAENGPVAVGMDASRP 228
Query: 266 EWQFYIGGVF--DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 323
+Q Y G D C ++H + VGY + + N YWI++NSWG WG+ GY
Sbjct: 229 SFQLYKKGTIYSDTKCRSRMMNHCVTAVGYGSNS-----NGKYWIIRNSWGTSWGDAGYF 283
Query: 324 YLRR-GKNTCGV 334
L R N CG+
Sbjct: 284 LLARDSNNMCGI 295
>sp|O17473|CATL_BRUPA CATHEPSIN L-LIKE PRECURSOR
Length = 395
Score = 159 bits (398), Expect = 8e-39
Identities = 101/323 (31%), Positives = 155/323 (47%), Gaps = 21/323 (6%)
Query: 26 QSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
++++ ++ K Y +E R IF+SN E +N +N ADL+
Sbjct: 88 ETEWKDYVTALGKHYDQKENNFRMAIFESNELMTERINKKYEQGLVSYTTALNDLADLTD 147
Query: 86 DEF--KNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCW 143
+EF +N + +++ + +P DWRT+GAVTPV+NQG+CGSC+
Sbjct: 148 EEFMVRNGLRLPNQTDLRGKRQTSEFYRYDKSERLPDQVDWRTKGAVTPVRNQGECGSCY 207
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+F+T +E H +L+ LS QN+VDC + GC+GG P A+ Y
Sbjct: 208 AFATAAALEAYHKQMTGRLLDLSPQNIVDCT--------RNLGNNGCSGGYMPTAFQYAS 259
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMI-PKNETVMAGYIVSTGP--LAI 260
+ GI ES YPY T +C + + + F I P +E + + GP + I
Sbjct: 260 RY-GIAMESRYPYVG-TEQRCRWQQSIAVVTDNGFNEIQPGDELALKHAVAKRGPVVVGI 317
Query: 261 AADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQ 320
+ ++FY GV+ N DH +L VGY + YWIVKNSWG DWG+
Sbjct: 318 SGSKRSFRFYKDGVYS-EGNCGRPDHAVLAVGYGTHPSY----GDYWIVKNSWGTDWGKD 372
Query: 321 GYIYLRRGK-NTCGVSNFVSTSI 342
GY+Y+ R + N C +++ S I
Sbjct: 373 GYVYMARNRGNMCHIASAASFPI 395
>sp|Q01957|CPP1_ENTHI CYSTEINE PROTEINASE 1 PRECURSOR
Length = 315
Score = 156 bits (391), Expect = 5e-38
Identities = 108/309 (34%), Positives = 166/309 (52%), Gaps = 39/309 (12%)
Query: 37 NKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADT-KFGVN-KFADLSSDEFKNYYLN 94
NK ++ E L R IF N ++A N++ +T K V+ FA ++++E+ N L
Sbjct: 24 NKHFTAVESLRRRAIFNMNA------RIVAENNRKETFKLSVDGPFAAMTNEEY-NSLLK 76
Query: 95 NKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQ 154
K + ++ YL+ + P A DWR +G VTP+++QG CGSC++F + +EG+
Sbjct: 77 LKRS--GEEKGEVRYLNIQ----APKAVDWRKKGKVTPIRDQGNCGSCYTFGSIAALEGR 130
Query: 155 HFISQ---NKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTE 211
I + ++ + LSE+++V C E +G + GCNGGL N YNYI++N GI E
Sbjct: 131 LLIEKGGDSETLDLSEEHMVQCTRE----DG----NNGCNGGLGSNVYNYIMEN-GIAKE 181
Query: 212 SSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQF 269
S YPYT T C + AKI ++ + +N V +S G + ++ DA V++Q
Sbjct: 182 SDYPYTGSDST-CR-SDVKAFAKIKSYNRVARNNEVELKAAISQGLVDVSIDASSVQFQL 239
Query: 270 YIGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLR 326
Y G + D C N +L+H + VGY + WIV+NSWG WGE+GYI +
Sbjct: 240 YKSGAYTDTQCKNNYFALNHEVCAVGYGVVD-----GKECWIVRNSWGTGWGEKGYINMV 294
Query: 327 RGKNTCGVS 335
NTCGV+
Sbjct: 295 IEGNTCGVA 303
>sp|Q06964|CPP3_ENTHI CYSTEINE PROTEINASE 3 PRECURSOR (CYSTEINE PROTEINASE ACP3)
Length = 308
Score = 153 bits (384), Expect = 4e-37
Identities = 103/308 (33%), Positives = 159/308 (51%), Gaps = 37/308 (12%)
Query: 37 NKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN-KFADLSSDEFKNYYLNN 95
NK ++ E L R IF N + E N K K V+ FA ++++E++ L +
Sbjct: 17 NKHFTAVEALRRRAIFNMNARFVAEFN-----KKGSFKLSVDGPFAAMTNEEYRTL-LKS 70
Query: 96 KEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQH 155
K + ++ YL+ + P + DWR +G VTP+++Q QCGSC++F + +EG+
Sbjct: 71 KRTV--EENGKVTYLNIQ----APESVDWRAQGKVTPIRDQAQCGSCYTFGSLAALEGRL 124
Query: 156 FISQN---KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTES 212
I + + LSE++LV C + + GCNGGL N Y+YII+N G+ ES
Sbjct: 125 LIEKGGNANTLDLSEEHLVQCT--------RDNGNNGCNGGLGSNVYDYIIQN-GVAKES 175
Query: 213 SYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFY 270
YPYT T + C N AKI+ + +P+N +S G + ++ DA ++Q Y
Sbjct: 176 DYPYTG-TDSTCKTN-VKAFAKITGYNKVPRNNEAELKAALSQGLVDVSIDASSAKFQLY 233
Query: 271 IGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR 327
G + D C N +L+H + VGY + WIV+NSWG WG++GYI +
Sbjct: 234 KSGAYSDTKCKNNFFALNHEVCAVGYGVVD-----GKECWIVRNSWGTGWGDKGYINMVI 288
Query: 328 GKNTCGVS 335
NTCGV+
Sbjct: 289 EGNTCGVA 296
>sp|Q01958|CPP2_ENTHI CYSTEINE PROTEINASE 2 PRECURSOR
Length = 315
Score = 153 bits (383), Expect = 5e-37
Identities = 102/316 (32%), Positives = 161/316 (50%), Gaps = 37/316 (11%)
Query: 29 FLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN-KFADLSSDE 87
F + K NK ++ E L R IF N ++ N I K V+ FA ++++E
Sbjct: 16 FNTWASKNNKHFTAIEKLRRRAIFNMNAKFVDSFNKIG-----SFKLSVDGPFAAMTNEE 70
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
++ + + T++ YL+ + P + DWR G VTP+++Q QCGSC++F +
Sbjct: 71 YRTLLKSKRT---TEENGQVKYLNIQ----APESVDWRKEGKVTPIRDQAQCGSCYTFGS 123
Query: 148 TGNVEGQHFISQN---KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK 204
+EG+ I + + LSE+++V C + + GCNGGL N Y+YII+
Sbjct: 124 LAALEGRLLIEKGGDANTLDLSEEHMVQCT--------RDNGNNGCNGGLGSNVYDYIIE 175
Query: 205 NGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA 264
+ G+ ES YPYT T C N + AKI+ +T +P+N +S G + ++ DA
Sbjct: 176 H-GVAKESDYPYTGSDST-CKTNVKSF-AKITGYTKVPRNNEAELKAALSQGLVDVSIDA 232
Query: 265 --VEWQFYIGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 319
++Q Y G + D C N +L+H + VGY + WIV+NSWG WG+
Sbjct: 233 SSAKFQLYKSGAYTDTKCKNNYFALNHEVCAVGYGVVD-----GKECWIVRNSWGTGWGD 287
Query: 320 QGYIYLRRGKNTCGVS 335
+GYI + NTCGV+
Sbjct: 288 KGYINMVIEGNTCGVA 303
>sp|P46102|CYSP_PLAVN CYSTEINE PROTEINASE PRECURSOR
Length = 506
Score = 153 bits (382), Expect = 6e-37
Identities = 115/358 (32%), Positives = 176/358 (49%), Gaps = 62/358 (17%)
Query: 27 SQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
S+F ++ + NKKY + +E L+RFE FK K ++ N + + VN+++D S
Sbjct: 160 SKFFKYMKENNKKYENMDEQLQRFENFKIRYMKTQKHNEMVGKNGLTYVQKVNQYSDFSK 219
Query: 86 DEFKNYYLNNKEAIFTDDL------PVADYLDDEFINSI-------PTAFDWRTRGAVTP 132
+EF NY+ K DL P+ +L + + S+ P + D+R++ P
Sbjct: 220 EEFDNYF--KKLLSVPMDLKSKYIVPLKKHLANTNLISVDNKSKDFPDSRDYRSKFNFLP 277
Query: 133 VKNQGQCGSCWSFSTTGNVEGQHFISQNKL-VSLSEQNLVDCDHECMEYEGEEACDEGCN 191
K+QG CGSCW+F+ GN E + +++++ +S SEQ +VDC E + GC+
Sbjct: 278 PKDQGNCGSCWAFAAIGNFEYLYVHTRHEMPISFSEQQMVDCSTE----------NYGCD 327
Query: 192 GGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGY 251
GG A+ Y+I NG + YPY C ++ ++ + NE +MA
Sbjct: 328 GGNPFYAFLYMINNG-VCLGDEYPYKGHEDFFCLNYRCSLLGRVHFIGDVKPNELIMALN 386
Query: 252 IVSTGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSA--------------- 295
V GP+ IA A E + Y GGVFD CNP L+H +L+VGY
Sbjct: 387 YV--GPVTIAVGASEDFVLYSGGVFDGECNPE-LNHSVLLVGYGQVKKSLAFEDSHSNVD 443
Query: 296 KNTI--FRKNMP---------YWIVKNSWGADWGEQGYIYLRRGK----NTCGVSNFV 338
N I +++N+ YWIV+NSWG +WGE GYI ++R K CGV + V
Sbjct: 444 SNLIKKYKENIKGDDDDDIIYYWIVRNSWGPNWGEGGYIRIKRNKAGDDGFCGVGSDV 501
>sp|P36185|ACP2_ENTHI CYSTEINE PROTEINASE ACP2 PRECURSOR
Length = 310
Score = 150 bits (374), Expect = 5e-36
Identities = 102/322 (31%), Positives = 160/322 (49%), Gaps = 32/322 (9%)
Query: 20 GIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN- 78
GI F + K NK ++ E L R IF N ++ N I K V+
Sbjct: 3 GIRIASAIDFNTWASKNNKHFTAIEKLRRRAIFNMNAKFVDSFNKIG-----SFKLSVDG 57
Query: 79 KFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQ 138
FA ++++E++ + + T++ YL+ + P + DWR G VTP+++Q Q
Sbjct: 58 PFAAMTNEEYRTLLKSKRT---TEENGQVKYLNIQ----APESVDWRKEGKVTPLRDQAQ 110
Query: 139 CGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNA 198
CGSC++F + +EG+ I + + N +D E M+ + + GCNGGL N
Sbjct: 111 CGSCYTFGSLAALEGRLLIEKG-----GDANTLDLSEEHMQCTRDNG-NNGCNGGLGSNV 164
Query: 199 YNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPL 258
Y+YII++ G+ ES YPYT T C N + KI+ +T +P+N +S G L
Sbjct: 165 YDYIIEH-GVAKESDYPYTGSDST-CKTNVKSF-RKITGYTKVPRNNEAELKAALSQGLL 221
Query: 259 AIAAD--AVEWQFYIGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMPYWIVKNSW 313
++ D + ++Q Y G + D C N +L+H + VGY + WIV+NSW
Sbjct: 222 DVSIDVSSAKFQLYKSGAYTDTKCKNNYFALNHEVCAVGYGVVD-----GKECWIVRNSW 276
Query: 314 GADWGEQGYIYLRRGKNTCGVS 335
G WG++GYI + NTCGV+
Sbjct: 277 GTSWGDKGYINMVIEGNTCGVA 298
>sp|P25781|CYSP_THEAN CYSTEINE PROTEINASE PRECURSOR
Length = 441
Score = 146 bits (366), Expect = 5e-35
Identities = 107/339 (31%), Positives = 164/339 (47%), Gaps = 54/339 (15%)
Query: 28 QFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGV--NKFADLS 84
+F F +K+ K + S ++ ++RF F+ N ++ HK + + NKF+DLS
Sbjct: 119 EFDAFVEKYKKVHRSFDQRVQRFLTFRKNYHIVK-------THKPTEPYSLDLNKFSDLS 171
Query: 85 SDEFKNYY--------------------LNNKEAIFTDDLPVADYLDDEFINSIPTA--F 122
+EFK Y +++K I+ L A +++ S+ T
Sbjct: 172 DEEFKALYPVITPPKTYTSLSKHLEFKKMSHKNPIYISKLKKAKGIEEIKDLSLITGENL 231
Query: 123 DWRTRGAVTPVKNQGQ-CGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYE 181
+W AV+P K+QG CGSCW+FS+ +VE + + +NK LSEQ LV+CD M
Sbjct: 232 NWARTDAVSPTKDQGDHCGSCWAFSSIASVESLYRLYKNKSYFLSEQELVNCDKSSM--- 288
Query: 182 GEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMI 241
GC GGL A Y I + G+ ES PYT + C + N I + +++
Sbjct: 289 -------GCAGGLPITALEY-IHSKGVSFESEVPYTGIV-SPCKPSIKN-KVFIDSISIL 338
Query: 242 PKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFR 301
N+ V ++S + IA E + Y GG+F C L+H +L+VG +
Sbjct: 339 KGNDVVNKSLVISPTVVGIAV-TKELKLYSGGIFTGKCG-GELNHAVLLVGEGVDH---E 393
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRR---GKNTCGVSNF 337
M YWI+KNSWG DWGE G++ L+R G + CG+ F
Sbjct: 394 TGMRYWIIKNSWGEDWGENGFLRLQRTKKGLDKCGILTF 432
>sp|P14518|BROM_ANACO BROMELAIN, STEM
Length = 212
Score = 146 bits (365), Expect = 6e-35
Identities = 81/224 (36%), Positives = 115/224 (51%), Gaps = 27/224 (12%)
Query: 117 SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
++P + DWR GAVT VKNQ CG+CW+F+ VE + I + L LSEQ ++DC
Sbjct: 1 AVPQSIDWRDYGAVTSVKNQNPCGACWAFAAIATVESIYKIKKGILEPLSEQQVLDC--- 57
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
A GC GG + A+ +II N G+ + + YPY A GT C + A I+
Sbjct: 58 --------AKGYGCKGGWEFRAFEFIISNKGVASGAIYPYKAAKGT-CKTDGVPNSAYIT 108
Query: 237 NFTMIPKNETVMAGYIVSTGPLAIAADA-VEWQFYIGGVFDIPCNPNSLDHGILIVGYSA 295
+ +P+N Y VS P+ +A DA +Q+Y GVF+ PC SL+H + +GY
Sbjct: 109 GYARVPRNNESSMMYAVSKQPITVAVDANANFQYYKSGVFNGPCG-TSLNHAVTAIGYGQ 167
Query: 296 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR----GKNTCGVS 335
+ I+ K WGA WGE GYI + R CG++
Sbjct: 168 DSIIYPK---------KWGAKWGEAGYIRMARDVSSSSGICGIA 202
>sp|P22497|CYSP_THEPA CYSTEINE PROTEINASE PRECURSOR
Length = 439
Score = 145 bits (363), Expect = 1e-34
Identities = 104/343 (30%), Positives = 159/343 (46%), Gaps = 64/343 (18%)
Query: 24 EEQSQFLEFQDKFNKKYS-HEEYLERFEIFKSNLGKIEELNLIAINHKADTKF--GVNKF 80
E +F EF K+N++++ +E L R F+SN +++E K D + G+N+F
Sbjct: 119 EVYREFEEFNSKYNRRHATQQERLNRLVTFRSNYLEVKE-------QKGDEPYVKGINRF 171
Query: 81 ADLSSDEF--------------------------KNYYLNNKEAIFTDDLPVADYLDDEF 114
+DL+ EF K Y N K+A+ TD+ D +
Sbjct: 172 SDLTEREFYKLFPVMKPPKATYSNGYYLLSHMANKTYLKNLKKALNTDE-------DVDL 224
Query: 115 INSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCD 174
DWR +VT VK+Q CG CW+FST G+VEG + +K LS Q L+DCD
Sbjct: 225 AKLTGENLDWRRSSSVTSVKDQSNCGGCWAFSTVGSVEGYYMSHFDKSYELSVQELLDCD 284
Query: 175 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAK 234
+ GC GGL +AY Y+ K G+ + P+ + +C+ A
Sbjct: 285 ----------SFSNGCQGGLLESAYEYVRKY-GLVSAKDLPF-VDKARRCSVPKAK-KVS 331
Query: 235 ISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYS 294
+ ++ + K + VM + S+ + + E Y GVF C SL+H +++VG
Sbjct: 332 VPSYHVF-KGKEVMTRSLTSSPCSVYLSVSPELAKYKSGVFTGECG-KSLNHAVVLVGEG 389
Query: 295 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR---GKNTCGV 334
++ YW+V+NSWG DWGE GY+ L R G + CGV
Sbjct: 390 YDEVTKKR---YWVVQNSWGTDWGENGYMRLERTNMGTDKCGV 429
>sp|P16311|MMAL_DERFA MAJOR MITE FECAL ALLERGEN DER F 1 PRECURSOR (DER F I)
Length = 321
Score = 144 bits (359), Expect = 3e-34
Identities = 116/346 (33%), Positives = 158/346 (45%), Gaps = 48/346 (13%)
Query: 7 FVLAVFTVFVSSRGIP-PEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLI 65
FVLA+ ++ V S P F EF+ FNK Y+ +E E+ + N +E L +
Sbjct: 3 FVLAIASLLVLSTVYARPASIKTFEEFKKAFNKNYAT---VEEEEVARKNF--LESLKYV 57
Query: 66 AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEF----INSI--P 119
N K +N +DLS DEFKN YL + EA + L L+ E INS+ P
Sbjct: 58 EAN-----KGAINHLSDLSLDEFKNRYLMSAEAF--EQLKTQFDLNAETSACRINSVNVP 110
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
+ D R+ VTP++ QG CGSCW+FS E + +N + LSEQ LVDC
Sbjct: 111 SELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDC------ 164
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
A GC+G P YI +NG ++ E SYPY A NS + G ISN+
Sbjct: 165 -----ASQHGCHGDTIPRGIEYIQQNGVVE-ERSYPYVAREQRCRRPNSQHYG--ISNYC 216
Query: 240 MIPKNETVMAGYIVSTGPLAIAA-----DAVEWQFYIGGVF---DIPCNPNSLDHGILIV 291
I + ++ AIA D +Q Y G D PN H + IV
Sbjct: 217 QIYPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNY--HAVNIV 274
Query: 292 GYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNF 337
GY + + YWIV+NSW WG+ GY Y + G N + +
Sbjct: 275 GYGS-----TQGDDYWIVRNSWDTTWGDSGYGYFQAGNNLMMIEQY 315
>sp|P25805|CYSP_PLAFA THROPHOZOITE CYSTEINE PROTEINASE PRECURSOR (TCP)
Length = 569
Score = 144 bits (359), Expect = 3e-34
Identities = 102/363 (28%), Positives = 167/363 (45%), Gaps = 62/363 (17%)
Query: 27 SQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
S+F +F + NK Y + +E + +FEIFK N I+ N +N A K VN+F+D S
Sbjct: 223 SKFFKFMKEHNKVYKNIDEQMRKFEIFKINYISIKNHN--KLNKNAMYKKKVNQFSDYSE 280
Query: 86 DEFKNY--------------YLNNKEAIFTDDLPVADYL------DDEFINSIPTAFDWR 125
+E K Y Y E D++ ++++ + + + +P D+R
Sbjct: 281 EELKEYFKTLLHVPNHMIEKYSKPFENHLKDNILISEFYTNGKRNEKDIFSKVPEILDYR 340
Query: 126 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEA 185
+G V K+QG CGSCW+F++ GN+E ++S SEQ +VDC +
Sbjct: 341 EKGIVHEPKDQGLCGSCWAFASVGNIESVFAKKNKNILSFSEQEVVDCSKD--------- 391
Query: 186 CDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNE 245
+ GC+GG ++ Y+++N + Y Y A+ C +S+ + +N+
Sbjct: 392 -NFGCDGGHPFYSFLYVLQN-ELCLGDEYKYKAKDDMFCLNYRCKRKVSLSSIGAVKENQ 449
Query: 246 TVMAGYIVSTGPLAIAADA-VEWQFYIGGVFDIPCNPNSLDHGILIVGY----------- 293
++A + GPL++ ++ Y GV++ C+ L+H +L+VGY
Sbjct: 450 LILA--LNEVGPLSVNVGVNNDFVAYSEGVYNGTCS-EELNHSVLLVGYGQVEKTKLNYN 506
Query: 294 ---SAKNTIFRKNMP------YWIVKNSWGADWGEQGYIYLRRGKN----TCGVSNFVST 340
NT N P YWI+KNSW WGE G++ L R KN CG+ V
Sbjct: 507 NKIQTYNTKENSNQPDDNIIYYWIIKNSWSKKWGENGFMRLSRNKNGDNVFCGIGEEVFY 566
Query: 341 SII 343
I+
Sbjct: 567 PIL 569
>sp|P42666|CYSP_PLAVI CYSTEINE PROTEINASE PRECURSOR
Length = 583
Score = 132 bits (329), Expect = 1e-30
Identities = 102/367 (27%), Positives = 165/367 (44%), Gaps = 86/367 (23%)
Query: 27 SQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
S+F F +K+ + Y E +E+++ FK N KI++ N K VN+F+D S
Sbjct: 235 SKFFNFMNKYKRSYKDINEQMEKYKNFKMNYLKIKKHN----ETNQMYKMKVNQFSDYSK 290
Query: 86 DEFKNYYLNNKEAIFTDDLPVADYLDDEFI------------------------NSIPTA 121
+F++Y F +P+ D+L +++ +P
Sbjct: 291 KDFESY--------FRKLVPIPDHLKKKYVVPFSSMNNGKGKNVVTSSSGANLLADVPEI 342
Query: 122 FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNK-LVSLSEQNLVDCDHECMEY 180
D+R +G V K+QG CGSCW+F++ GNVE + NK +++LSEQ +VDC
Sbjct: 343 LDYREKGIVHEPKDQGLCGSCWAFASVGNVECMYAKEHNKTILTLSEQEVVDC------- 395
Query: 181 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQC-NFNSANIGAKISNFT 239
+ GC+GG ++ Y I+N GI Y Y A C N+ N +S+
Sbjct: 396 ---SKLNFGCDGGHPFYSFIYAIEN-GICMGDDYKYKAMDNLFCLNYRCKN-KVTLSSVG 450
Query: 240 MIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYS--AK 296
+ +NE + A + GP+++ ++ FY GG+F+ C L+H +L+VGY
Sbjct: 451 GVKENELIRA--LNEVGPVSVNVGVTDDFSFYGGGIFNGTCT-EELNHSVLLVGYGQVQS 507
Query: 297 NTIFRKN-------------------------MPYWIVKNSWGADWGEQGYIYLRRGKN- 330
+ IF++ YWI+KNSW WGE G++ + R K
Sbjct: 508 SKIFQEKNAYDDASGVTKKGALSYPSKADDGIQYYWIIKNSWSKFWGENGFMRISRNKEG 567
Query: 331 ---TCGV 334
CG+
Sbjct: 568 DNVFCGI 574
>sp|P08176|MMAL_DERPT MAJOR MITE FECAL ALLERGEN DER P 1 PRECURSOR (DER P I)
Length = 320
Score = 123 bits (305), Expect = 7e-28
Identities = 110/338 (32%), Positives = 151/338 (44%), Gaps = 51/338 (15%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
MK++L + V +R P F E++ FNK Y+ E E + N +E
Sbjct: 1 MKIVLAIASLLALSAVYAR---PSSIKTFEEYKKAFNKSYAT---FEDEEAARKNF--LE 52
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEF----IN 116
+ + N A +N +DLS DEFKN +L + EA + L L+ E IN
Sbjct: 53 SVKYVQSNGGA-----INHLSDLSLDEFKNRFLMSAEAF--EHLKTQFDLNAETNACSIN 105
Query: 117 -SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 175
+ P D R VTP++ QG CGSCW+FS E + +N+ + L+EQ LVDC
Sbjct: 106 GNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDC-- 163
Query: 176 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKI 235
A GC+G P YI NG +Q ES Y Y A + N+ G I
Sbjct: 164 ---------ASQHGCHGDTIPRGIEYIQHNGVVQ-ESYYRYVAREQSCRRPNAQRFG--I 211
Query: 236 SNFTMI-PKNETVMAGYIVSTGPLAIAA-----DAVEWQFYIGGVF---DIPCNPNSLDH 286
SN+ I P N + + T AIA D ++ Y G D PN H
Sbjct: 212 SNYCQIYPPNVNKIREALAQTHS-AIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNY--H 268
Query: 287 GILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIY 324
+ IVGYS + + YWIV+NSW +WG+ GY Y
Sbjct: 269 AVNIVGYSN-----AQGVDYWIVRNSWDTNWGDNGYGY 301
>sp|P80067|CATC_RAT DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
(CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
Length = 462
Score = 117 bits (291), Expect = 3e-26
Identities = 81/255 (31%), Positives = 128/255 (49%), Gaps = 32/255 (12%)
Query: 105 PVADYLDDEFINSIPTAFDWRT-RGA--VTPVKNQGQCGSCWSFSTTGNVEGQHFISQNK 161
P+ D + + + S+P ++DWR RG V+PV+NQ CGSC+SF++ G +E + I N
Sbjct: 218 PITDEIQQQIL-SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASIGMLEARIRILTNN 276
Query: 162 LVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAE 219
+ LS Q +V C +GC+GG ++ G+ E+ +PYTA
Sbjct: 277 SQTPILSPQEVVSCSPYA----------QGCDGGFPYLIAGKYAQDFGVVEENCFPYTA- 325
Query: 220 TGTQCNFNSANIGAKISNFTMIPK-----NETVMAGYIVSTGPLAIAADAVE-WQFYIGG 273
T C + S + + NE +M +V GP+A+A + + + Y G
Sbjct: 326 TDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSG 385
Query: 274 VF-----DIPCNPNSL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR 327
++ P NP L +H +L+VGY K+ + + YWIVKNSWG+ WGE GY +RR
Sbjct: 386 IYHHTGLSDPFNPFELTNHAVLLVGYG-KDPV--TGLDYWIVKNSWGSQWGESGYFRIRR 442
Query: 328 GKNTCGVSNFVSTSI 342
G + C + + +I
Sbjct: 443 GTDECAIESIAMAAI 457
>sp|P97821|CATC_MOUSE DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
(CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
Length = 462
Score = 116 bits (287), Expect = 8e-26
Identities = 90/331 (27%), Positives = 156/331 (46%), Gaps = 42/331 (12%)
Query: 34 DKFNKKYSH-----EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEF 88
+K N +H E Y ER ++ N ++ +N + K+ T ++ +S +
Sbjct: 147 EKVNMNAAHLGGLQERYSER--LYTHNHNFVKAINTV---QKSWTATAYKEYEKMSLRDL 201
Query: 89 KNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRT-RGA--VTPVKNQGQCGSCWSF 145
+++ P+ D + + +N +P ++DWR +G V+PV+NQ CGSC+SF
Sbjct: 202 IRRSGHSQRIPRPKPAPMTDEIQQQILN-LPESWDWRNVQGVNYVSPVRNQESCGSCYSF 260
Query: 146 STTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
++ G +E + I N + LS Q +V C +GC+GG
Sbjct: 261 ASMGMLEARIRILTNNSQTPILSPQEVVSCSPYA----------QGCDGGFPYLIAGKYA 310
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPK-----NETVMAGYIVSTGPL 258
++ G+ ES +PYTA+ + C + S++ + NE +M +V GP+
Sbjct: 311 QDFGVVEESCFPYTAKD-SPCKPRENCLRYYSSDYYYVGGFYGGCNEALMKLELVKHGPM 369
Query: 259 AIAADAVE-WQFYIGGVF-----DIPCNPNSL-DHGILIVGYSAKNTIFRKNMPYWIVKN 311
A+A + + + Y G++ P NP L +H +L+VGY + YWI+KN
Sbjct: 370 AVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGRDPVT---GIEYWIIKN 426
Query: 312 SWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
SWG++WGE GY +RRG + C + + +I
Sbjct: 427 SWGSNWGESGYFRIRRGTDECAIESIAVAAI 457
>sp|P53634|CATC_HUMAN DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
(CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
Length = 463
Score = 113 bits (281), Expect = 4e-25
Identities = 75/236 (31%), Positives = 113/236 (47%), Gaps = 31/236 (13%)
Query: 118 IPTAFDWRTRGA---VTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVD 172
+PT++DWR V+PV+NQ CGSC+SF++ G +E + I N + LS Q +V
Sbjct: 231 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 290
Query: 173 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG 232
C +GC GG ++ G+ E+ +PYT T + C
Sbjct: 291 CSQYA----------QGCEGGFPYLIAGKYAQDFGLVEEACFPYTG-TDSPCKMKEDCFR 339
Query: 233 AKISNFTMIPK-----NETVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDI-----PCNP 281
S + + NE +M +V GP+A+A + + + Y G++ P NP
Sbjct: 340 YYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNP 399
Query: 282 NSL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 336
L +H +L+VGY + M YWIVKNSWG WGE GY +RRG + C + +
Sbjct: 400 FELTNHAVLLVGYGTDSA---SGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIES 452
>sp|Q26563|CATC_SCHMA CATHEPSIN C PRECURSOR
Length = 454
Score = 113 bits (279), Expect = 7e-25
Identities = 75/242 (30%), Positives = 113/242 (45%), Gaps = 35/242 (14%)
Query: 117 SIPTAFDWRT-----RGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQN 169
++P FDW + R VTP++NQG CGSC++ + +E + + N + LS Q
Sbjct: 217 NLPLEFDWTSPPDGSRSPVTPIRNQGICGSCYASPSAAALEARIRLVSNFSEQPILSPQT 276
Query: 170 LVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSA 229
+VDC EGCNGG ++ G+ + PYT E +C +
Sbjct: 277 VVDCS----------PYSEGCNGGFPFLIAGKYGEDFGLPQKIVIPYTGEDTGKCTVSKN 326
Query: 230 NIGAKISNFTMI-----PKNETVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPC---- 279
++++ I NE +M ++S GP + + E +QFY G++
Sbjct: 327 CTRYYTTDYSYIGGYYGATNEKLMQLELISNGPFPVGFEVYEDFQFYKEGIYHHTTVQTD 386
Query: 280 ----NPNSL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGV 334
NP L +H +L+VGY PYW VKNSWG +WGEQGY + RG + CGV
Sbjct: 387 HYNFNPFELTNHAVLLVGYGVDKL---SGEPYWKVKNSWGVEWGEQGYFRILRGTDECGV 443
Query: 335 SN 336
+
Sbjct: 444 ES 445
>sp|P25773|CATL_FELCA CATHEPSIN L (PROGESTERONE-DEPENDENT PROTEIN) (PDP)
Length = 139
Score = 113 bits (279), Expect = 7e-25
Identities = 55/141 (39%), Positives = 84/141 (59%), Gaps = 5/141 (3%)
Query: 192 GGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGY 251
GGL +A+ Y+ NGG+ +E SYPY A+ G C + N A ++++ IP E +
Sbjct: 1 GGLIDDAFQYVKDNGGLDSEESYPYHAQ-GDSCKYRPENSVANVTDYWDIPSKENELMIT 59
Query: 252 IVSTGPLAIAADAV--EWQFYIGGVF-DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWI 308
+ + GP++ A DA ++FY G++ D C+ +DHG+L+VGY A T +N YWI
Sbjct: 60 LAAVGPISAAIDASLDTFRFYKEGIYYDPSCSSEDVDHGVLVVGYGADGTE-TENKKYWI 118
Query: 309 VKNSWGADWGEQGYIYLRRGK 329
+KNSWG DWG GYI + + +
Sbjct: 119 IKNSWGTDWGMDGYIKMAKDR 139
>sp|P25780|EUM1_EURMA MITE GROUP I ALLERGEN EUR M 1 (EUR M I)
Length = 211
Score = 105 bits (260), Expect = 1e-22
Identities = 73/222 (32%), Positives = 102/222 (45%), Gaps = 29/222 (13%)
Query: 117 SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
S+P+ D R+ VTP++ QG CGSCW+FS + E + +N + L+EQ LVDC
Sbjct: 10 SLPSELDLRSLRTVTPIRMQGGCGSCWAFSGVASTESAYLAYRNMSLDLAEQELVDC--- 66
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
A GC+G P YI +NG +Q E YPY A + N+ G K
Sbjct: 67 --------ASQNGCHGDTIPRGIEYIQQNGVVQ-EHYYPYVAREQSCHRPNAQRYGLK-- 115
Query: 237 NFTMIPKNETVMAGYIVSTGPLAIAA-----DAVEWQFYIGGVF---DIPCNPNSLDHGI 288
N+ I ++ ++ A+A D ++ Y G D PN H +
Sbjct: 116 NYCQISPPDSNKIRQALTQTHTAVAVIIGIKDLNAFRHYDGRTIMQHDNGYQPNY--HAV 173
Query: 289 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKN 330
IVGY NT + + YWIV+NSW WG+ GY Y N
Sbjct: 174 NIVGYG--NT---QGVDYWIVRNSWDTTWGDNGYGYFAANIN 210
>sp|Q23894|CYS3_DICDI CYSTEINE PROTEINASE 3 (CYSTEINE PROTEINASE II)
Length = 151
Score = 95.6 bits (234), Expect = 1e-19
Identities = 61/157 (38%), Positives = 86/157 (53%), Gaps = 17/157 (10%)
Query: 41 SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIF 100
+H+E++ R+E FK N+ + N + + T G+N+ ADLS++E++ YL + I
Sbjct: 1 THKEFMPRYEEFKKNMDYVHNWN----SKGSKTVLGLNQHADLSNEEYRLNYLGTRAHIK 56
Query: 101 TDDLPVADY---LDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFI 157
+ + L+ P DWR + AVTPVK+QGQCGSC STTG+VEG I
Sbjct: 57 LNGYHKRNLGLRLNRPHFKQ-PLNVDWREKDAVTPVKDQGQCGSC-IISTTGSVEGVTAI 114
Query: 158 SQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGL 194
KLVSLSEQN++ +EGCNGGL
Sbjct: 115 KTGKLVSLSEQNILRL--------SSSFGNEGCNGGL 143
>sp|P43508|CPR4_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 4 PRECURSOR
Length = 335
Score = 94.4 bits (231), Expect = 3e-19
Identities = 82/300 (27%), Positives = 129/300 (42%), Gaps = 60/300 (20%)
Query: 82 DLSSDEFKNYYLNNK-EAIFTDDLPVADYLDDEFINSIPTAFDWRTRG----AVTPVKNQ 136
D++ ++ K + + A T D+ V + +E ++IP FD RT+ ++ +++Q
Sbjct: 46 DITIEQVKKRLMRTEFVAPHTPDVEVVKHDINE--DTIPATFDARTQWPNCMSINNIRDQ 103
Query: 137 GQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGL 194
CGSCW+F+ + I+ N V+ LS ++++ C C C GC GG
Sbjct: 104 SDCGSCWAFAAAEAASDRFCIASNGAVNTLLSAEDVLSC---CSN------CGYGCEGGY 154
Query: 195 QPNAYNYIIKNGGIQTESSY-------PYT-AETG------------------------- 221
NA+ Y++K+G T SY PY+ A G
Sbjct: 155 PINAWKYLVKSG-FCTGGSYEAQFGCKPYSLAPCGETVGNVTWPSCPDDGYDTPACVNKC 213
Query: 222 TQCNFNSANIGAKISNFTM--IPKNETVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIP 278
T N+N A K T + K + + I++ GP+ A E + Y GV+
Sbjct: 214 TNKNYNVAYTADKHFGSTAYAVGKKVSQIQAEIIAHGPVEAAFTVYEDFYQYKTGVYVHT 273
Query: 279 CNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFV 338
H I I+G+ N PYW+V NSW +WGE GY + RG N CG+ + V
Sbjct: 274 TGQELGGHAIRILGWGTDN-----GTPYWLVANSWNVNWGENGYFRIIRGTNECGIEHAV 328
>sp|P05993|PAP5_CARPA CYSTEINE PROTEINASE (CLONE PLBPC13)
Length = 96
Score = 90.5 bits (221), Expect = 5e-18
Identities = 43/87 (49%), Positives = 55/87 (62%), Gaps = 2/87 (2%)
Query: 256 GPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN--TIFRKNMPYWIVKNSW 313
GPLA+A +A Q YIGGV L+HG+L+VGY + I K PYW++KNSW
Sbjct: 1 GPLAVAINAAYMQTYIGGVSCPYICSRRLNHGVLLVGYGSAGYAPIRLKEKPYWVIKNSW 60
Query: 314 GADWGEQGYIYLRRGKNTCGVSNFVST 340
G +WGE GY + RG+N CGV + VST
Sbjct: 61 GENWGENGYYKICRGRNICGVDSMVST 87
>sp|P25807|CYS1_CAEEL GUT-SPECIFIC CYSTEINE PROTEINASE PRECURSOR
Length = 329
Score = 90.5 bits (221), Expect = 5e-18
Identities = 69/288 (23%), Positives = 118/288 (40%), Gaps = 46/288 (15%)
Query: 82 DLSSDEFKNYYLNNK-EAIFTDDLPVADYLDDEFINSIPTAFDWRTRGA----VTPVKNQ 136
+++ +E K ++ K A +D++ + + + S+P FD RT+ + + +++Q
Sbjct: 50 EITEEEMKFKLMDGKYAAAHSDEIRATE--QEVVLASVPATFDSRTQWSECKSIKLIRDQ 107
Query: 137 GQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGL 194
CGSCW+F + + I +S +L+ C C +C GC GG
Sbjct: 108 ATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLLSC---C-----GSSCGNGCEGGY 159
Query: 195 QPNAYNY-----IIKNGGIQTESSYPY--------------TAETGTQCNFNSANIGAKI 235
A + ++ G PY T C + AK
Sbjct: 160 PIQALRWWDSKGVVTGGDYHGAGCKPYPIAPCTSGNCPESKTPSCSMSCQSGYSTAYAKD 219
Query: 236 SNFTM----IPKNETVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILI 290
+F + +PKN + I + GP+ A E + Y GV+ H I I
Sbjct: 220 KHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDFYKYKSGVYKHTAGKYLGGHAIKI 279
Query: 291 VGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFV 338
+G+ ++ PYW+V NSWG +WGE G+ + RG + CG+ + V
Sbjct: 280 IGWGTES-----GSPYWLVANSWGVNWGESGFFKIYRGDDQCGIESAV 322
>sp|P43509|CPR5_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 5 PRECURSOR
Length = 344
Score = 89.3 bits (218), Expect = 1e-17
Identities = 69/272 (25%), Positives = 113/272 (41%), Gaps = 55/272 (20%)
Query: 108 DYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLV 163
D + E ++IP FD W ++ +++Q CGSCW+F+ + + I+ N V
Sbjct: 72 DIVATEVSDAIPDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAV 131
Query: 164 S--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSY------- 214
+ LS ++L+ C G +C GC GG A+ + +K+G + T SY
Sbjct: 132 NTLLSSEDLLSC------CTGMFSCGNGCEGGYPIQAWKWWVKHG-LVTGGSYETQFGCK 184
Query: 215 -------------------PYTAETGTQC--------NFNSANIGAKISNFTM--IPKNE 245
P E +C N+ + + K T + K
Sbjct: 185 PYSIAPCGETVNGVKWPACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKV 244
Query: 246 TVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNM 304
+ I++ GP+ +A E + Y GV+ + H + I+G+ N
Sbjct: 245 EQIQTEILTNGPIEVAFTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDN-----GT 299
Query: 305 PYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 336
PYW+V NSW WGE+GY + RG N CG+ +
Sbjct: 300 PYWLVANSWNVAWGEKGYFRIIRGLNECGIEH 331
>sp|P00787|CATB_RAT CATHEPSIN B PRECURSOR (CATHEPSIN B1) (RSG-2)
Length = 339
Score = 87.8 bits (214), Expect = 3e-17
Identities = 68/264 (25%), Positives = 114/264 (42%), Gaps = 51/264 (19%)
Query: 117 SIPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL--SEQNL 170
++P +FD W + +++QG CGSCW+F + + I N V++ S ++L
Sbjct: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138
Query: 171 VDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK----NGGIQTE--------------- 211
+ C C C +GCNGG A+N+ + +GG+
Sbjct: 139 LTC---C-----GIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHH 190
Query: 212 ---SSYPYTAETGT-QCN------FNSANIGAKISNFTM--IPKNETVMAGYIVSTGPLA 259
S P T E T +CN ++++ K +T + +E + I GP+
Sbjct: 191 VNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVE 250
Query: 260 IAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 318
A ++ Y GV+ H I I+G+ +N + PYW+V NSW DWG
Sbjct: 251 GAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGV-----PYWLVANSWNVDWG 305
Query: 319 EQGYIYLRRGKNTCGVSNFVSTSI 342
+ G+ + RG+N CG+ + + I
Sbjct: 306 DNGFFKILRGENHCGIESEIVAGI 329
>sp|P07688|CATB_BOVIN CATHEPSIN B PRECURSOR
Length = 335
Score = 87.0 bits (212), Expect = 5e-17
Identities = 67/259 (25%), Positives = 103/259 (38%), Gaps = 55/259 (21%)
Query: 118 IPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL---SEQNL 170
+P +FD W + +++QG CGSCW+F + + I N V++ +E L
Sbjct: 80 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 139
Query: 171 VDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ--------------------- 209
C EC +GCNGG A+N+ K G +
Sbjct: 140 TCCGGEC---------GDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHH 190
Query: 210 -TESSYPYTAETGT-QCNFNSANIGAKIS---------NFTMIPKNETVMAGYIVSTGPL 258
S P T E T +CN + G S + + NE + I GP+
Sbjct: 191 VNGSRPPCTGEGDTPKCN-KTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPV 249
Query: 259 AIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 317
A ++ Y GV+ H I I+G+ +N PYW+V NSW DW
Sbjct: 250 EGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVEN-----GTPYWLVGNSWNTDW 304
Query: 318 GEQGYIYLRRGKNTCGVSN 336
G+ G+ + RG++ CG+ +
Sbjct: 305 GDNGFFKILRGQDHCGIES 323
>sp|P07858|CATB_HUMAN CATHEPSIN B PRECURSOR (CATHEPSIN B1) (APP SECRETASE)
Length = 339
Score = 85.8 bits (209), Expect = 1e-16
Identities = 70/285 (24%), Positives = 110/285 (38%), Gaps = 63/285 (22%)
Query: 96 KEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNV 151
+ +FT+DL +P +FD W + +++QG CGSCW+F +
Sbjct: 70 QRVMFTEDL------------KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAI 117
Query: 152 EGQHFISQNKLVSL--SEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ 209
+ I N VS+ S ++L+ C C C +GCNGG A+N+ + G +
Sbjct: 118 SDRICIHTNAHVSVEVSAEDLLTC---C-----GSMCGDGCNGGYPAEAWNFWTRKGLVS 169
Query: 210 ----------------------TESSYPYTAETGTQCNFNSANIGAKIS---------NF 238
S P T E T G + N
Sbjct: 170 GGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNS 229
Query: 239 TMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN 297
+ +E + I GP+ A ++ Y GV+ H I I+G+ +N
Sbjct: 230 YSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVEN 289
Query: 298 TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
PYW+V NSW DWG+ G+ + RG++ CG+ + V I
Sbjct: 290 -----GTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGI 329
>sp|P43157|CYSP_SCHJA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECURSOR (ANTIGEN SJ31)
Length = 342
Score = 84.7 bits (206), Expect = 3e-16
Identities = 66/268 (24%), Positives = 111/268 (40%), Gaps = 59/268 (22%)
Query: 118 IPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLV 171
IP+ FD W +++ +++Q +CGSCW+F + + I + LS +L+
Sbjct: 90 IPSQFDSRKKWPHCKSISQIRDQSRCGSCWAFGAVEAMTDRICIQSGGGQSAELSALDLI 149
Query: 172 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGI---------------------QT 210
C C + C +GC GG A++Y +K G + T
Sbjct: 150 SC---CKD------CGDGCQGGFPGVAWDYWVKRGIVTGGSKENHTGCQPYPFPKCEHHT 200
Query: 211 ESSYP-------------YTAETGTQCNFNS-ANIGAKISNFTMIPKNETVMAGYIVSTG 256
+ YP T + G + + + G + N + NE V+ I+ G
Sbjct: 201 KGKYPACGTKIYKTPQCKQTCQKGYKTPYEQDKHYGDESYN---VQNNEKVIQRDIMMYG 257
Query: 257 PLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGA 315
P+ A D E + Y G++ H I I+G+ + K PYW++ NSW
Sbjct: 258 PVEAAFDVYEDFLNYKSGIYRHVTGSIVGGHAIRIIGWGVE-----KRTPYWLIANSWNE 312
Query: 316 DWGEQGYIYLRRGKNTCGVSNFVSTSII 343
DWGE+G + RG++ C + + V +I
Sbjct: 313 DWGEKGLFRMVRGRDECSIESDVVAGLI 340
>sp|P25792|CYSP_SCHMA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECURSOR (ANTIGEN SM31)
Length = 340
Score = 84.7 bits (206), Expect = 3e-16
Identities = 66/260 (25%), Positives = 109/260 (41%), Gaps = 53/260 (20%)
Query: 118 IPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLV 171
IP+ FD W ++ +++Q +CGSCWSF + + I + V LS +L+
Sbjct: 89 IPSNFDSRKKWPGCKSIATIRDQSRCGSCWSFGAVEAMSDRSCIQSGGKQNVELSAVDLL 148
Query: 172 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTA---ETGTQCNFNS 228
C C E+C GC GG+ A++Y +K G + S +T +C ++
Sbjct: 149 TC---C------ESCGLGCEGGILGPAWDYWVKEGIVTASSKENHTGCEPYPFPKCEHHT 199
Query: 229 AN----IGAKISN---------------FTM----------IPKNETVMAGYIVSTGPLA 259
G+KI N +T + +E + I+ GP+
Sbjct: 200 KGKYPPCGSKIYNTPRCKQTCQRKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVE 259
Query: 260 IAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 318
+ E + Y G++ H I I+G+ +N PYW++ NSW DWG
Sbjct: 260 ASFTVYEDFLNYKSGIYKHITGEALGGHAIRIIGWGVEN-----KTPYWLIANSWNEDWG 314
Query: 319 EQGYIYLRRGKNTCGVSNFV 338
E GY + RG++ C + + V
Sbjct: 315 ENGYFRIVRGRDECSIESEV 334
>sp|P10605|CATB_MOUSE CATHEPSIN B PRECURSOR (CATHEPSIN B1)
Length = 339
Score = 83.9 bits (204), Expect = 5e-16
Identities = 69/265 (26%), Positives = 111/265 (41%), Gaps = 55/265 (20%)
Query: 118 IPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL--SEQNLV 171
+P FD W + +++QG CGSCW+F + + I N V++ S ++L+
Sbjct: 80 LPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLL 139
Query: 172 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK----NGGIQTE---------------- 211
C C C +GCNGG A+++ K +GG+
Sbjct: 140 TC---C-----GIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHV 191
Query: 212 --SSYPYTAETGT-QCNFNSANIGAKIS----------NFTMIPKNETVMAGYIVSTGPL 258
S P T E T +CN S G S ++++ + +MA I GP+
Sbjct: 192 NGSRPPCTGEGDTPRCN-KSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAE-IYKNGPV 249
Query: 259 AIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 317
A ++ Y GV+ H I I+G+ +N + PYW+ NSW DW
Sbjct: 250 EGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGV-----PYWLAANSWNLDW 304
Query: 318 GEQGYIYLRRGKNTCGVSNFVSTSI 342
G+ G+ + RG+N CG+ + + I
Sbjct: 305 GDNGFFKILRGENHCGIESEIVAGI 329
>sp|P43510|CPR6_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6 PRECURSOR
Length = 379
Score = 83.5 bits (203), Expect = 6e-16
Identities = 72/265 (27%), Positives = 114/265 (42%), Gaps = 61/265 (23%)
Query: 118 IPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNK--LVSLSEQNLV 171
IP +FD W ++ +++Q CGSCW+F + + I+ + V+LS +L+
Sbjct: 105 IPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLL 164
Query: 172 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ------CN 225
C C ++C GCNGG A+ Y +K+G I T S+Y TA G + C
Sbjct: 165 SC---C------KSCGFGCNGGDPLAAWRYWVKDG-IVTGSNY--TANNGCKPYPFPPCE 212
Query: 226 FNSANIGAK----------------ISNFTMIPKNETVMAGY---------------IVS 254
+S +S++T +E G +++
Sbjct: 213 HHSKKTHFDPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMT 272
Query: 255 TGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSW 313
GPL IA + E + Y GGV+ H + ++G+ + I PYW V NSW
Sbjct: 273 HGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGI-----PYWTVANSW 327
Query: 314 GADWGEQGYIYLRRGKNTCGVSNFV 338
DWGE G+ + RG + CG+ + V
Sbjct: 328 NTDWGEDGFFRILRGVDECGIESGV 352
>sp|P43233|CATB_CHICK CATHEPSIN B PRECURSOR (CATHEPSIN B1)
Length = 340
Score = 83.5 bits (203), Expect = 6e-16
Identities = 69/278 (24%), Positives = 112/278 (39%), Gaps = 56/278 (20%)
Query: 100 FTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQ 159
F +D+ + D D T W ++ +++QG CGSCW+F + + +
Sbjct: 74 FAEDMDLPDTFD--------TRKQWPNCPTISEIRDQGSCGSCWAFGAVEAISDRICVHT 125
Query: 160 NKLVSL--SEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ-------- 209
N VS+ S ++L+ C C G E C GCNGG A+ Y + G +
Sbjct: 126 NAKVSVEVSAEDLLSC---C----GFE-CGMGCNGGYPSGAWRYWTERGLVSGGLYDSHV 177
Query: 210 --------------TESSYPYTAETGT--QCN------FNSANIGAKISNFTM--IPKNE 245
S P T E G +C+ ++ + K T +P++E
Sbjct: 178 GCRAYTIPPCEHHVNGSRPPCTGEGGETPRCSRHCEPGYSPSYKEDKHYGITSYGVPRSE 237
Query: 246 TVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNM 304
+ I GP+ A E + Y GV+ H I I+G+ +N
Sbjct: 238 KEIMAEIYKNGPVEGAFIVYEDFLMYKSGVYQHVSGEQVGGHAIRILGWGVEN-----GT 292
Query: 305 PYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
PYW+ NSW DWG G+ + RG++ CG+ + + +
Sbjct: 293 PYWLAANSWNTDWGITGFFKILRGEDHCGIESEIVAGV 330
>sp|P25802|CYS1_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PRECURSOR
Length = 341
Score = 76.1 bits (184), Expect = 1e-13
Identities = 65/270 (24%), Positives = 104/270 (38%), Gaps = 54/270 (20%)
Query: 103 DLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFIS 158
D V D +E + IP ++D W ++ + +Q CGSCW+ S+ + + I+
Sbjct: 76 DEEVEDEELEENNDDIPESYDPRIQWANCSSLFHIPDQANCGSCWAVSSAAAMSDRICIA 135
Query: 159 QN--KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNY-----IIKNGGIQTE 211
K V +S Q++V C C C +GC GG +A+ + ++ G T+
Sbjct: 136 SKGAKQVLISAQDVVSC---CTW------CGDGCEGGWPISAFRFHADEGVVTGGDYNTK 186
Query: 212 SSY-PYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGY------------------- 251
S PY + N G + + GY
Sbjct: 187 GSCRPYEIHPCGH-HGNETYYGECVGMADTPRCKRRCLLGYPKSYPSDRYYKKAYQLKNS 245
Query: 252 -------IVSTGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKN 303
I+ GP+ E + Y G++ + H + ++G+ + K
Sbjct: 246 VKAIQKDIMKNGPVVATYTVYEDFAHYRSGIYKHKAGRKTGLHAVKVIGWGEE-----KG 300
Query: 304 MPYWIVKNSWGADWGEQGYIYLRRGKNTCG 333
PYWIV NSW DWGE G+ + RG N CG
Sbjct: 301 TPYWIVANSWHDDWGENGFFRMHRGSNDCG 330
>sp|P25793|CYS2_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 2 PRECURSOR
Length = 342
Score = 75.3 bits (182), Expect = 2e-13
Identities = 55/247 (22%), Positives = 102/247 (41%), Gaps = 50/247 (20%)
Query: 133 VKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLVDCDHECMEYEGEEACDEGC 190
+++Q CGSCW+ ST + + I+ K V++S +++ C C C +GC
Sbjct: 105 IRDQANCGSCWAVSTAAAISDRICIASKAEKQVNISATDIMTC---C-----RPQCGDGC 156
Query: 191 NGGLQPNAYNYIIKNGGIQ------TESSYPYTAET----GTQCNFNSANIGAKI----- 235
GG A+ Y I +G + + PY G + A
Sbjct: 157 EGGWPIEAWKYFIYDGVVSGGEYLTKDVCRPYPIHPCGHHGNDTYYGECRGTAPTPPCKR 216
Query: 236 -----------------SNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFD 276
+ ++ ++ + I+ GP+ +A+ AV +++ Y G++
Sbjct: 217 KCRPGVRKMYRIDKRYGKDAYIVKQSVKAIQSEILKNGPV-VASFAVYEDFRHYKSGIYK 275
Query: 277 IPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 336
H + ++G+ +N N +W++ NSW DWGE+GY + RG N CG+
Sbjct: 276 HTAGELRGYHAVKMIGWGNEN-----NTDFWLIANSWHNDWGEKGYFRIVRGSNDCGIEG 330
Query: 337 FVSTSII 343
++ I+
Sbjct: 331 TIAAGIV 337
>sp|P19092|CYS1_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PRECURSOR
Length = 342
Score = 74.5 bits (180), Expect = 3e-13
Identities = 55/247 (22%), Positives = 102/247 (41%), Gaps = 50/247 (20%)
Query: 133 VKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLVDCDHECMEYEGEEACDEGC 190
+++Q CGSCW+ ST + + I+ K V++S +++ C C C +GC
Sbjct: 105 IRDQANCGSCWAVSTAAAISDRICIASKAEKQVNISATDIMTC---C-----RPQCGDGC 156
Query: 191 NGGLQPNAYNYIIKNGGIQ------TESSYPYTAET----GTQCNFNSANIGAKI----- 235
GG A+ Y I +G + + PY G + A
Sbjct: 157 EGGWPIEAWKYFIYDGVVSGGEYLTKDVCRPYPIHPCGHHGNDTYYGECRGTAPTPPCKR 216
Query: 236 -----------------SNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFD 276
+ ++ ++ + I+ GP+ +A+ AV +++ Y G++
Sbjct: 217 KCRPGVRKMYRIDKRYGKDAYIVKQSVKAIQSEILRNGPV-VASFAVYEDFRHYKSGIYK 275
Query: 277 IPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 336
H + ++G+ +N N +W++ NSW DWGE+GY + RG N CG+
Sbjct: 276 HTAGELRGYHAVKMIGWGNEN-----NTDFWLIANSWHNDWGEKGYFRIIRGTNDCGIEG 330
Query: 337 FVSTSII 343
++ I+
Sbjct: 331 TIAAGIV 337
>sp|P43507|CPR3_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3 PRECURSOR
Length = 370
Score = 73.4 bits (177), Expect = 7e-13
Identities = 61/259 (23%), Positives = 101/259 (38%), Gaps = 49/259 (18%)
Query: 118 IPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLV 171
+P FD W + ++NQ CGSCW+F + + I N +S ++++
Sbjct: 92 LPDTFDAREKWPDCNTIKLIRNQATCGSCWAFGAAEVISDRVCIQSNGTQQPVISVEDIL 151
Query: 172 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ---------------------T 210
C C C GC GG A + +G +
Sbjct: 152 SC---C-----GTTCGYGCKGGYSIEALRFWASSGAVTGGDYGGHGCMPYSFAPCTKNCP 203
Query: 211 ESSYPYTAETGTQCNFNSA------NIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA 264
ES+ P + +T Q ++ + + GA T K+ T + I GP+ +
Sbjct: 204 ESTTP-SCKTTCQSSYKTEEYKKDKHYGASAYKVTTT-KSVTEIQTEIYHYGPVEASYKV 261
Query: 265 VE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 323
E + Y GV+ H + I+G+ +N + YW++ NSWG +GE+G+
Sbjct: 262 YEDFYHYKSGVYHYTSGKLVGGHAVKIIGWGVENGV-----DYWLIANSWGTSFGEKGFF 316
Query: 324 YLRRGKNTCGVSNFVSTSI 342
+RRG N C + V I
Sbjct: 317 KIRRGTNECQIEGNVVAGI 335
>sp|P13823|SERA_PLAFG SERINE-REPEAT ANTIGEN PROTEIN PRECURSOR (P126) (111 KD ANTIGEN)
Length = 989
Score = 70.6 bits (170), Expect = 4e-12
Identities = 61/247 (24%), Positives = 101/247 (40%), Gaps = 50/247 (20%)
Query: 133 VKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE--EACDEGC 190
V++QG C + W F++ ++E + + +S + +C Y+GE + CDEG
Sbjct: 579 VEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANC------YKGEHKDRCDEGS 632
Query: 191 NGGLQPNAYNYIIKNGG-IQTESSYPYT-AETGTQCN----------------------- 225
+ P + II++ G + ES+YPY + G QC
Sbjct: 633 S----PMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPN 688
Query: 226 ---------FNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFD 276
+ S + F I K E + G +++ I A+ V + G
Sbjct: 689 SLDGKGYTAYESERFHDNMDAFVKIIKTEVMNKGSVIAY----IKAENVMGYEFSGKKVQ 744
Query: 277 IPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 336
C ++ DH + IVGY + YWIV+NSWG WG++GY + T N
Sbjct: 745 NLCGDDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHCHFN 804
Query: 337 FVSTSII 343
F+ + +I
Sbjct: 805 FIHSVVI 811
>sp|P32956|CC3_CARCN CYSTEINE PROTEINASE III (CC-III)
Length = 43
Score = 63.2 bits (151), Expect = 8e-10
Identities = 25/35 (71%), Positives = 28/35 (79%)
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 153
P + DWR +GAVTPVKNQG CGSCW+FST VEG
Sbjct: 2 PESIDWRKKGAVTPVKNQGSCGSCWAFSTIATVEG 36
>sp|P32957|CC4_CARCN CYSTEINE PROTEINASE IV (CC-IV)
Length = 43
Score = 62.1 bits (148), Expect = 2e-09
Identities = 25/35 (71%), Positives = 28/35 (79%)
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 153
P + DWR +GAVTPVKNQG CGSCW+FST VEG
Sbjct: 2 PESIDWRKKGAVTPVKNQGSCGSCWAFSTIVTVEG 36
>sp|Q06544|CYS3_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3
Length = 174
Score = 59.3 bits (141), Expect = 1e-08
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 15/103 (14%)
Query: 241 IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF 300
I KN V+AG+IV ++ Y G++ + H + I+G+ +
Sbjct: 87 IMKNGPVVAGFIVYE----------DFAHYKSGIYKHTAGRMTGGHAVKIIGWGKE---- 132
Query: 301 RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
K PYW++ NSW DWGE+G+ + RG N C + V I+
Sbjct: 133 -KGTPYWLIANSWHDDWGEKGFYRMIRGINNCRIEEMVFAGIV 174
>sp|P32954|CC1_CARCN CYSTEINE PROTEINASE I (CC-I)
Length = 43
Score = 58.6 bits (139), Expect = 2e-08
Identities = 23/36 (63%), Positives = 28/36 (76%)
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 153
I + DWR +GAVTPV+NQG CGSCW+FS+ VEG
Sbjct: 1 IVASIDWRQKGAVTPVRNQGSCGSCWTFSSVAAVEG 36
>sp|P32955|CC2_CARCN CYSTEINE PROTEINASE II (CC-II)
Length = 43
Score = 58.2 bits (138), Expect = 3e-08
Identities = 23/35 (65%), Positives = 27/35 (76%)
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 153
P + DWR +GAVTPVK+Q CGSCW+FST VEG
Sbjct: 2 PGSVDWRQKGAVTPVKDQNPCGSCWAFSTVATVEG 36
>sp||CATL_CHICK_2 [Segment 2 of 2] CATHEPSIN L
Length = 42
Score = 51.9 bits (122), Expect = 2e-06
Identities = 20/39 (51%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
Query: 306 YWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 343
YWIVKNSWG WG++GYIY+ + KN CG++ S ++
Sbjct: 4 YWIVKNSWGEKWGDKGYIYMAKDRKNHCGIATAASYPLV 42
>sp|P12399|CT2A_MOUSE CTLA-2-ALPHA PROTEIN PRECURSOR
Length = 136
Score = 41.8 bits (96), Expect = 0.002
Identities = 31/101 (30%), Positives = 50/101 (48%), Gaps = 4/101 (3%)
Query: 9 LAVFTVFVSSRGIPPEEQ--SQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIA 66
L + + + S PP+ +++ E++ KF K Y+ E R +++ N KIE N
Sbjct: 17 LLILCLGMMSAAPPPDPSLDNEWKEWKTKFAKAYNLNEERHRRLVWEENKKKIEAHNADY 76
Query: 67 INHKADTKFGVNKFADLSSDEFK-NYYLNN-KEAIFTDDLP 105
K G+N+F+DL+ +EFK N Y N+ DLP
Sbjct: 77 EQGKTSFYMGLNQFSDLTPEEFKTNCYGNSLNRGEMAPDLP 117
>sp|P21381|THPA_THADA THAUMATOPAIN
Length = 35
Score = 40.6 bits (93), Expect = 0.005
Identities = 16/31 (51%), Positives = 22/31 (70%)
Query: 117 SIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
++P + DW +GAV VKNQ CGSC +FS+
Sbjct: 1 NLPNSVDWWKKGAVAAVKNQRXCGSCXAFSS 31
>sp|P05689|CATX_BOVIN CATHEPSIN
Length = 73
Score = 40.2 bits (92), Expect = 0.006
Identities = 15/40 (37%), Positives = 24/40 (59%), Gaps = 5/40 (12%)
Query: 284 LDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 323
++H + + G+ + M YWIV+NSWG WGE G++
Sbjct: 9 INHIVSVAGWGVSD-----GMEYWIVRNSWGEPWGEHGWM 43
>sp|P12400|CT2B_MOUSE CTLA-2-BETA PROTEIN PRECURSOR
Length = 141
Score = 38.7 bits (88), Expect = 0.018
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 6 LFVLAVFTVFVSSRGIP-PEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNL 64
+F+L + +S+ P P +++ E++ F K YS +E R +++ N KIE N
Sbjct: 20 VFLLILCLGMMSAAPSPDPSLDNEWKEWKTTFAKAYSLDEERHRRLMWEENKKKIEAHNA 79
Query: 65 IAINHKADTKFGVNKFADLSSDEFK 89
K G+N+F+DL+ +EF+
Sbjct: 80 DYERGKTSFYMGLNQFSDLTPEEFR 104
>sp|P20736|BM86_BOOMI GLYCOPROTEIN ANTIGEN BM86 PRECURSOR (PROTECTIVE ANTIGEN)
Length = 650
Score = 35.2 bits (79), Expect = 0.21
Identities = 24/81 (29%), Positives = 36/81 (43%), Gaps = 5/81 (6%)
Query: 147 TTGNVEGQHFISQNKLVSLSEQNLVDC----DHECMEYEGEEACDEGCNGGLQPNAYNYI 202
TT N + KL + + + +C DHEC +++C E NG Q + +
Sbjct: 533 TTCNPKEIQECQDKKLECVYKNHKAECECPDDHECYREPAKDSCSEEDNGKCQSSGQRCV 592
Query: 203 IKNG-GIQTESSYPYTAETGT 222
I+NG + E S TA T T
Sbjct: 593 IENGKAVCKEKSEATTAATTT 613
>sp|Q11121|PLB1_TORDE LYSOPHOSPHOLIPASE PRECURSOR (PHOSPHOLIPASE B)
Length = 649
Score = 34.8 bits (78), Expect = 0.27
Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 13/144 (9%)
Query: 109 YLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQ 168
Y DDE + I F+ TRG +T + C +C + + K SL+
Sbjct: 519 YTDDERLKMIKNGFEAATRGNLTDDSSFMGCVAC-------------AVMRRKQQSLNAT 565
Query: 169 NLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNS 228
+C Y D+ GL + ++ + ++ Y++ + T N
Sbjct: 566 LPEECSTCFTNYCWNGTIDDTPVSGLDNSDFDPTAASSAYSAYNTESYSSSSATGSKKNG 625
Query: 229 ANIGAKISNFTMIPKNETVMAGYI 252
A + A ++FT I T +AG++
Sbjct: 626 AGLPATPTSFTSILTLLTAIAGFL 649
>sp|P46992|YJR1_YEAST HYPOTHETICAL 43.0 KD PROTEIN IN CPS1-FPP1 INTERGENIC REGION
Length = 396
Score = 33.6 bits (75), Expect = 0.61
Identities = 40/191 (20%), Positives = 76/191 (38%), Gaps = 43/191 (22%)
Query: 77 VNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEF------------------INSI 118
VNKF D++++E + ++ + P+ADYL F +N+
Sbjct: 42 VNKFKDITNNESCTCEVGDRVWFSGKNAPLADYLSVHFRGPLKLKQFAFYTSPGFTVNNS 101
Query: 119 PTAFDW----------RTRGAVTPVKNQGQCGSCW-------SFSTTGNVEGQHFISQNK 161
++ DW +T VT + + G+ C S + TG+ ++
Sbjct: 102 RSSSDWNRLAYYESSSKTADNVTFLNHGGEASPCLGNALSYASSNGTGSASEATVLADGT 161
Query: 162 LVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETG 221
L+S ++ ++ + C + ++ C +G P Y Y GG T + + E
Sbjct: 162 LISSDQEYIIYSNVSCPKSGYDKGCGVYRSG--IPAYYGY----GG--TTKMFLFEFEMP 213
Query: 222 TQCNFNSANIG 232
T+ NS++IG
Sbjct: 214 TETEKNSSSIG 224
>sp|P28493|PR5_ARATH PATHOGENESIS-RELATED PROTEIN 5 PRECURSOR (PR-5)
Length = 239
Score = 32.1 bits (71), Expect = 1.8
Identities = 24/93 (25%), Positives = 36/93 (37%), Gaps = 7/93 (7%)
Query: 133 VKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNG 192
++ G G C G V + + L + + N+V C C + ++ C G N
Sbjct: 137 IRPSGGSGDC---KYAGCVSDLNAACPDMLKVMDQNNVVACKSACERFNTDQYCCRGAND 193
Query: 193 GLQ---PNAYNYIIKNGGIQTESSYPYTAETGT 222
+ P Y+ I KN SY Y ET T
Sbjct: 194 KPETCPPTDYSRIFKN-ACPDAYSYAYDDETST 225
>sp|P41901|SPR3_YEAST SPORULATION-SPECIFIC SEPTIN
Length = 512
Score = 31.7 bits (70), Expect = 2.4
Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 9/63 (14%)
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
+ +NLI + K+D L+ +E KN+ +E I D+PV + DE +N+
Sbjct: 237 KRVNLIPVIAKSDL---------LTKEELKNFKTQVREIIRVQDIPVCFFFGDEVLNATQ 287
Query: 120 TAF 122
F
Sbjct: 288 DIF 290
>sp|P54634|POLN_LORDV NON-STRUCTURAL POLYPROTEIN [CONTAINS: RNA-DIRECTED RNA POLYMERASE ;
THIOL PROTEASE 3C ; HELICASE (2C LIKE PROTEIN)]
Length = 1699
Score = 31.3 bits (69), Expect = 3.1
Identities = 13/31 (41%), Positives = 21/31 (66%)
Query: 17 SSRGIPPEEQSQFLEFQDKFNKKYSHEEYLE 47
SS+G+ EE ++ +++ N KYS EEYL+
Sbjct: 893 SSKGLSDEEYDEYKRIREERNGKYSIEEYLQ 923
>sp|P21173|DNAA_MICLU CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA
Length = 515
Score = 31.3 bits (69), Expect = 3.1
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 13/104 (12%)
Query: 31 EFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKN 90
EF + F H+E +++++ ++ L + I AD + V +F F
Sbjct: 247 EFTNDFINSIRHDEGASFKQVYRN----VDILLIDDIQFLADKEATVEEFFHT----FNT 298
Query: 91 YYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVK 134
Y NNK+ + T DLP F + + + F+W G +T ++
Sbjct: 299 LYNNNKQVVITSDLPPKQL--SGFEDRLRSRFEW---GLITDIQ 337
>sp|P89263|Y022_GVXN HYPOTHETICAL ORF22 HOMOLOG
Length = 166
Score = 30.5 bits (67), Expect = 5.3
Identities = 27/107 (25%), Positives = 43/107 (39%), Gaps = 9/107 (8%)
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
SF T G H SQ V +S Q+LV Y+ CD+ Y+ ++
Sbjct: 66 SFDTLEGPGGGHCFSQP--VRVSRQDLVT-------YDCASLCDDVRAAYFYVGPYDRLV 116
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAG 250
+G E Y T CN ++ + I+++T I ++ AG
Sbjct: 117 VDGNELQEGGYCTTNSVPRNCNRETSILLHSINHWTCIAEDPRYYAG 163
>sp|P24896|NU5M_CAEEL NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5
Length = 527
Score = 30.5 bits (67), Expect = 5.3
Identities = 21/52 (40%), Positives = 26/52 (49%), Gaps = 7/52 (13%)
Query: 44 EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNN 95
+YL + I+K K +L L IN K T F LSS FKNYYL +
Sbjct: 466 DYLAKNSIYKMKNLKFMDLFLNNINSKGYTLF-------LSSGMFKNYYLKS 510
>sp|P25648|SRB8_YEAST SUPPRESSOR OF RNA POLYMERASE B SRB8
Length = 1427
Score = 30.1 bits (66), Expect = 7.0
Identities = 22/89 (24%), Positives = 44/89 (48%), Gaps = 10/89 (11%)
Query: 21 IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGV--- 77
+PP + S F++ + Y EE ++ E F NLG + ++ I H+ + K+ +
Sbjct: 1314 LPPFQVSSFVKETKLHSGDYGEEEDADQEESFSLNLG----IGIVEIAHENEQKWLIYDK 1369
Query: 78 --NKFADLSSDEFKNYYLNNKEAIFTDDL 104
+K+ S E ++++N +TDD+
Sbjct: 1370 KDHKYVCTFSME-PYHFISNYNTKYTDDM 1397
>sp|Q04723|PEPC_LACLC AMINOPEPTIDASE C
Length = 436
Score = 30.1 bits (66), Expect = 7.0
Identities = 11/20 (55%), Positives = 14/20 (70%)
Query: 303 NMPYWIVKNSWGADWGEQGY 322
N W V+NSWG D G++GY
Sbjct: 370 NSTKWKVENSWGKDAGQKGY 389
>sp|Q13867|BLMH_HUMAN BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH)
Length = 455
Score = 29.7 bits (65), Expect = 9.1
Identities = 10/17 (58%), Positives = 13/17 (75%)
Query: 307 WIVKNSWGADWGEQGYI 323
W V+NSWG D G +GY+
Sbjct: 392 WRVENSWGEDHGHKGYL 408
>sp|P87362|BLMH_CHICK BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) (AMINOPEPTIDASE H)
Length = 455
Score = 29.7 bits (65), Expect = 9.1
Identities = 10/19 (52%), Positives = 14/19 (73%)
Query: 307 WIVKNSWGADWGEQGYIYL 325
W V+NSWG D G +GY+ +
Sbjct: 392 WRVENSWGEDRGNKGYLIM 410
>sp|P70645|BLMH_RAT BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH)
Length = 454
Score = 29.7 bits (65), Expect = 9.1
Identities = 10/17 (58%), Positives = 13/17 (75%)
Query: 307 WIVKNSWGADWGEQGYI 323
W V+NSWG D G +GY+
Sbjct: 392 WRVENSWGEDHGHKGYL 408
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
sp|P04988|CYS1_DICDI CYSTEINE PROTEINASE 1 PRECURSOR 527 e-149
sp|P25975|CATL_BOVIN CATHEPSIN L PRECURSOR 440 e-123
sp|P07154|CATL_RAT CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN... 431 e-121
sp|P06797|CATL_MOUSE CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTE... 431 e-120
sp|Q28944|CATL_PIG CATHEPSIN L PRECURSOR 430 e-120
sp|P07711|CATL_HUMAN CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTE... 421 e-118
sp|O60911|CATM_HUMAN CATHEPSIN L2 PRECURSOR (CATHEPSIN V) 417 e-116
sp|P43296|RD19_ARATH CYSTEINE PROTEINASE RD19A PRECURSOR 412 e-115
sp|P25776|ORYA_ORYSA ORYZAIN ALPHA CHAIN PRECURSOR 407 e-113
sp|P25782|CYS2_HOMAM DIGESTIVE CYSTEINE PROTEINASE 2 PRECURSOR 403 e-112
sp|P43295|A494_ARATH PROBABLE CYSTEINE PROTEINASE A494 PRECURSOR 402 e-112
sp|P43235|CATK_HUMAN CATHEPSIN K PRECURSOR (CATHEPSIN O) (CATHEP... 401 e-111
sp|P25804|CYSP_PEA CYSTEINE PROTEINASE 15A PRECURSOR (TURGOR-RES... 399 e-111
sp|P04989|CYS2_DICDI CYSTEINE PROTEINASE 2 PRECURSOR (PRESTALK C... 398 e-111
sp|P43236|CATK_RABIT CATHEPSIN K PRECURSOR (OC-2 PROTEIN) 395 e-110
sp|P54640|CYS5_DICDI CYSTEINE PROTEINASE 5 PRECURSOR 394 e-109
sp|P13277|CYS1_HOMAM DIGESTIVE CYSTEINE PROTEINASE 1 PRECURSOR 393 e-109
sp|P25784|CYS3_HOMAM DIGESTIVE CYSTEINE PROTEINASE 3 PRECURSOR 392 e-109
sp|P25774|CATS_HUMAN CATHEPSIN S PRECURSOR 392 e-109
sp|P15242|TES1_RAT TESTIN 1/2 PRECURSOR (CMB-22/CMB-23) 391 e-109
sp|Q10716|CYS1_MAIZE CYSTEINE PROTEINASE 1 PRECURSOR 391 e-108
sp|P12412|CYSP_VIGMU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYS... 389 e-108
sp|P43297|RD21_ARATH CYSTEINE PROTEINASE RD21A PRECURSOR 387 e-107
sp|P55097|CATK_MOUSE CATHEPSIN K PRECURSOR 384 e-106
sp|P09668|CATH_HUMAN CATHEPSIN H PRECURSOR 383 e-106
sp|O46427|CATH_PIG CATHEPSIN H PRECURSOR 382 e-106
sp|P25803|CYSP_PHAVU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYS... 380 e-105
sp|P00786|CATH_RAT CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPS... 377 e-104
sp|P25251|CYS4_BRANA CYSTEINE PROTEINASE COT44 PRECURSOR 376 e-104
sp|P05167|ALEU_HORVU THIOL PROTEASE ALEURAIN PRECURSOR 375 e-104
sp|Q10717|CYS2_MAIZE CYSTEINE PROTEINASE 2 PRECURSOR 374 e-103
sp|P25777|ORYB_ORYSA ORYZAIN BETA CHAIN PRECURSOR 374 e-103
sp|Q40143|CYS3_LYCES CYSTEINE PROTEINASE 3 PRECURSOR 373 e-103
sp|P43156|CYSP_HEMSP THIOL PROTEASE SEN102 PRECURSOR 373 e-103
sp|P49935|CATH_MOUSE CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHE... 372 e-103
sp|P25778|ORYC_ORYSA ORYZAIN GAMMA CHAIN PRECURSOR 370 e-102
sp|P00785|ACTN_ACTCH ACTINIDAIN PRECURSOR (ACTINIDIN) 368 e-102
sp|P41721|CATV_NPVBM VIRAL CATHEPSIN (V-CATH) 367 e-101
sp|Q02765|CATS_RAT CATHEPSIN S PRECURSOR 365 e-100
sp|P14658|CYSP_TRYBB CYSTEINE PROTEINASE PRECURSOR 365 e-100
sp|P25783|CATV_NPVAC VIRAL CATHEPSIN (V-CATH) 363 e-100
sp|P41715|CATV_NPVCF VIRAL CATHEPSIN (V-CATH) 363 e-100
sp|P25250|CYS2_HORVU CYSTEINE PROTEINASE EP-B 2 PRECURSOR 361 e-100
sp|P25249|CYS1_HORVU CYSTEINE PROTEINASE EP-B 1 PRECURSOR 361 1e-99
sp|Q26534|CATL_SCHMA CATHEPSIN L PRECURSOR (SMCL1) 361 2e-99
sp|P25779|CYSP_TRYCR CRUZIPAIN PRECURSOR (MAJOR CYSTEINE PROTEIN... 356 4e-98
sp|O10364|CATV_NPVOP VIRAL CATHEPSIN (V-CATH) 351 2e-96
sp|P36400|LCPB_LEIME CYSTEINE PROTEINASE B PRECURSOR 348 1e-95
sp|P25775|LCPA_LEIME CYSTEINE PROTEINASE A PRECURSOR 348 1e-95
sp|Q05094|CYS2_LEIPI CYSTEINE PROTEINASE 2 PRECURSOR (AMASTIGOTE... 347 2e-95
sp|P35591|CYS1_LEIPI CYSTEINE PROTEINASE 1 PRECURSOR (AMASTIGOTE... 347 3e-95
sp|P05994|PAP4_CARPA PAPAYA PROTEINASE IV PRECURSOR (PPIV) (PAPA... 346 3e-95
sp|P10056|PAP3_CARPA CARICAIN PRECURSOR (PAPAYA PROTEINASE OMEGA... 341 1e-93
sp|P14080|PAP2_CARPA CHYMOPAPAIN PRECURSOR (PAPAYA PROTEINASE II... 339 6e-93
sp|P00784|PAPA_CARPA PAPAIN PRECURSOR (PAPAYA PROTEINASE I) (PPI) 334 1e-91
sp|P22895|P34_SOYBN P34 PROBABLE THIOL PROTEASE PRECURSOR 331 1e-90
sp|O17473|CATL_BRUPA CATHEPSIN L-LIKE PRECURSOR 327 2e-89
sp|Q10991|CATL_SHEEP CATHEPSIN L 325 1e-88
sp|P54639|CYS4_DICDI CYSTEINE PROTEINASE 4 PRECURSOR 323 4e-88
sp|P56203|CATW_MOUSE CATHEPSIN W PRECURSOR (LYMPHOPAIN) 319 4e-87
sp|P56202|CATW_HUMAN CATHEPSIN W PRECURSOR (LYMPHOPAIN) 318 9e-87
sp|Q01958|CPP2_ENTHI CYSTEINE PROTEINASE 2 PRECURSOR 318 9e-87
sp|P36185|ACP2_ENTHI CYSTEINE PROTEINASE ACP2 PRECURSOR 315 8e-86
sp|Q06964|CPP3_ENTHI CYSTEINE PROTEINASE 3 PRECURSOR (CYSTEINE P... 312 9e-85
sp|P36184|ACP1_ENTHI CYSTEINE PROTEINASE ACP1 PRECURSOR 309 5e-84
sp|P25326|CATS_BOVIN CATHEPSIN S 307 2e-83
sp|Q01957|CPP1_ENTHI CYSTEINE PROTEINASE 1 PRECURSOR 301 1e-81
sp|P25805|CYSP_PLAFA THROPHOZOITE CYSTEINE PROTEINASE PRECURSOR ... 299 5e-81
sp|P20721|CYSL_LYCES LOW-TEMPERATURE-INDUCED CYSTEINE PROTEINASE... 298 9e-81
sp|P43234|CATO_HUMAN CATHEPSIN O PRECURSOR 296 5e-80
sp|P46102|CYSP_PLAVN CYSTEINE PROTEINASE PRECURSOR 291 1e-78
sp|P42666|CYSP_PLAVI CYSTEINE PROTEINASE PRECURSOR 278 1e-74
sp|P16311|MMAL_DERFA MAJOR MITE FECAL ALLERGEN DER F 1 PRECURSOR... 272 8e-73
sp|P80884|ANAN_ANACO ANANAIN 271 1e-72
sp||CATL_CHICK_1 [Segment 1 of 2] CATHEPSIN L 264 1e-70
sp|P97821|CATC_MOUSE DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (D... 262 9e-70
sp|P25781|CYSP_THEAN CYSTEINE PROTEINASE PRECURSOR 259 6e-69
sp|P08176|MMAL_DERPT MAJOR MITE FECAL ALLERGEN DER P 1 PRECURSOR... 255 1e-67
sp|P14518|BROM_ANACO BROMELAIN, STEM 253 4e-67
sp|P53634|CATC_HUMAN DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (D... 251 2e-66
sp|P80067|CATC_RAT DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPP... 250 4e-66
sp|P22497|CYSP_THEPA CYSTEINE PROTEINASE PRECURSOR 243 5e-64
sp|P07858|CATB_HUMAN CATHEPSIN B PRECURSOR (CATHEPSIN B1) (APP S... 238 1e-62
sp|P00787|CATB_RAT CATHEPSIN B PRECURSOR (CATHEPSIN B1) (RSG-2) 236 4e-62
sp|P10605|CATB_MOUSE CATHEPSIN B PRECURSOR (CATHEPSIN B1) 233 4e-61
sp|P43509|CPR5_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 5 PREC... 232 8e-61
sp|P07688|CATB_BOVIN CATHEPSIN B PRECURSOR 232 8e-61
sp|P43233|CATB_CHICK CATHEPSIN B PRECURSOR (CATHEPSIN B1) 232 1e-60
sp|Q26563|CATC_SCHMA CATHEPSIN C PRECURSOR 231 1e-60
sp|P25807|CYS1_CAEEL GUT-SPECIFIC CYSTEINE PROTEINASE PRECURSOR 231 1e-60
sp|P43508|CPR4_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 4 PREC... 231 2e-60
sp|P43510|CPR6_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6 PREC... 225 8e-59
sp|P43157|CYSP_SCHJA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECUR... 222 1e-57
sp|P25792|CYSP_SCHMA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECUR... 216 5e-56
sp|P25802|CYS1_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PREC... 213 4e-55
sp|P25793|CYS2_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 2 PREC... 212 1e-54
sp|P19092|CYS1_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PREC... 208 2e-53
sp|P43507|CPR3_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3 PREC... 204 3e-52
sp|P25780|EUM1_EURMA MITE GROUP I ALLERGEN EUR M 1 (EUR M I) 201 1e-51
sp|P25773|CATL_FELCA CATHEPSIN L (PROGESTERONE-DEPENDENT PROTEIN... 185 2e-46
sp|Q23894|CYS3_DICDI CYSTEINE PROTEINASE 3 (CYSTEINE PROTEINASE II) 158 2e-38
sp|P13823|SERA_PLAFG SERINE-REPEAT ANTIGEN PROTEIN PRECURSOR (P1... 157 3e-38
sp|Q06544|CYS3_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3 139 6e-33
sp|P05993|PAP5_CARPA CYSTEINE PROTEINASE (CLONE PLBPC13) 131 2e-30
sp|P32957|CC4_CARCN CYSTEINE PROTEINASE IV (CC-IV) 85 3e-16
sp|P32956|CC3_CARCN CYSTEINE PROTEINASE III (CC-III) 84 4e-16
sp|P32955|CC2_CARCN CYSTEINE PROTEINASE II (CC-II) 81 2e-15
sp||CATL_CHICK_2 [Segment 2 of 2] CATHEPSIN L 77 5e-14
sp|P32954|CC1_CARCN CYSTEINE PROTEINASE I (CC-I) 76 1e-13
Sequences not found previously or not previously below threshold:
sp|P12399|CT2A_MOUSE CTLA-2-ALPHA PROTEIN PRECURSOR 98 2e-20
sp|P12400|CT2B_MOUSE CTLA-2-BETA PROTEIN PRECURSOR 96 1e-19
sp|P05689|CATX_BOVIN CATHEPSIN 60 9e-09
sp|P94869|PEPG_LACDL AMINOPEPTIDASE G 46 1e-04
sp|P94870|PEPE_LACHE AMINOPEPTIDASE E 43 0.001
sp|P94868|PEPW_LACDL AMINOPEPTIDASE W 42 0.002
sp|Q10744|PEPC_LACHE AMINOPEPTIDASE C 41 0.003
sp|Q04723|PEPC_LACLC AMINOPEPTIDASE C 40 0.009
sp|Q48543|PEPC_LACDL AMINOPEPTIDASE C 38 0.025
sp|P21381|THPA_THADA THAUMATOPAIN 38 0.025
sp|Q56115|PEPC_STRTR AMINOPEPTIDASE C 36 0.13
sp|P09983|HLY1_ECOLI HEMOLYSIN, CHROMOSOMAL 36 0.17
sp|P33403|CYSP_TRIFO CYSTEINE PROTEINASE 35 0.28
sp|P08715|HLYA_ECOLI HEMOLYSIN, PLASMID 35 0.28
sp|P87362|BLMH_CHICK BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) (... 34 0.37
sp|P54704|PSPB_DICDI PRESPORE PROTEIN B PRECURSOR 34 0.37
sp|Q13867|BLMH_HUMAN BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) 34 0.49
sp|P70645|BLMH_RAT BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) 34 0.49
sp|P80532|CAT3_FASHE PUTATIVE CATHEPSIN L3 (NEWLY EXCYSTED JUVEN... 34 0.49
sp|P16462|LKTA_ACTAC LEUKOTOXIN 34 0.49
sp|P13438|TSP_MOUSE TROPHOBLAST-SPECIFIC PROTEIN PRECURSOR 32 1.4
sp|Q00951|HLYA_ACTSU HEMOLYSIN (CYTOLYSIN II) (CLY-IIA) (HLY-IIA... 32 1.4
sp|P15377|RT2A_ACTPL RTX-II TOXIN DETERMINANT A (APX-IIA) (HEMOL... 32 1.4
sp|P52181|TGLC_PAGMA PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE... 32 1.9
sp|P35681|TCTP_ORYSA TRANSLATIONALLY CONTROLLED TUMOR PROTEIN HO... 32 1.9
sp|Q01532|BLH1_YEAST CYSTEINE PROTEINASE 1 (Y3) (BLEOMYCIN HYDRO... 32 2.5
sp|P16312|MMAL_DERMI MAJOR MITE FECAL ALLERGEN DER M 1 (DER M I) 31 3.2
sp|O03992|TCTP_FRAAN TRANSLATIONALLY CONTROLLED TUMOR PROTEIN HO... 31 4.2
sp|Q04489|YMJ6_YEAST HYPOTHETICAL 59.5 KD PROTEIN IN VPS9-RAD10 ... 31 4.2
sp|Q03164|HRX_HUMAN ZINC FINGER PROTEIN HRX (ALL-1) (TRITHORAX-L... 31 4.2
sp||CATB_COTJA_1 [Segment 1 of 2] CATHEPSIN B (CATHEPSIN B1) 30 5.6
sp|Q62703|RCN2_RAT RETICULOCALBIN 2 PRECURSOR (CALCIUM-BINDING P... 30 5.6
sp|P48651|PSS1_HUMAN PHOSPHATIDYLSERINE SYNTHASE I (SERINE-EXCHA... 30 5.6
sp|P33404|CYSP_TRIVA CYSTEINE PROTEINASE 30 5.6
sp|Q00576|PSS1_CRILO PHOSPHATIDYLSERINE SYNTHASE I (SERINE-EXCHA... 30 5.6
sp|Q9ZRX0|TCTP_PSEMZ TRANSLATIONALLY CONTROLLED TUMOR PROTEIN HO... 30 7.3
sp|Q94480|V136_DICDI VEG136 PROTEIN 30 7.3
sp|P55131|RT32_ACTPL RTX-III TOXIN DETERMINANT A FROM SEROTYPE 8... 30 7.3
sp|P55130|RT31_ACTPL RTX-III TOXIN DETERMINANT A FROM SEROTYPE 2... 30 7.3
sp|P40101|YE16_YEAST HYPOTHETICAL 35.9 KD PROTEIN IN ISC10 3'REGION 30 7.3
sp|P13388|XMRK_XIPMA MELANOMA RECEPTOR PROTEIN-TYROSINE KINASE P... 30 7.3
sp|Q9ZL75|MOAA_HELPJ MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A 30 9.5
sp|P55129|RT12_ACTPL RTX-I TOXIN DETERMINANT A FROM SEROTYPES 5/... 30 9.5
sp|P55128|RT11_ACTPL RTX-I TOXIN DETERMINANT A FROM SEROTYPES 1/... 30 9.5
sp|P35669|GSHB_SCHPO GLUTATHIONE SYNTHETASE LARGE CHAIN (GLUTATH... 30 9.5
sp|P11140|ABRA_ABRPR ABRIN-A PRECURSOR (RRNA N-GLYCOSIDASE) 30 9.5
sp|Q00690|LEM2_MOUSE E-SELECTIN PRECURSOR (ENDOTHELIAL LEUKOCYTE... 30 9.5
sp|P06620|ICEN_PSESY ICE NUCLEATION PROTEIN 30 9.5
>sp|P04988|CYS1_DICDI CYSTEINE PROTEINASE 1 PRECURSOR
Length = 343
Score = 527 bits (1343), Expect = e-149
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE
Sbjct: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPT 120
ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPT
Sbjct: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPT 120
Query: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY
Sbjct: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
Query: 181 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM 240
EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM
Sbjct: 181 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM 240
Query: 241 IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF 300
IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF
Sbjct: 241 IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF 300
Query: 301 RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII
Sbjct: 301 RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
>sp|P25975|CATL_BOVIN CATHEPSIN L PRECURSOR
Length = 334
Score = 440 bits (1119), Expect = e-123
Identities = 120/343 (34%), Positives = 176/343 (50%), Gaps = 19/343 (5%)
Query: 7 FVLAVFTVFVSSRG--IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNL 64
F L V + V+S + P + + +++ + Y E R +++ N I+ N
Sbjct: 5 FFLTVLCLGVASAAPKLDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQ 64
Query: 65 IAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDW 124
K + +N F D++++EF+ + + +P + DW
Sbjct: 65 EYSEGKHAFRMAMNAFGDMTNEEFRQVMNG----FQNQKHKKGKLFHEPLLVDVPKSVDW 120
Query: 125 RTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEE 184
+G VTPVKNQGQCGSCW+FS TG +EGQ F KLVSLSEQNLVDC
Sbjct: 121 TKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRA-------- 172
Query: 185 ACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN 244
++GCNGGL NA+ YI NGG+ +E SYPY A CN+ A + F IP+
Sbjct: 173 QGNQGCNGGLMDNAFQYIKDNGGLDSEESYPYLATDTNSCNYKPECSAANDTGFVDIPQR 232
Query: 245 ETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFR 301
E + + + GP+++A DA +QFY G+ +D C+ LDHG+L+VGY + T
Sbjct: 233 EKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSN 292
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 343
N +WIVKNSWG +WG GY+ + + N CG++ S +
Sbjct: 293 NNK-FWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|P07154|CATL_RAT CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP) (CYCLIC
PROTEIN-2) (CP-2)
Length = 334
Score = 431 bits (1097), Expect = e-121
Identities = 123/345 (35%), Positives = 187/345 (53%), Gaps = 19/345 (5%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEEL 62
++LL VL + T + + +Q+ +++ + Y E R +++ N+ I+
Sbjct: 4 LLLLAVLCLGTALATPKF-DQTFNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQLH 62
Query: 63 NLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAF 122
N N K +N F D++++EF+ + + + IP
Sbjct: 63 NGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKH----KKGRLFQEPLMLQIPKTV 118
Query: 123 DWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEG 182
DWR +G VTPVKNQGQCGSCW+FS +G +EGQ F+ KL+SLSEQNLVDC H
Sbjct: 119 DWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSH------- 171
Query: 183 EEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP 242
+ ++GCNGGL A+ YI +NGG+ +E SYPY A+ G C + + A + F IP
Sbjct: 172 -DQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDG-SCKYRAEYAVANDTGFVDIP 229
Query: 243 KNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGYSAKNTI 299
+ E + + + GP+++A DA QFY G++ P C+ LDHG+L+VGY + T
Sbjct: 230 QQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTD 289
Query: 300 FRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 343
K+ YW+VKNSWG +WG GYI + + + N CG++ S I+
Sbjct: 290 SNKDK-YWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333
>sp|P06797|CATL_MOUSE CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP)
Length = 334
Score = 431 bits (1096), Expect = e-120
Identities = 120/347 (34%), Positives = 189/347 (53%), Gaps = 18/347 (5%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
M ++LL + +++ +++ +++ + Y E R I++ N+ I+
Sbjct: 1 MNLLLLLAVLCLGTALATPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQ 60
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPT 120
N N + +N F D++++EF+ + + + IP
Sbjct: 61 LHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKH----KKGRLFQEPLMLKIPK 116
Query: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
+ DWR +G VTPVKNQGQCGSCW+FS +G +EGQ F+ KL+SLSEQNLVDC H
Sbjct: 117 SVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHA---- 172
Query: 181 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM 240
++GCNGGL A+ YI +NGG+ +E SYPY A+ G C + + A + F
Sbjct: 173 ----QGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDG-SCKYRAEFAVANDTGFVD 227
Query: 241 IPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGYSAKN 297
IP+ E + + + GP+++A DA QFY G++ P C+ +LDHG+L+VGY +
Sbjct: 228 IPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEG 287
Query: 298 TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 343
T KN YW+VKNSWG++WG +GYI + + + N CG++ S ++
Sbjct: 288 TDSNKNK-YWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333
>sp|Q28944|CATL_PIG CATHEPSIN L PRECURSOR
Length = 334
Score = 430 bits (1094), Expect = e-120
Identities = 115/343 (33%), Positives = 171/343 (49%), Gaps = 19/343 (5%)
Query: 7 FVLAVFTVFVSSRG--IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNL 64
L + ++S + + + +++ + Y E R +++ N+ IE N
Sbjct: 5 LFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQ 64
Query: 65 IAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDW 124
K +N F D++++EF+ + + +P + DW
Sbjct: 65 EYSQGKHGFSMAMNAFGDMTNEEFRQVMNG----FQNQKHKKGKVFHESLVLEVPKSVDW 120
Query: 125 RTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEE 184
R +G VT VKNQGQCGSCW+FS TG +EGQ F KLVSLSEQNLVDC
Sbjct: 121 REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCS--------RP 172
Query: 185 ACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN 244
++GCNGGL NA+ Y+ NGG+ TE SYPY C + A + F IP+
Sbjct: 173 QGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQR 232
Query: 245 ETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFR 301
E + + + GP+++A DA +QFY G+ +D C+ LDHG+L+VGY + T
Sbjct: 233 EKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSN 292
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 343
+ +WIVKNSWG +WG GY+ + + N CG+S S +
Sbjct: 293 SSK-FWIVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P07711|CATL_HUMAN CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP)
Length = 333
Score = 421 bits (1072), Expect = e-118
Identities = 118/343 (34%), Positives = 180/343 (52%), Gaps = 20/343 (5%)
Query: 7 FVLAVFTVFVSSRGIPPE--EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNL 64
+LA F + ++S + + ++Q+ +++ N+ Y E R +++ N+ IE N
Sbjct: 5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQ 64
Query: 65 IAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDW 124
K +N F D++S+EF+ + P + DW
Sbjct: 65 EYREGKHSFTMAMNAFGDMTSEEFRQVMNG----FQNRKPRKGKVFQEPLFYEAPRSVDW 120
Query: 125 RTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEE 184
R +G VTPVKNQGQCGSCW+FS TG +EGQ F +L+SLSEQNLVDC
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCS--------GP 172
Query: 185 ACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN 244
+EGCNGGL A+ Y+ NGG+ +E SYPY A C +N A + F IPK
Sbjct: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATE-ESCKYNPKYSVANDTGFVDIPKQ 231
Query: 245 ETVMAGYIVSTGPLAIAADA--VEWQFYIGGVF-DIPCNPNSLDHGILIVGYSAKNTIFR 301
E + + + GP+++A DA + FY G++ + C+ +DHG+L+VGY ++T
Sbjct: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 343
N YW+VKNSWG +WG GY+ + + +N CG+++ S +
Sbjct: 292 NNK-YWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>sp|O60911|CATM_HUMAN CATHEPSIN L2 PRECURSOR (CATHEPSIN V)
Length = 334
Score = 417 bits (1061), Expect = e-116
Identities = 118/346 (34%), Positives = 179/346 (51%), Gaps = 21/346 (6%)
Query: 5 LLFVLAVFTVFVSSRGI--PPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEEL 62
L VLA F + ++S +++ +++ + Y E R +++ N+ IE
Sbjct: 3 LSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELH 62
Query: 63 NLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAF 122
N K +N F D++++EF+ + F + +P +
Sbjct: 63 NGEYSQGKHGFTMAMNAFPDMTNEEFRQMMGCFRNQKFR----KGKVFREPLFLDLPKSV 118
Query: 123 DWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEG 182
DWR +G VTPVKNQ QCGSCW+FS TG +EGQ F KLVSLSEQNLVDC
Sbjct: 119 DWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCS-------- 170
Query: 183 EEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMI- 241
++GCNGG A+ Y+ +NGG+ +E SYPY A C + N A + FT++
Sbjct: 171 RPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVD-EICKYRPENSVANDTGFTVVA 229
Query: 242 PKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVF-DIPCNPNSLDHGILIVGYSAKNT 298
P E + + + GP+++A DA +QFY G++ + C+ +LDHG+L+VGY +
Sbjct: 230 PGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFE-G 288
Query: 299 IFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 343
N YW+VKNSWG +WG GY+ + + K N CG++ S +
Sbjct: 289 ANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|P43296|RD19_ARATH CYSTEINE PROTEINASE RD19A PRECURSOR
Length = 368
Score = 412 bits (1048), Expect = e-115
Identities = 148/356 (41%), Positives = 199/356 (55%), Gaps = 28/356 (7%)
Query: 6 LFVLAVFTVFVSSRGIP------------------PEEQSQFLEFQDKFNKKY-SHEEYL 46
+FVL+ F V VSS + + F F+ KF K Y S+EE+
Sbjct: 10 VFVLSFFIVSVSSSDVNDGDDLVIRQVVGGAEPQVLTSEDHFSLFKRKFGKVYASNEEHD 69
Query: 47 ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPV 106
RF +FK+NL + + GV +F+DL+ EF+ +L +
Sbjct: 70 YRFSVFKANLRRARRHQKLDP----SATHGVTQFSDLTRSEFRKKHLGVRSGFKLP--KD 123
Query: 107 ADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLS 166
A+ ++P FDWR GAVTPVKNQG CGSCWSFS TG +EG +F++ KLVSLS
Sbjct: 124 ANKAPILPTENLPEDFDWRDHGAVTPVKNQGSCGSCWSFSATGALEGANFLATGKLVSLS 183
Query: 167 EQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNF 226
EQ LVDCDHEC + E ++CD GCNGGL +A+ Y +K GG+ E YPYT + G C
Sbjct: 184 EQQLVDCDHEC-DPEEADSCDSGCNGGLMNSAFEYTLKTGGLMKEEDYPYTGKDGKTCKL 242
Query: 227 NSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDH 286
+ + I A +SNF++I +E +A +V GPLA+A +A Q YIGGV L+H
Sbjct: 243 DKSKIVASVSNFSVISIDEEQIAANLVKNGPLAVAINAGYMQTYIGGVSCPYICTRRLNH 302
Query: 287 GILIVGYSAKN--TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVST 340
G+L+VGY A K PYWI+KNSWG WGE G+ + +G+N CGV + VST
Sbjct: 303 GVLLVGYGAAGYAPARFKEKPYWIIKNSWGETWGENGFYKICKGRNICGVDSMVST 358
>sp|P25776|ORYA_ORYSA ORYZAIN ALPHA CHAIN PRECURSOR
Length = 458
Score = 407 bits (1036), Expect = e-113
Identities = 121/350 (34%), Positives = 183/350 (51%), Gaps = 27/350 (7%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQSQ--FLEFQDKFNKKYSHE-EYLERFEIFKSNLGKI 59
++LL LA + + S G EE+++ + E++ + K Y+ E R+ F+ NL I
Sbjct: 12 LLLLLSLAAADMSIVSYGERSEEEARRLYAEWKAEHGKSYNAVGEEERRYAAFRDNLRYI 71
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
+E N A + G+N+FADL+++E+++ YL + + V+D ++P
Sbjct: 72 DEHNAAADAGVHSFRLGLNRFADLTNEEYRDTYLGLRNKPRRER-KVSDRYLAADNEALP 130
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
+ DWRT+GAV +K+QG CGSCW+FS VE + I L+SLSEQ LVDCD
Sbjct: 131 ESVDWRTKGAVAEIKDQGGCGSCWAFSAIAAVEDINQIVTGDLISLSEQELVDCD----- 185
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANI-GAKISNF 238
+ +EGCNGGL A+++II NGGI TE YPY + +C+ N N I ++
Sbjct: 186 ----TSYNEGCNGGLMDYAFDFIINNGGIDTEDDYPYKGKD-ERCDVNRKNAKVVTIDSY 240
Query: 239 TMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAK 296
+ N V P+++A +A +Q Y G+F C +LDHG+ VGY +
Sbjct: 241 EDVTPNSETSLQKAVRNQPVSVAIEAGGRAFQLYSSGIFTGKCG-TALDHGVAAVGYGTE 299
Query: 297 NTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVSNFVSTSI 342
N YWIV+NSWG WGE GY+ + R CG++ S +
Sbjct: 300 N-----GKDYWIVRNSWGKSWGESGYVRMERNIKASSGKCGIAVEPSYPL 344
>sp|P25782|CYS2_HOMAM DIGESTIVE CYSTEINE PROTEINASE 2 PRECURSOR
Length = 323
Score = 403 bits (1024), Expect = e-112
Identities = 132/349 (37%), Positives = 187/349 (52%), Gaps = 32/349 (9%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKI 59
MKV +LF+ V S + F+ K+ ++Y EE R IF+ N I
Sbjct: 1 MKVAVLFLCGVALAAASPS---------WEHFKGKYGRQYVDAEEDSYRRVIFEQNQKYI 51
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
EE N N + +NKF D++ +EF N I PV+ + +
Sbjct: 52 EEFNKKYENGEVTFNLAMNKFGDMTLEEFNAVMKGN---IPRRSAPVSVFYPKKETGPQA 108
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
T DWRT+GAVTPVK+QGQCGSCW+FSTTG++EGQHF+ L+SL+EQ LVDC
Sbjct: 109 TEVDWRTKGAVTPVKDQGQCGSCWAFSTTGSLEGQHFLKTGSLISLAEQQLVDCS----- 163
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
+GCNGG +A++YI N GI TE++YPY A G C F+S ++ A S T
Sbjct: 164 ---RPYGPQGCNGGWMNDAFDYIKANNGIDTEAAYPYEARDG-SCRFDSNSVAATCSGHT 219
Query: 240 MI-PKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGILIVGYSA 295
I +ET + + GP+++ DA +QFY GV+ P C+P+ LDH +L VGY +
Sbjct: 220 NIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGS 279
Query: 296 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 343
+ +W+VKNSW WG+ GYI + R + N CG++ S ++
Sbjct: 280 EG-----GQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323
>sp|P43295|A494_ARATH PROBABLE CYSTEINE PROTEINASE A494 PRECURSOR
Length = 313
Score = 402 bits (1021), Expect = e-112
Identities = 141/312 (45%), Positives = 187/312 (59%), Gaps = 10/312 (3%)
Query: 32 FQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKN 90
F+ KF K Y EE+ RF +FK+NL + + + + GV +F+DL+ EF+
Sbjct: 3 FKKKFGKVYGSIEEHYYRFSVFKANLLRAMRHQKMDPSARH----GVTQFSDLTRSEFRR 58
Query: 91 YYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGN 150
+L K A+ ++P FDWR RGAVTPVKNQG CGSCWSFSTTG
Sbjct: 59 KHLGVKGGFKLP--KDANQAPILPTQNLPEEFDWRDRGAVTPVKNQGSCGSCWSFSTTGA 116
Query: 151 VEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQT 210
+EG HF++ KLVSLSEQ LVDCDHEC + E E +CD GCNGGL +A+ Y +K GG+
Sbjct: 117 LEGAHFLATGKLVSLSEQQLVDCDHEC-DPEEEGSCDSGCNGGLMNSAFEYTLKTGGLMR 175
Query: 211 ESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFY 270
E YPYT G C + + I A +SNF+++ NE +A ++ GPLA+A +A Q Y
Sbjct: 176 EKDYPYTGTDGGSCKLDRSKIVASVSNFSVVSINEDQIAANLIKNGPLAVAINAAYMQTY 235
Query: 271 IGGVFDIPCNPNSLDHGILIVGYSAKN--TIFRKNMPYWIVKNSWGADWGEQGYIYLRRG 328
IGGV L+HG+L+VGY + K PYWI+KNSWG WGE G+ + +G
Sbjct: 236 IGGVSCPYICSRRLNHGVLLVGYGSAGFSQARLKEKPYWIIKNSWGESWGENGFYKICKG 295
Query: 329 KNTCGVSNFVST 340
+N CGV + VST
Sbjct: 296 RNICGVDSLVST 307
>sp|P43235|CATK_HUMAN CATHEPSIN K PRECURSOR (CATHEPSIN O) (CATHEPSIN X) (CATHEPSIN O2)
Length = 329
Score = 401 bits (1020), Expect = e-111
Identities = 121/341 (35%), Positives = 179/341 (52%), Gaps = 25/341 (7%)
Query: 9 LAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
L V + V S + PEE + + ++ K+Y+++ + + R I++ NL I NL
Sbjct: 4 LKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLE 63
Query: 66 AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWR 125
A + +N D++S+E K + Y+ E+ P + D+R
Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIP-EWEGRAPDSVDYR 122
Query: 126 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEA 185
+G VTPVKNQGQCGSCW+FS+ G +EGQ KL++LS QNLVDC E
Sbjct: 123 KKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--------- 173
Query: 186 CDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP-KN 244
++GC GG NA+ Y+ KN GI +E +YPY + C +N AK + IP N
Sbjct: 174 -NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQE-ESCMYNPTGKAAKCRGYREIPEGN 231
Query: 245 ETVMAGYIVSTGPLAIAADAV--EWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFR 301
E + + GP+++A DA +QFY GV +D CN ++L+H +L VGY +
Sbjct: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYG-----IQ 286
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVSTS 341
K +WI+KNSWG +WG +GYI + R KN CG++N S
Sbjct: 287 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFP 327
>sp|P25804|CYSP_PEA CYSTEINE PROTEINASE 15A PRECURSOR (TURGOR-RESPONSIVE PROTEIN 15A)
Length = 363
Score = 399 bits (1015), Expect = e-111
Identities = 141/322 (43%), Positives = 196/322 (60%), Gaps = 12/322 (3%)
Query: 23 PEEQSQFLEFQDKFNKKYSHEEYL-ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFA 81
+ F F+ KF+K Y+ +E RF +FKSNL K + N + G+ KF+
Sbjct: 42 LNAEHHFTSFKSKFSKSYATKEEHDYRFGVFKSNLIKAKLHQ----NRDPTAEHGITKFS 97
Query: 82 DLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGS 141
DL++ EF+ +L K+ + A ++P FDWR +GAVTPVK+QG CGS
Sbjct: 98 DLTASEFRRQFLGLKKRLRLPAH--AQKAPILPTTNLPEDFDWREKGAVTPVKDQGSCGS 155
Query: 142 CWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNY 201
CW+FSTTG +EG H+++ KLVSLSEQ LVDCDH C + E +CD GCNGGL NA+ Y
Sbjct: 156 CWAFSTTGALEGAHYLATGKLVSLSEQQLVDCDHVC-DPEQAGSCDSGCNGGLMNNAFEY 214
Query: 202 IIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIA 261
++++GG+ E Y YT G C F+ + + A +SNF+++ +E +A +V GPLA+A
Sbjct: 215 LLESGGVVQEKDYAYTGRDG-SCKFDKSKVVASVSNFSVVTLDEDQIAANLVKNGPLAVA 273
Query: 262 ADAVEWQFYIGGVFD-IPCNPNSLDHGILIVGY--SAKNTIFRKNMPYWIVKNSWGADWG 318
+A Q Y+ GV C + LDHG+L+VG+ A I K PYWI+KNSWG +WG
Sbjct: 274 INAAWMQTYMSGVSCPYVCAKSRLDHGVLLVGFGKGAYAPIRLKEKPYWIIKNSWGQNWG 333
Query: 319 EQGYIYLRRGKNTCGVSNFVST 340
EQGY + RG+N CGV + VST
Sbjct: 334 EQGYYKICRGRNVCGVDSMVST 355
>sp|P04989|CYS2_DICDI CYSTEINE PROTEINASE 2 PRECURSOR (PRESTALK CATHEPSIN)
Length = 376
Score = 398 bits (1012), Expect = e-111
Identities = 145/386 (37%), Positives = 211/386 (54%), Gaps = 55/386 (14%)
Query: 1 MKVILLFVLAVFTVFVSSRGIP-------PEEQSQFLEFQDKFNKKYSHEEYLERFEIFK 53
M++++ +L +F F + P + ++ F E+ KFN++YS E+ R+ IFK
Sbjct: 1 MRLLVFLILLIFVNFSFANVRPNGRRFSESQYRTAFTEWTLKFNRQYSSSEFSNRYSIFK 60
Query: 54 SNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKE-AIFTDDLPVADYLDD 112
SN+ ++ N + T G+N FAD++++E++ YL + A + + L+
Sbjct: 61 SNMDYVDNWNSK---GDSQTVLGLNNFADITNEEYRKTYLGTRVNAHSYNGYDGREVLNV 117
Query: 113 EFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVD 172
E + + P + DWRT+ AVTP+K+QGQCGSCWSFSTTG+ EG H + KLVSLSEQNLVD
Sbjct: 118 EDLQTNPKSIDWRTKNAVTPIKDQGQCGSCWSFSTTGSTEGAHALKTKKLVSLSEQNLVD 177
Query: 173 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG 232
C + GC+GGL NA++YIIKN GI TESSYPYTAETG+ C FN ++IG
Sbjct: 178 CSGPEENF--------GCDGGLMNNAFDYIIKNKGIDTESSYPYTAETGSTCLFNKSDIG 229
Query: 233 AKISNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGIL 289
A I + I + GP+++A DA +Q Y G++ P C+P LDHG+L
Sbjct: 230 ATIKGYVNITAGSEISLENGAQHGPVSVAIDASHNSFQLYTSGIYYEPKCSPTELDHGVL 289
Query: 290 IVGYSA--------------------------------KNTIFRKNMPYWIVKNSWGADW 317
+VGY +++ K YWIVKNSWG W
Sbjct: 290 VVGYGVQGKDDEGPVLNRKQTIVIHKNEDNKVESSDDSSDSVRPKANNYWIVKNSWGTSW 349
Query: 318 GEQGYIYLRRG-KNTCGVSNFVSTSI 342
G +GYI + + KN CG+++ S +
Sbjct: 350 GIKGYILMSKDRKNNCGIASVSSYPL 375
>sp|P43236|CATK_RABIT CATHEPSIN K PRECURSOR (OC-2 PROTEIN)
Length = 329
Score = 395 bits (1005), Expect = e-110
Identities = 118/341 (34%), Positives = 178/341 (51%), Gaps = 25/341 (7%)
Query: 9 LAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
L V + V S + PEE +Q+ ++ ++K+Y+ + + + R I++ NL I NL
Sbjct: 4 LKVLLLPVVSFALHPEEILDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLE 63
Query: 66 AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWR 125
A + +N D++S+E K Y+ ++ P + D+R
Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSRSHSNDTLYIP-DWEGRTPDSIDYR 122
Query: 126 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEA 185
+G VTPVKNQGQCGSCW+FS+ G +EGQ KL++LS QNLVDC E
Sbjct: 123 KKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--------- 173
Query: 186 CDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP-KN 244
+ GC GG NA+ Y+ +N GI +E +YPY + C +N AK + IP N
Sbjct: 174 -NYGCGGGYMTNAFQYVQRNRGIDSEDAYPYVGQD-ESCMYNPTGKAAKCRGYREIPEGN 231
Query: 245 ETVMAGYIVSTGPLAIAADAV--EWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFR 301
E + + GP+++A DA +QFY GV +D C+ ++++H +L VGY +
Sbjct: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDENCSSDNVNHAVLAVGYG-----IQ 286
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVSTS 341
K +WI+KNSWG WG +GYI + R KN CG++N S
Sbjct: 287 KGNKHWIIKNSWGESWGNKGYILMARNKNNACGIANLASFP 327
>sp|P54640|CYS5_DICDI CYSTEINE PROTEINASE 5 PRECURSOR
Length = 344
Score = 394 bits (1001), Expect = e-109
Identities = 138/362 (38%), Positives = 200/362 (55%), Gaps = 37/362 (10%)
Query: 1 MKVI-LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKI 59
MKV+ L VL V + + ++ F ++ K Y+ EE+ R+ IF +N+ +
Sbjct: 1 MKVLSFLCVLLVSVATAKQQFSELQYRNAFTDWMITHQKSYTSEEFGARYNIFTANMDYV 60
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
++ N + ++T G+N FAD++++E++N YL K F + + NS
Sbjct: 61 QQWN----SKGSETVLGLNNFADITNEEYRNTYLGTK---FDASSLIGTQEEKVHTNSSA 113
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
+ DWR+ GAVTPVKNQGQCG CWSFSTTG+ EG HF S+ +LVSLSEQNL+DC E
Sbjct: 114 ASKDWRSEGAVTPVKNQGQCGGCWSFSTTGSTEGAHFQSKGELVSLSEQNLIDCSTE--- 170
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
+ GC+GGL A+ YII N GI TESSYPY AE G +C + S N GA +S++
Sbjct: 171 -------NSGCDGGLMTYAFEYIINNNGIDTESSYPYKAENG-KCEYKSENSGATLSSYK 222
Query: 240 MIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGYS-- 294
+ V+ P+++A DA +Q Y G++ P C+ +LDHG+L VGY
Sbjct: 223 TVTAGSESSLESAVNVNPVSVAIDASHQSFQLYTSGIYYEPECSSENLDHGVLAVGYGSG 282
Query: 295 ------------AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTS 341
+ N + YWIVKNSWG WG +GYI + R + N CG+++ S
Sbjct: 283 SGSSSGQSSGQSSGNLSASSSNEYWIVKNSWGTSWGIEGYILMSRNRDNNCGIASSASFP 342
Query: 342 II 343
++
Sbjct: 343 VV 344
>sp|P13277|CYS1_HOMAM DIGESTIVE CYSTEINE PROTEINASE 1 PRECURSOR
Length = 322
Score = 393 bits (998), Expect = e-109
Identities = 130/351 (37%), Positives = 186/351 (52%), Gaps = 37/351 (10%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKI 59
MKV+ LF+ + + + EF+ KF +KY EE R +F NL I
Sbjct: 1 MKVVALFLFGLALAAANPS---------WEEFKGKFGRKYVDLEEERYRLNVFLDNLQYI 51
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
EE N + +N+F+D+++++F K+ + + ++ P
Sbjct: 52 EEFNKKYERGEVTYNLAINQFSDMTNEKFNAVMKGYKKGPRPAAVFTS-------TDAAP 104
Query: 120 TA--FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
+ DWRT+GAVTPVK+QGQCGSCW+FSTTG +EGQHF+ +LVSLSEQ LVDC
Sbjct: 105 ESTEVDWRTKGAVTPVKDQGQCGSCWAFSTTGGIEGQHFLKTGRLVSLSEQQLVDC---- 160
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN 237
G ++GCNGG A Y+ NGG+ TESSYPY A T C FNS IGA +
Sbjct: 161 ---AGGSYYNQGCNGGWVERAIMYVRDNGGVDTESSYPYEARDNT-CRFNSNTIGATCTG 216
Query: 238 FTMIPK-NETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGY 293
+ I + +E+ + GP+++A DA +Q Y GV+ P C+ + LDH +L VGY
Sbjct: 217 YVGIAQGSESALKTATRDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGY 276
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 343
++ +W+VKNSW WGE GYI + R + N CG++ +
Sbjct: 277 GSEG-----GQDFWLVKNSWATSWGESGYIKMARNRNNNCGIATDACYPTV 322
>sp|P25784|CYS3_HOMAM DIGESTIVE CYSTEINE PROTEINASE 3 PRECURSOR
Length = 321
Score = 392 bits (997), Expect = e-109
Identities = 126/348 (36%), Positives = 185/348 (52%), Gaps = 32/348 (9%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKI 59
MKV LF+ + S + F+ ++ +KY +E L R +F+ N I
Sbjct: 1 MKVAALFLCGLALATASPS---------WDHFKTQYGRKYGDAKEELYRQRVFQQNEQLI 51
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
E+ N N + K +N+F D++++EF K+ + +
Sbjct: 52 EDFNKKFENGEVTFKVAMNQFGDMTNEEFNAVMKGYKKG----SRGEPKAVFTAEAGPMA 107
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
DWRT+ VTPVK+Q QCGSCW+FS TG +EGQHF+ ++LVSLSEQ LVDC
Sbjct: 108 ADVDWRTKALVTPVKDQEQCGSCWAFSATGALEGQHFLKNDELVSLSEQQLVDCST---- 163
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
+ ++GC GG +A++YI NGGI TESSYPY AE C F++ +IGA +
Sbjct: 164 ----DYGNDGCGGGWMTSAFDYIKDNGGIDTESSYPYEAED-RSCRFDANSIGAICTGSV 218
Query: 240 MIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDI-PCNPNSLDHGILIVGYSAK 296
+ E + + GP+++A DA +QFY GV+ C+P LDHG+L VGY +
Sbjct: 219 EVQHTEEALQEAVSGVGPISVAIDASHFSFQFYSSGVYYEQNCSPTFLDHGVLAVGYGTE 278
Query: 297 NTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 343
+T YW+VKNSWG+ WG+ GYI + R + N CG+++ S +
Sbjct: 279 ST-----KDYWLVKNSWGSSWGDAGYIKMSRNRDNNCGIASEPSYPTV 321
>sp|P25774|CATS_HUMAN CATHEPSIN S PRECURSOR
Length = 331
Score = 392 bits (996), Expect = e-109
Identities = 112/342 (32%), Positives = 172/342 (49%), Gaps = 21/342 (6%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELN 63
L+ VL V + V+ P + ++ + K+Y E R I++ NL + N
Sbjct: 4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63
Query: 64 LIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD 123
L G+N D++S+E + + + + +P + D
Sbjct: 64 LEHSMGMHSYDLGMNHLGDMTSEEVMSLTSSLRVPSQWQRNITYKSNPNRI---LPDSVD 120
Query: 124 WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE 183
WR +G VT VK QG CG+CW+FS G +E Q + KLV+LS QNLVDC E
Sbjct: 121 WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDCSTE------- 173
Query: 184 EACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP- 242
+ ++GCNGG A+ YII N GI +++SYPY A +C ++S A S +T +P
Sbjct: 174 KYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMD-QKCQYDSKYRAATCSKYTELPY 232
Query: 243 KNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF 300
E V+ + + GP+++ DA + Y GV+ P +++HG+L+VGY N
Sbjct: 233 GREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLN--- 289
Query: 301 RKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTS 341
YW+VKNSWG ++GE+GYI + R K N CG+++F S
Sbjct: 290 --GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYP 329
>sp|P15242|TES1_RAT TESTIN 1/2 PRECURSOR (CMB-22/CMB-23)
Length = 333
Score = 391 bits (995), Expect = e-109
Identities = 112/347 (32%), Positives = 175/347 (50%), Gaps = 20/347 (5%)
Query: 3 VILLFVLAVFTVFVSSRGI--PPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
+I + LA+ + V S P ++ E++ K K Y+ E + +++ N IE
Sbjct: 1 MIAVLFLAILCLEVDSTAPTPDPSLDVEWNEWRTKHGKTYNMNEERLKRAVWEKNFKMIE 60
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPT 120
N + + D +N F DL++ EF + D +P
Sbjct: 61 LHNWEYLEGRHDFTMAMNAFGDLTNIEFVKMMTG----FQRQKIKKTHIFQDHQFLYVPK 116
Query: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
DWR G VTPVKNQG C S W+FS TG++EGQ F +L+ LSEQNL+DC + +
Sbjct: 117 RVDWRQLGYVTPVKNQGHCASSWAFSATGSLEGQMFRKTERLIPLSEQNLLDCMGSNVTH 176
Query: 181 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTM 240
GC+GG A+ Y+ NGG+ TE SYPY + G +C +++ N A + +F
Sbjct: 177 --------GCSGGFMQYAFQYVKDNGGLATEESYPYRGQ-GRECRYHAENSAANVRDFVQ 227
Query: 241 IPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGYSAKN 297
IP +E + + GP+++A DA +QFY G++ P C L+H +L+VGY +
Sbjct: 228 IPGSEEALMKAVAKVGPISVAVDASHGSFQFYGSGIYYEPQCKRVHLNHAVLVVGYGFE- 286
Query: 298 TIFRKNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 343
+W+VKNSWG +WG +GY+ L + N CG++ + + I+
Sbjct: 287 GEESDGNSFWLVKNSWGEEWGMKGYMKLAKDWSNHCGIATYSTYPIV 333
>sp|Q10716|CYS1_MAIZE CYSTEINE PROTEINASE 1 PRECURSOR
Length = 371
Score = 391 bits (993), Expect = e-108
Identities = 141/368 (38%), Positives = 201/368 (54%), Gaps = 34/368 (9%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEE-------------------QSQFLEFQDKFNKKYS 41
M +L +L++ + + + E+ +S FL F +F K Y
Sbjct: 1 MAHRVLLLLSLASAAAVAAAVDAEDPLIRQVVPGGDDNDLELNAESHFLSFVQRFGKSYK 60
Query: 42 H-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLN---NKE 97
+E+ R +FK NL + L+ + GV KF+DL+ EF+ YL ++
Sbjct: 61 DADEHAYRLSVFKDNLRRARRHQLLDP----SAEHGVTKFSDLTPAEFRRTYLGLRKSRR 116
Query: 98 AIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFI 157
A+ + A + +P FDWR GAV PVKNQG CGSCWSFS +G +EG H++
Sbjct: 117 ALLRELGESAHEAPVLPTDGLPDDFDWRDHGAVGPVKNQGSCGSCWSFSASGALEGAHYL 176
Query: 158 SQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYT 217
+ KL LSEQ VDCDHEC + ++CD GCNGGL A++Y+ K GG+++E YPYT
Sbjct: 177 ATGKLEVLSEQQFVDCDHEC-DSSEPDSCDSGCNGGLMTTAFSYLQKAGGLESEKDYPYT 235
Query: 218 AETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDI 277
G +C F+ + I A + NF+++ +E ++ ++ GPLAI +A Q YIGGV
Sbjct: 236 GSDG-KCKFDKSKIVASVQNFSVVSVDEAQISANLIKHGPLAIGINAAYMQTYIGGVSCP 294
Query: 278 PCNPNSLDHGILIVGYSAKN--TIFRKNMPYWIVKNSWGADWGEQGYIYLRRG---KNTC 332
LDHG+L+VGY A I K+ PYWI+KNSWG +WGE GY + RG +N C
Sbjct: 295 YICGRHLDHGVLLVGYGASGFAPIRLKDKPYWIIKNSWGENWGENGYYKICRGSNVRNKC 354
Query: 333 GVSNFVST 340
GV + VST
Sbjct: 355 GVDSMVST 362
>sp|P12412|CYSP_VIGMU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYSTEINE PROTEINASE)
(SULFHYDRYL-ENDOPEPTIDASE) (SH-EP)
Length = 362
Score = 389 bits (989), Expect = e-108
Identities = 131/360 (36%), Positives = 187/360 (51%), Gaps = 36/360 (10%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQ---------FLEFQDKFNKKYSHEEYLERFEI 51
MK +L VL++ V + E+ + ++ S E +RF +
Sbjct: 3 MKKLLWVVLSLSLVLGVANSFDFHEKDLESEESLWDLYERWRSHHTVSRSLGEKHKRFNV 62
Query: 52 FKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAI---FTDDLPVAD 108
FK+N+ + N + K +NKFAD+++ EF++ Y +K F +
Sbjct: 63 FKANVMHVHNTNKMDKP----YKLKLNKFADMTNHEFRSTYAGSKVNHHKMFRGSQHGSG 118
Query: 109 YLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQ 168
E + S+P + DWR +GAVT VK+QGQCGSCW+FST VEG + I NKLVSLSEQ
Sbjct: 119 TFMYEKVGSVPASVDWRKKGAVTDVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQ 178
Query: 169 NLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNS 228
LVDCD E ++GCNGGL +A+ +I + GGI TES+YPYTA+ GT
Sbjct: 179 ELVDCDKE---------ENQGCNGGLMESAFEFIKQKGGITTESNYPYTAQEGTCDESKV 229
Query: 229 ANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDH 286
++ I +P N+ V+ P+++A DA ++QFY GVF C L+H
Sbjct: 230 NDLAVSIDGHENVPVNDENALLKAVANQPVSVAIDAGGSDFQFYSEGVFTGDC-NTDLNH 288
Query: 287 GILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVSNFVSTSI 342
G+ IVGY YWIV+NSWG +WGEQGYI ++R + CG++ S I
Sbjct: 289 GVAIVGYGTTV----DGTNYWIVRNSWGPEWGEQGYIRMQRNISKKEGLCGIAMMASYPI 344
>sp|P43297|RD21_ARATH CYSTEINE PROTEINASE RD21A PRECURSOR
Length = 462
Score = 387 bits (984), Expect = e-107
Identities = 120/330 (36%), Positives = 167/330 (50%), Gaps = 29/330 (8%)
Query: 22 PPEEQSQFLEFQDKFNKKYSHE---EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN 78
E S + + K K S E RFEIFK NL ++E N + + G+
Sbjct: 43 EAEVMSIYEAWLVKHGKAQSQNSLVEKDRRFEIFKDNLRFVDEHNEKNL----SYRLGLT 98
Query: 79 KFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQ 138
+FADL++DE+++ YL K + + + + +P + DWR +GAV VK+QG
Sbjct: 99 RFADLTNDEYRSKYLGAKME-KKGERRTSLRYEARVGDELPESIDWRKKGAVAEVKDQGG 157
Query: 139 CGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNA 198
CGSCW+FST G VEG + I L++LSEQ LVDCD + +EGCNGGL A
Sbjct: 158 CGSCWAFSTIGAVEGINQIVTGDLITLSEQELVDCD---------TSYNEGCNGGLMDYA 208
Query: 199 YNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPL 258
+ +IIKNGGI T+ YPY GT I ++ +P V+ P+
Sbjct: 209 FEFIIKNGGIDTDKDYPYKGVDGTCDQIRKNAKVVTIDSYEDVPTYSEESLKKAVAHQPI 268
Query: 259 AIAADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGAD 316
+IA +A +Q Y G+FD C LDHG++ VGY +N YWIV+NSWG
Sbjct: 269 SIAIEAGGRAFQLYDSGIFDGSCG-TQLDHGVVAVGYGTEN-----GKDYWIVRNSWGKS 322
Query: 317 WGEQGYIYLRRG----KNTCGVSNFVSTSI 342
WGE GY+ + R CG++ S I
Sbjct: 323 WGESGYLRMARNIASSSGKCGIAIEPSYPI 352
>sp|P55097|CATK_MOUSE CATHEPSIN K PRECURSOR
Length = 329
Score = 384 bits (976), Expect = e-106
Identities = 115/341 (33%), Positives = 178/341 (51%), Gaps = 25/341 (7%)
Query: 9 LAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
L V + + S + PEE +Q+ ++ K+Y+ + + + R I++ NL +I NL
Sbjct: 4 LKVLLLPMVSFALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLE 63
Query: 66 AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWR 125
A + +N D++S+E + Y E+ +P + D+R
Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIPPSRSYSNDTLYTP-EWEGRVPDSIDYR 122
Query: 126 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEA 185
+G VTPVKNQGQCGSCW+FS+ G +EGQ KL++LS QNLVDC E
Sbjct: 123 KKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE--------- 173
Query: 186 CDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP-KN 244
+ GC GG A+ Y+ +NGGI +E ++PY + C +N+ AK + IP N
Sbjct: 174 -NYGCGGGYMTTAFQYVQQNGGIDSEDAFPYVGQD-ESCMYNATAKAAKCRGYREIPVGN 231
Query: 245 ETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFR 301
E + + GP++++ DA +QFY GV +D C+ ++++H +L+VGY +
Sbjct: 232 EKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGT-----Q 286
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVSTS 341
K +WI+KNSWG WG +GY L R KN CG++N S
Sbjct: 287 KGSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFP 327
>sp|P09668|CATH_HUMAN CATHEPSIN H PRECURSOR
Length = 335
Score = 383 bits (974), Expect = e-106
Identities = 119/341 (34%), Positives = 167/341 (48%), Gaps = 28/341 (8%)
Query: 8 VLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAI 67
+L V + + E+ F + K K YS EEY R + F SN KI N
Sbjct: 14 LLGVPVCGAAELSVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHN---- 69
Query: 68 NHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTR 127
N K +N+F+D+S E K+ YL ++ ++YL P + DWR +
Sbjct: 70 NGNHTFKMALNQFSDMSFAEIKHKYLWSEPQ--NCSATKSNYLRGT--GPYPPSVDWRKK 125
Query: 128 GA-VTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEAC 186
G V+PVKNQG CGSCW+FSTTG +E I+ K++SL+EQ LVDC + Y
Sbjct: 126 GNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNY------ 179
Query: 187 DEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP-KNE 245
GC GGL A+ YI+ N GI E +YPY + G C F + + I +E
Sbjct: 180 --GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGY-CKFQPGKAIGFVKDVANITIYDE 236
Query: 246 TVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCN---PNSLDHGILIVGYSAKNTIFR 301
M + P++ A + ++ Y G++ P+ ++H +L VGY KN
Sbjct: 237 EAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKN---- 292
Query: 302 KNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
+PYWIVKNSWG WG GY + RGKN CG++ S I
Sbjct: 293 -GIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPI 332
>sp|O46427|CATH_PIG CATHEPSIN H PRECURSOR
Length = 335
Score = 382 bits (971), Expect = e-106
Identities = 117/336 (34%), Positives = 165/336 (48%), Gaps = 28/336 (8%)
Query: 13 TVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKAD 72
S+ + E+ F + + KKYS EEY R ++F SN KI N
Sbjct: 19 ACGASNLAVSSFEKLHFKSWMVQHQKKYSLEEYHHRLQVFVSNWRKINAHNA----GNHT 74
Query: 73 TKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGA-VT 131
K G+N+F+D+S DE ++ YL ++ +YL P + DWR +G V+
Sbjct: 75 FKLGLNQFSDMSFDEIRHKYLWSEPQ--NCSATKGNYLRGT--GPYPPSMDWRKKGNFVS 130
Query: 132 PVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCN 191
PVKNQG CGSCW+FSTTG +E I+ K++SL+EQ LVDC + GC
Sbjct: 131 PVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNFN--------NHGCQ 182
Query: 192 GGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAG 250
GGL A+ YI N GI E +YPY + C F A + + I N E M
Sbjct: 183 GGLPSQAFEYIRYNKGIMGEDTYPYKGQDD-HCKFQPDKAIAFVKDVANITMNDEEAMVE 241
Query: 251 YIVSTGPLAIAADA-VEWQFYIGGVFDIPCN---PNSLDHGILIVGYSAKNTIFRKNMPY 306
+ P++ A + ++ Y G++ P+ ++H +L VGY +N +PY
Sbjct: 242 AVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEEN-----GIPY 296
Query: 307 WIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
WIVKNSWG WG GY + RGKN CG++ S I
Sbjct: 297 WIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPI 332
>sp|P25803|CYSP_PHAVU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYSTEINE PROTEINASE EP-C1)
Length = 362
Score = 380 bits (966), Expect = e-105
Identities = 128/354 (36%), Positives = 182/354 (51%), Gaps = 32/354 (9%)
Query: 3 VILLFVLAVFTVFVSSRGIP--PEEQSQF---LEFQDKFNKKYSHEEYLERFEIFKSNLG 57
V+L F L + E+S + ++ S E +RF +FK+NL
Sbjct: 9 VVLSFSLVLGVANSFDFHDKDLASEESLWDLYERWRSHHTVSRSLGEKHKRFNVFKANLM 68
Query: 58 KIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNK---EAIFTDDLPVADYLDDEF 114
+ N + K +NKFAD+++ EF++ Y +K +F E
Sbjct: 69 HVHNTNKMDKP----YKLKLNKFADMTNHEFRSTYAGSKVNHPRMFRGTPHENGAFMYEK 124
Query: 115 INSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCD 174
+ S+P + DWR +GAVT VK+QGQCGSCW+FST VEG + I NKLV+LSEQ LVDCD
Sbjct: 125 VVSVPPSVDWRKKGAVTDVKDQGQCGSCWAFSTVVAVEGINQIKTNKLVALSEQELVDCD 184
Query: 175 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAK 234
E ++GCNGGL +A+ +I + GGI TES+YPY A+ GT ++
Sbjct: 185 KE---------ENQGCNGGLMESAFEFIKQKGGITTESNYPYKAQEGTCDASKVNDLAVS 235
Query: 235 ISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDHGILIVG 292
I +P N+ V+ P+++A DA ++QFY GVF C L+HG+ IVG
Sbjct: 236 IDGHENVPANDEDALLKAVANQPVSVAIDAGGSDFQFYSEGVFTGDC-STDLNHGVAIVG 294
Query: 293 YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVSNFVSTSI 342
Y YWIV+NSWG +WGE GYI ++R + CG++ S I
Sbjct: 295 YGTTV----DGTNYWIVRNSWGPEWGEHGYIRMQRNISKKEGLCGIAMLPSYPI 344
>sp|P00786|CATH_RAT CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPSIN BA)
Length = 333
Score = 377 bits (958), Expect = e-104
Identities = 117/324 (36%), Positives = 167/324 (51%), Gaps = 28/324 (8%)
Query: 25 EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
E+ F + + K YS EY R ++F +N KI+ N K G+N+F+D+S
Sbjct: 29 EKFHFTSWMKQHQKTYSSREYSHRLQVFANNWRKIQAHNQRN----HTFKMGLNQFSDMS 84
Query: 85 SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAV-TPVKNQGQCGSCW 143
E K+ YL ++ ++YL P++ DWR +G V +PVKNQG CGSCW
Sbjct: 85 FAEIKHKYLWSEPQ--NCSATKSNYLRGT--GPYPSSMDWRKKGNVVSPVKNQGACGSCW 140
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+FSTTG +E I+ K+++L+EQ LVDC + GC GGL A+ YI+
Sbjct: 141 TFSTTGALESAVAIASGKMMTLAEQQLVDCAQNFN--------NHGCQGGLPSQAFEYIL 192
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAA 262
N GI E SYPY + G QC FN A + N I N E M + P++ A
Sbjct: 193 YNKGIMGEDSYPYIGKNG-QCKFNPEKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAF 251
Query: 263 DAV-EWQFYIGGVFDIPCN---PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 318
+ ++ Y GV+ P+ ++H +L VGY +N + YWIVKNSWG++WG
Sbjct: 252 EVTEDFMMYKSGVYSSNSCHKTPDKVNHAVLAVGYGEQNGLL-----YWIVKNSWGSNWG 306
Query: 319 EQGYIYLRRGKNTCGVSNFVSTSI 342
GY + RGKN CG++ S I
Sbjct: 307 NNGYFLIERGKNMCGLAACASYPI 330
>sp|P25251|CYS4_BRANA CYSTEINE PROTEINASE COT44 PRECURSOR
Length = 328
Score = 376 bits (955), Expect = e-104
Identities = 115/329 (34%), Positives = 167/329 (49%), Gaps = 32/329 (9%)
Query: 29 FLEFQDKFNKKYSH-----EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADL 83
+L + + K S+ + ERF IFK NL I+ N N A K G+ FA+L
Sbjct: 4 YLRWSLEHGKSNSNSNGIINQQDERFNIFKDNLRFIDLHNE--NNKNATYKLGLTIFANL 61
Query: 84 SSDEFKNYYLNNK----EAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQC 139
++DE+++ YL + I Y ++ +P DWR +GAV +K+QG C
Sbjct: 62 TNDEYRSLYLGARTEPVRRITKAKNVNMKYSAAVNVDEVPVTVDWRQKGAVNAIKDQGTC 121
Query: 140 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 199
GSCW+FST VEG + I +LVSLSEQ LVDCD + ++GCNGGL A+
Sbjct: 122 GSCWAFSTAAAVEGINKIVTGELVSLSEQELVDCDK---------SYNQGCNGGLMDYAF 172
Query: 200 NYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLA 259
+I+KNGG+ TE YPY G + + I + +P + VS P++
Sbjct: 173 QFIMKNGGLNTEKDYPYHGTNGKCNSLLKNSRVVTIDGYEDVPSKDETALKRAVSYQPVS 232
Query: 260 IAADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 317
+A DA +Q Y G+F C ++DH ++ VGY ++N + YWIV+NSWG W
Sbjct: 233 VAIDAGGRAFQHYQSGIFTGKCG-TNMDHAVVAVGYGSENGV-----DYWIVRNSWGTRW 286
Query: 318 GEQGYIYLRRG----KNTCGVSNFVSTSI 342
GE GYI + R CG++ S +
Sbjct: 287 GEDGYIRMERNVASKSGKCGIAIEASYPV 315
>sp|P05167|ALEU_HORVU THIOL PROTEASE ALEURAIN PRECURSOR
Length = 362
Score = 375 bits (954), Expect = e-104
Identities = 119/374 (31%), Positives = 179/374 (47%), Gaps = 54/374 (14%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQ---------------------------SQFLEFQDK 35
++ L VLA V V+S + +F F +
Sbjct: 8 LLALAVLATAAVAVASSSSFADSNPIRPVTDRAASTLESAVLGALGRTRHALRFARFAVR 67
Query: 36 FNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLN 94
+ K Y S E RF IF +L ++ N + ++ G+N+F+D+S +EF+ L
Sbjct: 68 YGKSYESAAEVRRRFRIFSESLEEVRSTNRKGLPYR----LGINRFSDMSWEEFQATRLG 123
Query: 95 NKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQ 154
A T +A ++P DWR G V+PVKNQ CGSCW+FSTTG +E
Sbjct: 124 ---AAQTCSATLAGNHLMRDAAALPETKDWREDGIVSPVKNQAHCGSCWTFSTTGALEAA 180
Query: 155 HFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSY 214
+ + K +SLSEQ LVDC + GCNGGL A+ YI NGGI TE SY
Sbjct: 181 YTQATGKNISLSEQQLVDCAGGFNNF--------GCNGGLPSQAFEYIKYNGGIDTEESY 232
Query: 215 PYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAADAVE-WQFYIG 272
PY G C++ + N ++ + I N E + + P+++A ++ ++ Y
Sbjct: 233 PYKGVNGV-CHYKAENAAVQVLDSVNITLNAEDELKNAVGLVRPVSVAFQVIDGFRQYKS 291
Query: 273 GVFD-IPCN--PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK 329
GV+ C P+ ++H +L VGY +N + PYW++KNSWGADWG+ GY + GK
Sbjct: 292 GVYTSDHCGTTPDDVNHAVLAVGYGVENGV-----PYWLIKNSWGADWGDNGYFKMEMGK 346
Query: 330 NTCGVSNFVSTSII 343
N C ++ S ++
Sbjct: 347 NMCAIATCASYPVV 360
>sp|Q10717|CYS2_MAIZE CYSTEINE PROTEINASE 2 PRECURSOR
Length = 360
Score = 374 bits (951), Expect = e-103
Identities = 114/322 (35%), Positives = 168/322 (51%), Gaps = 26/322 (8%)
Query: 28 QFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
+F F ++ K Y S E +RF IF +L + N + + G+N+FAD+S +
Sbjct: 58 RFARFAVRYGKSYESAAEVHKRFRIFSESLQLVRSTNRKGL----SYRLGINRFADMSWE 113
Query: 87 EFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFS 146
EF+ L + ++ ++P DWR G V+PVKNQG CGSCW+FS
Sbjct: 114 EFRATRLGAAQNCSAT--LTGNHRMRAAAVALPETKDWREDGIVSPVKNQGHCGSCWTFS 171
Query: 147 TTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNG 206
TTG +E + + K +SLSEQ LVDC + GCNGGL A+ YI NG
Sbjct: 172 TTGALEAAYTQATGKPISLSEQQLVDCGFAFNNF--------GCNGGLPSQAFEYIKYNG 223
Query: 207 GIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAADAV 265
G+ TE SYPY G C F + N+G K+ + I E + + P+++A + +
Sbjct: 224 GLDTEESYPYQGVNGI-CKFKNENVGVKVLDSVNITLGAEDELKDAVGLVRPVSVAFEVI 282
Query: 266 E-WQFYIGGVFD-IPCN--PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQG 321
++ Y GV+ C P ++H +L VGY ++ + PYW++KNSWGADWG++G
Sbjct: 283 TGFRLYKSGVYTSDHCGTTPMDVNHAVLAVGYGVEDGV-----PYWLIKNSWGADWGDEG 337
Query: 322 YIYLRRGKNTCGVSNFVSTSII 343
Y + GKN CGV+ S I+
Sbjct: 338 YFKMEMGKNMCGVATCASYPIV 359
>sp|P25777|ORYB_ORYSA ORYZAIN BETA CHAIN PRECURSOR
Length = 471
Score = 374 bits (951), Expect = e-103
Identities = 112/304 (36%), Positives = 159/304 (51%), Gaps = 23/304 (7%)
Query: 44 EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDD 103
E+ RF +F NL ++ N A + G+N+FADL+++EF+ +L K A
Sbjct: 69 EHERRFLVFWDNLKFVDAHNARADEGGG-FRLGMNRFADLTNEEFRATFLGAKVAER--S 125
Query: 104 LPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLV 163
+ + + +P + DWR +GAV PVKNQGQCGSCW+FS VE + + +++
Sbjct: 126 RAAGERYRHDGVEELPESVDWREKGAVAPVKNQGQCGSCWAFSAVSTVESINQLVTGEMI 185
Query: 164 SLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ 223
+LSEQ LV+C + GCNGGL +A+++IIKNGGI TE YPY A G
Sbjct: 186 TLSEQELVECST--------NGQNSGCNGGLMADAFDFIIKNGGIDTEDDYPYKAVDGKC 237
Query: 224 CNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNP 281
I F +P+N+ V+ P+++A +A E+Q Y GVF C
Sbjct: 238 DINRENAKVVSIDGFEDVPQNDEKSLQKAVAHQPVSVAIEAGGREFQLYHSGVFSGRCG- 296
Query: 282 NSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKN----TCGVSNF 337
SLDHG++ VGY N YWIV+NSWG WGE GY+ + R N CG++
Sbjct: 297 TSLDHGVVAVGYGTDN-----GKDYWIVRNSWGPKWGESGYVRMERNINVTTGKCGIAMM 351
Query: 338 VSTS 341
S
Sbjct: 352 ASYP 355
>sp|Q40143|CYS3_LYCES CYSTEINE PROTEINASE 3 PRECURSOR
Length = 356
Score = 373 bits (948), Expect = e-103
Identities = 123/321 (38%), Positives = 169/321 (52%), Gaps = 28/321 (8%)
Query: 29 FLEFQDKFNKKYSHEEYL-ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
F F + K+Y E + +RFEIF NL I N + K G+N+F DL+ DE
Sbjct: 57 FARFAIRHRKRYDSVEEIKQRFEIFLDNLKMIRSHNRKGL----SYKLGINEFTDLTWDE 112
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
F+ + L A L + +P DWR G V+PVK QG+CGSCW+FST
Sbjct: 113 FRKHKLG---ASQNCSATTKGNLKLTNVV-LPETKDWRKDGIVSPVKAQGKCGSCWTFST 168
Query: 148 TGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGG 207
TG +E + + K +SLSEQ LVDC + GCNGGL A+ YI NGG
Sbjct: 169 TGALEAAYAQAFGKGISLSEQQLVDCAGAFNNF--------GCNGGLPSQAFEYIKFNGG 220
Query: 208 IQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAADAVE 266
+ TE +YPYT + G C F+ ANIG K+ + I E + + P+++A + V+
Sbjct: 221 LDTEEAYPYTGKNGI-CKFSQANIGVKVISSVNITLGAEYELKYAVALVRPVSVAFEVVK 279
Query: 267 -WQFYIGGVF-DIPCN--PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGY 322
++ Y GV+ C P ++H +L VGY +N PYW++KNSWGADWGE GY
Sbjct: 280 GFKQYKSGVYASTECGDTPMDVNHAVLAVGYGVEN-----GTPYWLIKNSWGADWGEDGY 334
Query: 323 IYLRRGKNTCGVSNFVSTSII 343
+ GKN CGV+ S I+
Sbjct: 335 FKMEMGKNMCGVATCASYPIV 355
>sp|P43156|CYSP_HEMSP THIOL PROTEASE SEN102 PRECURSOR
Length = 360
Score = 373 bits (947), Expect = e-103
Identities = 127/352 (36%), Positives = 181/352 (51%), Gaps = 30/352 (8%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQ--SQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
V L F+ ++ + + + E+ + + +++ +E RF +FK N+ I
Sbjct: 12 VALSFLSIAQSIPFTEKDLASEDSLWNLYEKWRTHHTVARDLDEKNRRFNVFKENVKFIH 71
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADY---LDDEFINS 117
E N A K +NKF D+++ EF++ Y +K + E + S
Sbjct: 72 EFNQK---KDAPYKLALNKFGDMTNQEFRSKYAGSKIQHHRSQRGIQKNTGSFMYENVGS 128
Query: 118 IPT-AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
+P + DWR +GAVT VK+QGQCGSCW+FST +VEG + I +LVSLSEQ LVDCD
Sbjct: 129 LPAASIDWRAKGAVTGVKDQGQCGSCWAFSTIASVEGINQIKTGELVSLSEQELVDCD-- 186
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
+ +EGCNGGL A+ +I KN GI TE SYPY + GT + + I
Sbjct: 187 -------TSYNEGCNGGLMDYAFEFIQKN-GITTEDSYPYAEQDGTCASNLLNSPVVSID 238
Query: 237 NFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGYS 294
+P N V+ P++++ +A +QFY GVF C LDHG+ IVGY
Sbjct: 239 GHQDVPANNENALMQAVANQPISVSIEASGYGFQFYSEGVFTGRCG-TELDHGVAIVGYG 297
Query: 295 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVSNFVSTSI 342
A R YWIVKNSWG +WGE GYI ++RG + CG++ S I
Sbjct: 298 AT----RDGTKYWIVKNSWGEEWGESGYIRMQRGISDKRGKCGIAMEASYPI 345
>sp|P49935|CATH_MOUSE CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPSIN BA)
Length = 333
Score = 372 bits (944), Expect = e-103
Identities = 114/324 (35%), Positives = 164/324 (50%), Gaps = 28/324 (8%)
Query: 25 EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
E+ F + + K YS EY R ++F +N KI+ N K +N+F+D+S
Sbjct: 29 EKFHFKSWMKQHQKTYSSVEYNHRLQMFANNWRKIQAHNQRN----HTFKMALNQFSDMS 84
Query: 85 SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAV-TPVKNQGQCGSCW 143
E K+ +L ++ ++YL P++ DWR +G V +PVKNQG C SCW
Sbjct: 85 FAEIKHKFLWSEPQ--NCSATKSNYLRGT--GPYPSSMDWRKKGNVVSPVKNQGACASCW 140
Query: 144 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 203
+FSTTG +E I+ K++SL+EQ LVDC + GC GGL A+ YI+
Sbjct: 141 TFSTTGALESAVAIASGKMLSLAEQQLVDCAQAFN--------NHGCKGGLPSQAFEYIL 192
Query: 204 KNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKN-ETVMAGYIVSTGPLAIAA 262
N GI E SYPY + + C FN A + N I N E M + P++ A
Sbjct: 193 YNKGIMEEDSYPYIGKD-SSCRFNPQKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAF 251
Query: 263 DAV-EWQFYIGGVFDIPCN---PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 318
+ ++ Y GV+ P+ ++H +L VGY +N + YWIVKNSWG+ WG
Sbjct: 252 EVTEDFLMYKSGVYSSKSCHKTPDKVNHAVLAVGYGEQNGLL-----YWIVKNSWGSQWG 306
Query: 319 EQGYIYLRRGKNTCGVSNFVSTSI 342
E GY + RGKN CG++ S I
Sbjct: 307 ENGYFLIERGKNMCGLAACASYPI 330
>sp|P25778|ORYC_ORYSA ORYZAIN GAMMA CHAIN PRECURSOR
Length = 362
Score = 370 bits (940), Expect = e-102
Identities = 110/322 (34%), Positives = 164/322 (50%), Gaps = 27/322 (8%)
Query: 28 QFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
+F F + K+Y E RF IF +L + N + ++ G+N+FAD+S +
Sbjct: 61 RFARFAVRHGKRYGDAAEVQRRFRIFSESLELVRSTNRRGLPYR----LGINRFADMSWE 116
Query: 87 EFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFS 146
EF+ L A +A ++P DWR G V+PVK+QG CGSCW FS
Sbjct: 117 EFQASRLG---AAQNCSATLAGNHRMRDAPALPETKDWREDGIVSPVKDQGHCGSCWPFS 173
Query: 147 TTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNG 206
TTG++E ++ + VSLSEQ L DC + GC+GGL A+ YI NG
Sbjct: 174 TTGSLEARYTQATGPPVSLSEQQLADCATRYNNF--------GCSGGLPSQAFEYIKYNG 225
Query: 207 GIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP-KNETVMAGYIVSTGPLAIAADAV 265
G+ TE +YPYT G C++ N G K+ + I E + + P+++A +
Sbjct: 226 GLDTEEAYPYTGVNGI-CHYKPENAGVKVLDSVNITLVAEDELKNAVGLVRPVSVAFQVI 284
Query: 266 E-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQG 321
++ Y GV+ +P ++H +L VGY +N + PYW++KNSWGADWG+ G
Sbjct: 285 NGFRMYKSGVYTSDHCGTSPMDVNHAVLAVGYGVENGV-----PYWLIKNSWGADWGDNG 339
Query: 322 YIYLRRGKNTCGVSNFVSTSII 343
Y + GKN CG++ S I+
Sbjct: 340 YFTMEMGKNMCGIATCASYPIV 361
>sp|P00785|ACTN_ACTCH ACTINIDAIN PRECURSOR (ACTINIDIN)
Length = 380
Score = 368 bits (936), Expect = e-102
Identities = 116/352 (32%), Positives = 180/352 (50%), Gaps = 29/352 (8%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPP----EEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSN 55
M ++ L + ++ +++ + E ++ + + K+ K Y+ E+ RFEIFK
Sbjct: 10 MSLLFFSTLLILSLAFNAKNLTQRTNDEVKAMYESWLIKYGKSYNSLGEWERRFEIFKET 69
Query: 56 LGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFI 115
L I+E N + K G+N+FADL+ +EF++ YL ++ V++ + F
Sbjct: 70 LRFIDEHNA---DTNRSYKVGLNQFADLTDEEFRSTYLGFTSG--SNKTKVSNRYEPRFG 124
Query: 116 NSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 175
+P+ DWR+ GAV +K+QG+CG CW+FS VEG + I L+SLSEQ L+DC
Sbjct: 125 QVLPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDC-- 182
Query: 176 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKI 235
G GCNGG + + +II NGGI TE +YPYTA+ G I
Sbjct: 183 ------GRTQNTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNLDLQNEKYVTI 236
Query: 236 SNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIPCNPNSLDHGILIVGY 293
+ +P N V+ P+++A DA ++ Y G+F PC ++DH + IVGY
Sbjct: 237 DTYENVPYNNEWALQTAVTYQPVSVALDAAGDAFKHYSSGIFTGPCG-TAIDHAVTIVGY 295
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK---NTCGVSNFVSTSI 342
+ + YWIVKNSW WGE+GY+ + R TCG++ S +
Sbjct: 296 GTEG-----GIDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 342
>sp|P41721|CATV_NPVBM VIRAL CATHEPSIN (V-CATH)
Length = 323
Score = 367 bits (932), Expect = e-101
Identities = 131/342 (38%), Positives = 180/342 (52%), Gaps = 26/342 (7%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELN 63
+LF L V+ V S+ P + + F EF +FNK YS E E L RF+IF+ NL +I
Sbjct: 4 ILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEI---- 59
Query: 64 LIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD 123
I N K+ +NKF+DLS DE Y T + LD P FD
Sbjct: 60 -INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKG-PLEFD 117
Query: 124 WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE 183
WR VT VKNQG CG+CW+F+T G++E Q I N+L++LSEQ ++DCD
Sbjct: 118 WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD--------- 168
Query: 184 EACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN-FTMIP 242
D GCNGGL A+ IIK GG+Q ES YPY A C NS ++ + + I
Sbjct: 169 -FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEA-DNNNCRMNSNKFLVQVKDCYRYII 226
Query: 243 KNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRK 302
E + + GP+ +A DA + Y G+ C + L+H +L+VGY +N
Sbjct: 227 VYEEKLKDLLPLVGPIPMAIDAADIVNYKQGIIKY-CFDSGLNHAVLLVGYGVEN----- 280
Query: 303 NMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN-FVSTSII 343
N+PYW KN+WG DWGE G+ +++ N CG+ N ST++I
Sbjct: 281 NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 322
>sp|Q02765|CATS_RAT CATHEPSIN S PRECURSOR
Length = 330
Score = 365 bits (926), Expect = e-100
Identities = 104/330 (31%), Positives = 161/330 (48%), Gaps = 22/330 (6%)
Query: 18 SRGIPPEEQSQFLEFQD-KFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFG 76
+ P + ++ + + E R I++ NL I NL G
Sbjct: 15 ATAERPTLDHHWDLWKKTRMRRNTDQNEEDVRRLIWEKNLKFIMLHNLEHSMGMHSYSVG 74
Query: 77 VNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQ 136
+N D++ +E Y + + + ++ +P + DWR +G VT VK Q
Sbjct: 75 MNHMGDMTPEEVIGYMGSLRIPRPWNRSGTLKSSSNQT---LPDSVDWREKGCVTNVKYQ 131
Query: 137 GQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQP 196
G CGSCW+FS G +EGQ + KLVSLS QNLVDC E E+ ++GC GG
Sbjct: 132 GSCGSCWAFSAEGALEGQLKLKTGKLVSLSAQNLVDCSTE------EKYGNKGCGGGFMT 185
Query: 197 NAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIP-KNETVMAGYIVST 255
A+ YII + I +E+SYPY A +C ++ N A S + +P +E + + +
Sbjct: 186 EAFQYII-DTSIDSEASYPYKAMD-EKCLYDPKNRAATCSRYIELPFGDEEALKEAVATK 243
Query: 256 GPLAIAADA---VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNS 312
GP+++ D + Y GV+D P +++HG+L+VGY YW+VKNS
Sbjct: 244 GPVSVGIDDASHSSFFLYQSGVYDDPSCTENMNHGVLVVGYGT-----LDGKDYWLVKNS 298
Query: 313 WGADWGEQGYIYLRR-GKNTCGVSNFVSTS 341
WG +G+QGYI + R KN CG++++ S
Sbjct: 299 WGLHFGDQGYIRMARNNKNHCGIASYCSYP 328
>sp|P14658|CYSP_TRYBB CYSTEINE PROTEINASE PRECURSOR
Length = 450
Score = 365 bits (926), Expect = e-100
Identities = 136/346 (39%), Positives = 190/346 (54%), Gaps = 26/346 (7%)
Query: 3 VILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEE 61
V+L + +V + S + + +F F+ K+ K Y +E RF F+ N+ + +
Sbjct: 15 VLLAMAACLASVALGSLHVEESLEMRFAAFKKKYGKVYKDAKEEAFRFRAFEENMEQAK- 73
Query: 62 LNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTA 121
I FGV F+D++ +EF+ Y N + ++ P A
Sbjct: 74 ---IQAAANPYATFGVTPFSDMTREEFRARYRNGASYFAAAQKRLRKTVNVT-TGRAPAA 129
Query: 122 FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYE 181
DWR +GAVTPVK QGQCGSCW+FST GN+EGQ ++ N LVSLSEQ LV CD
Sbjct: 130 VDWREKGAVTPVKVQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDT------ 183
Query: 182 GEEACDEGCNGGLQPNAYNYIIK-NGG-IQTESSYPYTAETGT--QCNFNSANIGAKISN 237
D GCNGGL NA+N+I+ NGG + TE+SYPY + G QC N IGA I++
Sbjct: 184 ----IDSGCNGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITD 239
Query: 238 FTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN 297
+P++E +A Y+ GPLAIA DA + Y GG+ C LDHG+L+VGY+
Sbjct: 240 HVDLPQDEDAIAAYLAENGPLAIAVDAESFMDYNGGIL-TSCTSKQLDHGVLLVGYN--- 295
Query: 298 TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
N PYWI+KNSW WGE GYI + +G N C ++ VS++++
Sbjct: 296 --DNSNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAVV 339
>sp|P25783|CATV_NPVAC VIRAL CATHEPSIN (V-CATH)
Length = 323
Score = 363 bits (923), Expect = e-100
Identities = 129/342 (37%), Positives = 178/342 (51%), Gaps = 26/342 (7%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELN 63
+LF L V+ V S+ + + F EF +FNK Y E E L RF+IF+ NL +I
Sbjct: 4 ILFYLFVYGVVNSAAYDLLKAPNYFEEFVHRFNKDYGSEVEKLRRFKIFQHNLNEI---- 59
Query: 64 LIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD 123
I N K+ +NKF+DLS DE Y I T + LD P FD
Sbjct: 60 -INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPIQTQNFCKVIVLDQPPGKG-PLEFD 117
Query: 124 WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE 183
WR VT VKNQG CG+CW+F+T ++E Q I N+L++LSEQ ++DCD
Sbjct: 118 WRRLNKVTSVKNQGMCGACWAFATLASLESQFAIKHNQLINLSEQQMIDCD--------- 168
Query: 184 EACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN-FTMIP 242
D GCNGGL A+ IIK GG+Q ES YPY A C NS ++ + + I
Sbjct: 169 -FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEA-DNNNCRMNSNKFLVQVKDCYRYIT 226
Query: 243 KNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRK 302
E + + GP+ +A DA + Y G+ C + L+H +L+VGY +N
Sbjct: 227 VYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIKY-CFNSGLNHAVLLVGYGVEN----- 280
Query: 303 NMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN-FVSTSII 343
N+PYW KN+WG DWGE G+ +++ N CG+ N ST++I
Sbjct: 281 NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 322
>sp|P41715|CATV_NPVCF VIRAL CATHEPSIN (V-CATH)
Length = 324
Score = 363 bits (922), Expect = e-100
Identities = 128/343 (37%), Positives = 187/343 (54%), Gaps = 25/343 (7%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKI 59
M I+L++L V ++ + + + F +F KFNK YS E E L RF+IF+ NL +I
Sbjct: 1 MNKIVLYLLVYGAVQCAAYDV-LKAPNYFEDFLHKFNKSYSSESEKLRRFQIFRHNLEEI 59
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
N ++ + ++ +NKFADLS DE + Y + T + LD P
Sbjct: 60 INKN----HNDSTAQYEINKFADLSKDETISKYTGLSLPLQTQNFCEVVVLDRPPDKG-P 114
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
FDWR VT VKNQG CG+CW+F+T G++E Q I N+ ++LSEQ L+DCD
Sbjct: 115 LEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNQFINLSEQQLIDCD----- 169
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN-F 238
D GC+GGL A+ ++ GGIQ ES YPY A G C N+A K+ +
Sbjct: 170 -----FVDAGCDGGLLHTAFEAVMNMGGIQAESDYPYEANNG-DCRANAAKFVVKVKKCY 223
Query: 239 TMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNT 298
I E + + S GP+ +A DA + Y G+ C + L+H +L+VGY+ +N
Sbjct: 224 RYITVFEEKLKDLLRSVGPIPVAIDASDIVNYKRGIMKY-CANHGLNHAVLLVGYAVENG 282
Query: 299 IFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
+ P+WI+KN+WGADWGEQGY +++ N CG+ N + +S
Sbjct: 283 V-----PFWILKNTWGADWGEQGYFRVQQNINACGIQNELPSS 320
>sp|P25250|CYS2_HORVU CYSTEINE PROTEINASE EP-B 2 PRECURSOR
Length = 373
Score = 361 bits (918), Expect = e-100
Identities = 121/358 (33%), Positives = 170/358 (46%), Gaps = 38/358 (10%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQSQ---------FLEFQDKFNKKYSHEEYLERFEIFKSN 55
+ VLAV V + S IP E++ + +Q + H E RF FKSN
Sbjct: 14 VAAVLAVAAVELCS-AIPMEDKDLESEEALWDLYERWQSAHRVRRHHAEKHRRFGTFKSN 72
Query: 56 LGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFI 115
I N + +N+F D+ EF+ ++ + P +
Sbjct: 73 AHFIHSHNKR---GDHPYRLHLNRFGDMDQAEFRATFVGDLRRDTPSKPPSVPGFMYAAL 129
Query: 116 N--SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDC 173
N +P + DWR +GAVT VK+QG+CGSCW+FST +VEG + I LVSLSEQ L+DC
Sbjct: 130 NVSDLPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDC 189
Query: 174 DHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ---CNFNSAN 230
D A ++GC GGL NA+ YI NGG+ TE++YPY A GT ++
Sbjct: 190 D---------TADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSP 240
Query: 231 IGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIPCNPNSLDHGI 288
+ I +P N V+ P+++A +A + FY GVF C LDHG+
Sbjct: 241 VVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGECG-TELDHGV 299
Query: 289 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK----NTCGVSNFVSTSI 342
+VGY + YW VKNSWG WGEQGYI + + CG++ S +
Sbjct: 300 AVVGYG----VAEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPV 353
>sp|P25249|CYS1_HORVU CYSTEINE PROTEINASE EP-B 1 PRECURSOR
Length = 371
Score = 361 bits (917), Expect = 1e-99
Identities = 121/358 (33%), Positives = 170/358 (46%), Gaps = 38/358 (10%)
Query: 5 LLFVLAVFTVFVSSRGIPPEEQSQ---------FLEFQDKFNKKYSHEEYLERFEIFKSN 55
+ VLAV V + S IP E++ + +Q + H E RF FKSN
Sbjct: 14 VAAVLAVAAVELCS-AIPMEDKDLESEEALWDLYERWQSAHRVRRHHAEKHRRFGTFKSN 72
Query: 56 LGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFI 115
I N + +N+F D+ EF+ ++ + P +
Sbjct: 73 AHFIHSHNKR---GDHPYRLHLNRFGDMDQAEFRATFVGDLRRDTPAKPPSVPGFMYAAL 129
Query: 116 N--SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDC 173
N +P + DWR +GAVT VK+QG+CGSCW+FST +VEG + I LVSLSEQ L+DC
Sbjct: 130 NVSDLPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDC 189
Query: 174 DHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ---CNFNSAN 230
D A ++GC GGL NA+ YI NGG+ TE++YPY A GT ++
Sbjct: 190 D---------TADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSP 240
Query: 231 IGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIPCNPNSLDHGI 288
+ I +P N V+ P+++A +A + FY GVF C LDHG+
Sbjct: 241 VVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGDCG-TELDHGV 299
Query: 289 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK----NTCGVSNFVSTSI 342
+VGY + YW VKNSWG WGEQGYI + + CG++ S +
Sbjct: 300 AVVGYG----VAEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPV 353
>sp|Q26534|CATL_SCHMA CATHEPSIN L PRECURSOR (SMCL1)
Length = 319
Score = 361 bits (916), Expect = 2e-99
Identities = 128/326 (39%), Positives = 190/326 (58%), Gaps = 22/326 (6%)
Query: 21 IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKF 80
+P ++++F+ K+ K+Y E RF IFKSN+ K + L + + +GV +
Sbjct: 12 LPGNVDEKYVQFKLKYRKQYHETEDEIRFNIFKSNILKAQ---LYQVFVRGSAIYGVTPY 68
Query: 81 ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCG 140
+DL++DEF +L + + L E +N+IP FDWR +GAVT VKNQG CG
Sbjct: 69 SDLTTDEFARTHLTASWVVPSSRSNTPTSLGKE-VNNIPKNFDWREKGAVTEVKNQGMCG 127
Query: 141 SCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYN 200
SCW+FSTTGNVE Q F KL+SLSEQ LVDCD D+GCNGGL NAY
Sbjct: 128 SCWAFSTTGNVESQWFRKTGKLLSLSEQQLVDCDG----------LDDGCNGGLPSNAYE 177
Query: 201 YIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAI 260
IIK GG+ E +YPY A+ +C+ + + I++ + ++ET +A ++ +++
Sbjct: 178 SIIKMGGLMLEDNYPYDAKN-EKCHLKTDGVAVYINSSVNLTQDETELAAWLYHNSTISV 236
Query: 261 AADAVEWQFYIGGV---FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 317
+A+ QFY G+ + I C+ LDH +L+VGY + KN P+WIVKNSWG +W
Sbjct: 237 GMNALLLQFYQHGISHPWWIFCSKYLLDHAVLLVGYG----VSEKNEPFWIVKNSWGVEW 292
Query: 318 GEQGYIYLRRGKNTCGVSNFVSTSII 343
GE GY + RG +CG++ ++++I
Sbjct: 293 GENGYFRMYRGDGSCGINTVATSAMI 318
>sp|P25779|CYSP_TRYCR CRUZIPAIN PRECURSOR (MAJOR CYSTEINE PROTEINASE) (CRUZAINE)
Length = 467
Score = 356 bits (904), Expect = 4e-98
Identities = 133/350 (38%), Positives = 184/350 (52%), Gaps = 30/350 (8%)
Query: 3 VILLFVLAVFTVFV----SSRGIPPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLG 57
++L VL V V +S SQF EF+ K + Y S E R +F+ NL
Sbjct: 8 LLLAAVLVVMACLVPAATASLHAEETLTSQFAEFKQKHGRVYESAAEEAFRLSVFRENLF 67
Query: 58 KIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINS 117
+ FGV F+DL+ +EF++ Y +N A F A +
Sbjct: 68 LARLHAAANPH----ATFGVTPFSDLTREEFRSRY-HNGAAHFAAAQERARVPVKVEVVG 122
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
P A DWR RGAVT VK+QGQCGSCW+FS GNVE Q F++ + L +LSEQ LV CD
Sbjct: 123 APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDK-- 180
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETG--TQCNFNSANIGA 233
D GC+GGL NA+ +I++ NG + TE SYPY + G C + +GA
Sbjct: 181 --------TDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGA 232
Query: 234 KISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGY 293
I+ +P++E +A ++ GP+A+A DA W Y GGV C LDHG+L+VGY
Sbjct: 233 TITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVM-TSCVSEQLDHGVLLVGY 291
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
+ + PYWI+KNSW WGE+GYI + +G N C V S++++
Sbjct: 292 NDSAAV-----PYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVV 336
>sp|O10364|CATV_NPVOP VIRAL CATHEPSIN (V-CATH)
Length = 324
Score = 351 bits (890), Expect = 2e-96
Identities = 122/343 (35%), Positives = 181/343 (52%), Gaps = 25/343 (7%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKI 59
M I+L +L V ++ + + + F +F KFNK YS E E L RF+IF+ NL +I
Sbjct: 1 MNKIMLCLLVCGVVHAATYDL-LKAPNYFEDFLHKFNKNYSSESEKLHRFKIFQHNLEEI 59
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
N + + ++ +NKF+DLS +E + Y T + LD + P
Sbjct: 60 INKNQ----NDSTAQYEINKFSDLSKEEAISKYTGLSLPHQTQNFCEVVILDRPP-DRGP 114
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
FDWR VT VKNQG CG+CW+F+T G++E Q I N+L++LSEQ +DCD
Sbjct: 115 LEFDWRQFNKVTSVKNQGVCGACWAFATLGSLESQFAIKYNRLINLSEQQFIDCDR---- 170
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKI-SNF 238
+ GC+GGL A+ ++ GG+Q ES YPY G QC N + S
Sbjct: 171 ------VNAGCDGGLLHTAFESAMEMGGVQMESDYPYETANG-QCRINPNRFVVGVRSCR 223
Query: 239 TMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNT 298
I E + + + GP+ +A DA + Y G+ C + L+H +L+VGY+ +N
Sbjct: 224 RYIVMFEEKLKDLLRAVGPIPVAIDASDIVNYRRGIMR-QCANHGLNHAVLLVGYAVEN- 281
Query: 299 IFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
N+PYWI+KN+WG DWGE GY +++ N CG+ N + +S
Sbjct: 282 ----NIPYWILKNTWGTDWGEDGYFRVQQNINACGIRNELVSS 320
>sp|P36400|LCPB_LEIME CYSTEINE PROTEINASE B PRECURSOR
Length = 443
Score = 348 bits (883), Expect = 1e-95
Identities = 123/348 (35%), Positives = 184/348 (52%), Gaps = 28/348 (8%)
Query: 4 ILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEEL 62
++ VLA + + + F EF+ + + Y E +R F+ NL + E
Sbjct: 13 VVCVVLAAACAPARAIHVGTPAAALFEEFKRTYGRAYETLAEEQQRLANFERNLELMREH 72
Query: 63 NLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDE--FINSIPT 120
+ +FG+ KF DLS EF YLN A + ++++P
Sbjct: 73 QARNPH----AQFGITKFFDLSEAEFAARYLNGAAYFAAAKRHAAQHYRKARADLSAVPD 128
Query: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
A DWR +GAVTPVK+QG CGSCW+FS GN+EGQ +++ ++LVSLSEQ LV CD
Sbjct: 129 AVDWREKGAVTPVKDQGACGSCWAFSAVGNIEGQWYLAGHELVSLSEQQLVSCDD----- 183
Query: 181 EGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETG---TQCNFNSANIGAKI 235
++GC+GGL A++++++ NG + TE SYPY + G N + +GA+I
Sbjct: 184 -----MNDGCDGGLMLQAFDWLLQNTNGHLHTEDSYPYVSGNGYVPECSNSSELVVGAQI 238
Query: 236 SNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSA 295
+I +E MA ++ GP+AIA DA + Y GV C L+HG+L+VGY
Sbjct: 239 DGHVLIGSSEKAMAAWLAKNGPIAIALDASSFMSYKSGVL-TACIGKQLNHGVLLVGYDM 297
Query: 296 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
+ PYW++KNSWG DWGEQGY+ + G N C +S + ++ +
Sbjct: 298 TGEV-----PYWVIKNSWGGDWGEQGYVRVVMGVNACLLSEYPVSAHV 340
>sp|P25775|LCPA_LEIME CYSTEINE PROTEINASE A PRECURSOR
Length = 354
Score = 348 bits (883), Expect = 1e-95
Identities = 143/355 (40%), Positives = 190/355 (53%), Gaps = 36/355 (10%)
Query: 5 LLFVLAVFTVFVSSRGI-------PPEEQ----SQFLEFQDKFNKKYSHE-EYLERFEIF 52
LLF + V +FV G PP + + + F+ + K + + E RF F
Sbjct: 7 LLFAIVVTILFVVCYGSALIAQTPPPVDNFVASAHYGSFKKRHGKAFGGDAEEGHRFNAF 66
Query: 53 KSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDD 112
K N+ LN + D KFADL+ EF YLN D D
Sbjct: 67 KQNMQTAYFLNTQNPHAHYDVS---GKFADLTPQEFAKLYLNPDYYARHLKNHKEDVHVD 123
Query: 113 EFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVD 172
+ S + DWR +GAVTPVKNQG CGSCW+FS GN+EGQ S + LVSLSEQ LV
Sbjct: 124 DSAPSGVMSVDWRDKGAVTPVKNQGLCGSCWAFSAIGNIEGQWAASGHSLVSLSEQMLVS 183
Query: 173 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETGTQ--CNFNS 228
CD DEGCNGGL A N+I++ NG + TE+SYPYT+ GT+ C+ +
Sbjct: 184 CD----------NIDEGCNGGLMDQAMNWIMQSHNGSVFTEASYPYTSGGGTRPPCH-DE 232
Query: 229 ANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGI 288
+GAKI+ F +P +E +A ++ GP+A+A DA WQ Y GGV C SL+HG+
Sbjct: 233 GEVGAKITGFLSLPHDEERIAEWVEKRGPVAVAVDATTWQLYFGGVVS-LCLAWSLNHGV 291
Query: 289 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
LIVG++ PYWIVKNSWG+ WGE+GYI L G N C + N+ ++ +
Sbjct: 292 LIVGFN-----KNAKPPYWIVKNSWGSSWGEKGYIRLAMGSNQCMLKNYPVSATV 341
>sp|Q05094|CYS2_LEIPI CYSTEINE PROTEINASE 2 PRECURSOR (AMASTIGOTE CYSTEINE PROTEINASE
A-2)
Length = 444
Score = 347 bits (882), Expect = 2e-95
Identities = 124/349 (35%), Positives = 187/349 (53%), Gaps = 29/349 (8%)
Query: 4 ILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEEL 62
++ VLA + + + F EF+ + + Y E +R F+ NL + E
Sbjct: 13 VVCVVLAAACAPARAIHVGTPAAALFEEFKRTYGRAYETLAEEQQRLANFERNLELMREH 72
Query: 63 NLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDE--FINSIPT 120
+ +FG+ KF DLS EF YLN A + ++++P
Sbjct: 73 QARNPH----AQFGITKFFDLSEAEFAARYLNGAAYFAAAKRHAAQHYRKARADLSAVPD 128
Query: 121 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 180
A DWR +GAVTPVK+QG CGSCW+FS GN+EGQ +++ ++LVSLSEQ LV CD
Sbjct: 129 AVDWREKGAVTPVKDQGACGSCWAFSAVGNIEGQWYLAGHELVSLSEQQLVSCDD----- 183
Query: 181 EGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETG--TQCNFNSAN--IGAK 234
++GC+GGL A++++++ NG + TE SYPY + G +C+ +S +GA+
Sbjct: 184 -----MNDGCDGGLMLQAFDWLLQNTNGHLHTEDSYPYVSGNGYVPECSNSSEELVVGAQ 238
Query: 235 ISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYS 294
I +I +E MA ++ GP+AIA DA + Y GV C L+HG+L+VGY
Sbjct: 239 IDGHVLIGSSEKAMAAWLAKNGPIAIALDASSFMSYKSGVL-TACIGKQLNHGVLLVGYD 297
Query: 295 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
+ PYW++KNSWG DWGEQGY+ + G N C +S + ++ +
Sbjct: 298 MTGEV-----PYWVIKNSWGGDWGEQGYVRVVMGVNACLLSEYPVSAHV 341
>sp|P35591|CYS1_LEIPI CYSTEINE PROTEINASE 1 PRECURSOR (AMASTIGOTE CYSTEINE PROTEINASE
A-1)
Length = 354
Score = 347 bits (880), Expect = 3e-95
Identities = 143/355 (40%), Positives = 190/355 (53%), Gaps = 36/355 (10%)
Query: 5 LLFVLAVFTVFVSSRGI-------PPEEQ----SQFLEFQDKFNKKYSHE-EYLERFEIF 52
LLF + V +FV G PP + + + F+ + K + + E RF F
Sbjct: 7 LLFAIVVTILFVVCYGSALIAQTPPPVDNFVASAHYGSFKKRHGKAFGGDAEEGHRFNAF 66
Query: 53 KSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDD 112
K N+ LN + D KFADL+ EF YLN D D
Sbjct: 67 KQNMQTAYFLNTQNPHAHYDVS---GKFADLTPQEFAKLYLNPDYYARHLKDHKEDVHVD 123
Query: 113 EFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVD 172
+ S + DWR +GAVTPVKNQG CGSCW+FS GN+EGQ S + LVSLSEQ LV
Sbjct: 124 DSAPSGVMSVDWRDKGAVTPVKNQGLCGSCWAFSAIGNIEGQWAASGHSLVSLSEQMLVS 183
Query: 173 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETGTQ--CNFNS 228
CD DEGCNGGL A N+I++ NG + TE+SYPYT+ GT+ C+ +
Sbjct: 184 CD----------NIDEGCNGGLMDQAMNWIMQSHNGSVFTEASYPYTSGGGTRPPCH-DE 232
Query: 229 ANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGI 288
+GAKI+ F +P +E +A ++ GP+A+A DA WQ Y GGV C SL+HG+
Sbjct: 233 GEVGAKITGFLSLPHDEERIAEWVEKRGPVAVAVDATTWQLYFGGVVS-LCLAWSLNHGV 291
Query: 289 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
LIVG++ PYWIVKNSWG+ WGE+GYI L G N C + N+ ++ +
Sbjct: 292 LIVGFN-----KNAKPPYWIVKNSWGSSWGEKGYIRLAMGSNQCMLKNYPVSATV 341
>sp|P05994|PAP4_CARPA PAPAYA PROTEINASE IV PRECURSOR (PPIV) (PAPAYA PEPTIDASE B) (GLYCYL
ENDOPEPTIDASE)
Length = 348
Score = 346 bits (879), Expect = 3e-95
Identities = 111/321 (34%), Positives = 163/321 (50%), Gaps = 29/321 (9%)
Query: 29 FLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
F + K NK Y + +E L RFEIFK NL I+E N + + G+N+F+DLS+DE
Sbjct: 48 FNSWMLKHNKNYKNVDEKLYRFEIFKDNLKYIDERNKMINGYW----LGLNEFSDLSNDE 103
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
FK Y+ + +T+ ++++++ ++ +P + DWR +GAVTPVK+QG C SCW+FST
Sbjct: 104 FKEKYVGSLPEDYTNQPYDEEFVNEDIVD-LPESVDWRAKGAVTPVKHQGYCESCWAFST 162
Query: 148 TGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGG 207
VEG + I LV LSEQ LVDCD + GCN G Q + Y+ +N G
Sbjct: 163 VATVEGINKIKTGNLVELSEQELVDCDKQ----------SYGCNRGYQSTSLQYVAQN-G 211
Query: 208 IQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV-- 265
I + YPY A+ T K + + N ++ P+++ ++
Sbjct: 212 IHLRAKYPYIAKQQTCRANQVGGPKVKTNGVGRVQSNNEGSLLNAIAHQPVSVVVESAGR 271
Query: 266 EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
++Q Y GG+F+ C +DH + VGY Y ++KNSWG WGE GYI +
Sbjct: 272 DFQNYKGGIFEGSCG-TKVDHAVTAVGYGKSG-----GKGYILIKNSWGPGWGENGYIRI 325
Query: 326 RRGKNT----CGVSNFVSTSI 342
RR CGV I
Sbjct: 326 RRASGNSPGVCGVYRSSYYPI 346
>sp|P10056|PAP3_CARPA CARICAIN PRECURSOR (PAPAYA PROTEINASE OMEGA) (PAPAYA PROTEINASE
III) (PPIII) (PAPAYA PEPTIDASE A)
Length = 348
Score = 341 bits (865), Expect = 1e-93
Identities = 114/317 (35%), Positives = 162/317 (50%), Gaps = 26/317 (8%)
Query: 29 FLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
F + NK Y + +E L RFEIFK NL I+E N ++ G+N+FADLS+DE
Sbjct: 48 FNSWMLNHNKFYENVDEKLYRFEIFKDNLNYIDETNKKNNSYW----LGLNEFADLSNDE 103
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
F Y+ + + ++++++ +N +P DWR +GAVTPV++QG CGSCW+FS
Sbjct: 104 FNEKYVGSLIDATIEQSYDEEFINEDTVN-LPENVDWRKKGAVTPVRHQGSCGSCWAFSA 162
Query: 148 TGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGG 207
VEG + I KLV LSEQ LVDC+ GC GG P A Y+ KN G
Sbjct: 163 VATVEGINKIRTGKLVELSEQELVDCERR----------SHGCKGGYPPYALEYVAKN-G 211
Query: 208 IQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--V 265
I S YPY A+ GT K S + N ++ P+++ ++
Sbjct: 212 IHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEGNLLNAIAKQPVSVVVESKGR 271
Query: 266 EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
+Q Y GG+F+ PC +DH + VGY Y ++KNSWG WGE+GYI +
Sbjct: 272 PFQLYKGGIFEGPCG-TKVDHAVTAVGYGKSG-----GKGYILIKNSWGTAWGEKGYIRI 325
Query: 326 RRG-KNTCGVSNFVSTS 341
+R N+ GV +S
Sbjct: 326 KRAPGNSPGVCGLYKSS 342
>sp|P14080|PAP2_CARPA CHYMOPAPAIN PRECURSOR (PAPAYA PROTEINASE II) (PPII)
Length = 352
Score = 339 bits (860), Expect = 6e-93
Identities = 119/321 (37%), Positives = 160/321 (49%), Gaps = 29/321 (9%)
Query: 29 FLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
F + K NK Y S +E + RFEIF+ NL I+E N ++ G+N FADLS+DE
Sbjct: 48 FDSWMLKHNKIYESIDEKIYRFEIFRDNLMYIDETNKKNNSYW----LGLNGFADLSNDE 103
Query: 88 FKNYYLNNKEAIFTDDLP-VADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFS 146
FK Y+ FT + + + + P + DWR +GAVTPVKNQG CGSCW+FS
Sbjct: 104 FKKKYVGFVAEDFTGLEHFDNEDFTYKHVTNYPQSIDWRAKGAVTPVKNQGACGSCWAFS 163
Query: 147 TTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNG 206
T VEG + I L+ LSEQ LVDCD GC GG Q + Y+ N
Sbjct: 164 TIATVEGINKIVTGNLLELSEQELVDCDKH----------SYGCKGGYQTTSLQYVANN- 212
Query: 207 GIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA-- 264
G+ T YPY A+ + KI+ + +P N ++ PL++ +A
Sbjct: 213 GVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSNCETSFLGALANQPLSVLVEAGG 272
Query: 265 VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIY 324
+Q Y GVFD PC LDH + VGY + Y I+KNSWG +WGE+GY+
Sbjct: 273 KPFQLYKSGVFDGPCG-TKLDHAVTAVGYGTSD-----GKNYIIIKNSWGPNWGEKGYMR 326
Query: 325 LRR----GKNTCGVSNFVSTS 341
L+R + TCGV
Sbjct: 327 LKRQSGNSQGTCGVYKSSYYP 347
>sp|P00784|PAPA_CARPA PAPAIN PRECURSOR (PAPAYA PROTEINASE I) (PPI)
Length = 345
Score = 334 bits (848), Expect = 1e-91
Identities = 107/321 (33%), Positives = 152/321 (47%), Gaps = 32/321 (9%)
Query: 29 FLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
F + K NK Y + +E + RFEIFK NL I+E N ++ G+N FAD+S+DE
Sbjct: 48 FESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYW----LGLNVFADMSNDE 103
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
FK Y + +T + + ++ +IP DWR +GAVTPVKNQG CGSCW+FS
Sbjct: 104 FKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSA 163
Query: 148 TGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGG 207
+EG I L SEQ L+DCD GCNGG +A + + G
Sbjct: 164 VVTIEGIIKIRTGNLNEYSEQELLDCDRR----------SYGCNGGYPWSALQLVAQ-YG 212
Query: 208 IQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV-- 265
I ++YPY + AK + Y ++ P+++ +A
Sbjct: 213 IHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGK 272
Query: 266 EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
++Q Y GG+F PC N +DH + VGY Y ++KNSWG WGE GYI +
Sbjct: 273 DFQLYRGGIFVGPCG-NKVDHAVAAVGYG---------PNYILIKNSWGTGWGENGYIRI 322
Query: 326 RRGKNT----CGVSNFVSTSI 342
+RG CG+ +
Sbjct: 323 KRGTGNSYGVCGLYTSSFYPV 343
>sp|P22895|P34_SOYBN P34 PROBABLE THIOL PROTEASE PRECURSOR
Length = 379
Score = 331 bits (840), Expect = 1e-90
Identities = 109/334 (32%), Positives = 169/334 (49%), Gaps = 33/334 (9%)
Query: 24 EEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFAD 82
+ S F ++ + + Y +HEE +R EIFK+N I ++N + G+NKFAD
Sbjct: 39 QVSSLFQLWKSEHGRVYHNHEEEAKRLEIFKNNSNYIRDMNA-NRKSPHSHRLGLNKFAD 97
Query: 83 LSSDEFKNYYLNNKEAIFTDDLPVADYLDDE--FINSIPTAFDWRTRGAVTPVKNQGQCG 140
++ EF YL + + + E + P ++DWR +G +T VK QG CG
Sbjct: 98 ITPQEFSKKYLQAPKDVSQQIKMANKKMKKEQYSCDHPPASWDWRKKGVITQVKYQGGCG 157
Query: 141 SCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYN 200
W+FS TG +E H I+ LVSLSEQ LVDC E EG G Q ++
Sbjct: 158 RGWAFSATGAIEAAHAIATGDLVSLSEQELVDCVEE----------SEGSYNGWQYQSFE 207
Query: 201 YIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNF-TMIPKNE------TVMAGYIV 253
+++++GGI T+ YPY A+ G +C N I + T+I +E +
Sbjct: 208 WVLEHGGIATDDDYPYRAKEG-RCKANKIQDKVTIDGYETLIMSDESTESETEQAFLSAI 266
Query: 254 STGPLAIAADAVEWQFYIGGVFDIP--CNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKN 311
P++++ DA ++ Y GG++D +P ++H +L+VGY + + + YWI KN
Sbjct: 267 LEQPISVSIDAKDFHLYTGGIYDGENCTSPYGINHFVLLVGYGSADGV-----DYWIAKN 321
Query: 312 SWGADWGEQGYIYLRRGKNT----CGVSNFVSTS 341
SWG DWGE GYI+++R CG++ F S
Sbjct: 322 SWGFDWGEDGYIWIQRNTGNLLGVCGMNYFASYP 355
>sp|O17473|CATL_BRUPA CATHEPSIN L-LIKE PRECURSOR
Length = 395
Score = 327 bits (829), Expect = 2e-89
Identities = 99/325 (30%), Positives = 153/325 (46%), Gaps = 23/325 (7%)
Query: 25 EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
++++ ++ K Y +E R IF+SN E +N +N ADL+
Sbjct: 87 LETEWKDYVTALGKHYDQKENNFRMAIFESNELMTERINKKYEQGLVSYTTALNDLADLT 146
Query: 85 SDEF--KNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSC 142
+EF +N + +++ + +P DWRT+GAVTPV+NQG+CGSC
Sbjct: 147 DEEFMVRNGLRLPNQTDLRGKRQTSEFYRYDKSERLPDQVDWRTKGAVTPVRNQGECGSC 206
Query: 143 WSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYI 202
++F+T +E H +L+ LS QN+VDC + GC+GG P A+ Y
Sbjct: 207 YAFATAAALEAYHKQMTGRLLDLSPQNIVDC--------TRNLGNNGCSGGYMPTAFQY- 257
Query: 203 IKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMI-PKNETVMAGYIVSTGPLAIA 261
GI ES YPY +C + + + F I P +E + + GP+ +
Sbjct: 258 ASRYGIAMESRYPYVGTE-QRCRWQQSIAVVTDNGFNEIQPGDELALKHAVAKRGPVVVG 316
Query: 262 A--DAVEWQFYIGGVF-DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 318
++FY GV+ + C DH +L VGY + YWIVKNSWG DWG
Sbjct: 317 ISGSKRSFRFYKDGVYSEGNCG--RPDHAVLAVGYGTHPSY----GDYWIVKNSWGTDWG 370
Query: 319 EQGYIYLRRGK-NTCGVSNFVSTSI 342
+ GY+Y+ R + N C +++ S I
Sbjct: 371 KDGYVYMARNRGNMCHIASAASFPI 395
>sp|Q10991|CATL_SHEEP CATHEPSIN L
Length = 217
Score = 325 bits (824), Expect = 1e-88
Identities = 104/230 (45%), Positives = 140/230 (60%), Gaps = 17/230 (7%)
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
+P + DW +G VTPVKNQGQCGSCW+FS TG +EGQ F KLVSLSEQNLVD
Sbjct: 1 VPKSVDWTKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVD----- 55
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN 237
++GCNGGL NA+ YI +NGG+ +E SYPY A T T CN+ AK +
Sbjct: 56 ---SSRPQGNQGCNGGLMDNAFQYIKENGGLDSEESYPYEA-TDTSCNYKPEYSAAKDTG 111
Query: 238 FTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYS 294
F IP+ E + + + GP+++A DA +QFY G+ +D C+ LDHG+L+VGY
Sbjct: 112 FVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYG 171
Query: 295 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 343
+ T N +WIVKNSWG +WG +GY+ + + N CG++ S +
Sbjct: 172 FEGT----NNKFWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|P54639|CYS4_DICDI CYSTEINE PROTEINASE 4 PRECURSOR
Length = 442
Score = 323 bits (819), Expect = 4e-88
Identities = 115/308 (37%), Positives = 166/308 (53%), Gaps = 23/308 (7%)
Query: 1 MKVI-LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKI 59
M+V+ L +L V + + ++ F + + YS EE+ R++IFKSN+ +
Sbjct: 1 MRVLSFLCLLLVSYASAKQQFSELQYRNAFTNWMQAHQRTYSSEEFNARYQIFKSNMDYV 60
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
+ N + +T G+N FAD+++ E++ YL F + + F P
Sbjct: 61 HQWN----SKGGETVLGLNVFADITNQEYRTTYLGTP---FDGSALIGTEEEKIFSTPAP 113
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN---KLVSLSEQNLVDCDHE 176
DWR +GAVTP+KNQGQCG CWSFSTTG+ EG HFI+ LVSLSEQNL+DC
Sbjct: 114 -TVDWRAQGAVTPIKNQGQCGGCWSFSTTGSTEGAHFIASGTKKDLVSLSEQNLIDCSK- 171
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
+ GC GGL + YII N GI TESSYPYTAE G +C F ++NIGA+I
Sbjct: 172 -------SYGNNGCEGGLMTLGFEYIINNKGIDTESSYPYTAEDGKECKFKTSNIGAQIV 224
Query: 237 NFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGY 293
++ + + P+++A DA +Q Y G++ P C P LDHG+L+VGY
Sbjct: 225 SYQNVTSGSEASLQSASNNAPVSVAIDASNESFQLYESGIYYEPACTPTQLDHGVLVVGY 284
Query: 294 SAKNTIFR 301
+ ++
Sbjct: 285 GSGSSSSS 292
Score = 70.2 bits (169), Expect = 6e-12
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 297 NTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTS 341
+ + YWIVKNSWG WG GYI++ + + N CG++ S
Sbjct: 392 GAVEASSGNYWIVKNSWGTSWGMDGYIFMSKDRNNNCGIATMASFP 437
>sp|P56203|CATW_MOUSE CATHEPSIN W PRECURSOR (LYMPHOPAIN)
Length = 371
Score = 319 bits (810), Expect = 4e-87
Identities = 108/340 (31%), Positives = 162/340 (46%), Gaps = 32/340 (9%)
Query: 22 PPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKF 80
P E + F FQ +FN+ Y + EY R IF NL + + L + +FG F
Sbjct: 33 PLELKEVFKLFQIRFNRSYWNPAEYTRRLSIFAHNLAQAQRLQQEDL---GTAEFGETPF 89
Query: 81 ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRT-RGAVTPVKNQGQC 139
+DL+ +EF Y + T ++ + + S+P DWR + ++ VKNQG C
Sbjct: 90 SDLTEEEFGQLYGQERSPERTPNMTK-KVESNTWGESVPRTCDWRKAKNIISSVKNQGSC 148
Query: 140 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 199
CW+ + N++ I + V +S Q L+DC E C GCNGG +AY
Sbjct: 149 KCCWAMAAADNIQALWRIKHQQFVDVSVQELLDC----------ERCGNGCNGGFVWDAY 198
Query: 200 NYIIKNGGIQTESSYPYTAETGT-QCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPL 258
++ N G+ +E YP+ + +C A I +FTM+ NE +A Y+ GP+
Sbjct: 199 LTVLNNSGLASEKDYPFQGDRKPHRCLAKKYKKVAWIQDFTMLSNNEQAIAHYLAVHGPI 258
Query: 259 AIAADAVEWQFYIGGVFDIP---CNPNSLDHGILIVGYSAKNTIFRKNM----------- 304
+ + Q Y GV C+P +DH +L+VG+ K +
Sbjct: 259 TVTINMKLLQHYQKGVIKATPSSCDPRQVDHSVLLVGFGKKKEGMQTGTVLSHSRKRRHS 318
Query: 305 -PYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
PYWI+KNSWGA WGE+GY L RG NTCGV+ + T+ +
Sbjct: 319 SPYWILKNSWGAHWGEKGYFRLYRGNNTCGVTKYPFTAQV 358
>sp|P56202|CATW_HUMAN CATHEPSIN W PRECURSOR (LYMPHOPAIN)
Length = 376
Score = 318 bits (807), Expect = 9e-87
Identities = 114/368 (30%), Positives = 177/368 (47%), Gaps = 44/368 (11%)
Query: 6 LFVLAVFTVFVSSRGI---------PPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSN 55
L L V + RG P E + F FQ +FN+ Y S EE+ R +IF N
Sbjct: 10 LLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHN 69
Query: 56 LGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFI 115
L + + L + +FGV F+DL+ +EF Y + A + + +E
Sbjct: 70 LAQAQRLQEEDL---GTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMG-REIRSEEPE 125
Query: 116 NSIPTAFDWRT-RGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCD 174
S+P + DWR GA++P+K+Q C CW+ + GN+E IS V +S L+DC
Sbjct: 126 ESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVHELLDCG 185
Query: 175 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGT-QCNFNSANIGA 233
C +GC+GG +A+ ++ N G+ +E YP+ + +C+ A
Sbjct: 186 R----------CGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVA 235
Query: 234 KISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFD---IPCNPNSLDHGILI 290
I +F M+ NE +A Y+ + GP+ + + Q Y GV C+P +DH +L+
Sbjct: 236 WIQDFIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLL 295
Query: 291 VGYSA--------KNTIFRKN-------MPYWIVKNSWGADWGEQGYIYLRRGKNTCGVS 335
VG+ + T+ ++ PYWI+KNSWGA WGE+GY L RG NTCG++
Sbjct: 296 VGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGIT 355
Query: 336 NFVSTSII 343
F T+ +
Sbjct: 356 KFPLTARV 363
>sp|Q01958|CPP2_ENTHI CYSTEINE PROTEINASE 2 PRECURSOR
Length = 315
Score = 318 bits (807), Expect = 9e-87
Identities = 102/330 (30%), Positives = 160/330 (47%), Gaps = 37/330 (11%)
Query: 21 IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN-K 79
+ F + K NK ++ E L R IF N ++ N I K V+
Sbjct: 8 LAIASAIDFNTWASKNNKHFTAIEKLRRRAIFNMNAKFVDSFNKIG-----SFKLSVDGP 62
Query: 80 FADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQC 139
FA ++++E++ + + T++ YL+ + P + DWR G VTP+++Q QC
Sbjct: 63 FAAMTNEEYRTLLKSKRT---TEENGQVKYLNIQA----PESVDWRKEGKVTPIRDQAQC 115
Query: 140 GSCWSFSTTGNVEGQHFISQN---KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQP 196
GSC++F + +EG+ I + + LSE+++V C + + GCNGGL
Sbjct: 116 GSCYTFGSLAALEGRLLIEKGGDANTLDLSEEHMVQC--------TRDNGNNGCNGGLGS 167
Query: 197 NAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTG 256
N Y+YII++ G+ ES YPYT T C N + AKI+ +T +P+N +S G
Sbjct: 168 NVYDYIIEH-GVAKESDYPYTGSDST-CKTNVKSF-AKITGYTKVPRNNEAELKAALSQG 224
Query: 257 PLAIAADAVE--WQFYIGGVF-DIPCNPNS--LDHGILIVGYSAKNTIFRKNMPYWIVKN 311
+ ++ DA +Q Y G + D C N L+H + VGY + WIV+N
Sbjct: 225 LVDVSIDASSAKFQLYKSGAYTDTKCKNNYFALNHEVCAVGYGVVD-----GKECWIVRN 279
Query: 312 SWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
SWG WG++GYI + NTCGV+
Sbjct: 280 SWGTGWGDKGYINMVIEGNTCGVATDPLYP 309
>sp|P36185|ACP2_ENTHI CYSTEINE PROTEINASE ACP2 PRECURSOR
Length = 310
Score = 315 bits (799), Expect = 8e-86
Identities = 102/330 (30%), Positives = 158/330 (46%), Gaps = 32/330 (9%)
Query: 18 SRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGV 77
+ GI F + K NK ++ E L R IF N ++ N I K V
Sbjct: 1 AAGIRIASAIDFNTWASKNNKHFTAIEKLRRRAIFNMNAKFVDSFNKIG-----SFKLSV 55
Query: 78 N-KFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQ 136
+ FA ++++E++ + + T++ YL+ + P + DWR G VTP+++Q
Sbjct: 56 DGPFAAMTNEEYRTLLKSKRT---TEENGQVKYLNIQA----PESVDWRKEGKVTPLRDQ 108
Query: 137 GQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQP 196
QCGSC++F + +EG+ I + + N +D E M+ + + GCNGGL
Sbjct: 109 AQCGSCYTFGSLAALEGRLLIEKG-----GDANTLDLSEEHMQCT-RDNGNNGCNGGLGS 162
Query: 197 NAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTG 256
N Y+YII++ G+ ES YPYT T C N + KI+ +T +P+N +S G
Sbjct: 163 NVYDYIIEH-GVAKESDYPYTGSDST-CKTNVKSFR-KITGYTKVPRNNEAELKAALSQG 219
Query: 257 PLAIAADAVE--WQFYIGGVF-DIPCNPNS--LDHGILIVGYSAKNTIFRKNMPYWIVKN 311
L ++ D +Q Y G + D C N L+H + VGY + WIV+N
Sbjct: 220 LLDVSIDVSSAKFQLYKSGAYTDTKCKNNYFALNHEVCAVGYGVVD-----GKECWIVRN 274
Query: 312 SWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
SWG WG++GYI + NTCGV+
Sbjct: 275 SWGTSWGDKGYINMVIEGNTCGVATDPLYP 304
>sp|Q06964|CPP3_ENTHI CYSTEINE PROTEINASE 3 PRECURSOR (CYSTEINE PROTEINASE ACP3)
Length = 308
Score = 312 bits (790), Expect = 9e-85
Identities = 102/322 (31%), Positives = 157/322 (48%), Gaps = 37/322 (11%)
Query: 29 FLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN-KFADLSSDE 87
F + NK ++ E L R IF N + E N K K V+ FA ++++E
Sbjct: 9 FNTWAANNNKHFTAVEALRRRAIFNMNARFVAEFNK-----KGSFKLSVDGPFAAMTNEE 63
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
++ + + ++ YL+ + P + DWR +G VTP+++Q QCGSC++F +
Sbjct: 64 YRTLLKSKRTV---EENGKVTYLNIQA----PESVDWRAQGKVTPIRDQAQCGSCYTFGS 116
Query: 148 TGNVEGQHFISQN---KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK 204
+EG+ I + + LSE++LV C + + GCNGGL N Y+YII+
Sbjct: 117 LAALEGRLLIEKGGNANTLDLSEEHLVQC--------TRDNGNNGCNGGLGSNVYDYIIQ 168
Query: 205 NGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA 264
N G+ ES YPYT T C N AKI+ + +P+N +S G + ++ DA
Sbjct: 169 N-GVAKESDYPYTGTDST-CKTN-VKAFAKITGYNKVPRNNEAELKAALSQGLVDVSIDA 225
Query: 265 VE--WQFYIGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 319
+Q Y G + D C N +L+H + VGY + WIV+NSWG WG+
Sbjct: 226 SSAKFQLYKSGAYSDTKCKNNFFALNHEVCAVGYGVVD-----GKECWIVRNSWGTGWGD 280
Query: 320 QGYIYLRRGKNTCGVSNFVSTS 341
+GYI + NTCGV+
Sbjct: 281 KGYINMVIEGNTCGVATDPLYP 302
>sp|P36184|ACP1_ENTHI CYSTEINE PROTEINASE ACP1 PRECURSOR
Length = 308
Score = 309 bits (784), Expect = 5e-84
Identities = 109/348 (31%), Positives = 156/348 (44%), Gaps = 53/348 (15%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKI 59
M ++LFV V+ F ++ NK +++ EYL RF +F N +
Sbjct: 1 MFALILFVSLACANEVA-----------FKQWAATHNKVFANRAEYLYRFAVFLDNKKFV 49
Query: 60 EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
E A+ +N FAD++ +EF +L T ++P + + P
Sbjct: 50 E----------ANANTELNVFADMTHEEFIQTHLG-----MTYEVPETTSNVKAAVKAAP 94
Query: 120 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 179
+ DWR+ + P K+QGQCGSCW+F TT +EG+ KL S SEQ LVDCD
Sbjct: 95 ESVDWRS--IMNPAKDQGQCGSCWTFCTTAVLEGRVNKDLGKLYSFSEQQLVDCD----- 147
Query: 180 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFT 239
A D GC GG N+ +I +N G+ ES YPY A GT A ++
Sbjct: 148 -----ASDNGCEGGHPSNSLKFIQENNGLGLESDYPYKAVAGTC---KKVKNVATVTGSR 199
Query: 240 MIP-KNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVF--DIPCNPNSLDHGILIVGYS 294
+ +ET + I GP+A+ DA +Q Y G D C ++H + VGY
Sbjct: 200 RVTDGSETGLQTIIAENGPVAVGMDASRPSFQLYKKGTIYSDTKCRSRMMNHCVTAVGYG 259
Query: 295 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTS 341
N YWI++NSWG WG+ GY L R N CG+ +
Sbjct: 260 -----SNSNGKYWIIRNSWGTSWGDAGYFLLARDSNNMCGIGRDSNYP 302
>sp|P25326|CATS_BOVIN CATHEPSIN S
Length = 217
Score = 307 bits (778), Expect = 2e-83
Identities = 91/228 (39%), Positives = 129/228 (55%), Gaps = 17/228 (7%)
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
+P + DWR +G VT VK QG CGSCW+FS G +E Q + KLVSLS QNLVDC
Sbjct: 1 LPDSMDWREKGCVTEVKYQGACGSCWAFSAVGALEAQVKLKTGKLVSLSAQNLVDCST-- 58
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN 237
+ ++GCNGG A+ YII N GI +E+SYPY A G +C ++ N A S
Sbjct: 59 -----AKYGNKGCNGGFMTEAFQYIIDNNGIDSEASYPYKAMDG-KCQYDVKNRAATCSR 112
Query: 238 FTMIP-KNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGYS 294
+ +P +E + + + GP+++ DA + Y GV+ P +++HG+L+VGY
Sbjct: 113 YIELPFGSEEALKEAVANKGPVSVGIDASHSSFFLYKTGVYYDPSCTQNVNHGVLVVGYG 172
Query: 295 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTS 341
YW+VKNSWG +G+QGYI + R N CG++N+ S
Sbjct: 173 N-----LDGKDYWLVKNSWGLHFGDQGYIRMARNSGNHCGIANYPSYP 215
>sp|Q01957|CPP1_ENTHI CYSTEINE PROTEINASE 1 PRECURSOR
Length = 315
Score = 301 bits (763), Expect = 1e-81
Identities = 103/322 (31%), Positives = 155/322 (47%), Gaps = 37/322 (11%)
Query: 29 FLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN-KFADLSSDE 87
F + NK ++ E L R IF N + E N K V+ FA ++++E
Sbjct: 16 FNTWVANNNKHFTAVESLRRRAIFNMNARIVAENNRKE-----TFKLSVDGPFAAMTNEE 70
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFST 147
+ + + ++ YL+ + P A DWR +G VTP+++QG CGSC++F +
Sbjct: 71 YNSLLKLKRSG---EEKGEVRYLNIQA----PKAVDWRKKGKVTPIRDQGNCGSCYTFGS 123
Query: 148 TGNVEGQHFISQN---KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK 204
+EG+ I + + + LSE+++V C E + GCNGGL N YNYI++
Sbjct: 124 IAALEGRLLIEKGGDSETLDLSEEHMVQCTRE--------DGNNGCNGGLGSNVYNYIME 175
Query: 205 NGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA 264
N GI ES YPYT T C + AKI ++ + +N V +S G + ++ DA
Sbjct: 176 N-GIAKESDYPYTGSDST-CRSD-VKAFAKIKSYNRVARNNEVELKAAISQGLVDVSIDA 232
Query: 265 VE--WQFYIGGVF-DIPCNPNS--LDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 319
+Q Y G + D C N L+H + VGY + WIV+NSWG WGE
Sbjct: 233 SSVQFQLYKSGAYTDTQCKNNYFALNHEVCAVGYGVVD-----GKECWIVRNSWGTGWGE 287
Query: 320 QGYIYLRRGKNTCGVSNFVSTS 341
+GYI + NTCGV+
Sbjct: 288 KGYINMVIEGNTCGVATDPLYP 309
>sp|P25805|CYSP_PLAFA THROPHOZOITE CYSTEINE PROTEINASE PRECURSOR (TCP)
Length = 569
Score = 299 bits (758), Expect = 5e-81
Identities = 100/363 (27%), Positives = 161/363 (43%), Gaps = 62/363 (17%)
Query: 27 SQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
S+F +F + NK Y + +E + +FEIFK N I+ N +N A K VN+F+D S
Sbjct: 223 SKFFKFMKEHNKVYKNIDEQMRKFEIFKINYISIKNHNK--LNKNAMYKKKVNQFSDYSE 280
Query: 86 DEFKN--------------YYLNNKEAIFTDDLPVADYL------DDEFINSIPTAFDWR 125
+E K Y E D++ ++++ + + + +P D+R
Sbjct: 281 EELKEYFKTLLHVPNHMIEKYSKPFENHLKDNILISEFYTNGKRNEKDIFSKVPEILDYR 340
Query: 126 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEA 185
+G V K+QG CGSCW+F++ GN+E ++S SEQ +VDC +
Sbjct: 341 EKGIVHEPKDQGLCGSCWAFASVGNIESVFAKKNKNILSFSEQEVVDCSKD--------- 391
Query: 186 CDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNE 245
+ GC+GG ++ Y+++N + Y Y A+ C +S+ + E
Sbjct: 392 -NFGCDGGHPFYSFLYVLQN-ELCLGDEYKYKAKDDMFCLNYRCKRKVSLSSIGAV--KE 447
Query: 246 TVMAGYIVSTGPLAIAADA-VEWQFYIGGVFDIPCNPNSLDHGILIVGYS---------- 294
+ + GPL++ ++ Y GV++ C L+H +L+VGY
Sbjct: 448 NQLILALNEVGPLSVNVGVNNDFVAYSEGVYNGTC-SEELNHSVLLVGYGQVEKTKLNYN 506
Query: 295 ----AKNTIFRKNMP------YWIVKNSWGADWGEQGYIYLRRGKN----TCGVSNFVST 340
NT N P YWI+KNSW WGE G++ L R KN CG+ V
Sbjct: 507 NKIQTYNTKENSNQPDDNIIYYWIIKNSWSKKWGENGFMRLSRNKNGDNVFCGIGEEVFY 566
Query: 341 SII 343
I+
Sbjct: 567 PIL 569
>sp|P20721|CYSL_LYCES LOW-TEMPERATURE-INDUCED CYSTEINE PROTEINASE PRECURSOR
Length = 346
Score = 298 bits (756), Expect = 9e-81
Identities = 88/243 (36%), Positives = 130/243 (53%), Gaps = 21/243 (8%)
Query: 106 VADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL 165
+D + +S+P + DWR +G + VK+QG CGSCW+FS +E + I L+SL
Sbjct: 6 KSDRYLPKVGDSLPESIDWREKGVLVGVKDQGSCGSCWAFSAVAAMESINAIVTGNLISL 65
Query: 166 SEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCN 225
SEQ LVDCD + +EGC+GGL A+ ++IKNGGI TE YPY G
Sbjct: 66 SEQELVDCDR---------SYNEGCDGGLMDYAFEFVIKNGGIDTEEDYPYKERNGVCDQ 116
Query: 226 FNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNS 283
+ KI ++ +P N V+ P++IA +A ++Q Y G+F C +
Sbjct: 117 YRKNAKVVKIDSYEDVPVNNEKALQKAVAHQPVSIALEAGGRDFQHYKSGIFTGKCG-TA 175
Query: 284 LDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVSNFVS 339
+DHG++I GY +N M YWIV+NSWGA+ E GY+ ++R CG++ S
Sbjct: 176 VDHGVVIAGYGTEN-----GMDYWIVRNSWGANCRENGYLRVQRNVSSSSGLCGLAIEPS 230
Query: 340 TSI 342
+
Sbjct: 231 YPV 233
>sp|P43234|CATO_HUMAN CATHEPSIN O PRECURSOR
Length = 321
Score = 296 bits (750), Expect = 5e-80
Identities = 98/297 (32%), Positives = 151/297 (49%), Gaps = 20/297 (6%)
Query: 50 EIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADY 109
F+ +L + LN + + + +G+N+F+ L +EFK YL +K + F A+
Sbjct: 42 AAFRESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPR--YSAEV 99
Query: 110 LDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQN 169
S+P FDWR + VT V+NQ CG CW+FS G VE + I L LS Q
Sbjct: 100 HMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQ 159
Query: 170 LVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGG-IQTESSYPYTAETGTQCNFNS 228
++DC + GCNGG NA N++ K + +S YP+ A+ G F+
Sbjct: 160 VIDCS----------YNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYFSG 209
Query: 229 ANIGAKISNF--TMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDH 286
++ G I + E MA +++ GPL + DAV WQ Y+GG+ C+ +H
Sbjct: 210 SHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGIIQHHCSSGEANH 269
Query: 287 GILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
+LI G+ + PYWIV+NSWG+ WG GY +++ G N CG+++ VS+ +
Sbjct: 270 AVLITGFDKTG-----STPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV 321
>sp|P46102|CYSP_PLAVN CYSTEINE PROTEINASE PRECURSOR
Length = 506
Score = 291 bits (738), Expect = 1e-78
Identities = 108/360 (30%), Positives = 167/360 (46%), Gaps = 58/360 (16%)
Query: 27 SQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
S+F ++ + NKKY + +E L+RFE FK K ++ N + + VN+++D S
Sbjct: 160 SKFFKYMKENNKKYENMDEQLQRFENFKIRYMKTQKHNEMVGKNGLTYVQKVNQYSDFSK 219
Query: 86 DEFKNYYLNNKEAIFTDDL----PVADYLDDEFINSI-------PTAFDWRTRGAVTPVK 134
+EF NY+ P+ +L + + S+ P + D+R++ P K
Sbjct: 220 EEFDNYFKKLLSVPMDLKSKYIVPLKKHLANTNLISVDNKSKDFPDSRDYRSKFNFLPPK 279
Query: 135 NQGQCGSCWSFSTTGNVEGQHFISQNKL-VSLSEQNLVDCDHECMEYEGEEACDEGCNGG 193
+QG CGSCW+F+ GN E + +++++ +S SEQ +VDC E + GC+GG
Sbjct: 280 DQGNCGSCWAFAAIGNFEYLYVHTRHEMPISFSEQQMVDCSTE----------NYGCDGG 329
Query: 194 LQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIV 253
A+ Y+I N G+ YPY C ++ ++ + NE +M +
Sbjct: 330 NPFYAFLYMINN-GVCLGDEYPYKGHEDFFCLNYRCSLLGRVHFIGDVKPNELIM--ALN 386
Query: 254 STGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFR----------- 301
GP+ IA A ++ Y GGVFD CNP L+H +L+VGY
Sbjct: 387 YVGPVTIAVGASEDFVLYSGGVFDGECNP-ELNHSVLLVGYGQVKKSLAFEDSHSNVDSN 445
Query: 302 ---------KNMP------YWIVKNSWGADWGEQGYIYLRRGK----NTCGVSNFVSTSI 342
K YWIV+NSWG +WGE GYI ++R K CGV + V I
Sbjct: 446 LIKKYKENIKGDDDDDIIYYWIVRNSWGPNWGEGGYIRIKRNKAGDDGFCGVGSDVFFPI 505
>sp|P42666|CYSP_PLAVI CYSTEINE PROTEINASE PRECURSOR
Length = 583
Score = 278 bits (704), Expect = 1e-74
Identities = 100/383 (26%), Positives = 164/383 (42%), Gaps = 68/383 (17%)
Query: 11 VFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINH 69
V + + + S+F F +K+ + Y E +E+++ FK N KI++ N
Sbjct: 219 VSVAQIEGLFVNLKYASKFFNFMNKYKRSYKDINEQMEKYKNFKMNYLKIKKHNETNQM- 277
Query: 70 KADTKFGVNKFADLSSDEFKNYY---------LNNKEAIFTDDLPVADYLDDEFINS--- 117
K VN+F+D S +F++Y+ L K + + + +S
Sbjct: 278 ---YKMKVNQFSDYSKKDFESYFRKLVPIPDHLKKKYVVPFSSMNNGKGKNVVTSSSGAN 334
Query: 118 ----IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLV-SLSEQNLVD 172
+P D+R +G V K+QG CGSCW+F++ GNVE + NK + +LSEQ +VD
Sbjct: 335 LLADVPEILDYREKGIVHEPKDQGLCGSCWAFASVGNVECMYAKEHNKTILTLSEQEVVD 394
Query: 173 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG 232
C + GC+GG ++ Y I+N GI Y Y A C
Sbjct: 395 CSK----------LNFGCDGGHPFYSFIYAIEN-GICMGDDYKYKAMDNLFCLNYRCKNK 443
Query: 233 AKISNFTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIV 291
+S+ + +NE + + GP+++ ++ FY GG+F+ C L+H +L+V
Sbjct: 444 VTLSSVGGVKENE--LIRALNEVGPVSVNVGVTDDFSFYGGGIFNGTC-TEELNHSVLLV 500
Query: 292 GYS---------------AKNTIFRKN------------MPYWIVKNSWGADWGEQGYIY 324
GY + + +K YWI+KNSW WGE G++
Sbjct: 501 GYGQVQSSKIFQEKNAYDDASGVTKKGALSYPSKADDGIQYYWIIKNSWSKFWGENGFMR 560
Query: 325 LRRGKN----TCGVSNFVSTSII 343
+ R K CG+ V I+
Sbjct: 561 ISRNKEGDNVFCGIGVEVFYPIL 583
>sp|P16311|MMAL_DERFA MAJOR MITE FECAL ALLERGEN DER F 1 PRECURSOR (DER F I)
Length = 321
Score = 272 bits (688), Expect = 8e-73
Identities = 110/350 (31%), Positives = 150/350 (42%), Gaps = 46/350 (13%)
Query: 7 FVLAVFTVFVSSRGIP-PEEQSQFLEFQDKFNKKYSHEEYLE-RFEIFKSNLGKIEELNL 64
FVLA+ ++ V S P F EF+ FNK Y+ E E + F +L +E
Sbjct: 3 FVLAIASLLVLSTVYARPASIKTFEEFKKAFNKNYATVEEEEVARKNFLESLKYVEA--- 59
Query: 65 IAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFIN------SI 118
K +N +DLS DEFKN YL + EA + L L+ E ++
Sbjct: 60 --------NKGAINHLSDLSLDEFKNRYLMSAEAF--EQLKTQFDLNAETSACRINSVNV 109
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECM 178
P+ D R+ VTP++ QG CGSCW+FS E + +N + LSEQ LVDC
Sbjct: 110 PSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDC----- 164
Query: 179 EYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNF 238
A GC+G P YI +N G+ E SYPY A NS + G ISN+
Sbjct: 165 ------ASQHGCHGDTIPRGIEYIQQN-GVVEERSYPYVAREQRCRRPNSQHYG--ISNY 215
Query: 239 TMIPKNETVMAGYIVSTGPLAIAA-----DAVEWQFYIGG-VFDIPCNPNSLDHGILIVG 292
I + ++ AIA D +Q Y G + H + IVG
Sbjct: 216 CQIYPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVG 275
Query: 293 YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
Y + YWIV+NSW WG+ GY Y + G N + + I
Sbjct: 276 YG-----STQGDDYWIVRNSWDTTWGDSGYGYFQAGNNLMMIEQYPYVVI 320
>sp|P80884|ANAN_ANACO ANANAIN
Length = 216
Score = 271 bits (687), Expect = 1e-72
Identities = 93/229 (40%), Positives = 122/229 (52%), Gaps = 22/229 (9%)
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 177
+P + DWR GAVT VKNQG+CGSCW+F++ VE + I + LVSLSEQ ++DC
Sbjct: 1 VPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDC---- 56
Query: 178 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISN 237
A GC GG AY++II N G+ + + YPY A GT C N A I+
Sbjct: 57 -------AVSYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGT-CKTNGVPNSAYITR 108
Query: 238 FTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAK 296
+T + +N Y VS P+A A DA +Q Y GVF PC L+H I+I+GY
Sbjct: 109 YTYVQRNNERNMMYAVSNQPIAAALDASGNFQHYKRGVFTGPCG-TRLNHAIVIIGYGQD 167
Query: 297 NTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK----NTCGVSNFVSTS 341
+ +WIV+NSWGA WGE GYI L R CG++
Sbjct: 168 SA----GKKFWIVRNSWGAGWGEGGYIRLARDVSSSFGICGIAMDPLYP 212
>sp||CATL_CHICK_1 [Segment 1 of 2] CATHEPSIN L
Length = 176
Score = 264 bits (669), Expect = 1e-70
Identities = 86/183 (46%), Positives = 115/183 (61%), Gaps = 12/183 (6%)
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECM 178
P + DWR +G VTPVK+QGQCGSCW+FSTTG +EGQHF ++ KLVSLSEQNLVDC
Sbjct: 2 PRSVDWREKGYVTPVKDQGQCGSCWAFSTTGALEGQHFRTKGKLVSLSEQNLVDCS---- 57
Query: 179 EYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNF 238
++GCNGGL A+ Y+ NGGI +E SYPYTA+ C + + A + F
Sbjct: 58 ----RPEGNQGCNGGLMDQAFQYVQDNGGIDSEESYPYTAKDDEDCRYKAEYNAANDTGF 113
Query: 239 TMIPKN-ETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGILIVGYS 294
IP+ E + + S GP+++A DA +QFY G++ P C+ LDHG+L+VGY
Sbjct: 114 VDIPQGHERALMKAVASVGPVSVAIDAGHSSFQFYQSGIYYEPDCSSEDLDHGVLVVGYG 173
Query: 295 AKN 297
+
Sbjct: 174 FEG 176
>sp|P97821|CATC_MOUSE DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
(CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
Length = 462
Score = 262 bits (662), Expect = 9e-70
Identities = 86/317 (27%), Positives = 148/317 (46%), Gaps = 37/317 (11%)
Query: 43 EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTD 102
E Y ER + N ++ +N + K+ T ++ +S + +++
Sbjct: 161 ERYSERL--YTHNHNFVKAINTVQ---KSWTATAYKEYEKMSLRDLIRRSGHSQRIPRPK 215
Query: 103 DLPVADYLDDEFINSIPTAFDWRTR---GAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQ 159
P+ D + + +N +P ++DWR V+PV+NQ CGSC+SF++ G +E + I
Sbjct: 216 PAPMTDEIQQQILN-LPESWDWRNVQGVNYVSPVRNQESCGSCYSFASMGMLEARIRILT 274
Query: 160 NKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYT 217
N + LS Q +V C +GC+GG ++ G+ ES +PYT
Sbjct: 275 NNSQTPILSPQEVVSCSPYA----------QGCDGGFPYLIAGKYAQDFGVVEESCFPYT 324
Query: 218 AETGTQCNFNSANIGAKISNFTMIPK-----NETVMAGYIVSTGPLAIAADAVE-WQFYI 271
A+ + C + S++ + NE +M +V GP+A+A + + + Y
Sbjct: 325 AKD-SPCKPRENCLRYYSSDYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYH 383
Query: 272 GGVFDI-----PCNPNSL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
G++ P NP L +H +L+VGY + YWI+KNSWG++WGE GY +
Sbjct: 384 SGIYHHTGLSDPFNPFELTNHAVLLVGYGRDPVT---GIEYWIIKNSWGSNWGESGYFRI 440
Query: 326 RRGKNTCGVSNFVSTSI 342
RRG + C + + +I
Sbjct: 441 RRGTDECAIESIAVAAI 457
>sp|P25781|CYSP_THEAN CYSTEINE PROTEINASE PRECURSOR
Length = 441
Score = 259 bits (655), Expect = 6e-69
Identities = 105/343 (30%), Positives = 162/343 (46%), Gaps = 50/343 (14%)
Query: 28 QFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
+F F +K+ K + S ++ ++RF F+ N ++ +NKF+DLS +
Sbjct: 119 EFDAFVEKYKKVHRSFDQRVQRFLTFRKNYHIVKTHKPTEP-----YSLDLNKFSDLSDE 173
Query: 87 EFKNYY--------------------LNNKEAIFTDDLPVADYLDDEFINSIP--TAFDW 124
EFK Y +++K I+ L A +++ S+ +W
Sbjct: 174 EFKALYPVITPPKTYTSLSKHLEFKKMSHKNPIYISKLKKAKGIEEIKDLSLITGENLNW 233
Query: 125 RTRGAVTPVKNQG-QCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE 183
AV+P K+QG CGSCW+FS+ +VE + + +NK LSEQ LV+CD M
Sbjct: 234 ARTDAVSPTKDQGDHCGSCWAFSSIASVESLYRLYKNKSYFLSEQELVNCDKSSM----- 288
Query: 184 EACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPK 243
GC GGL A YI + G+ ES PYT + C + N I + +++
Sbjct: 289 -----GCAGGLPITALEYI-HSKGVSFESEVPYTGIV-SPCKPSIKN-KVFIDSISILKG 340
Query: 244 NETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKN 303
N+ V ++S + IA E + Y GG+F C L+H +L+VG +
Sbjct: 341 NDVVNKSLVISPTVVGIAVT-KELKLYSGGIFTGKCG-GELNHAVLLVGEGVDH---ETG 395
Query: 304 MPYWIVKNSWGADWGEQGYIYLRR---GKNTCGVSNFVSTSII 343
M YWI+KNSWG DWGE G++ L+R G + CG+ F I+
Sbjct: 396 MRYWIIKNSWGEDWGENGFLRLQRTKKGLDKCGILTFGLNPIL 438
>sp|P08176|MMAL_DERPT MAJOR MITE FECAL ALLERGEN DER P 1 PRECURSOR (DER P I)
Length = 320
Score = 255 bits (644), Expect = 1e-67
Identities = 105/356 (29%), Positives = 153/356 (42%), Gaps = 49/356 (13%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
MK++L + V +R P F E++ FNK Y+ E E + N +E
Sbjct: 1 MKIVLAIASLLALSAVYAR---PSSIKTFEEYKKAFNKSYATFEDE---EAARKN--FLE 52
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFI----- 115
+ + N +N +DLS DEFKN +L + EA + L L+ E
Sbjct: 53 SVKYVQSNGG-----AINHLSDLSLDEFKNRFLMSAEAF--EHLKTQFDLNAETNACSIN 105
Query: 116 NSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 175
+ P D R VTP++ QG CGSCW+FS E + +N+ + L+EQ LVDC
Sbjct: 106 GNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDC-- 163
Query: 176 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKI 235
A GC+G P YI NG +Q ES Y Y A + N+ G I
Sbjct: 164 ---------ASQHGCHGDTIPRGIEYIQHNGVVQ-ESYYRYVAREQSCRRPNAQRFG--I 211
Query: 236 SNFTMI-PKNETVMAGYIV-STGPLAIAA---DAVEWQFYIGGVF---DIPCNPNSLDHG 287
SN+ I P N + + + +A+ D ++ Y G D PN H
Sbjct: 212 SNYCQIYPPNVNKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNY--HA 269
Query: 288 ILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
+ IVGYS + + YWIV+NSW +WG+ GY Y + + + I+
Sbjct: 270 VNIVGYSN-----AQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPYVVIL 320
>sp|P14518|BROM_ANACO BROMELAIN, STEM
Length = 212
Score = 253 bits (640), Expect = 4e-67
Identities = 80/230 (34%), Positives = 114/230 (48%), Gaps = 27/230 (11%)
Query: 117 SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
++P + DWR GAVT VKNQ CG+CW+F+ VE + I + L LSEQ ++DC
Sbjct: 1 AVPQSIDWRDYGAVTSVKNQNPCGACWAFAAIATVESIYKIKKGILEPLSEQQVLDCAK- 59
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
GC GG + A+ +II N G+ + + YPY A GT C + A I+
Sbjct: 60 ----------GYGCKGGWEFRAFEFIISNKGVASGAIYPYKAAKGT-CKTDGVPNSAYIT 108
Query: 237 NFTMIPKNETVMAGYIVSTGPLAIAADA-VEWQFYIGGVFDIPCNPNSLDHGILIVGYSA 295
+ +P+N Y VS P+ +A DA +Q+Y GVF+ PC SL+H + +GY
Sbjct: 109 GYARVPRNNESSMMYAVSKQPITVAVDANANFQYYKSGVFNGPCG-TSLNHAVTAIGYGQ 167
Query: 296 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNTCGVSNFVSTS 341
+ I+ K WGA WGE GYI + R CG++
Sbjct: 168 DSIIYPK---------KWGAKWGEAGYIRMARDVSSSSGICGIAIDPLYP 208
>sp|P53634|CATC_HUMAN DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
(CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
Length = 463
Score = 251 bits (634), Expect = 2e-66
Identities = 86/318 (27%), Positives = 137/318 (43%), Gaps = 36/318 (11%)
Query: 41 SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIF 100
S E+Y R +K + ++ +N I + A T + L+ + + I
Sbjct: 159 SQEKYSNRL--YKYDHNFVKAINAIQKSWTATTYME---YETLTLGDMIRRSGGHSRKIP 213
Query: 101 TDDLPVADYLDDEFINSIPTAFDWRTRGA---VTPVKNQGQCGSCWSFSTTGNVEGQHFI 157
+ I +PT++DWR V+PV+NQ CGSC+SF++ G +E + I
Sbjct: 214 RPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRI 273
Query: 158 SQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYP 215
N + LS Q +V C +GC GG ++ G+ E+ +P
Sbjct: 274 LTNNSQTPILSPQEVVSCSQYA----------QGCEGGFPYLIAGKYAQDFGLVEEACFP 323
Query: 216 YTAETGTQCNFNSANIGAKISNFTMIPK-----NETVMAGYIVSTGPLAIAADAVE-WQF 269
YT + C S + + NE +M +V GP+A+A + + +
Sbjct: 324 YTGTD-SPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLH 382
Query: 270 YIGGVFDI-----PCNPNSL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 323
Y G++ P NP L +H +L+VGY + M YWIVKNSWG WGE GY
Sbjct: 383 YKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSAS---GMDYWIVKNSWGTGWGENGYF 439
Query: 324 YLRRGKNTCGVSNFVSTS 341
+RRG + C + + +
Sbjct: 440 RIRRGTDECAIESIAVAA 457
>sp|P80067|CATC_RAT DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
(CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
Length = 462
Score = 250 bits (631), Expect = 4e-66
Identities = 86/317 (27%), Positives = 145/317 (45%), Gaps = 37/317 (11%)
Query: 43 EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTD 102
E+Y ER + + ++ +N + + A T ++ LS + ++ +
Sbjct: 161 EKYSERL--YSHHHNFVKAINSVQKSWTATT---YRRYEKLSIRDLIRRSGHSGRILRPK 215
Query: 103 DLPVADYLDDEFINSIPTAFDWRTRGA---VTPVKNQGQCGSCWSFSTTGNVEGQHFISQ 159
P+ D + + + S+P ++DWR V+PV+NQ CGSC+SF++ G +E + I
Sbjct: 216 PAPITDEIQQQIL-SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASIGMLEARIRILT 274
Query: 160 NKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYT 217
N + LS Q +V C +GC+GG ++ G+ E+ +PYT
Sbjct: 275 NNSQTPILSPQEVVSCSPYA----------QGCDGGFPYLIAGKYAQDFGVVEENCFPYT 324
Query: 218 AETGTQCNFNSANIGAKISNFTMIPK-----NETVMAGYIVSTGPLAIAADAVE-WQFYI 271
A C + S + + NE +M +V GP+A+A + + + Y
Sbjct: 325 ATDAP-CKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYH 383
Query: 272 GGVFDI-----PCNPNSL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
G++ P NP L +H +L+VGY + YWIVKNSWG+ WGE GY +
Sbjct: 384 SGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVT---GLDYWIVKNSWGSQWGESGYFRI 440
Query: 326 RRGKNTCGVSNFVSTSI 342
RRG + C + + +I
Sbjct: 441 RRGTDECAIESIAMAAI 457
>sp|P22497|CYSP_THEPA CYSTEINE PROTEINASE PRECURSOR
Length = 439
Score = 243 bits (613), Expect = 5e-64
Identities = 98/342 (28%), Positives = 155/342 (44%), Gaps = 48/342 (14%)
Query: 24 EEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFAD 82
E +F EF K+N++++ + E L R F+SN +++E G+N+F+D
Sbjct: 119 EVYREFEEFNSKYNRRHATQQERLNRLVTFRSNYLEVKE-----QKGDEPYVKGINRFSD 173
Query: 83 LSSDEFKN---------------YYLNNKEAIFTDDLPVADYLDDEFINSIP----TAFD 123
L+ EF YYL + A T + L+ + + D
Sbjct: 174 LTEREFYKLFPVMKPPKATYSNGYYLLSHMANKTYLKNLKKALNTDEDVDLAKLTGENLD 233
Query: 124 WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE 183
WR +VT VK+Q CG CW+FST G+VEG + +K LS Q L+DCD
Sbjct: 234 WRRSSSVTSVKDQSNCGGCWAFSTVGSVEGYYMSHFDKSYELSVQELLDCD--------- 284
Query: 184 EACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPK 243
+ GC GGL +AY Y+ K G+ + P+ + +C+ A + ++ +
Sbjct: 285 -SFSNGCQGGLLESAYEYVRK-YGLVSAKDLPFV-DKARRCSVPKAK-KVSVPSYHVFKG 340
Query: 244 NETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRK 302
E + +++ P ++ E Y GVF C SL+H +++VG
Sbjct: 341 KE--VMTRSLTSSPCSVYLSVSPELAKYKSGVFTGECG-KSLNHAVVLVGEGYDEV---T 394
Query: 303 NMPYWIVKNSWGADWGEQGYIYLRR---GKNTCGVSNFVSTS 341
YW+V+NSWG DWGE GY+ L R G + CGV + ++
Sbjct: 395 KKRYWVVQNSWGTDWGENGYMRLERTNMGTDKCGVLDTSMSA 436
>sp|P07858|CATB_HUMAN CATHEPSIN B PRECURSOR (CATHEPSIN B1) (APP SECRETASE)
Length = 339
Score = 238 bits (602), Expect = 1e-62
Identities = 71/299 (23%), Positives = 114/299 (37%), Gaps = 58/299 (19%)
Query: 82 DLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQG 137
D+S YL F + +P +FD W + +++QG
Sbjct: 51 DMS-------YLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQG 103
Query: 138 QCGSCWSFSTTGNVEGQHFISQNKLVSL--SEQNLVDCDHECMEYEGEEACDEGCNGGLQ 195
CGSCW+F + + I N VS+ S ++L+ C C C +GCNGG
Sbjct: 104 SCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTC---C-----GSMCGDGCNGGYP 155
Query: 196 PNAYNYIIKNGGIQ----------------------TESSYPYTAETGT-QCN------F 226
A+N+ + G + S P T E T +C+ +
Sbjct: 156 AEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGY 215
Query: 227 NSANIGAKISNF--TMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNS 283
+ K + + +E + I GP+ A ++ Y GV+
Sbjct: 216 SPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMM 275
Query: 284 LDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
H I I+G+ +N PYW+V NSW DWG+ G+ + RG++ CG+ + V I
Sbjct: 276 GGHAIRILGWGVEN-----GTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGI 329
>sp|P00787|CATB_RAT CATHEPSIN B PRECURSOR (CATHEPSIN B1) (RSG-2)
Length = 339
Score = 236 bits (597), Expect = 4e-62
Identities = 69/289 (23%), Positives = 117/289 (39%), Gaps = 51/289 (17%)
Query: 92 YLNNKEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQCGSCWSFST 147
YL + + + ++P +FD W + +++QG CGSCW+F
Sbjct: 54 YLKKLCGTVLGGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGA 113
Query: 148 TGNVEGQHFISQNKLVSL--SEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKN 205
+ + I N V++ S ++L+ C C C +GCNGG A+N+ +
Sbjct: 114 VEAMSDRICIHTNGRVNVEVSAEDLLTC---C-----GIQCGDGCNGGYPSGAWNFWTRK 165
Query: 206 GGIQ----------------------TESSYPYTAETGT-QCN------FNSANIGAKIS 236
G + S P T E T +CN ++++ K
Sbjct: 166 GLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHY 225
Query: 237 NFTM--IPKNETVMAGYIVSTGPLAIAADA-VEWQFYIGGVFDIPCNPNSLDHGILIVGY 293
+T + +E + I GP+ A ++ Y GV+ H I I+G+
Sbjct: 226 GYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGW 285
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
+N + PYW+V NSW DWG+ G+ + RG+N CG+ + + I
Sbjct: 286 GIENGV-----PYWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAGI 329
>sp|P10605|CATB_MOUSE CATHEPSIN B PRECURSOR (CATHEPSIN B1)
Length = 339
Score = 233 bits (588), Expect = 4e-61
Identities = 67/289 (23%), Positives = 111/289 (38%), Gaps = 51/289 (17%)
Query: 92 YLNNKEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQCGSCWSFST 147
YL + + +P FD W + +++QG CGSCW+F
Sbjct: 54 YLKKLCGTVLGGPKLPGRVAFGEDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGA 113
Query: 148 TGNVEGQHFISQNKLVSL--SEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKN 205
+ + I N V++ S ++L+ C C C +GCNGG A+++ K
Sbjct: 114 VEAISDRTCIHTNGRVNVEVSAEDLLTC---C-----GIQCGDGCNGGYPSGAWSFWTKK 165
Query: 206 GGIQ----------------------TESSYPYTAETGT-QCN------FNSANIGAKIS 236
G + S P T E T +CN ++ + K
Sbjct: 166 GLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPPCTGEGDTPRCNKSCEAGYSPSYKEDKHF 225
Query: 237 NFTM--IPKNETVMAGYIVSTGPLAIAADA-VEWQFYIGGVFDIPCNPNSLDHGILIVGY 293
+T + + + I GP+ A ++ Y GV+ H I I+G+
Sbjct: 226 GYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGW 285
Query: 294 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
+N + PYW+ NSW DWG+ G+ + RG+N CG+ + + I
Sbjct: 286 GVENGV-----PYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGI 329
>sp|P43509|CPR5_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 5 PRECURSOR
Length = 344
Score = 232 bits (586), Expect = 8e-61
Identities = 68/280 (24%), Positives = 114/280 (40%), Gaps = 53/280 (18%)
Query: 105 PVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN 160
D + E ++IP FD W ++ +++Q CGSCW+F+ + + I+ N
Sbjct: 69 KDEDIVATEVSDAIPDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASN 128
Query: 161 KLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTES------ 212
V+ LS ++L+ C G +C GC GG A+ + +K+G + S
Sbjct: 129 GAVNTLLSSEDLLSC------CTGMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFG 182
Query: 213 SYPYTA-------------------ETGTQC--------NFNSANIGAKISNFTM--IPK 243
PY+ E +C N+ + + K T + K
Sbjct: 183 CKPYSIAPCGETVNGVKWPACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGK 242
Query: 244 NETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRK 302
+ I++ GP+ +A ++ Y GV+ + H + I+G+ N
Sbjct: 243 KVEQIQTEILTNGPIEVAFTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDN----- 297
Query: 303 NMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
PYW+V NSW WGE+GY + RG N CG+ + I
Sbjct: 298 GTPYWLVANSWNVAWGEKGYFRIIRGLNECGIEHSAVAGI 337
>sp|P07688|CATB_BOVIN CATHEPSIN B PRECURSOR
Length = 335
Score = 232 bits (586), Expect = 8e-61
Identities = 66/263 (25%), Positives = 108/263 (40%), Gaps = 51/263 (19%)
Query: 118 IPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL--SEQNLV 171
+P +FD W + +++QG CGSCW+F + + I N V++ S ++++
Sbjct: 80 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 139
Query: 172 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ---------------------- 209
C GE C +GCNGG A+N+ K G +
Sbjct: 140 TC------CGGE--CGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHV 191
Query: 210 TESSYPYTAETGT-QCN------FNSANIGAKISN--FTMIPKNETVMAGYIVSTGPLAI 260
S P T E T +CN ++ + K + NE + I GP+
Sbjct: 192 NGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEG 251
Query: 261 AADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 319
A ++ Y GV+ H I I+G+ +N PYW+V NSW DWG+
Sbjct: 252 AFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVEN-----GTPYWLVGNSWNTDWGD 306
Query: 320 QGYIYLRRGKNTCGVSNFVSTSI 342
G+ + RG++ CG+ + + +
Sbjct: 307 NGFFKILRGQDHCGIESEIVAGM 329
>sp|P43233|CATB_CHICK CATHEPSIN B PRECURSOR (CATHEPSIN B1)
Length = 340
Score = 232 bits (585), Expect = 1e-60
Identities = 72/323 (22%), Positives = 122/323 (37%), Gaps = 62/323 (19%)
Query: 59 IEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSI 118
+ +N + +A F D+S Y+ F + +D +
Sbjct: 31 VNHINKLNTTGRAGHNF---HNTDMS-------YVKKLCGTFLGGPKAPERVDFAEDMDL 80
Query: 119 PTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVD 172
P FD W ++ +++QG CGSCW+F + + + N VS +S ++L+
Sbjct: 81 PDTFDTRKQWPNCPTISEIRDQGSCGSCWAFGAVEAISDRICVHTNAKVSVEVSAEDLLS 140
Query: 173 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGI----------------------QT 210
C C C GCNGG A+ Y + G +
Sbjct: 141 C---C-----GFECGMGCNGGYPSGAWRYWTERGLVSGGLYDSHVGCRAYTIPPCEHHVN 192
Query: 211 ESSYPYTAETGT--QCN------FNSANIGAKISNFTM--IPKNETVMAGYIVSTGPLAI 260
S P T E G +C+ ++ + K T +P++E + I GP+
Sbjct: 193 GSRPPCTGEGGETPRCSRHCEPGYSPSYKEDKHYGITSYGVPRSEKEIMAEIYKNGPVEG 252
Query: 261 AADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 319
A ++ Y GV+ H I I+G+ +N PYW+ NSW DWG
Sbjct: 253 AFIVYEDFLMYKSGVYQHVSGEQVGGHAIRILGWGVEN-----GTPYWLAANSWNTDWGI 307
Query: 320 QGYIYLRRGKNTCGVSNFVSTSI 342
G+ + RG++ CG+ + + +
Sbjct: 308 TGFFKILRGEDHCGIESEIVAGV 330
>sp|Q26563|CATC_SCHMA CATHEPSIN C PRECURSOR
Length = 454
Score = 231 bits (584), Expect = 1e-60
Identities = 80/281 (28%), Positives = 124/281 (43%), Gaps = 38/281 (13%)
Query: 81 ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFI---NSIPTAFDWRT-----RGAVTP 132
+ + DE +N K + + E I ++P FDW + R VTP
Sbjct: 178 SKYTIDELRNRAGGVKSMVTRPSVLNRKTPSKELISLTGNLPLEFDWTSPPDGSRSPVTP 237
Query: 133 VKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLVDCDHECMEYEGEEACDEGC 190
++NQG CGSC++ + +E + + N + LS Q +VDC EGC
Sbjct: 238 IRNQGICGSCYASPSAAALEARIRLVSNFSEQPILSPQTVVDCSPY----------SEGC 287
Query: 191 NGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPK-----NE 245
NGG ++ G+ + PYT E +C + ++++ I NE
Sbjct: 288 NGGFPFLIAGKYGEDFGLPQKIVIPYTGEDTGKCTVSKNCTRYYTTDYSYIGGYYGATNE 347
Query: 246 TVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPC--------NPNSL-DHGILIVGYSA 295
+M ++S GP + + ++QFY G++ NP L +H +L+VGY
Sbjct: 348 KLMQLELISNGPFPVGFEVYEDFQFYKEGIYHHTTVQTDHYNFNPFELTNHAVLLVGYGV 407
Query: 296 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 336
PYW VKNSWG +WGEQGY + RG + CGV +
Sbjct: 408 DKLS---GEPYWKVKNSWGVEWGEQGYFRILRGTDECGVES 445
>sp|P25807|CYS1_CAEEL GUT-SPECIFIC CYSTEINE PROTEINASE PRECURSOR
Length = 329
Score = 231 bits (584), Expect = 1e-60
Identities = 69/290 (23%), Positives = 114/290 (38%), Gaps = 46/290 (15%)
Query: 83 LSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQ 138
++ +E K ++ K A D + + + S+P FD W ++ +++Q
Sbjct: 51 ITEEEMKFKLMDGKYAAAHSD-EIRATEQEVVLASVPATFDSRTQWSECKSIKLIRDQAT 109
Query: 139 CGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQP 196
CGSCW+F + + I +S +L+ C C +C GC GG
Sbjct: 110 CGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLLSC---C-----GSSCGNGCEGGYPI 161
Query: 197 NAYNYIIKNGGIQTESSY------PYTAETGTQ--------------CNFNSANIGAKIS 236
A + + G+ T Y PY T C + AK
Sbjct: 162 QALRWW-DSKGVVTGGDYHGAGCKPYPIAPCTSGNCPESKTPSCSMSCQSGYSTAYAKDK 220
Query: 237 NFTM----IPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIV 291
+F + +PKN + I + GP+ A ++ Y GV+ H I I+
Sbjct: 221 HFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDFYKYKSGVYKHTAGKYLGGHAIKII 280
Query: 292 GYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
G+ ++ PYW+V NSWG +WGE G+ + RG + CG+ + V
Sbjct: 281 GWGTES-----GSPYWLVANSWGVNWGESGFFKIYRGDDQCGIESAVVAG 325
>sp|P43508|CPR4_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 4 PRECURSOR
Length = 335
Score = 231 bits (583), Expect = 2e-60
Identities = 78/304 (25%), Positives = 126/304 (40%), Gaps = 60/304 (19%)
Query: 82 DLSSDEFKNYYLNNK-EAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQ 136
D++ ++ K + + A T D+ V + +E ++IP FD W ++ +++Q
Sbjct: 46 DITIEQVKKRLMRTEFVAPHTPDVEVVKHDINE--DTIPATFDARTQWPNCMSINNIRDQ 103
Query: 137 GQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGL 194
CGSCW+F+ + I+ N V+ LS ++++ C C C GC GG
Sbjct: 104 SDCGSCWAFAAAEAASDRFCIASNGAVNTLLSAEDVLSC---CSN------CGYGCEGGY 154
Query: 195 QPNAYNYIIKNGGIQTESSY-------PYT-------------------AETGTQC---- 224
NA+ Y++K+G T SY PY+ C
Sbjct: 155 PINAWKYLVKSG-FCTGGSYEAQFGCKPYSLAPCGETVGNVTWPSCPDDGYDTPACVNKC 213
Query: 225 ---NFNSANIGAKISNFTM--IPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIP 278
N+N A K T + K + + I++ GP+ A ++ Y GV+
Sbjct: 214 TNKNYNVAYTADKHFGSTAYAVGKKVSQIQAEIIAHGPVEAAFTVYEDFYQYKTGVYVHT 273
Query: 279 CNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFV 338
H I I+G+ N PYW+V NSW +WGE GY + RG N CG+ + V
Sbjct: 274 TGQELGGHAIRILGWGTDN-----GTPYWLVANSWNVNWGENGYFRIIRGTNECGIEHAV 328
Query: 339 STSI 342
+
Sbjct: 329 VGGV 332
>sp|P43510|CPR6_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6 PRECURSOR
Length = 379
Score = 225 bits (569), Expect = 8e-59
Identities = 83/388 (21%), Positives = 143/388 (36%), Gaps = 78/388 (20%)
Query: 1 MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
MK +L V + + DK+ + E E L +
Sbjct: 1 MKTLLFLSCIVVAAYCAC-------NDNLESVLDKYRNREIDSEAAE--------LDGDD 45
Query: 61 ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSI-- 118
++ + N T +F+ + + K + + +L +
Sbjct: 46 LIDYVNENQNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLSKTKDLDLDI 105
Query: 119 PTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNK--LVSLSEQNLVD 172
P +FD W ++ +++Q CGSCW+F + + I+ + V+LS +L+
Sbjct: 106 PESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLS 165
Query: 173 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ------CNF 226
C +C GCNGG A+ Y +K+G I T S+Y TA G + C
Sbjct: 166 CCK---------SCGFGCNGGDPLAAWRYWVKDG-IVTGSNY--TANNGCKPYPFPPCEH 213
Query: 227 NSANIGA----------------KISNFTMIPKNE---------------TVMAGYIVST 255
+S +S++T +E + +++
Sbjct: 214 HSKKTHFDPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTH 273
Query: 256 GPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWG 314
GPL IA + ++ Y GGV+ H + ++G+ + I PYW V NSW
Sbjct: 274 GPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGI-----PYWTVANSWN 328
Query: 315 ADWGEQGYIYLRRGKNTCGVSNFVSTSI 342
DWGE G+ + RG + CG+ + V I
Sbjct: 329 TDWGEDGFFRILRGVDECGIESGVVGGI 356
>sp|P43157|CYSP_SCHJA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECURSOR (ANTIGEN SJ31)
Length = 342
Score = 222 bits (559), Expect = 1e-57
Identities = 69/299 (23%), Positives = 114/299 (38%), Gaps = 53/299 (17%)
Query: 84 SSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQC 139
S D+ + KE + IP+ FD W +++ +++Q +C
Sbjct: 56 SLDDARILMGARKEDAEMKRNRRPTVDHHDLNVEIPSQFDSRKKWPHCKSISQIRDQSRC 115
Query: 140 GSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPN 197
GSCW+F + + I S LS +L+ C C + C +GC GG
Sbjct: 116 GSCWAFGAVEAMTDRICIQSGGGQSAELSALDLISC---CKD------CGDGCQGGFPGV 166
Query: 198 AYNYIIKNGGIQTESS--------YPY----------------TAETGTQCN------FN 227
A++Y +K G + S YP+ QC +
Sbjct: 167 AWDYWVKRGIVTGGSKENHTGCQPYPFPKCEHHTKGKYPACGTKIYKTPQCKQTCQKGYK 226
Query: 228 SANIGAKISN--FTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSL 284
+ K + NE V+ I+ GP+ A D ++ Y G++
Sbjct: 227 TPYEQDKHYGDESYNVQNNEKVIQRDIMMYGPVEAAFDVYEDFLNYKSGIYRHVTGSIVG 286
Query: 285 DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
H I I+G+ + K PYW++ NSW DWGE+G + RG++ C + + V +I
Sbjct: 287 GHAIRIIGWGVE-----KRTPYWLIANSWNEDWGEKGLFRMVRGRDECSIESDVVAGLI 340
>sp|P25792|CYSP_SCHMA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECURSOR (ANTIGEN SM31)
Length = 340
Score = 216 bits (545), Expect = 5e-56
Identities = 67/303 (22%), Positives = 117/303 (38%), Gaps = 55/303 (18%)
Query: 78 NKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPV 133
N+F L + + + P D+ +++ IP+ FD W ++ +
Sbjct: 51 NRFHSLDDARIQMGARREEPDLRRKRRPTVDH--NDWNVEIPSNFDSRKKWPGCKSIATI 108
Query: 134 KNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLVDCDHECMEYEGEEACDEGCN 191
++Q +CGSCWSF + + I + V LS +L+ C C E+C GC
Sbjct: 109 RDQSRCGSCWSFGAVEAMSDRSCIQSGGKQNVELSAVDLLTC---C------ESCGLGCE 159
Query: 192 GGLQPNAYNYIIKNGGIQTESS--------YPY----------------------TAETG 221
GG+ A++Y +K G + S YP+ +
Sbjct: 160 GGILGPAWDYWVKEGIVTASSKENHTGCEPYPFPKCEHHTKGKYPPCGSKIYNTPRCKQT 219
Query: 222 TQCNFNSANIGAKISN--FTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIP 278
Q + + K + +E + I+ GP+ + ++ Y G++
Sbjct: 220 CQRKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEASFTVYEDFLNYKSGIYKHI 279
Query: 279 CNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFV 338
H I I+G+ +N PYW++ NSW DWGE GY + RG++ C + + V
Sbjct: 280 TGEALGGHAIRIIGWGVEN-----KTPYWLIANSWNEDWGENGYFRIVRGRDECSIESEV 334
Query: 339 STS 341
Sbjct: 335 IAG 337
>sp|P25802|CYS1_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PRECURSOR
Length = 341
Score = 213 bits (537), Expect = 4e-55
Identities = 64/297 (21%), Positives = 110/297 (36%), Gaps = 56/297 (18%)
Query: 88 FKNYYLNNKEAIFTD--DLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQCGS 141
FK ++ K + D V D +E + IP ++D W ++ + +Q CGS
Sbjct: 59 FKQRLMDLKYIDQNNIPDEEVEDEELEENNDDIPESYDPRIQWANCSSLFHIPDQANCGS 118
Query: 142 CWSFSTTGNVEGQHFISQN--KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 199
CW+ S+ + + I+ K V +S Q++V C C C +GC GG +A+
Sbjct: 119 CWAVSSAAAMSDRICIASKGAKQVLISAQDVVSC---CTW------CGDGCEGGWPISAF 169
Query: 200 NYIIKNGGIQ------TESSYPYTAETGTQCNFNSANIGAKI------------------ 235
+ G + S PY + N G +
Sbjct: 170 RFHADEGVVTGGDYNTKGSCRPYEIHPCGH-HGNETYYGECVGMADTPRCKRRCLLGYPK 228
Query: 236 --------SNFTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDH 286
+ + + I+ GP+ ++ Y G++ + H
Sbjct: 229 SYPSDRYYKKAYQLKNSVKAIQKDIMKNGPVVATYTVYEDFAHYRSGIYKHKAGRKTGLH 288
Query: 287 GILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
+ ++G+ + K PYWIV NSW DWGE G+ + RG N CG ++ +
Sbjct: 289 AVKVIGWGEE-----KGTPYWIVANSWHDDWGENGFFRMHRGSNDCGFEERMAAGSV 340
>sp|P25793|CYS2_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 2 PRECURSOR
Length = 342
Score = 212 bits (534), Expect = 1e-54
Identities = 64/302 (21%), Positives = 119/302 (39%), Gaps = 56/302 (18%)
Query: 81 ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQ 136
+D + D F+ ++ K +L V + D E IP ++D W+ +++Q
Sbjct: 53 SDPTPD-FEQKIMSIKYKHQKLNLMVKEDPDPEVD--IPPSYDPRDVWKNCTTFY-IRDQ 108
Query: 137 GQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGL 194
CGSCW+ ST + + I+ K V++S +++ C C C +GC GG
Sbjct: 109 ANCGSCWAVSTAAAISDRICIASKAEKQVNISATDIMTC---C-----RPQCGDGCEGGW 160
Query: 195 QPNAYNYIIKNGGIQTES------SYPYTAET----GTQCNFNSANIGAKI--------- 235
A+ Y I +G + PY G + A
Sbjct: 161 PIEAWKYFIYDGVVSGGEYLTKDVCRPYPIHPCGHHGNDTYYGECRGTAPTPPCKRKCRP 220
Query: 236 -------------SNFTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNP 281
+ ++ ++ + I+ GP+ + +++ Y G++
Sbjct: 221 GVRKMYRIDKRYGKDAYIVKQSVKAIQSEILKNGPVVASFAVYEDFRHYKSGIYKHTAGE 280
Query: 282 NSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 341
H + ++G+ +N N +W++ NSW DWGE+GY + RG N CG+ ++
Sbjct: 281 LRGYHAVKMIGWGNEN-----NTDFWLIANSWHNDWGEKGYFRIVRGSNDCGIEGTIAAG 335
Query: 342 II 343
I+
Sbjct: 336 IV 337
>sp|P19092|CYS1_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PRECURSOR
Length = 342
Score = 208 bits (523), Expect = 2e-53
Identities = 62/295 (21%), Positives = 115/295 (38%), Gaps = 55/295 (18%)
Query: 88 FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD----WRTRGAVTPVKNQGQCGSCW 143
F+ ++ K +L V + D E IP ++D W+ +++Q CGSCW
Sbjct: 59 FEQKIMDIKYKHQKLNLMVKEDPDPEVD--IPPSYDPRDVWKNCTTFY-IRDQANCGSCW 115
Query: 144 SFSTTGNVEGQHFISQN--KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNY 201
+ ST + + I+ K V++S +++ C C C +GC GG A+ Y
Sbjct: 116 AVSTAAAISDRICIASKAEKQVNISATDIMTC---C-----RPQCGDGCEGGWPIEAWKY 167
Query: 202 IIKNGGIQTES------SYPYTAET----GTQCNFNSANIGAKI---------------- 235
I +G + PY G + A
Sbjct: 168 FIYDGVVSGGEYLTKDVCRPYPIHPCGHHGNDTYYGECRGTAPTPPCKRKCRPGVRKMYR 227
Query: 236 ------SNFTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGI 288
+ ++ ++ + I+ GP+ + +++ Y G++ H +
Sbjct: 228 IDKRYGKDAYIVKQSVKAIQSEILRNGPVVASFAVYEDFRHYKSGIYKHTAGELRGYHAV 287
Query: 289 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343
++G+ +N N +W++ NSW DWGE+GY + RG N CG+ ++ I+
Sbjct: 288 KMIGWGNEN-----NTDFWLIANSWHNDWGEKGYFRIIRGTNDCGIEGTIAAGIV 337
>sp|P43507|CPR3_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3 PRECURSOR
Length = 370
Score = 204 bits (513), Expect = 3e-52
Identities = 61/265 (23%), Positives = 99/265 (37%), Gaps = 49/265 (18%)
Query: 112 DEFINSIPTAFD----WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVS--L 165
+ +P FD W + ++NQ CGSCW+F + + I N +
Sbjct: 86 EIVPEPLPDTFDAREKWPDCNTIKLIRNQATCGSCWAFGAAEVISDRVCIQSNGTQQPVI 145
Query: 166 SEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSY------PYTAE 219
S ++++ C C C GC GG A + +G + T Y PY+
Sbjct: 146 SVEDILSC---C-----GTTCGYGCKGGYSIEALRFWASSGAV-TGGDYGGHGCMPYSFA 196
Query: 220 TGTQ---------CNF------------NSANIGAKISNFTMIPKNETVMAGYIVSTGPL 258
T+ C + GA T K+ T + I GP+
Sbjct: 197 PCTKNCPESTTPSCKTTCQSSYKTEEYKKDKHYGASAYKVTT-TKSVTEIQTEIYHYGPV 255
Query: 259 AIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 317
+ ++ Y GV+ H + I+G+ +N + YW++ NSWG +
Sbjct: 256 EASYKVYEDFYHYKSGVYHYTSGKLVGGHAVKIIGWGVENGV-----DYWLIANSWGTSF 310
Query: 318 GEQGYIYLRRGKNTCGVSNFVSTSI 342
GE+G+ +RRG N C + V I
Sbjct: 311 GEKGFFKIRRGTNECQIEGNVVAGI 335
>sp|P25780|EUM1_EURMA MITE GROUP I ALLERGEN EUR M 1 (EUR M I)
Length = 211
Score = 201 bits (507), Expect = 1e-51
Identities = 69/220 (31%), Positives = 99/220 (44%), Gaps = 25/220 (11%)
Query: 117 SIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176
S+P+ D R+ VTP++ QG CGSCW+FS + E + +N + L+EQ LVDC
Sbjct: 10 SLPSELDLRSLRTVTPIRMQGGCGSCWAFSGVASTESAYLAYRNMSLDLAEQELVDC--- 66
Query: 177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKIS 236
A GC+G P YI +NG +Q E YPY A + N+ G K
Sbjct: 67 --------ASQNGCHGDTIPRGIEYIQQNGVVQ-EHYYPYVAREQSCHRPNAQRYGLK-- 115
Query: 237 NFTMIPKNETVMAGYIVSTGPLAIAA-----DAVEWQFYIGGVFDIPCNPNSLD-HGILI 290
N+ I ++ ++ A+A D ++ Y G N + H + I
Sbjct: 116 NYCQISPPDSNKIRQALTQTHTAVAVIIGIKDLNAFRHYDGRTIMQHDNGYQPNYHAVNI 175
Query: 291 VGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKN 330
VGY + + YWIV+NSW WG+ GY Y N
Sbjct: 176 VGYGN-----TQGVDYWIVRNSWDTTWGDNGYGYFAANIN 210
>sp|P25773|CATL_FELCA CATHEPSIN L (PROGESTERONE-DEPENDENT PROTEIN) (PDP)
Length = 139
Score = 185 bits (464), Expect = 2e-46
Identities = 55/141 (39%), Positives = 84/141 (59%), Gaps = 5/141 (3%)
Query: 192 GGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGY 251
GGL +A+ Y+ NGG+ +E SYPY A+ G C + N A ++++ IP E +
Sbjct: 1 GGLIDDAFQYVKDNGGLDSEESYPYHAQ-GDSCKYRPENSVANVTDYWDIPSKENELMIT 59
Query: 252 IVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGILIVGYSAKNTIFRKNMPYWI 308
+ + GP++ A DA ++FY G++ P C+ +DHG+L+VGY A T +N YWI
Sbjct: 60 LAAVGPISAAIDASLDTFRFYKEGIYYDPSCSSEDVDHGVLVVGYGADGT-ETENKKYWI 118
Query: 309 VKNSWGADWGEQGYIYLRRGK 329
+KNSWG DWG GYI + + +
Sbjct: 119 IKNSWGTDWGMDGYIKMAKDR 139
>sp|Q23894|CYS3_DICDI CYSTEINE PROTEINASE 3 (CYSTEINE PROTEINASE II)
Length = 151
Score = 158 bits (395), Expect = 2e-38
Identities = 61/158 (38%), Positives = 86/158 (53%), Gaps = 17/158 (10%)
Query: 41 SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIF 100
+H+E++ R+E FK N+ + N + + T G+N+ ADLS++E++ YL + I
Sbjct: 1 THKEFMPRYEEFKKNMDYVHNWN----SKGSKTVLGLNQHADLSNEEYRLNYLGTRAHIK 56
Query: 101 TDDLPVAD---YLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFI 157
+ + L+ P DWR + AVTPVK+QGQCGSC STTG+VEG I
Sbjct: 57 LNGYHKRNLGLRLNRPHFKQ-PLNVDWREKDAVTPVKDQGQCGSC-IISTTGSVEGVTAI 114
Query: 158 SQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQ 195
KLVSLSEQN++ +EGCNGGL
Sbjct: 115 KTGKLVSLSEQNILRLSSSF--------GNEGCNGGLM 144
>sp|P13823|SERA_PLAFG SERINE-REPEAT ANTIGEN PROTEIN PRECURSOR (P126) (111 KD ANTIGEN)
Length = 989
Score = 157 bits (393), Expect = 3e-38
Identities = 60/255 (23%), Positives = 101/255 (39%), Gaps = 46/255 (18%)
Query: 123 DWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEG 182
D + V++QG C + W F++ ++E + + +S + +C Y+G
Sbjct: 569 DENNCISNLQVEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANC------YKG 622
Query: 183 EEACDEGCNGGLQPNAYNYIIKNGG-IQTESSYPYT-AETGTQCN--------------- 225
E + C+ G P + II++ G + ES+YPY + G QC
Sbjct: 623 EHK--DRCDEGSSPMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKI 680
Query: 226 -----------------FNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQ 268
+ S + F I K E + G +++ I A+ V
Sbjct: 681 LHNKNEPNSLDGKGYTAYESERFHDNMDAFVKIIKTEVMNKGSVIAY----IKAENVMGY 736
Query: 269 FYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG 328
+ G C ++ DH + IVGY + YWIV+NSWG WG++GY +
Sbjct: 737 EFSGKKVQNLCGDDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMY 796
Query: 329 KNTCGVSNFVSTSII 343
T NF+ + +I
Sbjct: 797 GPTHCHFNFIHSVVI 811
>sp|Q06544|CYS3_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3
Length = 174
Score = 139 bits (348), Expect = 6e-33
Identities = 31/130 (23%), Positives = 53/130 (39%), Gaps = 8/130 (6%)
Query: 217 TAETGTQCNFNSANIGAKISN--FTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGG 273
+ Q + A K +P N + I+ GP+ ++ Y G
Sbjct: 50 KCQKTCQRGYLKAYKEDKHFGKSAYRLPNNVKAIQRDIMKNGPVVAGFIVYEDFAHYKSG 109
Query: 274 VFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCG 333
++ + H + I+G+ + K PYW++ NSW DWGE+G+ + RG N C
Sbjct: 110 IYKHTAGRMTGGHAVKIIGWGKE-----KGTPYWLIANSWHDDWGEKGFYRMIRGINNCR 164
Query: 334 VSNFVSTSII 343
+ V I+
Sbjct: 165 IEEMVFAGIV 174
>sp|P05993|PAP5_CARPA CYSTEINE PROTEINASE (CLONE PLBPC13)
Length = 96
Score = 131 bits (327), Expect = 2e-30
Identities = 43/87 (49%), Positives = 55/87 (62%), Gaps = 2/87 (2%)
Query: 256 GPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN--TIFRKNMPYWIVKNSW 313
GPLA+A +A Q YIGGV L+HG+L+VGY + I K PYW++KNSW
Sbjct: 1 GPLAVAINAAYMQTYIGGVSCPYICSRRLNHGVLLVGYGSAGYAPIRLKEKPYWVIKNSW 60
Query: 314 GADWGEQGYIYLRRGKNTCGVSNFVST 340
G +WGE GY + RG+N CGV + VST
Sbjct: 61 GENWGENGYYKICRGRNICGVDSMVST 87
>sp|P12399|CT2A_MOUSE CTLA-2-ALPHA PROTEIN PRECURSOR
Length = 136
Score = 98.2 bits (241), Expect = 2e-20
Identities = 32/131 (24%), Positives = 53/131 (40%), Gaps = 14/131 (10%)
Query: 8 VLAVFTVFVSSRGIPPE--EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLI 65
L + + + S PP+ +++ E++ KF K Y+ E R +++ N KIE N
Sbjct: 16 FLLILCLGMMSAAPPPDPSLDNEWKEWKTKFAKAYNLNEERHRRLVWEENKKKIEAHNAD 75
Query: 66 AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWR 125
K G+N+F+DL+ +EFK N E +P D
Sbjct: 76 YEQGKTSFYMGLNQFSDLTPEEFKTNCYGNSL------------NRGEMAPDLPEYEDLG 123
Query: 126 TRGAVTPVKNQ 136
+TP + Q
Sbjct: 124 KNSYLTPGRAQ 134
>sp|P12400|CT2B_MOUSE CTLA-2-BETA PROTEIN PRECURSOR
Length = 141
Score = 95.9 bits (235), Expect = 1e-19
Identities = 29/133 (21%), Positives = 54/133 (39%), Gaps = 13/133 (9%)
Query: 4 ILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELN 63
+ L +L + + + P +++ E++ F K YS +E R +++ N KIE N
Sbjct: 20 VFLLILCLGMMSAAPS-PDPSLDNEWKEWKTTFAKAYSLDEERHRRLMWEENKKKIEAHN 78
Query: 64 LIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFD 123
K G+N+F+DL+ +EF+ + + E +P D
Sbjct: 79 ADYERGKTSFYMGLNQFSDLTPEEFR------------TNCCGSSMCRGEMAPDLPEYED 126
Query: 124 WRTRGAVTPVKNQ 136
+TP + Q
Sbjct: 127 LGKNSYLTPGRAQ 139
>sp|P32957|CC4_CARCN CYSTEINE PROTEINASE IV (CC-IV)
Length = 43
Score = 84.6 bits (206), Expect = 3e-16
Identities = 26/42 (61%), Positives = 30/42 (70%)
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN 160
P + DWR +GAVTPVKNQG CGSCW+FST VEG + I
Sbjct: 2 PESIDWRKKGAVTPVKNQGSCGSCWAFSTIVTVEGINKIRTG 43
>sp|P32956|CC3_CARCN CYSTEINE PROTEINASE III (CC-III)
Length = 43
Score = 84.2 bits (205), Expect = 4e-16
Identities = 26/42 (61%), Positives = 30/42 (70%)
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN 160
P + DWR +GAVTPVKNQG CGSCW+FST VEG + I
Sbjct: 2 PESIDWRKKGAVTPVKNQGSCGSCWAFSTIATVEGINKIVHG 43
>sp|P32955|CC2_CARCN CYSTEINE PROTEINASE II (CC-II)
Length = 43
Score = 81.5 bits (198), Expect = 2e-15
Identities = 24/42 (57%), Positives = 29/42 (68%)
Query: 119 PTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN 160
P + DWR +GAVTPVK+Q CGSCW+FST VEG + I
Sbjct: 2 PGSVDWRQKGAVTPVKDQNPCGSCWAFSTVATVEGINKIVTG 43
>sp||CATL_CHICK_2 [Segment 2 of 2] CATHEPSIN L
Length = 42
Score = 77.2 bits (187), Expect = 5e-14
Identities = 20/42 (47%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
Query: 303 NMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 343
YWIVKNSWG WG++GYIY+ + KN CG++ S ++
Sbjct: 1 GKKYWIVKNSWGEKWGDKGYIYMAKDRKNHCGIATAASYPLV 42
>sp|P32954|CC1_CARCN CYSTEINE PROTEINASE I (CC-I)
Length = 43
Score = 76.0 bits (184), Expect = 1e-13
Identities = 24/40 (60%), Positives = 29/40 (72%)
Query: 118 IPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFI 157
I + DWR +GAVTPV+NQG CGSCW+FS+ VEG I
Sbjct: 1 IVASIDWRQKGAVTPVRNQGSCGSCWTFSSVAAVEGIIKI 40
>sp|P05689|CATX_BOVIN CATHEPSIN
Length = 73
Score = 59.7 bits (142), Expect = 9e-09
Identities = 15/41 (36%), Positives = 24/41 (57%), Gaps = 5/41 (12%)
Query: 285 DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
+H + + G+ + M YWIV+NSWG WGE G++ +
Sbjct: 10 NHIVSVAGWGVSD-----GMEYWIVRNSWGEPWGEHGWMRI 45
>sp|P94869|PEPG_LACDL AMINOPEPTIDASE G
Length = 437
Score = 46.0 bits (107), Expect = 1e-04
Identities = 13/49 (26%), Positives = 21/49 (42%), Gaps = 4/49 (8%)
Query: 280 NPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG 328
+ H + +VG R+ W V+NSWG GE+G+ +
Sbjct: 355 GAGEVSHAMTLVGVDEDKGDIRQ----WKVENSWGDKSGEKGFFVMSHN 399
>sp|P94870|PEPE_LACHE AMINOPEPTIDASE E
Length = 438
Score = 42.9 bits (99), Expect = 0.001
Identities = 14/48 (29%), Positives = 21/48 (43%), Gaps = 4/48 (8%)
Query: 278 PCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
+ H + +VG N R+ W V+NSWG G +GY +
Sbjct: 354 KTGVGEVSHAMTLVGVDEDNGEVRQ----WKVENSWGDKSGAKGYYVM 397
>sp|P94868|PEPW_LACDL AMINOPEPTIDASE W
Length = 437
Score = 42.1 bits (97), Expect = 0.002
Identities = 14/43 (32%), Positives = 20/43 (45%), Gaps = 4/43 (9%)
Query: 286 HGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG 328
H + +VG R+ W V+NSWG GE+GY +
Sbjct: 361 HDMALVGVDVDGGQVRQ----WKVENSWGDKSGEKGYFTMSAD 399
>sp|Q10744|PEPC_LACHE AMINOPEPTIDASE C
Length = 449
Score = 41.4 bits (95), Expect = 0.003
Identities = 13/46 (28%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 280 NPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
+ +DH ++I G + K W ++NSWG G +GY +
Sbjct: 358 GESMMDHAMVITGVDIVDGKPTK----WKIENSWGEKPGFKGYFVM 399
>sp|Q04723|PEPC_LACLC AMINOPEPTIDASE C
Length = 436
Score = 39.8 bits (91), Expect = 0.009
Identities = 15/68 (22%), Positives = 29/68 (42%), Gaps = 9/68 (13%)
Query: 262 ADAVEWQ------FYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGA 315
D+ +++ F + + + H +++ G + N W V+NSWG
Sbjct: 326 MDSYDFKSSLDIEFTQSKAGRLDYGESLMTHAMVLAG---VDLDADGNSTKWKVENSWGK 382
Query: 316 DWGEQGYI 323
D G++GY
Sbjct: 383 DAGQKGYF 390
Score = 31.6 bits (70), Expect = 2.5
Identities = 15/77 (19%), Positives = 28/77 (35%), Gaps = 10/77 (12%)
Query: 77 VNKFADLSS---DEFKN--YYLNNKEAIFTDDLPVADYLDDEFINSIPT-AFDWRTRGAV 130
+ +D + + F + A+ + L + + ++P + D
Sbjct: 1 MTVTSDFTQKLYENFAENTKLRAVENAVTKNGLLSSLEVRGSHAANLPEFSLDLTKD--- 57
Query: 131 TPVKNQGQCGSCWSFST 147
PV NQ Q G CW F+
Sbjct: 58 -PVTNQKQSGRCWMFAA 73
>sp|Q48543|PEPC_LACDL AMINOPEPTIDASE C
Length = 449
Score = 38.2 bits (87), Expect = 0.025
Identities = 12/46 (26%), Positives = 23/46 (49%), Gaps = 4/46 (8%)
Query: 280 NPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYL 325
+ ++H ++I A + + K W ++NSWG G +GY +
Sbjct: 358 GESMMNHAMVIT---AVDLVDDKPTK-WKIENSWGDKSGFKGYFVM 399
>sp|P21381|THPA_THADA THAUMATOPAIN
Length = 35
Score = 38.2 bits (87), Expect = 0.025
Identities = 14/27 (51%), Positives = 19/27 (69%), Gaps = 2/27 (7%)
Query: 117 SIPTAFDWRTRGAVTPVKNQGQ-CGSC 142
++P + DW +GAV VKNQ + CGSC
Sbjct: 1 NLPNSVDWWKKGAVAAVKNQ-RXCGSC 26
>sp|Q56115|PEPC_STRTR AMINOPEPTIDASE C
Length = 445
Score = 35.9 bits (81), Expect = 0.13
Identities = 11/46 (23%), Positives = 21/46 (44%), Gaps = 5/46 (10%)
Query: 279 CNPNSLDHGILIVGYSAKNTIFRKNMPY-WIVKNSWGADWGEQGYI 323
+ + + H +++ G P W ++NSWG G++GY
Sbjct: 356 YSESLMTHAMVLTGVDLD----ADGKPIKWKIENSWGDKVGQKGYF 397
>sp|P09983|HLY1_ECOLI HEMOLYSIN, CHROMOSOMAL
Length = 1023
Score = 35.5 bits (80), Expect = 0.17
Identities = 21/119 (17%), Positives = 35/119 (28%), Gaps = 20/119 (16%)
Query: 31 EFQDKFNKKYSHEEYLERFEIF-KSNLGKIEELNLIAI-------NHKADTKF-----GV 77
E++ K K Y Y R F + N + + N + GV
Sbjct: 430 EWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGV 489
Query: 78 NKFAD--LSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVK 134
+ D LS + +YY K D + + + D + T +K
Sbjct: 490 TRNGDKTLSGKSYIDYYEEGKR-----LEKKPDEFQKQVFDPLKGNIDLSDSKSSTLLK 543
>sp|P33403|CYSP_TRIFO CYSTEINE PROTEINASE
Length = 23
Score = 34.7 bits (78), Expect = 0.28
Identities = 8/19 (42%), Positives = 12/19 (63%)
Query: 120 TAFDWRTRGAVTPVKNQGQ 138
+ DWR +G V +K+Q Q
Sbjct: 2 DSLDWREKGVVNSIKDQAQ 20
>sp|P08715|HLYA_ECOLI HEMOLYSIN, PLASMID
Length = 1024
Score = 34.7 bits (78), Expect = 0.28
Identities = 9/38 (23%), Positives = 14/38 (36%), Gaps = 1/38 (2%)
Query: 31 EFQDKFNKKYSHEEYLERFEIF-KSNLGKIEELNLIAI 67
E++ K K Y Y R F + N + + N
Sbjct: 431 EWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYS 468
>sp|P87362|BLMH_CHICK BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) (AMINOPEPTIDASE H)
Length = 455
Score = 34.3 bits (77), Expect = 0.37
Identities = 10/19 (52%), Positives = 14/19 (73%)
Query: 307 WIVKNSWGADWGEQGYIYL 325
W V+NSWG D G +GY+ +
Sbjct: 392 WRVENSWGEDRGNKGYLIM 410
>sp|P54704|PSPB_DICDI PRESPORE PROTEIN B PRECURSOR
Length = 379
Score = 34.3 bits (77), Expect = 0.37
Identities = 24/109 (22%), Positives = 41/109 (37%), Gaps = 15/109 (13%)
Query: 210 TESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQF 269
T YP T G +N + K + ++PK E + Y+ GP D W++
Sbjct: 78 TGKIYP-TVNMGDCHRYNVDLVFKKDKSGNVMPKKELRESAYVP-HGP----IDPATWKY 131
Query: 270 YI--GGVFDI-PCNPNSL------DHGILIVGYSAKNTIFRKNMPYWIV 309
Y G + C+P ++ L +GY A + W++
Sbjct: 132 YTFVQGKWTGFGCDPQNVVFSGAEGGMPLQLGYGANGKNGDNGISVWLI 180
>sp|Q13867|BLMH_HUMAN BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH)
Length = 455
Score = 34.0 bits (76), Expect = 0.49
Identities = 10/19 (52%), Positives = 14/19 (73%)
Query: 307 WIVKNSWGADWGEQGYIYL 325
W V+NSWG D G +GY+ +
Sbjct: 392 WRVENSWGEDHGHKGYLCM 410
>sp|P70645|BLMH_RAT BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH)
Length = 454
Score = 34.0 bits (76), Expect = 0.49
Identities = 10/19 (52%), Positives = 14/19 (73%)
Query: 307 WIVKNSWGADWGEQGYIYL 325
W V+NSWG D G +GY+ +
Sbjct: 392 WRVENSWGEDHGHKGYLCM 410
>sp|P80532|CAT3_FASHE PUTATIVE CATHEPSIN L3 (NEWLY EXCYSTED JUVENILE PROTEIN 8)
Length = 19
Score = 34.0 bits (76), Expect = 0.49
Identities = 9/18 (50%), Positives = 12/18 (66%)
Query: 118 IPTAFDWRTRGAVTPVKN 135
+P + DWR G VT VK+
Sbjct: 2 VPASIDWREYGYVTEVKD 19
>sp|P16462|LKTA_ACTAC LEUKOTOXIN
Length = 1050
Score = 34.0 bits (76), Expect = 0.49
Identities = 11/68 (16%), Positives = 25/68 (36%), Gaps = 2/68 (2%)
Query: 12 FTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKA 71
+ S I + + +++K+ K YS Y R F ++ N + +K
Sbjct: 410 ASKQAVSEHIANQLADKIKAWENKYGKNYSENGYDARHSAFLE--DSLKLFNELREKYKT 467
Query: 72 DTKFGVNK 79
+ + +
Sbjct: 468 ENILSITQ 475
>sp|P13438|TSP_MOUSE TROPHOBLAST-SPECIFIC PROTEIN PRECURSOR
Length = 124
Score = 32.4 bits (72), Expect = 1.4
Identities = 19/129 (14%), Positives = 41/129 (31%), Gaps = 12/129 (9%)
Query: 8 VLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAI 67
L + + V+S I PE Q + K +E L + ++ + + +
Sbjct: 6 FLVILCLGVASAVIVPEAQLDAELQEQK------DKEVLIK-AVWSKFMKTNKLHSSEND 58
Query: 68 NHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTR 127
+ ++ L+ +E +F ++ + + P D+
Sbjct: 59 QETEGSNIEMSASGQLTDEELMKIMTTVLHPMFEEEENKP-----QPVVDDPEFEDYTES 113
Query: 128 GAVTPVKNQ 136
G V NQ
Sbjct: 114 GDGFFVPNQ 122
>sp|Q00951|HLYA_ACTSU HEMOLYSIN (CYTOLYSIN II) (CLY-IIA) (HLY-IIA) (CYTC) (APPA)
Length = 956
Score = 32.4 bits (72), Expect = 1.4
Identities = 10/36 (27%), Positives = 16/36 (43%), Gaps = 1/36 (2%)
Query: 31 EFQDKFNKKYSHEEYLER-FEIFKSNLGKIEELNLI 65
E++ K NK Y + Y R + N+ + LN
Sbjct: 427 EWEKKHNKNYFEQGYDSRHLADLQDNMKFLINLNKE 462
>sp|P15377|RT2A_ACTPL RTX-II TOXIN DETERMINANT A (APX-IIA) (HEMOLYSIN IIA) (HLY-IIA)
(CYTOLYSIN IIA) (CLY-IIA)
Length = 956
Score = 32.4 bits (72), Expect = 1.4
Identities = 10/36 (27%), Positives = 16/36 (43%), Gaps = 1/36 (2%)
Query: 31 EFQDKFNKKYSHEEYLER-FEIFKSNLGKIEELNLI 65
E++ K NK Y + Y R + N+ + LN
Sbjct: 427 EWEKKHNKNYFEQGYDSRHLADLQDNMKFLINLNKE 462
>sp|P52181|TGLC_PAGMA PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE (TISSUE
TRANSGLUTAMINASE) (TGASE C) (TGC)
Length = 695
Score = 32.0 bits (71), Expect = 1.9
Identities = 12/48 (25%), Positives = 17/48 (35%), Gaps = 5/48 (10%)
Query: 102 DDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTG 149
++ + S+P W G V PVK G CW F+
Sbjct: 237 EEPYTDGVAPYRWTGSVPILQQWSKAG-VRPVKY----GQCWVFAAVA 279
>sp|P35681|TCTP_ORYSA TRANSLATIONALLY CONTROLLED TUMOR PROTEIN HOMOLOG (TCTP)
Length = 168
Score = 32.0 bits (71), Expect = 1.9
Identities = 12/34 (35%), Positives = 19/34 (55%)
Query: 22 PPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSN 55
PP ++ QF+ F ++ K S + E+ E FK N
Sbjct: 80 PPFDKKQFVTFMKRYIKNLSAKLDAEKQEEFKKN 113
>sp|Q01532|BLH1_YEAST CYSTEINE PROTEINASE 1 (Y3) (BLEOMYCIN HYDROLASE) (BLM HYDROLASE)
Length = 454
Score = 31.6 bits (70), Expect = 2.5
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 9/40 (22%)
Query: 131 TPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNL 170
TPV NQ G CW F+ T + +L LSE NL
Sbjct: 62 TPVTNQKSSGRCWLFAATNQL---------RLNVLSELNL 92
>sp|P16312|MMAL_DERMI MAJOR MITE FECAL ALLERGEN DER M 1 (DER M I)
Length = 30
Score = 31.2 bits (69), Expect = 3.2
Identities = 8/24 (33%), Positives = 14/24 (58%)
Query: 114 FINSIPTAFDWRTRGAVTPVKNQG 137
++P+ D R+ VTP++ QG
Sbjct: 7 NSGNVPSELDLRSLRTVTPIRMQG 30
>sp|O03992|TCTP_FRAAN TRANSLATIONALLY CONTROLLED TUMOR PROTEIN HOMOLOG (TCTP)
Length = 170
Score = 30.8 bits (68), Expect = 4.2
Identities = 16/62 (25%), Positives = 30/62 (47%), Gaps = 13/62 (20%)
Query: 22 PPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFA 81
PP ++ QF+ + ++ K + + E+ E FK N+ + TKF ++K +
Sbjct: 82 PPFDKKQFVTWVKRYIKLLTPKLEGEQQETFKKNI-------------EGATKFLLSKLS 128
Query: 82 DL 83
DL
Sbjct: 129 DL 130
>sp|Q04489|YMJ6_YEAST HYPOTHETICAL 59.5 KD PROTEIN IN VPS9-RAD10 INTERGENIC REGION
Length = 525
Score = 30.8 bits (68), Expect = 4.2
Identities = 26/122 (21%), Positives = 43/122 (34%), Gaps = 20/122 (16%)
Query: 174 DHECMEYEGEEACDEGCNGGLQPNAYNYIIKN-----GGIQ----TESSYPYTAET--GT 222
D +++ GE E G +++N G I E Y YT +
Sbjct: 87 DRYFLQFNGELYNKEISQGDNDSLYIASMLQNLKEGMGVIDVIKSLEGEYAYTIYDVNSS 146
Query: 223 QCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPN 282
+ F IG + ++++ P NE +A ++ A +Q IGGV
Sbjct: 147 KLYFGRDPIGRRSLSYSVTPDNELYVA---------SVTGSAGSFQDCIGGVIYEYDTRT 197
Query: 283 SL 284
L
Sbjct: 198 KL 199
>sp|Q03164|HRX_HUMAN ZINC FINGER PROTEIN HRX (ALL-1) (TRITHORAX-LIKE PROTEIN)
Length = 3969
Score = 30.8 bits (68), Expect = 4.2
Identities = 17/81 (20%), Positives = 38/81 (45%), Gaps = 7/81 (8%)
Query: 126 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDC-DHECMEYEGEE 184
+V+ VK QGQ S + ++E + + S++NL+D + E ++ + +
Sbjct: 2782 NCHSVSRVKTQGQ-DSLEA--QLSSLESSRRVHTSTP---SDKNLLDTYNTELLKSDSDN 2835
Query: 185 ACDEGCNGGLQPNAYNYIIKN 205
+ C L + ++++KN
Sbjct: 2836 NNSDDCGNILPSDIMDFVLKN 2856
>sp||CATB_COTJA_1 [Segment 1 of 2] CATHEPSIN B (CATHEPSIN B1)
Length = 25
Score = 30.4 bits (67), Expect = 5.6
Identities = 6/25 (24%), Positives = 12/25 (48%), Gaps = 4/25 (16%)
Query: 118 IPTAFD----WRTRGAVTPVKNQGQ 138
+P FD W ++ +++QG
Sbjct: 1 LPDTFDSRKQWPNCPTISEIRDQGS 25
>sp|Q62703|RCN2_RAT RETICULOCALBIN 2 PRECURSOR (CALCIUM-BINDING PROTEIN ERC-55)
(TAIPOXIN-ASSOCIATED CALCIUM-BINDING PROTEIN-49)
(TCBP-49)
Length = 318
Score = 30.4 bits (67), Expect = 5.6
Identities = 17/109 (15%), Positives = 40/109 (36%), Gaps = 4/109 (3%)
Query: 26 QSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIA-INHKADTKFGVNKFADLS 84
+++ ++ K Y+ +E ++F + N + + F N D +
Sbjct: 84 ENELSQWIQMSFKHYAMQEAKQQFVEYDKNSDGTVTWDEYNVQMYDRVIDFDENTALDDT 143
Query: 85 SDE-FKNYYLNNKEAIFTDDLPVADYLDDEFINSI--PTAFDWRTRGAV 130
+E F+ +L +K+ + L+ E + P D+ T +
Sbjct: 144 EEESFRQLHLKDKKRFEKANQDSGPGLNLEEFIAFEHPEEVDYMTEFVI 192
>sp|P48651|PSS1_HUMAN PHOSPHATIDYLSERINE SYNTHASE I (SERINE-EXCHANGE ENZYME I) (KIAA0024)
Length = 473
Score = 30.4 bits (67), Expect = 5.6
Identities = 6/20 (30%), Positives = 8/20 (40%)
Query: 142 CWSFSTTGNVEGQHFISQNK 161
CW F G +E I +
Sbjct: 354 CWVFGVIGFLEAIVCIKFGQ 373
>sp|P33404|CYSP_TRIVA CYSTEINE PROTEINASE
Length = 22
Score = 30.4 bits (67), Expect = 5.6
Identities = 10/17 (58%), Positives = 13/17 (75%), Gaps = 1/17 (5%)
Query: 123 DWRTRGAVTPV-KNQGQ 138
DWR +GAV + K+QGQ
Sbjct: 6 DWRKKGAVNVIXKDQGQ 22
>sp|Q00576|PSS1_CRILO PHOSPHATIDYLSERINE SYNTHASE I (SERINE-EXCHANGE ENZYME I)
Length = 471
Score = 30.4 bits (67), Expect = 5.6
Identities = 6/20 (30%), Positives = 8/20 (40%)
Query: 142 CWSFSTTGNVEGQHFISQNK 161
CW F G +E I +
Sbjct: 354 CWVFGVIGFLEAIVCIKFGQ 373
>sp|Q9ZRX0|TCTP_PSEMZ TRANSLATIONALLY CONTROLLED TUMOR PROTEIN HOMOLOG (TCTP)
Length = 167
Score = 30.1 bits (66), Expect = 7.3
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 13/62 (20%)
Query: 22 PPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFA 81
PP ++ QFL F ++ K + + ER FK N+ + K V+K +
Sbjct: 79 PPFDKKQFLGFIKRYIKNLATKLSEERQAEFKKNV-------------EGAAKMLVSKLS 125
Query: 82 DL 83
DL
Sbjct: 126 DL 127
>sp|Q94480|V136_DICDI VEG136 PROTEIN
Length = 357
Score = 30.1 bits (66), Expect = 7.3
Identities = 21/95 (22%), Positives = 34/95 (35%), Gaps = 3/95 (3%)
Query: 70 KADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGA 129
+G++ F LS DE Y ++ + Y I S ++W
Sbjct: 79 NKKYDYGLDLFL-LSIDEGITGYRDDSLETVKRNQEQ--YPIPSQILSYKELYNWTMDDI 135
Query: 130 VTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVS 164
V + +G C SC F G + NK+V+
Sbjct: 136 VKEIGLKGNCTSCGVFRRQALDRGAVMLKANKIVT 170
>sp|P55131|RT32_ACTPL RTX-III TOXIN DETERMINANT A FROM SEROTYPE 8 (APX-IIIA) (CYTOLYSIN
IIIA) (CLY-IIIA)
Length = 1052
Score = 30.1 bits (66), Expect = 7.3
Identities = 9/53 (16%), Positives = 21/53 (38%), Gaps = 1/53 (1%)
Query: 20 GIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIF-KSNLGKIEELNLIAINHKA 71
+ + ++ E++ K+ K Y Y R + F + + + N +A
Sbjct: 427 HVASKIGNKIDEWEKKYGKNYFENGYDARHKAFLEDSFSLLSSFNKQYETERA 479
>sp|P55130|RT31_ACTPL RTX-III TOXIN DETERMINANT A FROM SEROTYPE 2 (APX-IIIA) (CYTOLYSIN
IIIA) (CLY-IIIA)
Length = 1049
Score = 30.1 bits (66), Expect = 7.3
Identities = 9/53 (16%), Positives = 21/53 (38%), Gaps = 1/53 (1%)
Query: 20 GIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIF-KSNLGKIEELNLIAINHKA 71
+ + ++ E++ K+ K Y Y R + F + + + N +A
Sbjct: 427 HVASKIGNKIDEWEKKYGKNYFENGYDARHKAFLEDSFSLLSSFNKQYETERA 479
>sp|P40101|YE16_YEAST HYPOTHETICAL 35.9 KD PROTEIN IN ISC10 3'REGION
Length = 306
Score = 30.1 bits (66), Expect = 7.3
Identities = 13/48 (27%), Positives = 16/48 (33%), Gaps = 1/48 (2%)
Query: 199 YNY-IIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNE 245
Y Y I+KNG ES Y E F K+ + E
Sbjct: 103 YQYEILKNGDFPEESDYEVKGECDGFTLFKVLFCTVKVKKTSYYRNKE 150
>sp|P13388|XMRK_XIPMA MELANOMA RECEPTOR PROTEIN-TYROSINE KINASE PRECURSOR
Length = 1166
Score = 30.1 bits (66), Expect = 7.3
Identities = 16/54 (29%), Positives = 23/54 (41%), Gaps = 11/54 (20%)
Query: 140 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGG 193
GSCW+ H KL+ +EQ C+ C + + C+E C GG
Sbjct: 202 GSCWAPGPG------HCQKFTKLL-CAEQ----CNRRCRGPKPIDCCNEHCAGG 244
>sp|Q9ZL75|MOAA_HELPJ MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A
Length = 321
Score = 29.7 bits (65), Expect = 9.5
Identities = 23/162 (14%), Positives = 51/162 (31%), Gaps = 9/162 (5%)
Query: 41 SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIF 100
+ +E LE E K+ +I + + H G+ + L K + ++
Sbjct: 165 NDDEILELLEYAKNRSIQIRYIEFMENTHAKSLVKGLKEKEILDLIAQKYKIMGMEKPKQ 224
Query: 101 TDDLPVADYLDDEFINSIPTAFDW-RTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQ 159
+F P + D+ ++ + + C + E
Sbjct: 225 GSSKIYTLENGYQFGIIAPHSDDFCQSCNRIRLASDGKICPCLYYQDAIDAKEAIINKDT 284
Query: 160 NKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNY 201
+ L +Q++++ + M + NGG A+ Y
Sbjct: 285 KMMKRLLKQSIINKPEKNMWNDK--------NGGTPTRAFYY 318
>sp|P55129|RT12_ACTPL RTX-I TOXIN DETERMINANT A FROM SEROTYPES 5/10 (APX-IA) (HEMOLYSIN
IA) (HLY-IA) (CYTOLYSIN IA) (CLY-IA)
Length = 1023
Score = 29.7 bits (65), Expect = 9.5
Identities = 8/42 (19%), Positives = 15/42 (35%), Gaps = 1/42 (2%)
Query: 27 SQFLEFQDKFNKKYSHEEYLERFEIF-KSNLGKIEELNLIAI 67
++ E++ K K Y Y R F + + + N
Sbjct: 423 NKIDEWEKKHGKNYFENGYDARHSAFLEDTFELLSQYNKEYS 464
>sp|P55128|RT11_ACTPL RTX-I TOXIN DETERMINANT A FROM SEROTYPES 1/9 (APX-IA) (HEMOLYSIN
IA) (HLY-IA) (CYTOLYSIN IA) (CLY-IA)
Length = 1023
Score = 29.7 bits (65), Expect = 9.5
Identities = 8/42 (19%), Positives = 15/42 (35%), Gaps = 1/42 (2%)
Query: 27 SQFLEFQDKFNKKYSHEEYLERFEIF-KSNLGKIEELNLIAI 67
++ E++ K K Y Y R F + + + N
Sbjct: 423 NKIDEWEKKHGKNYFENGYDARHSAFLEDTFELLSQYNKEYS 464
>sp|P35669|GSHB_SCHPO GLUTATHIONE SYNTHETASE LARGE CHAIN (GLUTATHIONE SYNTHASE LARGE
CHAIN) (GSH SYNTHETASE LARGE CHAIN) (GSH-S)
(PHYTOCHELATIN SYNTHETASE)
Length = 498
Score = 29.7 bits (65), Expect = 9.5
Identities = 16/67 (23%), Positives = 26/67 (37%), Gaps = 6/67 (8%)
Query: 33 QDKFNKKYSHEEYLERFE------IFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
Q +NK Y+ F I K + + NL + +A N+F LS
Sbjct: 66 QKAYNKLYAKIANDYEFLRLHLQSITKYDEFMNKLWNLYQKHREAVAHLKENQFQPLSLG 125
Query: 87 EFKNYYL 93
F++ Y+
Sbjct: 126 VFRSDYM 132
>sp|P11140|ABRA_ABRPR ABRIN-A PRECURSOR (RRNA N-GLYCOSIDASE)
Length = 528
Score = 29.7 bits (65), Expect = 9.5
Identities = 12/59 (20%), Positives = 22/59 (36%), Gaps = 2/59 (3%)
Query: 152 EGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQT 210
E Q + + + S QN +C +G GC+ G + + +G I +
Sbjct: 436 EQQWALYTDGSIR-SVQNTNNCLTSKDHKQGSTILLMGCSNGWASQRWVF-KNDGSIYS 492
>sp|Q00690|LEM2_MOUSE E-SELECTIN PRECURSOR (ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1)
(ELAM-1) (LEUKOCYTE-ENDOTHELIAL CELL ADHESION MOLECULE
2) (LECAM2) (CD62E)
Length = 612
Score = 29.7 bits (65), Expect = 9.5
Identities = 7/30 (23%), Positives = 13/30 (43%)
Query: 171 VDCDHECMEYEGEEACDEGCNGGLQPNAYN 200
++C H + +C GC G P++
Sbjct: 191 LNCSHPFGPFSYNSSCSFGCKRGYLPSSME 220
>sp|P06620|ICEN_PSESY ICE NUCLEATION PROTEIN
Length = 1200
Score = 29.7 bits (65), Expect = 9.5
Identities = 9/33 (27%), Positives = 13/33 (39%), Gaps = 3/33 (9%)
Query: 277 IPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIV 309
N + +H LI GY + T W+V
Sbjct: 194 YGSNETAGNHSDLIAGYGSTGTA---GSDSWLV 223
Database: /home/peter/blast/data/swissprot.pr
Posted date: Oct 10, 2000 10:43 AM
Number of letters in database: 31,984,247
Number of sequences in database: 88,780
Lambda K H
0.318 0.140 0.482
Lambda K H
0.270 0.0491 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48087047
Number of Sequences: 88780
Number of extensions: 2165712
Number of successful extensions: 7103
Number of sequences better than 10.0: 284
Number of HSP's better than 10.0 without gapping: 253
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 5661
Number of HSP's gapped (non-prelim): 339
length of query: 343
length of database: 31,984,247
effective HSP length: 49
effective length of query: 294
effective length of database: 27,634,027
effective search space: 8124403938
effective search space used: 8124403938
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 65 (29.7 bits)