format-version: 1.4
date: 01:04:2011 17:51
default-namespace: APO
auto-generated-by: ONTO-PERL
remark: The Cell-Cycle Ontology
[Term]
id: APO:R0000168
name: ECK
def: "The EcoGene Database of Escherichia coli Sequence and Function" []
is_a: APO:R0000000 ! reference
comment: http://www.ecogene.org/
created_by: erick_antezana
creation_date: 2010-04-13T01:32:36Z
[Term]
id: APO:R0000007
name: BIOSIS
def: "BIOSIS previews" []
is_a: APO:R0000000 ! reference
comment: http://www.biosis.org/
[Term]
id: APO:P0000175
name: preblastoderm mitotic cell cycle
def: "The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis." [ISBN:0879694238]
is_a: APO:P0000193 ! mitotic cell cycle, embryonic
xref: GO:0035185
[Term]
id: APO:R0000111
name: PSORT
def: "PSORT protein subcellular localization databases and prediction tools for bacteria" []
is_a: APO:R0000000 ! reference
comment: http://www.psort.org/
[Term]
id: APO:R0000077
name: MGI
def: "Mouse Genome Informatics" []
is_a: APO:R0000000 ! reference
comment: http://www.informatics.jax.org/
[Term]
id: APO:P0000039
name: cytokinesis after mitosis
def: "The processes resulting in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." [GOC:ai]
relationship: part_of APO:P0000016 ! M phase of mitotic cell cycle
xref: GO:0000281
[Term]
id: APO:B0000073
name: KRP5
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000057 ! cell cycle arrest
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "AT3G24810" EXACT []
synonym: "KIP-RELATED PROTEIN 5" EXACT []
synonym: "K7P8.10" EXACT []
xref: TAIR:gene:2087247
[Term]
id: APO:P0000288
name: positive regulation of progression through meiotic cell cycle
def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai]
is_a: APO:P0000199 ! positive regulation of progression through cell cycle
is_a: APO:P0000287 ! regulation of progression through meiotic cell cycle
synonym: "positive regulation of meiotic cell cycle progression" EXACT []
xref: GO:0051446
[Term]
id: APO:P0000005
name: cell cycle checkpoint
def: "A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage." [GOC:mah, ISBN:0815316194]
is_a: APO:P0000004 ! regulation of progression through cell cycle
xref: GO:0000075
xref: Reactome:69620
[Term]
id: APO:B0000046
name: CDKD1;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F25P22.11" EXACT []
synonym: "CYCLIN-DEPENDENT KINASE D1;1" EXACT []
synonym: "F25P22_11" EXACT []
synonym: "AT1G73690" EXACT []
synonym: "AT;CDKD;1" EXACT []
synonym: "CAK3AT" EXACT []
xref: TAIR:gene:2027818
[Term]
id: APO:R0000138
name: TIGR_CMR
def: "The Institute for Genomic Research, Comprehensive Microbial Resource" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/
[Term]
id: APO:P0000060
name: male meiosis I spindle assembly (sensu Metazoa)
def: "The formation of the spindle during meiosis I of a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
is_a: APO:P0000059 ! male meiotic spindle assembly (sensu Metazoa)
relationship: part_of APO:P0000118 ! male meiosis I
xref: GO:0007054
[Term]
id: APO:P0000222
name: regulation of centriole replication
def: "Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole." [GOC:ai]
is_a: APO:P0000228 ! regulation of centrosome cycle
relationship: part_of APO:P0000097 ! centriole replication
xref: GO:0046599
[Term]
id: APO:P0000115
name: meiotic anaphase II
def: "Progression through anaphase of meiosis II; analogous to mitotic anaphase." [GOC:mah]
is_a: APO:P0000266 ! anaphase
relationship: part_of APO:P0000112 ! meiosis II
xref: GO:0007138
[Term]
id: APO:P0000307
name: cell cycle arrest of committed forebrain neuronal progenitor cell
def: "The process by which progression through the cell cycle is halted in a cell that has been committed to become a neuron that will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447]
is_a: APO:P0000057 ! cell cycle arrest
xref: GO:0021883
[Term]
id: APO:P0000300
name: meiotic sister chromatid centromere separation
def: "The process by which the centromeres of sister chromatids are physically detached from each other during meiosis." [GOC:ai, PMID:14730319, PMID:16325576]
relationship: part_of APO:P0000301 ! meiotic sister chromatid separation
relationship: part_of APO:P0000192 ! meiotic sister chromatid segregation
xref: GO:0051756
[Term]
id: APO:P0000250
name: establishment of meiotic spindle orientation
def: "The processes that set the alignment of meiotic spindle relative to other cellular structures." [GOC:ai]
is_a: APO:P0000249 ! establishment of meiotic spindle localization
synonym: "establishment of spindle orientation during meiosis" EXACT []
synonym: "meiotic spindle orientation" EXACT []
synonym: "orienting of meiotic spindle" EXACT []
xref: GO:0051296
[Term]
id: APO:P0000169
name: G1/S-specific positive regulation of cyclin-dependent protein kinase activity
def: "Any process that activates or increases the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah]
is_a: APO:P0000195 ! positive regulation of cyclin-dependent protein kinase activity
is_a: APO:P0000167 ! G1/S-specific regulation of cyclin-dependent protein kinase activity
xref: GO:0031659
[Term]
id: APO:P0000191
name: homologous chromosome segregation
def: "The process by which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, ISBN:0815316194]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
relationship: part_of APO:P0000104 ! meiosis I
synonym: "meiosis I, chromosome segregation" EXACT []
xref: GO:0045143
xref: GO:0007061
[Term]
id: APO:P0000134
name: meiotic chromosome movement towards spindle pole
def: "The directed movement of chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis." [GOC:ai]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
synonym: "chromosome migration to spindle pole during meiosis" EXACT []
synonym: "chromosome movement towards spindle pole during meiosis" EXACT []
synonym: "meiotic chromosome movement to spindle pole" EXACT []
synonym: "meiotic chromosome movement" BROAD []
xref: GO:0016344
[Term]
id: APO:R0000080
name: MultiFun
def: "MultiFun, a cellfunction assignment schema" []
is_a: APO:R0000000 ! reference
comment: http://genprotec.mbl.edu/files/Multifun.html
[Term]
id: APO:R0000139
name: TIGR_EGAD
def: "The Institute for Genomic Research, EGAD database" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/
[Term]
id: APO:P0000179
name: polar body extrusion after meiotic divisions
def: "The generation of two small cells, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes." [GOC:ems, ISBN:0198506732]
relationship: part_of APO:P0000120 ! female meiosis
xref: GO:0040038
[Term]
id: APO:P0000217
name: positive regulation of transcription from RNA polymerase I promoter, mitotic
def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators]
is_a: APO:P0000207 ! positive regulation of transcription, mitotic
is_a: APO:P0000216 ! regulation of transcription from RNA polymerase I promoter, mitotic
synonym: "mitotic activation of transcription from Pol I promoter" EXACT []
synonym: "positive regulation of transcription from Pol I promoter, mitotic" EXACT []
xref: GO:0046018
[Term]
id: APO:B0000144
name: AT1G20590.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F5M15.8" EXACT []
synonym: "F5M15_8" EXACT []
synonym: "AT1G20590" EXACT []
xref: TAIR:gene:3690291
[Term]
id: APO:P0000214
name: negative regulation of progression through syncytial blastoderm mitotic cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the syncytial blastoderm mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000210 ! negative regulation of progression through embryonic mitotic cell cycle
is_a: APO:P0000126 ! regulation of progression through syncytial blastoderm mitotic cell cycle
synonym: "negative regulation of syncytial blastoderm cell cycle progression" EXACT []
xref: GO:0046003
[Term]
id: APO:R0000062
name: ISSN
def: "International Standard Serial Number" []
is_a: APO:R0000000 ! reference
comment: http://www.issn.org/
[Term]
id: APO:P0000068
name: female meiosis sister chromatid cohesion
def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female." [GOC:ai]
is_a: APO:P0000240 ! meiotic sister chromatid cohesion
relationship: part_of APO:P0000120 ! female meiosis
xref: GO:0007066
[Term]
id: APO:R0000035
name: GeneDB_Gmorsitans
def: "GeneDB_Gmorsitans" []
is_a: APO:R0000000 ! reference
comment: http://www.genedb.org/genedb/glossina/
[Term]
id: APO:B0000063
name: CKS2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "AT2G27970" EXACT []
synonym: "CDK-subunit 2" EXACT []
synonym: "T1E2_11" EXACT []
synonym: "T1E2.11" EXACT []
xref: TAIR:gene:2057824
[Term]
id: APO:P0000160
name: intra-S DNA damage checkpoint
def: "The slowing of DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progession." [GOC:vw]
is_a: APO:P0000007 ! DNA damage checkpoint
xref: GO:0031573
[Term]
id: APO:P0000085
name: vesicle fusion with nuclear membrane
def: "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus." [GOC:jic]
relationship: part_of APO:P0000084 ! mitotic nuclear envelope reassembly
synonym: "vesicle fusion" BROAD []
xref: GO:0007086
[Term]
id: APO:P0000099
name: male meiosis centrosome cycle
def: "Centrosome duplication and separation in the context of male meiosis." [GOC:mah]
is_a: APO:P0000096 ! centrosome cycle
xref: GO:0007101
[Term]
id: APO:R0000147
name: TRANSFAC
def: "TRANSFAC database of eukaryotic transcription factors" []
is_a: APO:R0000000 ! reference
comment: http://www.gene-regulation.com/pub/databases.html#transfac
[Term]
id: APO:R0000131
name: taxon
def: "NCBI Taxman" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/Taxonomy/taxonomyhome.html/
[Term]
id: APO:R0000050
name: H-invDB
def: "H-invitational Database" []
is_a: APO:R0000000 ! reference
comment: http://www.h-invitational.jp/
[Term]
id: APO:B0000022
name: ATRAD51C
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000103 ! meiosis
relationship: participates_in APO:P0000108 ! meiotic recombination
relationship: participates_in APO:P0000120 ! female meiosis
relationship: participates_in APO:P0000117 ! male meiosis
synonym: "AT2G45280" EXACT []
synonym: "RAD51C" EXACT []
xref: TAIR:gene:1006154140
[Term]
id: APO:B0000092
name: MLH3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000108 ! meiotic recombination
synonym: "MUTL PROTEIN HOMOLOG 3" EXACT []
synonym: "F8D20_30" EXACT []
synonym: "ATMLH3" EXACT []
synonym: "AT4G35520" EXACT []
synonym: "F8D20.30" EXACT []
xref: TAIR:gene:2127922
[Term]
id: APO:B0000101
name: AT5G61650.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT5G61650" EXACT []
synonym: "K11J9_17" EXACT []
synonym: "K11J9.17" EXACT []
xref: TAIR:gene:2151655
[Term]
id: APO:R0000085
name: NCBI_GP
def: "NCBI GenPept" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/
[Term]
id: APO:P0000084
name: mitotic nuclear envelope reassembly
def: "The reformation of the nuclear envelope during mitotic cell division." [GOC:ai]
relationship: part_of APO:P0000037 ! mitotic cell cycle
xref: GO:0007084
[Term]
id: APO:R0000091
name: PDB
def: "Protein Data Bank" []
is_a: APO:R0000000 ! reference
comment: http://www.rcsb.org/pdb/
[Term]
id: APO:P0000234
name: regulation of transcription, meiotic
def: "Any process that modulates the frequency, rate or extent of transcription during meiosis." [GOC:go_curators]
relationship: part_of APO:P0000103 ! meiosis
synonym: "meiotic regulation of transcription" EXACT []
xref: GO:0051037
[Term]
id: APO:U0000004
name: gene
def: "A locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions and/or other functional sequence regions." [SO:0000704]
disjoint_from: APO:U0000005
is_a: APO:U0000003 ! biopolymer
xref: SO:0000704
[Term]
id: APO:P0000277
name: meiotic nuclear envelope reassembly
def: "The reformation of the nuclear envelope during meiosis." [GOC:ai]
relationship: part_of APO:P0000265 ! meiotic cell cycle
xref: GO:0051333
[Term]
id: APO:P0000303
name: sister chromosome movement towards spindle pole during meiosis II
def: "The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II." [GOC:ai]
is_a: APO:P0000134 ! meiotic chromosome movement towards spindle pole
relationship: part_of APO:P0000192 ! meiotic sister chromatid segregation
synonym: "meiosis II, sister chromosome movement towards spindle pole" EXACT []
xref: GO:0051759
[Term]
id: APO:B0000122
name: PCNA1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "PROLIFERATING CELLULAR NUCLEAR ANTIGEN" EXACT []
synonym: "AT1G07370" EXACT []
xref: TAIR:gene:3353025
[Term]
id: APO:B0000113
name: CYCD7;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "Cyclin D7;1" EXACT []
synonym: "AT5G02110" EXACT []
synonym: "T7H20.160" EXACT []
synonym: "T7H20_160" EXACT []
xref: TAIR:gene:2185177
[Term]
id: APO:R0000141
name: TIGR_Pfa1
def: "The Institute for Genomic Research, Plasmodium falciparum database" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/tdb/e2k1/pfa1/pfa1.shtml
[Term]
id: APO:P0000159
name: G2/M transition DNA damage checkpoint
def: "A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase in response to DNA damage." [GOC:mah]
is_a: APO:P0000007 ! DNA damage checkpoint
is_a: APO:P0000163 ! G2/M transition checkpoint
xref: GO:0031572
[Term]
id: APO:R0000058
name: IntAct
def: "IntAct protein interaction database" []
is_a: APO:R0000000 ! reference
comment: http://www.ebi.ac.uk/intact/
[Term]
id: APO:P0000006
name: DNA replication checkpoint
def: "A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome." [GOC:rn, PMID:11728327, PMID:12537518]
is_a: APO:P0000157 ! DNA integrity checkpoint
xref: GO:0000076
[Term]
id: APO:P0000157
name: DNA integrity checkpoint
def: "Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure." [GOC:mah, GOC:vw]
is_a: APO:P0000005 ! cell cycle checkpoint
xref: GO:0031570
[Term]
id: APO:P0000044
name: meiotic DNA recombinase assembly
def: "During meiosis, the assembly of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA." [GOC:elh, PMID:11459983]
relationship: part_of APO:P0000054 ! meiotic gene conversion
relationship: part_of APO:P0000108 ! meiotic recombination
xref: GO:0000707
[Term]
id: APO:P0000295
name: cell cycle switching, meiotic to mitotic cell cycle
def: "The process by which a cell switches cell cycle mode from meiotic to mitotic division." [GOC:ai]
is_a: APO:P0000294 ! regulation of cell cycle
synonym: "conversion to mitotic cell cycle" EXACT []
synonym: "entry into mitotic cell cycle" EXACT []
synonym: "initiation of mitotic cell cycle" EXACT []
synonym: "cell cycle switching, meiotis to mitosis" NARROW []
synonym: "conversion to mitosis" NARROW []
synonym: "entry into mitosis" NARROW []
synonym: "initiation of mitosis" NARROW []
synonym: "mitotic entry" NARROW []
xref: GO:0051727
[Term]
id: APO:P0000076
name: activation of transcription on exit from mitosis, from RNA polymerase II promoter
is_a: APO:P0000074 ! activation of transcription on exit from mitosis
synonym: "activation of transcription on exit from mitosis, from Pol II promoter" EXACT []
xref: GO:0007074
[Term]
id: APO:B0000108
name: ATMAP65-1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000266 ! anaphase
synonym: "MCO15_18" EXACT []
synonym: "MCO15.18" EXACT []
synonym: "AT5G55230" EXACT []
xref: TAIR:gene:2161649
[Term]
id: APO:P0000283
name: regulation of ubiquitin ligase activity during mitotic cell cycle
def: "Any process that modulates the frequency, rate or extent of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai]
relationship: part_of APO:P0000037 ! mitotic cell cycle
synonym: "regulation of ubiquitin-protein ligase activity during mitotic cell cycle" EXACT []
synonym: "mitotic anaphase-promoting complex regulator" NARROW []
synonym: "mitotic APC regulator" NARROW []
synonym: "mitotic SCF complex regulator" NARROW []
synonym: "mitotic ubiquitin ligase regulator" RELATED []
synonym: "mitotic ubiquitin-protein ligase regulator" RELATED []
xref: GO:0051439
[Term]
id: APO:P0000259
name: attachment of spindle microtubules to kinetochore during mitosis
def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex during mitosis. During mitosis, the kinetochores of sister chromosomes are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs." [GOC:ai, GOC:clt]
relationship: part_of APO:P0000002 ! mitotic sister chromatid segregation
xref: GO:0051315
[Term]
id: APO:P0000182
name: late meiotic recombination nodule assembly
def: "The assembly of small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over." [GOC:jl, PMID:9334324]
is_a: APO:P0000122 ! meiotic recombination nodule assembly
xref: GO:0042140
[Term]
id: APO:P0000022
name: mitotic telophase
def: "Progression through telophase, the last of the stages of mitosis; in the canonical cell cycle, telophase begins when the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [ISBN:0721662544]
is_a: APO:P0000270 ! telophase
relationship: part_of APO:P0000069 ! mitosis
xref: GO:0000093
[Term]
id: APO:P0000033
name: zygotene
def: "Progression through the second stage of prophase I in meiosis, in which each chromosome pairs with its homolog; the two become aligned and crossing over may occur." [ISBN:0198547684]
relationship: part_of APO:P0000105 ! meiotic prophase I
xref: GO:0000238
[Term]
id: APO:R0000070
name: MaizeGDB_Locus
def: "MaizeGDB" []
is_a: APO:R0000000 ! reference
comment: http://www.maizegdb.org
[Term]
id: APO:B0000014
name: CYCD2;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000010 ! G1 phase of mitotic cell cycle
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G22490" EXACT []
synonym: "F14M13.11" EXACT []
synonym: "CYCLIN D2;1" EXACT []
synonym: "F14M13_11" EXACT []
xref: TAIR:gene:1005867820
xref: TAIR:gene:2041192
[Term]
id: APO:P0000176
name: syncytial blastoderm mitotic cell cycle
def: "Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively." [ISBN:0879694238]
is_a: APO:P0000193 ! mitotic cell cycle, embryonic
xref: GO:0035186
[Term]
id: APO:P0000237
name: meiotic nuclear envelope disassembly
def: "The controlled breakdown of the nuclear envelope during meiotic cell division." [GOC:bf]
relationship: part_of APO:P0000265 ! meiotic cell cycle
synonym: "meiotic nuclear envelope breakdown" EXACT []
synonym: "meiotic nuclear envelope degradation" EXACT []
xref: GO:0051078
[Term]
id: APO:B0000129
name: SYN3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000069 ! mitosis
synonym: "AT3G59550" EXACT []
xref: TAIR:gene:3355040
[Term]
id: APO:R0000046
name: GR
def: "Gramene: A Comparative Mapping Resource for Grains" []
is_a: APO:R0000000 ! reference
comment: http://www.gramene.org/
[Term]
id: APO:P0000224
name: positive regulation of centriole replication
def: "Any process that activates or increases the frequency, rate or extent of centriole replication." [GOC:ai]
is_a: APO:P0000222 ! regulation of centriole replication
is_a: APO:P0000230 ! positive regulation of centrosome cycle
xref: GO:0046601
[Term]
id: APO:R0000016
name: CL
def: "Cell Type Ontology" []
is_a: APO:R0000000 ! reference
comment: https://lists.sourceforge.net/lists/listinfo/obo-cell-type
[Term]
id: APO:B0000037
name: MOR1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000130 ! cell plate formation (sensu Magnoliophyta)
synonym: "AT2G35630" EXACT []
synonym: "MICROTUBULE ORGANIZATION 1" EXACT []
synonym: "GEM1" EXACT []
xref: TAIR:gene:1945220
[Term]
id: APO:R0000108
name: PROW
def: "Protein Reviews on the Web" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/prow/
[Term]
id: APO:R0000067
name: LIGAND
def: "KEGG LIGAND Database" []
is_a: APO:R0000000 ! reference
comment: http://www.genome.ad.jp/kegg/docs/upd_ligand.html#COMPOUND
[Term]
id: APO:R0000156
name: WB_GENE
def: "WormBase, database of nematode biology" []
is_a: APO:R0000000 ! reference
comment: http://www.wormbase.org/
[Term]
id: APO:P0000010
name: G1 phase of mitotic cell cycle
def: "Progression through G1 phase, one of two 'gap' phases in the mitotic cell cycle; G1 is the interval between the completion of mitosis and the beginning of DNA synthesis." [ISBN:0815316194]
is_a: APO:P0000262 ! G1 phase
relationship: part_of APO:P0000273 ! interphase of mitotic cell cycle
xref: GO:0000080
xref: Reactome:69236
[Term]
id: APO:B0000152
name: ASY2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000107 ! synaptonemal complex formation
synonym: "AT4G32200" EXACT []
xref: TAIR:gene:3714891
[Term]
id: APO:P0000174
name: attachment of telomeres to spindle pole body
def: "The formation of physical connections between telomeres and the spindle pole body, facilitating bouquet formation." [PMID:16615890]
relationship: part_of APO:P0000190 ! telomere clustering
xref: GO:0032121
[Term]
id: APO:R0000110
name: PSI-MI
def: "Proteomic Standard Initiative for Molecular Interaction" []
is_a: APO:R0000000 ! reference
comment: http://psidev.sourceforge.net/mi/xml/doc/user/index.html
[Term]
id: APO:P0000109
name: meiotic metaphase I
def: "Progression through metaphase of meiosis I; analogous to mitotic metaphase." [GOC:mah]
is_a: APO:P0000267 ! metaphase
relationship: part_of APO:P0000104 ! meiosis I
xref: GO:0007132
[Term]
id: APO:P0000040
name: re-entry into mitotic cell cycle
def: "The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state." [GOC:krc]
is_a: APO:P0000004 ! regulation of progression through cell cycle
xref: GO:0000320
[Term]
id: APO:P0000025
name: G2-specific transcription in mitotic cell cycle
def: "Any process that regulates transcription such that the target genes are transcribed during the G2 phase of the mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000014 ! G2 phase of mitotic cell cycle
xref: GO:0000116
[Term]
id: APO:P0000297
name: germline cell cycle switching, mitotic to meiotic cell cycle
def: "The process by which a germline cell switches cell cycle mode from mitotic to meiotic division." [GOC:ai]
is_a: APO:P0000296 ! cell cycle switching, mitotic to meiotic cell cycle
synonym: "germline conversion to meiotic cell cycle" EXACT []
synonym: "germline entry into meiotic cell cycle" EXACT []
synonym: "germline initiation of meiotic cell cycle" EXACT []
synonym: "germline cell cycle switching, mitotis to meiosis" NARROW []
synonym: "germline conversion to meiosis" NARROW []
synonym: "germline entry into meiosis" NARROW []
synonym: "germline initiation of meiosis" NARROW []
synonym: "germline meiotic entry" NARROW []
xref: GO:0051729
[Term]
id: APO:P0000087
name: regulation of mitosis
def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators]
is_a: APO:P0000004 ! regulation of progression through cell cycle
relationship: part_of APO:P0000069 ! mitosis
xref: GO:0007088
xref: Reactome:73674
[Term]
id: APO:P0000184
name: meiotic metaphase II plate congression
def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II." [GOC:cab1, PMID:10809666]
is_a: APO:P0000257 ! meiotic metaphase plate congression
relationship: part_of APO:P0000192 ! meiotic sister chromatid segregation
xref: GO:0043061
[Term]
id: APO:P0000108
name: meiotic recombination
def: "The formation and repair of double strand breaks through a double Holliday junction intermediate that results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity." [PMID:2087779]
relationship: part_of APO:P0000104 ! meiosis I
synonym: "gene conversion with reciprocal crossover" EXACT []
synonym: "female meiotic recombination" NARROW []
xref: GO:0007131
xref: GO:0000021
xref: GO:0007145
[Term]
id: APO:P0000078
name: mitotic chromosome condensation
def: "Compaction of chromatin structure prior to mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194]
relationship: part_of APO:P0000002 ! mitotic sister chromatid segregation
xref: GO:0007076
[Term]
id: APO:P0000158
name: G1 DNA damage checkpoint
def: "A cell cycle checkpoint that arrests cell cycle progression G1 phase in response to DNA damage." [GOC:mah]
is_a: APO:P0000007 ! DNA damage checkpoint
xref: GO:0031571
[Term]
id: APO:R0000024
name: EC
def: "The Enzyme Commission" []
is_a: APO:R0000000 ! reference
comment: http://www.chem.qmw.ac.uk/iubmb/enzyme/
[Term]
id: APO:P0000114
name: meiotic metaphase II
def: "Progression through metaphase of meiosis II; analogous to mitotic metaphase." [GOC:mah]
is_a: APO:P0000267 ! metaphase
relationship: part_of APO:P0000112 ! meiosis II
xref: GO:0007137
[Term]
id: APO:B0000016
name: CDKB1;2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G38620" EXACT []
xref: TAIR:gene:1005867830
[Term]
id: APO:B0000047
name: CYCA3;2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G47210" EXACT []
synonym: "Cyclin A3;2" EXACT []
synonym: "F8G22.8" EXACT []
synonym: "F8G22_8" EXACT []
xref: TAIR:gene:2030647
[Term]
id: APO:B0000082
name: AT3G48150.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "T24C20.30" EXACT []
synonym: "AT3G48150" EXACT []
xref: TAIR:gene:2100438
[Term]
id: APO:R0000153
name: UniProtKB
def: "The Universal Protein Knowledgebase, a central repository of protein sequence and function created by joining the information contained in Swiss-Prot, TrEMBL, and PIR" []
is_a: APO:R0000000 ! reference
comment: http://www.uniprot.org
[Term]
id: APO:B0000013
name: CYCD4;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000010 ! G1 phase of mitotic cell cycle
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT5G65420" EXACT []
synonym: "MNA5_15" EXACT []
synonym: "CYCLIN D4;1" EXACT []
synonym: "MNA5.15" EXACT []
xref: TAIR:gene:1005867818
xref: TAIR:gene:2168251
[Term]
id: APO:R0000076
name: MGD
def: "Mouse Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.informatics.jax.org/
[Term]
id: APO:P0000260
name: attachment of spindle microtubules to kinetochore during meiotic chromosome segregation
def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiotic chromosome segregation." [GOC:ai]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
synonym: "attachment of spindle microtubules to kinetochore during meiosis" RELATED []
xref: GO:0051316
[Term]
id: APO:B0000103
name: AT5G48630.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "K15N18_10" EXACT []
synonym: "AT5G48630" EXACT []
synonym: "K15N18.10" EXACT []
xref: TAIR:gene:2152540
[Term]
id: APO:P0000167
name: G1/S-specific regulation of cyclin-dependent protein kinase activity
def: "Any process that modulates the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah]
is_a: APO:P0000009 ! regulation of cyclin-dependent protein kinase activity
relationship: part_of APO:P0000011 ! G1/S transition of mitotic cell cycle
xref: GO:0031657
[Term]
id: APO:B0000072
name: AT3G22880.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000108 ! meiotic recombination
synonym: "F5N5.6" EXACT []
synonym: "AT3G22880" EXACT []
xref: TAIR:gene:2084557
[Term]
id: APO:B0000100
name: AT5G08290
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000069 ! mitosis
synonym: "F8L15_20" EXACT []
synonym: "F8L15.20" EXACT []
xref: TAIR:gene:2150767
[Term]
id: APO:P0000218
name: regulation of transcription from RNA polymerase II promoter, mitotic
def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators]
relationship: part_of APO:P0000206 ! regulation of transcription, mitotic
synonym: "mitotic regulation of transcription from Pol II promoter" EXACT []
synonym: "regulation of transcription from Pol II promoter, mitotic" EXACT []
xref: GO:0046021
[Term]
id: APO:P0000133
name: second mitotic wave (sensu Endopterygota)
def: "A discrete cell cycle that occurs during the third instar eye imaginal disc after progression of the morphogenetic furrow. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392)." [PMID:11257224]
is_a: APO:P0000056 ! cell cycle
xref: GO:0016330
[Term]
id: APO:U0000000
name: cell-cycle entity
def: "A process or continuant." [APO:ea]
synonym: "cell cycle entity" EXACT [APO:ea]
[Term]
id: APO:R0000037
name: GeneDB_Pfalciparum
def: "GeneDB_Pfalciparum" []
is_a: APO:R0000000 ! reference
comment: http://www.genedb.org/genedb/malaria/
[Term]
id: APO:P0000267
name: metaphase
def: "Progression through metaphase, the second stage of chromosome segregation in the cell cycle. Canonically, chromosomes become aligned on the equatorial plate of the cell." [http:www.onelook.com]
relationship: part_of APO:P0000038 ! M phase
xref: GO:0051323
[Term]
id: APO:P0000204
name: negative regulation of mitotic metaphase/anaphase transition
def: "Any process that stops, prevents or reduces the frequency, rate or extent of the mitotic metaphase to anaphase transition." [GOC:go_curators]
is_a: APO:P0000202 ! negative regulation of mitosis
is_a: APO:P0000139 ! regulation of mitotic metaphase/anaphase transition
xref: GO:0045841
[Term]
id: APO:R0000055
name: HUGO
def: "Human Genome Organisation" []
is_a: APO:R0000000 ! reference
comment: http://www.hugo-international.org/
[Term]
id: APO:P0000004
name: regulation of progression through cell cycle
def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:go_curators]
is_a: APO:P0000294 ! regulation of cell cycle
synonym: "control of cell cycle progression" EXACT []
synonym: "modulation of cell cycle progression" EXACT []
synonym: "regulation of cell cycle progression" EXACT []
synonym: "cell cycle regulator" RELATED []
synonym: "RHEB small monomeric GTPase activity" RELATED []
synonym: "tumor suppressor" RELATED []
xref: GO:0000074
xref: Reactome:156678
xref: Reactome:156699
xref: Reactome:156711
xref: Reactome:162657
xref: Reactome:165167
xref: Reactome:167104
xref: Reactome:167109
xref: Reactome:169311
xref: Reactome:171117
xref: Reactome:171122
xref: Reactome:174455
xref: Reactome:177752
xref: Reactome:177757
[Term]
id: APO:P0000112
name: meiosis II
def: "Progression through the second phase of meiosis, in which cells divide and separate the two chromatids in each chromosome." [ISBN:0198547684]
relationship: part_of APO:P0000103 ! meiosis
xref: GO:0007135
[Term]
id: APO:P0000118
name: male meiosis I
def: "The first meiotic division in the male germline." [GOC:mah]
relationship: part_of APO:P0000117 ! male meiosis
xref: GO:0007141
[Term]
id: APO:R0000092
name: Pfam
def: "Pfam: Protein families database of alignments and HMMs" []
is_a: APO:R0000000 ! reference
comment: http://www.sanger.ac.uk/Software/Pfam/
[Term]
id: APO:B0000097
name: CYCH;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT5G27620" EXACT []
synonym: "F15A18.80" EXACT []
synonym: "F15A18_80" EXACT []
xref: TAIR:gene:2143670
[Term]
id: APO:P0000067
name: male meiosis sister chromatid cohesion
def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male." [GOC:ai]
is_a: APO:P0000240 ! meiotic sister chromatid cohesion
relationship: part_of APO:P0000117 ! male meiosis
xref: GO:0007065
[Term]
id: APO:P0000070
name: negative regulation of transcription, mitotic
def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription during mitosis." [GOC:go_curators]
is_a: APO:P0000206 ! regulation of transcription, mitotic
synonym: "mitotic repression of transcription" EXACT []
xref: GO:0007068
[Term]
id: APO:P0000306
name: maintenance of contractile ring localization
def: "The processes by which a contractile ring is maintained in a location and prevented from moving elsewhere." [GOC:mah]
relationship: part_of APO:P0000153 ! cytokinesis, contractile ring maintenance
synonym: "cytokinetic ring anchoring" RELATED []
xref: GO:0032189
[Term]
id: APO:P0000221
name: positive regulation of transcription from RNA polymerase III promoter, mitotic
def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators]
is_a: APO:P0000207 ! positive regulation of transcription, mitotic
is_a: APO:P0000220 ! regulation of transcription from RNA polymerase III promoter, mitotic
synonym: "mitotic activation of transcription from Pol III promoter" EXACT []
synonym: "positive regulation of transcription from Pol III promoter, mitotic" EXACT []
xref: GO:0046024
[Term]
id: APO:B0000064
name: AT2G32590.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000069 ! mitosis
relationship: participates_in APO:P0000037 ! mitotic cell cycle
synonym: "T26B15.15" EXACT []
synonym: "AT2G32590" EXACT []
synonym: "T26B15_15" EXACT []
xref: TAIR:gene:2060272
[Term]
id: APO:B0000143
name: AT1G76310.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F15M4.19" EXACT []
synonym: "AT1G76310" EXACT []
xref: TAIR:gene:3687660
[Term]
id: APO:R0000114
name: PubChem_Substance
def: "NCBI PubChem database of chemical substances" []
is_a: APO:R0000000 ! reference
comment: http://pubchem.ncbi.nlm.nih.gov/
[Term]
id: APO:R0000165
name: DOI
def: "Digital Object Identifier" []
is_a: APO:R0000000 ! reference
comment: http://www.doi.org/
[Term]
id: APO:P0000265
name: meiotic cell cycle
def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell." [GOC:ai]
is_a: APO:P0000056 ! cell cycle
xref: GO:0051321
[Term]
id: APO:B0000059
name: KRP1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "KIP-RELATED PROTEIN 1" EXACT []
synonym: "F26B6.8" EXACT []
synonym: "F26B6_8" EXACT []
synonym: "AT2G23430" EXACT []
xref: TAIR:gene:2046777
[Term]
id: APO:P0000187
name: G0 to G1 transition
def: "The transition from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression." [ISBN:0716731363]
is_a: APO:P0000040 ! re-entry into mitotic cell cycle
xref: GO:0045023
[Term]
id: APO:B0000109
name: CYCA3;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "MMG4.10" EXACT []
synonym: "Cyclin A3;1" EXACT []
synonym: "AT5G43080" EXACT []
synonym: "MMG4_10" EXACT []
xref: TAIR:gene:2167760
[Term]
id: APO:R0000095
name: PharmGKB_PGKB
def: "The Pharmacogenetics and Pharmacogenomics Knowledge Base" []
is_a: APO:R0000000 ! reference
comment: http://www.pharmgkb.org
[Term]
id: APO:P0000034
name: pachytene
def: "Progression through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." [ISBN:0198547684]
relationship: part_of APO:P0000105 ! meiotic prophase I
xref: GO:0000239
[Term]
id: APO:P0000156
name: G2/M transition size control checkpoint
def: "A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase until cells have reached a critical size." [GOC:mah]
is_a: APO:P0000154 ! cell size control checkpoint
is_a: APO:P0000163 ! G2/M transition checkpoint
xref: GO:0031569
[Term]
id: APO:R0000140
name: TIGR_GenProp
def: "The Institute for Genomic Research, Genome Properties" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/
[Term]
id: APO:B0000146
name: AT3G16320.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "AT3G16320" EXACT []
synonym: "MYA6.15" EXACT []
xref: TAIR:gene:3702575
[Term]
id: APO:R0000123
name: SGD_REF
def: "Saccharomyces Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.yeastgenome.org/
[Term]
id: APO:B0000021
name: XRCC2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000108 ! meiotic recombination
synonym: "AT5G64520" EXACT []
xref: TAIR:gene:1006154139
[Term]
id: APO:P0000202
name: negative regulation of mitosis
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitosis." [GOC:go_curators]
is_a: APO:P0000087 ! regulation of mitosis
is_a: APO:P0000198 ! negative regulation of progression through cell cycle
xref: GO:0045839
[Term]
id: APO:B0000104
name: AT5G48640.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "K15N18_11" EXACT []
synonym: "K15N18.11" EXACT []
synonym: "AT5G48640" EXACT []
xref: TAIR:gene:2152555
[Term]
id: APO:B0000118
name: AT1G75950.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000069 ! mitosis
relationship: participates_in APO:P0000117 ! male meiosis
synonym: "T4O12.17" EXACT []
synonym: "AT1G75950" EXACT []
synonym: "T4O12_17" EXACT []
xref: TAIR:gene:2204434
[Term]
id: APO:P0000126
name: regulation of progression through syncytial blastoderm mitotic cell cycle
def: "Any process that modulates the frequency, rate or extent of the progression through the syncytial blastoderm mitotic cell cycle." [GOC:go_curators]
relationship: part_of APO:P0000129 ! regulation of progression through embryonic mitotic cell cycle
relationship: part_of APO:P0000176 ! syncytial blastoderm mitotic cell cycle
synonym: "control of syncytial blastoderm cell cycle progression" EXACT []
synonym: "modulation of syncytial blastoderm cell cycle progression" EXACT []
synonym: "regulation of syncytial blastoderm cell cycle" EXACT []
synonym: "regulation of syncytial blastoderm cell cycle progression" EXACT []
synonym: "syncytial blastoderm cell cycle control" EXACT []
synonym: "syncytial blastoderm cell cycle modulation" EXACT []
synonym: "syncytial blastoderm cell cycle regulation" EXACT []
synonym: "syncytial blastoderm cell cycle regulator" RELATED []
xref: GO:0007348
[Term]
id: APO:P0000168
name: G1/S-specific negative regulation of cyclin-dependent protein kinase activity
def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah]
is_a: APO:P0000167 ! G1/S-specific regulation of cyclin-dependent protein kinase activity
is_a: APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
xref: GO:0031658
[Term]
id: APO:U0000005
name: protein
def: "One or more polypeptides which may, or may not, be covalently bonded, and which assume a native secondary and tertiary structure." [SO:0000358]
disjoint_from: APO:U0000004
is_a: APO:U0000003 ! biopolymer
xref: SO:0000358
[Term]
id: APO:B0000051
name: CYCA2;4
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "Cyclin A2;4" EXACT []
synonym: "AT1G80370" EXACT []
synonym: "F5I6_12" EXACT []
synonym: "F5I6.12" EXACT []
xref: TAIR:gene:2034249
[Term]
id: APO:R0000137
name: TIGR_Ath1
def: "The Institute for Genomic Research, Arabidopsis thaliana database" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/tdb/e2k1/ath1/ath1.shtml
[Term]
id: APO:P0000258
name: attachment of spindle microtubules to mitotic chromosome
def: "The process by which spindle microtubules become physically associated with a chromosome during mitosis." [GOC:ai]
relationship: part_of APO:P0000002 ! mitotic sister chromatid segregation
xref: GO:0051314
[Term]
id: APO:B0000079
name: AT3G25980.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000093 ! mitotic spindle checkpoint
synonym: "AT3G25980" EXACT []
synonym: "MPE11.16" EXACT []
xref: TAIR:gene:2092124
[Term]
id: APO:B0000155
name: UGT1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000130 ! cell plate formation (sensu Magnoliophyta)
synonym: "UDP-GLUCOSYLTRANSFERASE" EXACT []
synonym: "AT1G05560" EXACT []
synonym: "UGT75B1" EXACT []
xref: TAIR:gene:3716068
[Term]
id: APO:P0000086
name: mitotic nuclear pore complex reassembly
def: "The reformation of nuclear pore complexes during mitotic cell division." [GOC:ai]
relationship: part_of APO:P0000084 ! mitotic nuclear envelope reassembly
xref: GO:0007087
[Term]
id: APO:R0000047
name: GR_MUT
def: "Gramene: A Comparative Mapping Resource for Grains" []
is_a: APO:R0000000 ! reference
comment: http://www.gramene.org/
[Term]
id: APO:R0000004
name: AGRICOLA_IND
def: "AGRICultural OnLine Access" []
is_a: APO:R0000000 ! reference
comment: http://agricola.cos.com/
[Term]
id: APO:P0000233
name: chiasma formation
def: "The formation of a connection between chromatids, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids." [http:www.onelook.com]
relationship: part_of APO:P0000106 ! synapsis
xref: GO:0051026
[Term]
id: APO:B0000017
name: TSK
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000015 ! G2/M transition of mitotic cell cycle
synonym: "BRU1" EXACT []
synonym: "TONSOKU" EXACT []
synonym: "MGO3" EXACT []
synonym: "MGOUN3" EXACT []
synonym: "AT3G18730" EXACT []
synonym: "BRUSHY1" EXACT []
xref: TAIR:gene:1005898774
[Term]
id: APO:B0000038
name: AT1G14750.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F10B6_15" EXACT []
synonym: "F10B6.15" EXACT []
synonym: "AT1G14750" EXACT []
xref: TAIR:gene:2006826
[Term]
id: APO:R0000160
name: http
is_a: APO:R0000000 ! reference
[Term]
id: APO:R0000087
name: NCBI_NP
def: "NCBI RefSeq" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/
[Term]
id: APO:P0000101
name: cytokinesis after meiosis II
def: "The processes resulting in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells." [GOC:ai]
relationship: part_of APO:P0000271 ! M phase of meiotic cell cycle
xref: GO:0007111
[Term]
id: APO:B0000050
name: CDKD1;2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000009 ! regulation of cyclin-dependent protein kinase activity
synonym: "CAK4AT" EXACT []
synonym: "CYCLIN-DEPENDENT KINASE D1;2" EXACT []
synonym: "F4N21_12" EXACT []
synonym: "CDKD;2" EXACT []
synonym: "F4N21.12" EXACT []
synonym: "AT;CDKD;2" EXACT []
synonym: "AT1G66750" EXACT []
xref: TAIR:gene:2033348
[Term]
id: APO:B0000054
name: AT1G78770.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "F9K20_19" EXACT []
synonym: "F9K20.19" EXACT []
synonym: "AT1G78770" EXACT []
xref: TAIR:gene:2037522
[Term]
id: APO:B0000135
name: CDKF;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000009 ! regulation of cyclin-dependent protein kinase activity
synonym: "F19B15_10" EXACT []
synonym: "F19B15.10" EXACT []
synonym: "AT4G28980" EXACT []
synonym: "CAK1AT" EXACT []
synonym: "CYCLIN-DEPENDENT KINASE F;1" EXACT []
xref: TAIR:gene:3438808
[Term]
id: APO:R0000086
name: NCBI_NM
def: "NCBI RefSeq" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/
[Term]
id: APO:B0000123
name: GCR1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000037 ! mitotic cell cycle
synonym: "G-PROTEIN-COUPLED RECEPTOR 1" EXACT []
synonym: "AT1G48270" EXACT []
xref: TAIR:gene:3353428
[Term]
id: APO:R0000036
name: GeneDB_Lmajor
def: "GeneDB_Lmajor" []
is_a: APO:R0000000 ! reference
comment: http://www.genedb.org/genedb/leish/
[Term]
id: APO:P0000199
name: positive regulation of progression through cell cycle
def: "Any process that activates or increases the frequency, rate or extent of progression through the cell cycle." [GOC:go_curators]
is_a: APO:P0000004 ! regulation of progression through cell cycle
synonym: "positive regulation of cell cycle progression" EXACT []
xref: GO:0045787
[Term]
id: APO:P0000240
name: meiotic sister chromatid cohesion
def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis." [GOC:ai]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
relationship: part_of APO:P0000104 ! meiosis I
xref: GO:0051177
[Term]
id: APO:P0000151
name: positive regulation of exit from mitosis
def: "Any processactivates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:mah]
is_a: APO:P0000095 ! regulation of exit from mitosis
xref: GO:0031536
[Term]
id: APO:P0000294
name: regulation of cell cycle
def: "Any process that modulates the rate, extent or mode of the cell cycle." [GOC:ai]
relationship: part_of APO:P0000056 ! cell cycle
synonym: "cell cycle control" EXACT []
synonym: "cell cycle modulation" EXACT []
synonym: "cell cycle regulation" EXACT []
xref: GO:0051726
[Term]
id: APO:P0000096
name: centrosome cycle
def: "The process of centrosome duplication and separation. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle." [ISBN:0815316194]
relationship: part_of APO:P0000056 ! cell cycle
xref: GO:0007098
[Term]
id: APO:P0000247
name: mitotic spindle midzone assembly
def: "The formation of the mitotic spindle midzone, the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GOC:ai]
relationship: part_of APO:P0000243 ! mitotic spindle assembly
synonym: "mitotic spindle midzone biogenesis" EXACT []
synonym: "mitotic spindle midzone formation" EXACT []
synonym: "spindle midzone assembly during mitosis" EXACT []
synonym: "spindle midzone biogenesis during mitosis" EXACT []
synonym: "spindle midzone formation during mitosis" EXACT []
xref: GO:0051256
[Term]
id: APO:P0000091
name: anaphase-promoting complex activation during mitotic cell cycle
def: "Any process that activates, maintains or increases the rate of the ubiquitin ligase activity of the anaphase-promoting complex during the mitotic cell cycle." [GOC:mah, PMID:10871297]
is_a: APO:P0000282 ! positive regulation of ubiquitin ligase activity during mitotic cell cycle
relationship: part_of APO:P0000139 ! regulation of mitotic metaphase/anaphase transition
synonym: "activation of ubiquitin ligase activity of anaphase promoting complex during mitotic cell cycle" EXACT []
synonym: "activation of ubiquitin ligase activity of anaphase-promoting complex during mitotic cell cycle" EXACT []
synonym: "activation of ubiquitin ligase activity of APC during mitotic cell cycle" EXACT []
synonym: "anaphase promoting complex activation during mitotic cell cycle" EXACT []
synonym: "APC activation during mitotic cell cycle" EXACT []
synonym: "mitotic anaphase promoting complex activation" EXACT []
synonym: "mitotic anaphase-promoting complex activation" EXACT []
synonym: "mitotic APC activation" EXACT []
synonym: "mitotic anaphase promoting complex activator" NARROW []
synonym: "mitotic anaphase-promoting complex activator" NARROW []
synonym: "mitotic APC activator" NARROW []
xref: GO:0007092
xref: Reactome:162659
xref: Reactome:163010
xref: Reactome:165237
xref: Reactome:166428
xref: Reactome:169381
xref: Reactome:170447
xref: Reactome:173214
xref: Reactome:173955
xref: Reactome:176216
xref: Reactome:177163
[Term]
id: APO:B0000154
name: MEI1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000108 ! meiotic recombination
relationship: participates_in APO:P0000120 ! female meiosis
relationship: participates_in APO:P0000117 ! male meiosis
synonym: "AT1G77320" EXACT []
xref: TAIR:gene:3715385
[Term]
id: APO:P0000018
name: mitotic metaphase
def: "Progression through metaphase, the stage of mitosis at which chromosomes are firmly attached to the mitotic spindle at its equator but have not yet segregated to opposite poles." [ISBN:0815316194]
is_a: APO:P0000267 ! metaphase
relationship: part_of APO:P0000069 ! mitosis
xref: GO:0000089
xref: Reactome:68879
[Term]
id: APO:P0000238
name: meiosis I nuclear envelope disassembly
def: "The controlled breakdown of the nuclear envelope during the first division of meiosis." [GOC:bf]
is_a: APO:P0000237 ! meiotic nuclear envelope disassembly
relationship: part_of APO:P0000104 ! meiosis I
synonym: "meiosis I nuclear envelope breakdown" EXACT []
synonym: "meiosis I nuclear envelope degradation" EXACT []
xref: GO:0051079
[Term]
id: APO:P0000077
name: activation of transcription on exit from mitosis, from RNA polymerase III promoter
is_a: APO:P0000074 ! activation of transcription on exit from mitosis
synonym: "activation of transcription on exit from mitosis, from Pol III promoter" EXACT []
xref: GO:0007075
[Term]
id: APO:P0000190
name: telomere clustering
def: "The dynamic reorganization of telomeres in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in homologous chromosome pairing and therefore progression through meiosis." [GOC:vw, PMID:10690419]
relationship: part_of APO:P0000103 ! meiosis
synonym: "bouquet formation" NARROW []
xref: GO:0045141
[Term]
id: APO:B0000025
name: AT1G47230.2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G47230" EXACT []
xref: TAIR:gene:1006229846
[Term]
id: APO:B0000035
name: HBT
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000124 ! regulation of progression through mitotic cell cycle
synonym: "AT2G20000" EXACT []
synonym: "HOBBIT" EXACT []
xref: TAIR:gene:1945154
[Term]
id: APO:R0000060
name: IPI
def: "International Protein Index" []
is_a: APO:R0000000 ! reference
comment: http://www.ebi.ac.uk/IPI/IPIhelp.html
[Term]
id: APO:R0000019
name: COG_Function
def: "NCBI COG function" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/COG/
[Term]
id: APO:R0000130
name: TAIR
def: "The Arabidopsis Information Resource" []
is_a: APO:R0000000 ! reference
comment: http://www.arabidopsis.org/
[Term]
id: APO:P0000082
name: mitotic metaphase plate congression
def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis." [GOC:mah, ISBN:0815316194]
relationship: part_of APO:P0000002 ! mitotic sister chromatid segregation
xref: GO:0007080
[Term]
id: APO:R0000084
name: NCBI_gi
def: "NCBI databases" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/
[Term]
id: APO:P0000268
name: prophase
def: "Progression through prophase, the first stage of chromosome segregation in the cell cycle. Canonically, chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell." [GOC:ai]
relationship: part_of APO:P0000038 ! M phase
xref: GO:0051324
[Term]
id: APO:P0000132
name: female meiosis chromosome segregation
def: "The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai]
is_a: APO:P0000189 ! meiotic chromosome segregation
relationship: part_of APO:P0000120 ! female meiosis
xref: GO:0016321
[Term]
id: APO:P0000024
name: S-phase-specific transcription in mitotic cell cycle
def: "Any process that regulates transcription such that the target genes are transcribed during the S phase of the mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000013 ! S phase of mitotic cell cycle
synonym: "S-specific transcription in mitotic cell cycle" EXACT []
xref: GO:0000115
xref: Reactome:69241
[Term]
id: APO:U0000003
name: biopolymer
def: "A polymer, such as a protein, nucleic acid, or transcript, ocurring in, or formed by, living systems." [APO:ea]
is_a: APO:U0000001 ! continuant
synonym: "bio-polymer" EXACT [APO:ea]
[Term]
id: APO:P0000051
name: meiotic strand displacement
def: "During meiosis, the rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules." [GOC:elh, PMID:10357855]
relationship: part_of APO:P0000054 ! meiotic gene conversion
xref: GO:0000714
[Term]
id: APO:P0000219
name: positive regulation of transcription from RNA polymerase II promoter, mitotic
def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators]
is_a: APO:P0000207 ! positive regulation of transcription, mitotic
is_a: APO:P0000218 ! regulation of transcription from RNA polymerase II promoter, mitotic
synonym: "mitotic activation of transcription from Pol II promoter" EXACT []
synonym: "positive regulation of transcription from Pol II promoter, mitotic" EXACT []
xref: GO:0046022
[Term]
id: APO:R0000082
name: NC-IUBMB
def: "Nomenclature Committee of the International Union of Biochemistry and Molecular Biology" []
is_a: APO:R0000000 ! reference
comment: http://www.chem.qmw.ac.uk/iubmb/
[Term]
id: APO:B0000020
name: XRCC3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000103 ! meiosis
synonym: "ATXRCC3" EXACT []
synonym: "AT5G57450" EXACT []
xref: TAIR:gene:1006154138
[Term]
id: APO:R0000068
name: LocusID
def: "NCBI LocusLink ID" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/
[Term]
id: APO:R0000079
name: MO
def: "The MGED Ontology" []
is_a: APO:R0000000 ! reference
comment: http://mged.sourceforge.net/ontologies/MGEDontology.php
[Term]
id: APO:P0000207
name: positive regulation of transcription, mitotic
def: "Any process that activates or increases the frequency, rate or extent of transcription during mitosis." [GOC:go_curators]
is_a: APO:P0000206 ! regulation of transcription, mitotic
synonym: "mitotic activation of transcription" EXACT []
xref: GO:0045897
[Term]
id: APO:R0000056
name: IMGT_HLA
def: "Immunogenetics database, human MHC" []
is_a: APO:R0000000 ! reference
comment: http://www.ebi.ac.uk/imgt/hla
[Term]
id: APO:B0000071
name: AT3G50070.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F3A4.150" EXACT []
synonym: "AT3G50070" EXACT []
xref: TAIR:gene:2083127
[Term]
id: APO:B0000110
name: AT5G35520.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000069 ! mitosis
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "MOK9_12" EXACT []
synonym: "MOK9.12" EXACT []
synonym: "AT5G35520" EXACT []
xref: TAIR:gene:2169507
[Term]
id: APO:R0000074
name: MeSH
def: "Medical Subject Headings " []
is_a: APO:R0000000 ! reference
comment: http://www.nlm.nih.gov/mesh/2005/MBrowser.html
[Term]
id: APO:P0000180
name: meiotic DNA double-strand break formation
def: "The process of generating double-strand breaks at defined hotspots throughout the genome during meiosis I, which results in the initiation of meiotic recombination." [GOC:elh, GOC:jl, PMID:11529427]
relationship: part_of APO:P0000054 ! meiotic gene conversion
relationship: part_of APO:P0000108 ! meiotic recombination
xref: GO:0042138
[Term]
id: APO:P0000015
name: G2/M transition of mitotic cell cycle
def: "Progression from G2 phase to M phase of the mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000273 ! interphase of mitotic cell cycle
xref: GO:0000086
xref: Reactome:69275
[Term]
id: APO:P0000272
name: interphase of meiotic cell cycle
def: "Progression through interphase, the stage of cell cycle between successive rounds of meiosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [GOC:ai]
is_a: APO:P0000269 ! interphase
relationship: part_of APO:P0000265 ! meiotic cell cycle
xref: GO:0051328
[Term]
id: APO:R0000011
name: CGD_LOCUS
def: "Candida Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.candidagenome.org/
[Term]
id: APO:P0000215
name: positive regulation of progression through syncytial blastoderm mitotic cell cycle
def: "Any process that activates or increases the frequency, rate or extent of progression through the syncytial blastoderm mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000211 ! positive regulation of mitotic cell cycle, embryonic
is_a: APO:P0000126 ! regulation of progression through syncytial blastoderm mitotic cell cycle
synonym: "positive regulation of syncytial blastoderm cell cycle progression" EXACT []
xref: GO:0046004
[Term]
id: APO:P0000106
name: synapsis
def: "The side by side pairing and physical juxtaposition of homologous chromosomes at the metaphase plate." [GOC:elh]
relationship: part_of APO:P0000104 ! meiosis I
synonym: "homologous chromosome pairing at meiosis" EXACT []
xref: GO:0007129
[Term]
id: APO:P0000284
name: regulation of ubiquitin ligase activity during meiotic cell cycle
def: "Any process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle." [EC:6.3.2.19, GOC:ai]
relationship: part_of APO:P0000265 ! meiotic cell cycle
synonym: "regulation of ubiquitin-protein ligase activity during meiotic cell cycle" EXACT []
synonym: "meiotic anaphase-promoting complex regulator" NARROW []
synonym: "meiotic APC regulator" NARROW []
synonym: "meiotic SCF complex regulator" NARROW []
synonym: "meiotic ubiquitin ligase regulator" RELATED []
synonym: "meiotic ubiquitin-protein ligase regulator" RELATED []
xref: GO:0051440
[Term]
id: APO:P0000144
name: linear element formation
def: "Formation of a proteinaceous scaffold, related to the synaptonemal complex, found associated with S. pombe chromosomes during meiotic prophase." [GOC:mah, Sanger:jb]
relationship: part_of APO:P0000106 ! synapsis
xref: GO:0030999
[Term]
id: APO:R0000105
name: ProDom
def: "ProDom protein domain families automatically generated from Swiss-Prot and TrEMBL" []
is_a: APO:R0000000 ! reference
comment: http://prodes.toulouse.inra.fr/prodom/current/html/home.php
[Term]
id: APO:B0000008
name: SWI1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000068 ! female meiosis sister chromatid cohesion
relationship: participates_in APO:P0000067 ! male meiosis sister chromatid cohesion
relationship: participates_in APO:P0000108 ! meiotic recombination
synonym: "AT5G51330" EXACT []
synonym: "SWITCH1" EXACT []
synonym: "DYAD" EXACT []
xref: TAIR:gene:1005867672
[Term]
id: APO:R0000146
name: TRAIT
def: "TRAnscript Integrated Table, an integrated database of transcripts expressed in human skeletal muscle" []
is_a: APO:R0000000 ! reference
comment: http://muscle.cribi.unipd.it/
[Term]
id: APO:R0000075
name: MetaCyc
def: "The Metabolic Encyclopedia of metabolic and other pathways" []
is_a: APO:R0000000 ! reference
comment: http://metacyc.org/
[Term]
id: APO:B0000041
name: KRP7
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "F14J22_14" EXACT []
synonym: "KIP-RELATED PROTEIN 7" EXACT []
synonym: "F14J22.14" EXACT []
synonym: "AT1G49620" EXACT []
xref: TAIR:gene:2012185
[Term]
id: APO:R0000133
name: TGD
def: "Tetrahymena Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.ciliate.org/
[Term]
id: APO:R0000034
name: GDB
def: "Human Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.gdb.org/
[Term]
id: APO:P0000232
name: replication fork protection
def: "Processes preventing the collapse of stalled replication forks." [GOC:vw, PMID:14560029]
relationship: part_of APO:P0000160 ! intra-S DNA damage checkpoint
synonym: "replication fork maintenance" BROAD []
synonym: "replication fork stabilization" BROAD []
xref: GO:0048478
[Term]
id: APO:P0000117
name: male meiosis
def: "Meiosis in the male germline." [GOC:mah]
is_a: APO:P0000103 ! meiosis
xref: GO:0007140
[Term]
id: APO:P0000256
name: female meiosis chromosome separation
def: "The process by which paired chromosomes are physically detached from each other during female meiosis." [GOC:ai]
is_a: APO:P0000254 ! meiotic chromosome separation
is_a: APO:P0000132 ! female meiosis chromosome segregation
synonym: "chromosome separation during female meiosis" EXACT []
xref: GO:0051309
[Term]
id: APO:B0000105
name: AT5G45190.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT5G45190" EXACT []
synonym: "K18C1.7" EXACT []
synonym: "K18C1_7" EXACT []
xref: TAIR:gene:2153357
[Term]
id: APO:B0000127
name: MSH2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000188 ! negative regulation of meiotic recombination
synonym: "ATMSH2" EXACT []
synonym: "AT3G18524" EXACT []
synonym: "MUTS HOMOLOG 2" EXACT []
xref: TAIR:gene:3354686
[Term]
id: APO:P0000196
name: negative regulation of S phase of mitotic cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of S phase of mitotic cell cycle activity." [GOC:go_curators]
is_a: APO:P0000089 ! regulation of S phase of mitotic cell cycle
is_a: APO:P0000208 ! negative regulation of progression through mitotic cell cycle
xref: GO:0045749
[Term]
id: APO:P0000058
name: mitotic spindle organization and biogenesis
def: "The formation and maintenance of the microtubule spindle during a mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000037 ! mitotic cell cycle
synonym: "mitotic spindle organisation and biogenesis" EXACT []
synonym: "spindle organization and biogenesis during mitosis" EXACT []
xref: GO:0007052
[Term]
id: APO:P0000241
name: meiotic chromosome decondensation
def: "The alteration of chromosome structure from the condensed form they take on during meiosis to the relaxed disperse form they hold in resting cells." [GOC:ai]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
xref: GO:0051178
[Term]
id: APO:P0000279
name: meiosis II nuclear envelope reassembly
def: "The reformation of the nuclear envelope during meiosis II." [GOC:ai]
is_a: APO:P0000277 ! meiotic nuclear envelope reassembly
relationship: part_of APO:P0000112 ! meiosis II
xref: GO:0051335
[Term]
id: APO:B0000098
name: AT5G25380.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F18G18_15" EXACT []
synonym: "F18G18.15" EXACT []
synonym: "AT5G25380" EXACT []
xref: TAIR:gene:2145466
[Term]
id: APO:P0000041
name: re-entry into mitotic cell cycle after pheromone arrest
def: "The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated." [GOC:krc, PMID:9927449]
is_a: APO:P0000040 ! re-entry into mitotic cell cycle
synonym: "re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)" NARROW []
xref: GO:0000321
[Term]
id: APO:B0000015
name: CYCD1;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000010 ! G1 phase of mitotic cell cycle
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G70210" EXACT []
synonym: "F20P5.7" EXACT []
synonym: "F20P5_7" EXACT []
synonym: "CYCLIN D1;1" EXACT []
xref: TAIR:gene:1005867821
xref: TAIR:gene:2020662
[Term]
id: APO:R0000022
name: DDB_gene_name
def: "DictyBase" []
is_a: APO:R0000000 ! reference
comment: http://dictybase.org
[Term]
id: APO:B0000007
name: CDKB2;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000015 ! G2/M transition of mitotic cell cycle
synonym: "AT1G76540" EXACT []
xref: TAIR:gene:1005837028
[Term]
id: APO:P0000069
name: mitosis
def: "The division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:ma, ISBN:0198547684]
relationship: part_of APO:P0000016 ! M phase of mitotic cell cycle
xref: GO:0007067
[Term]
id: APO:P0000083
name: mitotic chromosome decondensation
def: "The alteration of chromosome structure from the condensed form they take on during mitosis to the relaxed disperse form they hold in resting cells." [GOC:ai]
relationship: part_of APO:P0000002 ! mitotic sister chromatid segregation
xref: GO:0007083
[Term]
id: APO:B0000090
name: CYCB1;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "CYCLIN B1;1" EXACT []
synonym: "F6G17.140" EXACT []
synonym: "F6G17_140" EXACT []
synonym: "AT4G37490" EXACT []
synonym: "CYCB1" EXACT []
xref: TAIR:gene:2126376
[Term]
id: APO:R0000032
name: FB
def: "FlyBase" []
is_a: APO:R0000000 ! reference
comment: http://flybase.bio.indiana.edu/
[Term]
id: APO:P0000075
name: activation of transcription on exit from mitosis, from RNA polymerase I promoter
is_a: APO:P0000074 ! activation of transcription on exit from mitosis
synonym: "activation of transcription on exit from mitosis, from Pol I promoter" EXACT []
xref: GO:0007073
[Term]
id: APO:B0000034
name: ATDMC1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000103 ! meiosis
synonym: "AT3G22880" EXACT []
synonym: "DMC1" EXACT []
synonym: "RECA-LIKE GENE" EXACT []
synonym: "ARLIM15" EXACT []
xref: TAIR:gene:1944702
[Term]
id: APO:P0000229
name: negative regulation of centrosome cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of the centrosome cycle." [GOC:ai]
is_a: APO:P0000228 ! regulation of centrosome cycle
xref: GO:0046606
[Term]
id: APO:R0000044
name: GOA
def: "GO Annotation at EBI" []
is_a: APO:R0000000 ! reference
comment: http://www.ebi.ac.uk/goa/
[Term]
id: APO:R0000018
name: COG_Cluster
def: "NCBI COG cluster" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/COG/
[Term]
id: APO:R0000096
name: PIR
def: "Protein Information Resource" []
is_a: APO:R0000000 ! reference
comment: http://pir.georgetown.edu/
[Term]
id: APO:P0000047
name: meiotic mismatch repair
def: "A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis." [GOC:elh, PMID:10357855]
relationship: part_of APO:P0000054 ! meiotic gene conversion
relationship: part_of APO:P0000108 ! meiotic recombination
xref: GO:0000710
[Term]
id: APO:B0000083
name: KRP2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "AT3G50630" EXACT []
synonym: "KIP-RELATED PROTEIN 2" EXACT []
synonym: "T3A5.10" EXACT []
xref: TAIR:gene:2101678
[Term]
id: APO:B0000116
name: EMB2284
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000197 ! positive regulation of S phase of mitotic cell cycle
synonym: "TILTED1" EXACT []
synonym: "EMBRYO DEFECTIVE 2284" EXACT []
synonym: "T23G18_21" EXACT []
synonym: "T23G18.21" EXACT []
synonym: "AT1G08260" EXACT []
synonym: "TIL1" EXACT []
synonym: "POL2A" EXACT []
xref: TAIR:gene:2199972
[Term]
id: APO:B0000111
name: AT5G50110.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "AT5G50110" EXACT []
synonym: "MPF21.12" EXACT []
synonym: "MPF21_12" EXACT []
xref: TAIR:gene:2170050
[Term]
id: APO:P0000035
name: diplotene
def: "Progression through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." [ISBN:0198547684]
relationship: part_of APO:P0000105 ! meiotic prophase I
xref: GO:0000240
[Term]
id: APO:P0000150
name: collapsed replication fork processing
def: "The process by which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired by a recombinational mechanism." [PMID:11459955, PMID:15367656]
relationship: part_of APO:P0000160 ! intra-S DNA damage checkpoint
xref: GO:0031297
[Term]
id: APO:P0000220
name: regulation of transcription from RNA polymerase III promoter, mitotic
def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators]
relationship: part_of APO:P0000206 ! regulation of transcription, mitotic
synonym: "mitotic regulation of transcription from Pol III promoter" EXACT []
synonym: "regulation of transcription from Pol III promoter, mitotic" EXACT []
xref: GO:0046023
[Term]
id: APO:R0000090
name: PANTHER
def: "Protein ANalysis THrough Evolutionary Relationships Classification System" []
is_a: APO:R0000000 ! reference
comment: http://www.pantherdb.org/
[Term]
id: APO:R0000005
name: AGRICOLA_NAL
def: "AGRICultural OnLine Access" []
is_a: APO:R0000000 ! reference
comment: http://agricola.nal.usda.gov/
[Term]
id: APO:B0000095
name: AT4G27650.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000103 ! meiosis
synonym: "AT4G27650" EXACT []
synonym: "T29A15_140" EXACT []
synonym: "T29A15.140" EXACT []
xref: TAIR:gene:2137731
[Term]
id: APO:P0000166
name: homologous chromosome orientation during meiosis
def: "The process by which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I." [PMID:15062096]
relationship: part_of APO:P0000183 ! meiotic metaphase I plate congression
synonym: "homologous chromosome orientation during meiosis I" EXACT []
xref: GO:0031619
[Term]
id: APO:P0000203
name: positive regulation of mitosis
def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators]
is_a: APO:P0000199 ! positive regulation of progression through cell cycle
is_a: APO:P0000087 ! regulation of mitosis
synonym: "mitogenic activity" NARROW []
xref: GO:0045840
[Term]
id: APO:R0000026
name: EcoCyc
def: "The Encyclopedia of E. coli metabolism" []
is_a: APO:R0000000 ! reference
comment: http://ecocyc.org/
[Term]
id: APO:R0000166
name: RI
def: "Roslin Institute" []
is_a: APO:R0000000 ! reference
comment: http://www.roslin.ac.uk/
[Term]
id: APO:P0000257
name: meiotic metaphase plate congression
def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis." [GOC:ai]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
synonym: "metaphase plate congression during meiosis" EXACT []
xref: GO:0051311
[Term]
id: APO:B0000018
name: RANGAP1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000003 ! M phase specific microtubule process
synonym: "AT3G63130" EXACT []
synonym: "RAN GTPASE ACTIVATING PROTEIN 1" EXACT []
xref: TAIR:gene:1005963835
[Term]
id: APO:P0000008
name: cell morphogenesis checkpoint
def: "A cell cycle checkpoint observed when aspects of polarity control are defective, which maintains coordination between the process of cellular morphogenesis and the nuclear events of the cell cycle. For example, in budding yeast cell-cycle delay or arrest is induced when aspects of bud formation are defective." [GOC:vw, PMID:14644188]
is_a: APO:P0000005 ! cell cycle checkpoint
xref: GO:0000078
[Term]
id: APO:P0000170
name: G2/M-specific regulation of cyclin-dependent protein kinase activity
def: "Any process that modulates the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah]
is_a: APO:P0000009 ! regulation of cyclin-dependent protein kinase activity
relationship: part_of APO:P0000015 ! G2/M transition of mitotic cell cycle
xref: GO:0031660
[Term]
id: APO:P0000001
name: mitotic spindle elongation
def: "Lengthening of the distance between poles of the mitotic spindle." [GOC:mah]
relationship: part_of APO:P0000058 ! mitotic spindle organization and biogenesis
synonym: "spindle elongation during mitosis" EXACT []
xref: GO:0000022
[Term]
id: APO:P0000090
name: mitotic metaphase/anaphase transition
def: "Progression from metaphase to anaphase during mitosis, triggered by the destruction of mitotic cyclins." [PMID:10465783]
relationship: part_of APO:P0000069 ! mitosis
xref: GO:0007091
xref: Reactome:68881
[Term]
id: APO:B0000026
name: MER3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000233 ! chiasma formation
relationship: participates_in APO:P0000108 ! meiotic recombination
synonym: "ROCK-N-ROLLERS" EXACT []
synonym: "RCK" EXACT []
synonym: "AT3G27730" EXACT []
xref: TAIR:gene:1008804540
[Term]
id: APO:P0000127
name: cyclin catabolism
def: "The chemical reactions and pathways resulting in the breakdown of cyclins, proteins whose levels in a cell varies markedly during the cell cycle, and which play key roles in regulating cell cycle phase transitions." [GOC:mah, http:cancerweb.ncl.ac.uk]
is_a: APO:P0000004 ! regulation of progression through cell cycle
synonym: "cyclin breakdown" EXACT []
synonym: "cyclin degradation" EXACT []
synonym: "degradation of cyclin" EXACT []
xref: GO:0008054
[Term]
id: APO:B0000006
name: CDKB2;2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000124 ! regulation of progression through mitotic cell cycle
synonym: "CYCLIN-DEPENDENT KINASE B2;2" EXACT []
synonym: "AT1G20930" EXACT []
xref: TAIR:gene:1005832604
[Term]
id: APO:P0000046
name: meiotic joint molecule formation
def: "The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule. These joint molecules contain Holliday junctions on either side of heteroduplex DNA." [GOC:elh, PMID:8521495]
relationship: part_of APO:P0000108 ! meiotic recombination
xref: GO:0000709
[Term]
id: APO:P0000145
name: septation initiation signaling
def: "The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the begining of cytokinesis and cell division by septum formation." [GOC:mah, GOC:vw]
is_a: APO:P0000173 ! regulation of contractile ring contraction during cytokinesis
synonym: "septation initiation network" EXACT []
synonym: "septation initiation signalling" EXACT []
synonym: "SIN" EXACT []
xref: GO:0031028
[Term]
id: APO:B0000005
name: CYCD3;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000010 ! G1 phase of mitotic cell cycle
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "CYCD3" EXACT []
synonym: "AT4G34160" EXACT []
synonym: "D3" EXACT []
synonym: "F28A23_80" EXACT []
synonym: "CYCLIN D3;1" EXACT []
synonym: "F28A23.80" EXACT []
xref: TAIR:gene:1005832139
xref: TAIR:gene:2124330
[Term]
id: APO:R0000151
name: UM-BBD_pathwayID
def: "The University of Minnesota Biocatalysis/Biodegradation Database" []
is_a: APO:R0000000 ! reference
comment: http://umbbd.ahc.umn.edu/index.html
[Term]
id: APO:R0000053
name: HAMAP
def: "High-quality Automated and Manual Annotation of microbial Proteomes" []
is_a: APO:R0000000 ! reference
comment: http://us.expasy.org/sprot/hamap/
[Term]
id: APO:P0000301
name: meiotic sister chromatid separation
def: "The process by which sister chromatids are physically detached from each other during meiosis." [GOC:ai, PMID:14730319, PMID:16325576]
is_a: APO:P0000254 ! meiotic chromosome separation
xref: GO:0051757
[Term]
id: APO:R0000102
name: Pompep
def: "Schizosaccharomyces pombe protein data" []
is_a: APO:R0000000 ! reference
comment: ftp://ftp.sanger.ac.uk/pub/yeast/pombe/Protein_data/
[Term]
id: APO:B0000061
name: CYCP3;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G45080" EXACT []
synonym: "T14P1.11" EXACT []
xref: TAIR:gene:2055551
[Term]
id: APO:P0000186
name: mitotic spindle stabilization
def: "Maintenance of spindle integrity during M phase of mitosis." [GOC:go_curators]
relationship: part_of APO:P0000058 ! mitotic spindle organization and biogenesis
xref: GO:0043148
[Term]
id: APO:B0000084
name: CYCP3;2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "T8B10.210" EXACT []
synonym: "AT3G60550" EXACT []
xref: TAIR:gene:2103390
[Term]
id: APO:B0000032
name: ATXR5
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000294 ! regulation of cell cycle
synonym: "AT5G09790" EXACT []
xref: TAIR:gene:1010392007
[Term]
id: APO:P0000089
name: regulation of S phase of mitotic cell cycle
def: "Any process that modulates the frequency, rate or extent of the progression through the S phase of mitotic cell cycle." [GOC:go_curators]
relationship: part_of APO:P0000013 ! S phase of mitotic cell cycle
relationship: part_of APO:P0000124 ! regulation of progression through mitotic cell cycle
xref: GO:0007090
[Term]
id: APO:R0000145
name: TIGR_TIGRFAMS
def: "The Institute for Genomic Research, TIGRFAMs HMM collection" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/
[Term]
id: APO:P0000036
name: diakinesis
def: "Progression through the final stage of prophase I in meiosis; the transition to meiotic metaphase I." [ISBN:0198547684]
relationship: part_of APO:P0000105 ! meiotic prophase I
xref: GO:0000241
[Term]
id: APO:P0000216
name: regulation of transcription from RNA polymerase I promoter, mitotic
def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators]
relationship: part_of APO:P0000206 ! regulation of transcription, mitotic
synonym: "mitotic regulation of transcription from Pol I promoter" EXACT []
synonym: "regulation of transcription from Pol I promoter, mitotic" EXACT []
xref: GO:0046017
[Term]
id: APO:P0000266
name: anaphase
def: "Progression through anaphase, the third stage of chromosome segregation in the cell cycle. Canonically, sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle." [http:www.onelook.com]
relationship: part_of APO:P0000038 ! M phase
xref: GO:0051322
[Term]
id: APO:P0000239
name: meiosis II nuclear envelope disassembly
def: "The controlled breakdown of the nuclear envelope during the second division of meiosis." [GOC:bf]
is_a: APO:P0000237 ! meiotic nuclear envelope disassembly
relationship: part_of APO:P0000112 ! meiosis II
synonym: "meiosis II nuclear envelope breakdown" EXACT []
synonym: "meiosis II nuclear envelope degradation" EXACT []
xref: GO:0051080
[Term]
id: APO:B0000134
name: CUL3A
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "T24P13.25" EXACT []
synonym: "AT1G26830" EXACT []
synonym: "ATCUL3" EXACT []
synonym: "ATCUL3A" EXACT []
synonym: "CUL3" EXACT []
xref: TAIR:gene:3435278
[Term]
id: APO:P0000093
name: mitotic spindle checkpoint
def: "A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly)." [GOC:rn, PMID:12360190]
is_a: APO:P0000092 ! mitotic checkpoint
is_a: APO:P0000164 ! spindle checkpoint
synonym: "Mad2-dependent checkpoint" NARROW []
xref: GO:0007094
xref: Reactome:69618
[Term]
id: APO:P0000139
name: regulation of mitotic metaphase/anaphase transition
def: "Any process that modulates the frequency, rate or extent of the onset of anaphase (chromosome movement) in the mitotic cell cycle." [GOC:mah]
is_a: APO:P0000087 ! regulation of mitosis
relationship: part_of APO:P0000090 ! mitotic metaphase/anaphase transition
xref: GO:0030071
[Term]
id: APO:B0000145
name: CYCB2;3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G20610" EXACT []
synonym: "F5M15.6" EXACT []
synonym: "Cyclin B2;3" EXACT []
xref: TAIR:gene:3691012
[Term]
id: APO:P0000122
name: meiotic recombination nodule assembly
def: "The assembly of small, electron dense structures in association with meiotic chromosomes." [GOC:jl, PMID:9334324]
is_a: APO:P0000044 ! meiotic DNA recombinase assembly
xref: GO:0007146
[Term]
id: APO:P0000231
name: suppression by virus of host cell cycle arrest
def: "Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur." [PMID:9371605]
is_a: APO:P0000137 ! modification by virus of host cell cycle regulation
synonym: "negative regulation by virus of cell cycle arrest" EXACT []
synonym: "viral inhibition of cell cycle arrest" EXACT []
xref: GO:0046792
[Term]
id: APO:P0000293
name: meiotic recombination checkpoint
def: "A checkpoint during late prophase I (pachytene) which prevents segregation of homologous chromosomes until recombination is completed and ensures proper distribution of the genetic material to the gametes." [PMID:14718568]
is_a: APO:P0000200 ! negative regulation of meiosis
is_a: APO:P0000005 ! cell cycle checkpoint
relationship: part_of APO:P0000105 ! meiotic prophase I
synonym: "pachytene checkpoint" EXACT []
xref: GO:0051598
[Term]
id: APO:P0000248
name: meiotic spindle midzone assembly
def: "The formation of the meiotic spindle midzone, the area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap." [GOC:ai]
relationship: part_of APO:P0000242 ! meiotic spindle assembly
synonym: "meiotic spindle midzone biogenesis" EXACT []
synonym: "meiotic spindle midzone formation" EXACT []
synonym: "spindle midzone assembly during meiosis" EXACT []
synonym: "spindle midzone biogenesis during meiosis" EXACT []
synonym: "spindle midzone formation during meiosis" EXACT []
xref: GO:0051257
[Term]
id: APO:P0000178
name: regulation of meiosis
def: "Any process that modulates the frequency, rate or extent of meiosis, the process by which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma]
relationship: part_of APO:P0000103 ! meiosis
xref: GO:0040020
[Term]
id: APO:U0000007
name: interaction
def: "Any reciprocal or mutual action or effect between two continuants." [APO:ea]
is_a: APO:U0000002 ! process
[Term]
id: APO:B0000010
name: ICK6
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "AT5G48820" EXACT []
synonym: "KRP3" EXACT []
xref: TAIR:gene:1005867752
[Term]
id: APO:R0000065
name: KEGG_PATHWAY
def: "KEGG Pathways Database" []
is_a: APO:R0000000 ! reference
comment: http://www.genome.ad.jp/kegg/docs/upd_pathway.html
[Term]
id: APO:R0000122
name: SGD_LOCUS
def: "Saccharomyces Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.yeastgenome.org/
[Term]
id: APO:P0000062
name: female meiotic spindle assembly (sensu Metazoa)
def: "The formation of the spindle during a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
is_a: APO:P0000242 ! meiotic spindle assembly
relationship: part_of APO:P0000120 ! female meiosis
xref: GO:0007056
[Term]
id: APO:P0000289
name: negative regulation of progression through meiotic cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai]
is_a: APO:P0000198 ! negative regulation of progression through cell cycle
is_a: APO:P0000287 ! regulation of progression through meiotic cell cycle
synonym: "negative regulation of meiotic cell cycle progression" EXACT []
xref: GO:0051447
[Term]
id: APO:B0000062
name: CYCB2;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "T19E12_4" EXACT []
synonym: "AT2G17620" EXACT []
synonym: "Cyclin B2;1" EXACT []
synonym: "T19E12.4" EXACT []
xref: TAIR:gene:2057242
[Term]
id: APO:P0000116
name: meiotic telophase II
def: "Progression through telophase of meiosis II; analogous to mitotic telophase." [GOC:mah]
is_a: APO:P0000270 ! telophase
relationship: part_of APO:P0000112 ! meiosis II
xref: GO:0007139
[Term]
id: APO:P0000056
name: cell cycle
def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators]
is_a: APO:U0000002 ! process
synonym: "cell-division cycle" EXACT []
xref: GO:0007049
[Term]
id: APO:R0000073
name: MEROPS_fam
def: "MEROPS: The Peptidase Database" []
is_a: APO:R0000000 ! reference
comment: http://merops.sanger.ac.uk/
[Term]
id: APO:B0000040
name: AT1G35440.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G35440" EXACT []
synonym: "F12A4_13" EXACT []
synonym: "F12A4.13" EXACT []
xref: TAIR:gene:2008697
[Term]
id: APO:U0000010
name: complex
def: "Any distinct chemical species in which two or more identical or nonidentical chemical species are associated." [APO:ea]
is_a: APO:U0000001 ! continuant
[Term]
id: APO:P0000028
name: septin checkpoint
def: "A cell cycle checkpoint that detects septin defects and responds by inhibiting the mitotic CDK. In Saccharomyces cerevisiae, correct formation of a functional septin cytoskeleton permits the cell to switch to isotropic bud growth and the onset of mitotic chromosome segregation. In the presence of septin defects, the mitotic CDK is inhibited and both the switch to isotropic bud growth and the onset of mitotic chromosome segregation is delayed." [PMID:9925642]
is_a: APO:P0000005 ! cell cycle checkpoint
xref: GO:0000135
[Term]
id: APO:B0000052
name: CYCA3;4
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G47230" EXACT []
synonym: "CYCLIN A3;4" EXACT []
synonym: "F8G22.5" EXACT []
synonym: "F8G22_5" EXACT []
xref: TAIR:gene:2036755
[Term]
id: APO:P0000278
name: meiosis I nuclear envelope reassembly
def: "The reformation of the nuclear envelope during meiosis I." [GOC:ai]
is_a: APO:P0000277 ! meiotic nuclear envelope reassembly
relationship: part_of APO:P0000104 ! meiosis I
xref: GO:0051334
[Term]
id: APO:R0000028
name: ECOGENE_G
def: "The EcoGene Database of Escherichia coli Sequence and Function" []
is_a: APO:R0000000 ! reference
comment: http://www.ecogene.org/
[Term]
id: APO:P0000128
name: meiotic G2/MI transition
def: "Progression from meiotic prophase to metaphase I." [PMID:15088480]
relationship: part_of APO:P0000104 ! meiosis I
xref: GO:0008315
[Term]
id: APO:P0000274
name: G1 phase of meiotic cell cycle
def: "Progression through G1 phase, one of two 'gap' phases in the meiotic cell cycle; G1 is the interval between the completion of meiosis and the beginning of DNA synthesis." [GOC:ai]
is_a: APO:P0000262 ! G1 phase
relationship: part_of APO:P0000272 ! interphase of meiotic cell cycle
xref: GO:0051330
[Term]
id: APO:P0000061
name: male meiosis II spindle assembly (sensu Metazoa)
def: "The formation of the spindle during meiosis I of a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
is_a: APO:P0000059 ! male meiotic spindle assembly (sensu Metazoa)
relationship: part_of APO:P0000119 ! male meiosis II
xref: GO:0007055
[Term]
id: APO:B0000119
name: CUL3B
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "AT1G69670" EXACT []
synonym: "T6C23_13" EXACT []
synonym: "ATCUL3B" EXACT []
synonym: "T6C23.13" EXACT []
xref: TAIR:gene:2205019
[Term]
id: APO:P0000271
name: M phase of meiotic cell cycle
def: "Progression through M phase, the part of the meiotic cell cycle during which meiosis and cytokinesis take place." [GOC:ai]
is_a: APO:P0000038 ! M phase
relationship: part_of APO:P0000265 ! meiotic cell cycle
xref: GO:0051327
[Term]
id: APO:R0000124
name: SMART
def: "Simple Modular Architecture Research Tool" []
is_a: APO:R0000000 ! reference
comment: http://smart.embl-heidelberg.de/
[Term]
id: APO:P0000285
name: positive regulation of ubiquitin ligase activity during meiotic cell cycle
def: "Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai]
is_a: APO:P0000284 ! regulation of ubiquitin ligase activity during meiotic cell cycle
synonym: "activation of ubiquitin ligase activity during meiotic cell cycle" NARROW []
synonym: "meiotic SCF complex activator" NARROW []
synonym: "meiotic ubiquitin ligase activator" NARROW []
xref: GO:0051441
[Term]
id: APO:P0000263
name: G2 phase
def: "Progression through G2 phase, one of two 'gap' phases in the cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis)." [GOC:ai]
relationship: part_of APO:P0000269 ! interphase
xref: GO:0051319
[Term]
id: APO:B0000128
name: ATM
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000103 ! meiosis
relationship: participates_in APO:P0000108 ! meiotic recombination
synonym: "AT3G48190" EXACT []
synonym: "ATAXIA-TELANGIECTASIA MUTATED" EXACT []
synonym: "ATATM" EXACT []
xref: TAIR:gene:3354887
[Term]
id: APO:P0000208
name: negative regulation of progression through mitotic cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000198 ! negative regulation of progression through cell cycle
is_a: APO:P0000124 ! regulation of progression through mitotic cell cycle
synonym: "negative regulation of mitotic cell cycle" EXACT []
synonym: "negative regulation of mitotic cell cycle progression" EXACT []
xref: GO:0045930
[Term]
id: APO:P0000098
name: mitotic centrosome separation
def: "Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle." [ISBN:0815316194]
is_a: APO:P0000252 ! centrosome separation
xref: GO:0007100
[Term]
id: APO:R0000132
name: TC
def: "The Transport Protein Database" []
is_a: APO:R0000000 ! reference
comment: http://tcdb.ucsd.edu/tcdb/
[Term]
id: APO:P0000059
name: male meiotic spindle assembly (sensu Metazoa)
def: "The formation of the spindle during a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
is_a: APO:P0000242 ! meiotic spindle assembly
relationship: part_of APO:P0000117 ! male meiosis
xref: GO:0007053
[Term]
id: APO:P0000153
name: cytokinesis, contractile ring maintenance
def: "Maintenance of the contractile ring in response to the cytokinesis checkpoint, i.e. when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures." [GOC:vw]
relationship: part_of APO:P0000152 ! cytokinesis checkpoint
xref: GO:0031566
[Term]
id: APO:P0000165
name: spindle orientation checkpoint
def: "A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. The result is a cell cycle delay, usually in mitosis, until errors are corrected." [GOC:clt, PMID:14616062]
is_a: APO:P0000005 ! cell cycle checkpoint
synonym: "SOC" EXACT []
synonym: "spindle position checkpoint" EXACT []
synonym: "SPOC" EXACT []
xref: GO:0031578
[Term]
id: APO:B0000036
name: MAD1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000112 ! meiosis II
synonym: "MALE GAMETOPHYTIC DEFECTIVE 1" EXACT []
xref: TAIR:gene:1945204
[Term]
id: APO:P0000081
name: mitotic chromosome movement towards spindle pole
def: "The directed movement of chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during mitosis." [GOC:ai]
relationship: part_of APO:P0000002 ! mitotic sister chromatid segregation
synonym: "chromosome migration to spindle pole during mitosis" EXACT []
synonym: "chromosome movement towards spindle pole during mitosis" EXACT []
synonym: "mitotic chromosome movement to spindle pole" EXACT []
synonym: "mitotic sister chromosome movement towards spindle pole" EXACT []
synonym: "sister chromosome movement towards spindle pole during mitosis" EXACT []
synonym: "mitotic chromosome movement" BROAD []
xref: GO:0007079
xref: GO:0007082
[Term]
id: APO:R0000025
name: EchoBASE
def: "EchoBASE post-genomic database for Escherichia coli" []
is_a: APO:R0000000 ! reference
comment: http://www.ecoli-york.org/
[Term]
id: APO:R0000117
name: RESID
def: "RESID Database of Protein Modifications" []
is_a: APO:R0000000 ! reference
comment: ftp://ftp.ncifcrf.gov/pub/users/residues/
[Term]
id: APO:B0000153
name: ICK2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "AT3G50630" EXACT []
synonym: "KRP2" EXACT []
xref: TAIR:gene:3715331
[Term]
id: APO:P0000302
name: homologous chromosome movement towards spindle pole during meiosis I
def: "The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I." [GOC:ai]
is_a: APO:P0000134 ! meiotic chromosome movement towards spindle pole
relationship: part_of APO:P0000191 ! homologous chromosome segregation
synonym: "meiosis I, homologous chromosome movement towards spindle pole" EXACT []
xref: GO:0051758
[Term]
id: APO:R0000081
name: NASC_code
def: "Nottingham Arabidopsis Stock Centre Seeds Database" []
is_a: APO:R0000000 ! reference
comment: http://arabidopsis.info
[Term]
id: APO:R0000045
name: GOC
def: "Gene Ontology Consortium" []
is_a: APO:R0000000 ! reference
comment: http://www.geneontology.org/
[Term]
id: APO:P0000292
name: anaphase-promoting complex activation during meiotic cell cycle
def: "Any process that initiatiates the ubiquitin ligase activity of the anaphase-promoting complex during the meiotic cell cycle." [GOC:mah, PMID:10871297]
is_a: APO:P0000285 ! positive regulation of ubiquitin ligase activity during meiotic cell cycle
synonym: "activation of ubiquitin ligase activity of anaphase promoting complex during meiotic cell cycle" EXACT []
synonym: "activation of ubiquitin ligase activity of anaphase-promoting complex during meiotic cell cycle" EXACT []
synonym: "activation of ubiquitin ligase activity of APC during meiotic cell cycle" EXACT []
synonym: "anaphase promoting complex activation during meiotic cell cycle" EXACT []
synonym: "APC activation during meiotic cell cycle" EXACT []
synonym: "meiotic anaphase promoting complex activation" EXACT []
synonym: "meiotic APC activation" EXACT []
synonym: "meiotic anaphase promoting complex activator" NARROW []
synonym: "meiotic anaphase-promoting complex activator" NARROW []
synonym: "meiotic APC activator" NARROW []
xref: GO:0051487
[Term]
id: APO:R0000010
name: CGD
def: "Candida Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.candidagenome.org/
[Term]
id: APO:B0000045
name: AT1G02980.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "F22D16.2" EXACT []
synonym: "F22D16_2" EXACT []
synonym: "AT1G02980" EXACT []
xref: TAIR:gene:2024754
[Term]
id: APO:P0000007
name: DNA damage checkpoint
def: "A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds." [PMID:11891124]
is_a: APO:P0000157 ! DNA integrity checkpoint
synonym: "DNA damage response, signal transduction resulting in cell cycle arrest" NARROW []
xref: GO:0000077
[Term]
id: APO:B0000033
name: ATXR6
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000294 ! regulation of cell cycle
synonym: "AT5G24330" EXACT []
xref: TAIR:gene:1010392008
[Term]
id: APO:B0000102
name: EMB2656
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000078 ! mitotic chromosome condensation
synonym: "K12B20_9" EXACT []
synonym: "AT5G37630" EXACT []
synonym: "EMBRYO DEFECTIVE 2656" EXACT []
synonym: "EMBRYO DEFECTIVE 2217" EXACT []
synonym: "K12B20.9" EXACT []
xref: TAIR:gene:2151763
[Term]
id: APO:B0000133
name: AT1G27630.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G27630" EXACT []
synonym: "T22C5.8" EXACT []
xref: TAIR:gene:3433100
[Term]
id: APO:R0000154
name: VIDA
def: "Virus Database at University College London" []
is_a: APO:R0000000 ! reference
comment: http://www.biochem.ucl.ac.uk/bsm/virus_database/VIDA.html
[Term]
id: APO:P0000177
name: establishment of mitotic spindle localization
def: "The directed movement of the mitotic spindle to a specific location in the cell." [GOC:ai]
relationship: part_of APO:P0000037 ! mitotic cell cycle
synonym: "mitotic spindle positioning" EXACT []
synonym: "mitotic spindle positioning or orientation" EXACT []
synonym: "spindle positioning during mitosis" EXACT []
synonym: "mitotic spindle positioning (sensu Fungi)" NARROW []
synonym: "mitotic spindle positioning (sensu Saccharomyces)" NARROW []
synonym: "mitotic spindle positioning and orientation (sensu Saccharomyces)" NARROW []
synonym: "mitotic spindle positioning or orientation (sensu Fungi)" NARROW []
xref: GO:0040001
xref: GO:0018986
xref: GO:0030605
xref: GO:0030606
xref: GO:0030608
xref: GO:0030610
[Term]
id: APO:P0000011
name: G1/S transition of mitotic cell cycle
def: "Progression from G1 phase to S phase of the mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000273 ! interphase of mitotic cell cycle
xref: GO:0000082
xref: Reactome:69206
[Term]
id: APO:R0000023
name: DDB_REF
def: "DictyBase literature references" []
is_a: APO:R0000000 ! reference
comment: http://dictybase.org
[Term]
id: APO:B0000096
name: AT5G10440.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F12B17_210" EXACT []
synonym: "F12B17.210" EXACT []
synonym: "AT5G10440" EXACT []
xref: TAIR:gene:2142503
[Term]
id: APO:B0000107
name: AT5G49880.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000092 ! mitotic checkpoint
synonym: "K9P8.2" EXACT []
synonym: "K9P8_2" EXACT []
synonym: "AT5G49880" EXACT []
xref: TAIR:gene:2158803
[Term]
id: APO:R0000029
name: EMBL
def: "International Nucleotide Sequence Database Collaboration, comprising EMBL-EBI International Nucleotide Sequence Data Library (EMBL-Bank), DNA DataBank of Japan (DDBJ), and NCBI GenBank" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/Genbank/
[Term]
id: APO:B0000085
name: AT4G37630.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT4G37630" EXACT []
synonym: "F19F18.120" EXACT []
synonym: "F19F18_120" EXACT []
xref: TAIR:gene:2120080
[Term]
id: APO:R0000066
name: LIFEdb
def: "LIFEdb, a database for the integration and dissemination of functional data" []
is_a: APO:R0000000 ! reference
comment: http://www.lifedb.de/
[Term]
id: APO:B0000149
name: CYCB1;3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "CYCLIN B1;3" EXACT []
synonym: "AT3G11520" EXACT []
synonym: "CYC2" EXACT []
xref: TAIR:gene:3713830
[Term]
id: APO:R0000072
name: MEROPS
def: "MEROPS - the Peptidase Database" []
is_a: APO:R0000000 ! reference
comment: http://merops.sanger.ac.uk/
[Term]
id: APO:B0000093
name: CYCB2;2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F8D20_130" EXACT []
synonym: "Cyclin B2;2" EXACT []
synonym: "AT4G35620" EXACT []
synonym: "F8D20.130" EXACT []
xref: TAIR:gene:2127947
[Term]
id: APO:P0000065
name: male meiosis chromosome segregation
def: "The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male." [GOC:ai]
is_a: APO:P0000189 ! meiotic chromosome segregation
relationship: part_of APO:P0000117 ! male meiosis
xref: GO:0007060
[Term]
id: APO:B0000141
name: DPB
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000011 ! G1/S transition of mitotic cell cycle
synonym: "DPB TRANSCRIPTION FACTOR" EXACT []
synonym: "AT5G03415" EXACT []
synonym: "ATDPB" EXACT []
xref: TAIR:gene:3685842
[Term]
id: APO:B0000125
name: ICK1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "KIP-RELATED PROTEIN 1" EXACT []
synonym: "AT2G23430" EXACT []
synonym: "KRP1" EXACT []
synonym: "CYCLIN-DEPENDENT KINASE INHIBITOR PROTEIN" EXACT []
xref: TAIR:gene:3354098
[Term]
id: APO:P0000092
name: mitotic checkpoint
def: "A signal transduction-based surveillance mechanism that ensures accurate chromosome segregation by preventing entry into, passage through and exit from mitosis. Events that may be monitored include the formation of a correctly assembled spindle, the position of the spindle pole (centrosome) and the orientation of the spindle and cellular morphogenesis." [GOC:rn, PMID:12360190]
is_a: APO:P0000087 ! regulation of mitosis
is_a: APO:P0000005 ! cell cycle checkpoint
xref: GO:0007093
xref: Reactome:73676
[Term]
id: APO:U0000008
name: pathway
def: "A chain of interactions undergone by a given biopolymer or molecular entity in a particular organism." [APO:ea]
is_a: APO:U0000002 ! process
[Term]
id: APO:P0000163
name: G2/M transition checkpoint
def: "Any cell cycle checkpoint that blocks entry into M phase." [GOC:mah]
is_a: APO:P0000005 ! cell cycle checkpoint
synonym: "G2/M checkpoint" EXACT []
xref: GO:0031576
[Term]
id: APO:R0000020
name: COG_Pathway
def: "NCBI COG pathway" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/COG/
[Term]
id: APO:P0000021
name: mitotic anaphase B
def: "Progression through anaphase B, the part of mitotic anaphase in which the polar microtubules elongate and the two poles of the spindle move farther apart." [ISBN:0815316194]
is_a: APO:P0000019 ! mitotic anaphase
xref: GO:0000092
[Term]
id: APO:P0000057
name: cell cycle arrest
def: "Any process by which progression through the cell cycle is halted during one of the normal phases (G1, S, G2, M)." [GOC:mah]
is_a: APO:P0000198 ! negative regulation of progression through cell cycle
synonym: "arrest of cell cycle progression" EXACT []
synonym: "cessation of cell cycle" EXACT []
synonym: "termination of cell cycle" EXACT []
xref: GO:0007050
[Term]
id: APO:R0000059
name: InterPro
def: "The InterPro database of protein domains and motifs" []
is_a: APO:R0000000 ! reference
comment: http://www.ebi.ac.uk/interpro/
[Term]
id: APO:P0000230
name: positive regulation of centrosome cycle
def: "Any process that activates or increases the frequency, rate or extent of the centrosome cycle." [GOC:ai]
is_a: APO:P0000228 ! regulation of centrosome cycle
xref: GO:0046607
[Term]
id: APO:P0000138
name: actin filament reorganization during cell cycle
def: "Rearrangement of the spatial distribution of actin filaments and associated proteins that accompanies progression of the cell cycle." [GOC:mah]
relationship: part_of APO:P0000056 ! cell cycle
synonym: "actin filament reorganisation during cell cycle" EXACT []
xref: GO:0030037
[Term]
id: APO:B0000158
name: RNR2B
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT5G40942" EXACT []
xref: TAIR:gene:504952749
[Term]
id: APO:P0000037
name: mitotic cell cycle
def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, in which a cell is duplicated without changing ploidy; comprises four successive phases called G1, S, G2, and M." [GOC:mah, ISBN:0815316194]
is_a: APO:P0000056 ! cell cycle
xref: GO:0000278
xref: Reactome:69278
[Term]
id: APO:P0000064
name: female meiosis II spindle assembly (sensu Metazoa)
def: "The formation of the spindle during meiosis II of a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
is_a: APO:P0000062 ! female meiotic spindle assembly (sensu Metazoa)
relationship: part_of APO:P0000123 ! female meiosis II
xref: GO:0007058
[Term]
id: APO:P0000088
name: traversing start control point of mitotic cell cycle
def: "Passage through a cell cycle control point late in G1 phase of the mitotic cell cycle just before entry into S phase; in most organisms studied, including budding yeast and animal cells, passage through start normally commits the cell to progressing through the entire cell cycle." [GOC:mah, ISBN:0815316194]
is_a: APO:P0000124 ! regulation of progression through mitotic cell cycle
relationship: part_of APO:P0000010 ! G1 phase of mitotic cell cycle
synonym: "G1 checkpoint" RELATED []
xref: GO:0007089
xref: GO:0000081
[Term]
id: APO:P0000147
name: negative regulation of septation initiation signaling
def: "Any process that stops, prevents or reduces the frequency, rate or extent of septation initiation signaling." [GOC:mah]
is_a: APO:P0000146 ! regulation of septation initiation signaling
synonym: "negative regulation of septation initiation network" EXACT []
synonym: "negative regulation of septation initiation signalling" EXACT []
xref: GO:0031030
[Term]
id: APO:R0000157
name: WB_REF
def: "WormBase, database of nematode biology" []
is_a: APO:R0000000 ! reference
comment: http://www.wormbase.org/
[Term]
id: APO:P0000121
name: female meiosis I
def: "The first meiotic division in the female germline." [GOC:mah]
relationship: part_of APO:P0000120 ! female meiosis
xref: GO:0007144
[Term]
id: APO:P0000053
name: negative regulation of exit from mitosis
def: "Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:rn]
is_a: APO:P0000095 ! regulation of exit from mitosis
xref: GO:0001100
[Term]
id: APO:B0000151
name: ASK9
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000124 ! regulation of progression through mitotic cell cycle
synonym: "AT3G21850" EXACT []
synonym: "ARABIDOPSIS SKP1-LIKE 9" EXACT []
xref: TAIR:gene:3714889
[Term]
id: APO:R0000002
name: AGI_LocusCode
def: "Arabidopsis Genome Initiative (TAIR, TIGR, MIPS)" []
is_a: APO:R0000000 ! reference
comment: http://www.arabidopsis.org
[Term]
id: APO:P0000249
name: establishment of meiotic spindle localization
def: "The directed movement of the meiotic spindle to a specific location in the cell." [GOC:ai]
relationship: part_of APO:P0000265 ! meiotic cell cycle
synonym: "meiotic spindle positioning" EXACT []
synonym: "spindle positioning during meiosis" EXACT []
xref: GO:0051295
[Term]
id: APO:R0000119
name: RNAmods
def: "The RNA Modification Database" []
is_a: APO:R0000000 ! reference
comment: http://medlib.med.utah.edu/RNAmods/
[Term]
id: APO:P0000020
name: mitotic anaphase A
def: "Progression through anaphase A, the part of mitotic anaphase in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles." [ISBN:0815316194]
is_a: APO:P0000019 ! mitotic anaphase
xref: GO:0000091
[Term]
id: APO:P0000242
name: meiotic spindle assembly
def: "The formation of the spindle during a meiotic cell cycle." [GOC:ai]
is_a: APO:P0000029 ! meiotic spindle organization and biogenesis
synonym: "meiotic spindle biogenesis" EXACT []
synonym: "meiotic spindle formation" EXACT []
synonym: "spindle assembly during meiosis" EXACT []
synonym: "spindle biogenesis during meiosis" EXACT []
synonym: "spindle formation during meiosis" EXACT []
synonym: "bipolar spindle formation" BROAD []
xref: GO:0051226
[Term]
id: APO:B0000121
name: AT1G34460.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G34460" EXACT []
synonym: "F12K21.22" EXACT []
synonym: "F12K21_22" EXACT []
xref: TAIR:gene:2806634
[Term]
id: APO:P0000095
name: regulation of exit from mitosis
def: "Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity." [GOC:rn]
is_a: APO:P0000087 ! regulation of mitosis
xref: GO:0007096
[Term]
id: APO:P0000304
name: meiotic sister chromatid cohesion, arms
def: "The joining of the sister chromatids of a replicated chromosome along the length of the chromosome arms that occurs during meiosis." [PMID:14730319, PMID:16325576]
relationship: part_of APO:P0000240 ! meiotic sister chromatid cohesion
synonym: "meiotic sister chromatid cohesion along arms" EXACT []
synonym: "sister chromatid cohesion along arms at meiosis I" EXACT []
xref: GO:0051760
[Term]
id: APO:P0000129
name: regulation of progression through embryonic mitotic cell cycle
def: "Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo." [GOC:go_curators]
is_a: APO:P0000124 ! regulation of progression through mitotic cell cycle
relationship: part_of APO:P0000193 ! mitotic cell cycle, embryonic
synonym: "control of embryonic mitotic cell cycle progression" EXACT []
synonym: "embryonic mitotic cell cycle control" EXACT []
synonym: "embryonic mitotic cell cycle modulation" EXACT []
synonym: "embryonic mitotic cell cycle regulation" EXACT []
synonym: "modulation of embryonic mitotic cell cycle progression" EXACT []
synonym: "regulation of embryonic mitotic cell cycle" EXACT []
synonym: "regulation of embryonic mitotic cell cycle progression" EXACT []
synonym: "regulation of mitotic cell cycle, embryonic" EXACT []
synonym: "embryonic mitotic cell cycle regulator" RELATED []
xref: GO:0009794
[Term]
id: APO:P0000225
name: regulation of mitotic centrosome separation
def: "Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis." [GOC:ai]
is_a: APO:P0000228 ! regulation of centrosome cycle
relationship: part_of APO:P0000098 ! mitotic centrosome separation
xref: GO:0046602
[Term]
id: APO:P0000286
name: negative regulation of ubiquitin ligase activity during meiotic cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai]
is_a: APO:P0000284 ! regulation of ubiquitin ligase activity during meiotic cell cycle
synonym: "anaphase promoting complex inhibition during meiotic cell cycle" NARROW []
synonym: "anaphase-promoting complex inhibition during meiotic cell cycle" NARROW []
synonym: "APC inhibition during meiotic cell cycle" NARROW []
synonym: "meiotic anaphase promoting complex inhibition" NARROW []
synonym: "meiotic anaphase promoting complex inhibitor" NARROW []
synonym: "meiotic anaphase-promoting complex inhibition" NARROW []
synonym: "meiotic anaphase-promoting complex inhibitor" NARROW []
synonym: "meiotic APC inhibition" NARROW []
synonym: "meiotic APC inhibitor" NARROW []
synonym: "meiotic SCF complex inhibitor" NARROW []
synonym: "meiotic ubiquitin ligase inhibitor" NARROW []
xref: GO:0051442
[Term]
id: APO:B0000114
name: CDKD1;3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT;CDCKD;3" EXACT []
synonym: "T10F20.5" EXACT []
synonym: "CYCLIN-DEPENDENT KINASE D1;3" EXACT []
synonym: "T10F20_5" EXACT []
synonym: "AT1G18040" EXACT []
synonym: "CAK2AT" EXACT []
xref: TAIR:gene:2194044
[Term]
id: APO:B0000023
name: AT2G36010.3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G36010" EXACT []
xref: TAIR:gene:1006228006
[Term]
id: APO:R0000163
name: SP_KW
def: "UniProt Knowledgebase keywords" []
is_a: APO:R0000000 ! reference
comment: http://www.expasy.org/cgi-bin/keywlist.pl
[Term]
id: APO:R0000129
name: Swiss-Prot
def: "UniProtKB/Swiss-Prot, a curated protein sequence database which provides a high level of annotation and a minimal level of redundancy" []
is_a: APO:R0000000 ! reference
comment: http://www.uniprot.org
[Term]
id: APO:P0000194
name: negative regulation of cyclin-dependent protein kinase activity
def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity." [GOC:go_curators]
is_a: APO:P0000198 ! negative regulation of progression through cell cycle
is_a: APO:P0000009 ! regulation of cyclin-dependent protein kinase activity
synonym: "negative regulation of CDK activity" EXACT []
synonym: "CDK inhibitor" RELATED []
synonym: "cyclin-dependent kinase inhibitor" RELATED []
xref: GO:0045736
[Term]
id: APO:P0000255
name: male meiosis chromosome separation
def: "The process by which paired chromosomes are physically detached from each other during male meiosis." [GOC:ai]
is_a: APO:P0000065 ! male meiosis chromosome segregation
is_a: APO:P0000254 ! meiotic chromosome separation
synonym: "chromosome separation during male meiosis" EXACT []
xref: GO:0051308
[Term]
id: APO:B0000070
name: AT3G11520.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F24K9.20" EXACT []
synonym: "AT3G11520" EXACT []
xref: TAIR:gene:2080716
[Term]
id: APO:B0000132
name: E2F1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000288 ! positive regulation of progression through meiotic cell cycle
synonym: "AT5G22220" EXACT []
synonym: "ATE2FB" EXACT []
synonym: "E2F TRANSCRIPTION FACTOR-1 E2F1" EXACT []
synonym: "E2FB TRANSCRIPTION FACTOR" EXACT []
synonym: "E2FB" EXACT []
xref: TAIR:gene:3356520
[Term]
id: APO:P0000031
name: mitotic prometaphase
def: "Progression through prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles." [GOC:mah, ISBN:0198547684]
relationship: part_of APO:P0000069 ! mitosis
xref: GO:0000236
xref: Reactome:68877
[Term]
id: APO:R0000039
name: GeneDB_Tbrucei
def: "GeneDB_Tbrucei" []
is_a: APO:R0000000 ! reference
comment: http://www.genedb.org/genedb/tryp/
[Term]
id: APO:P0000014
name: G2 phase of mitotic cell cycle
def: "Progression through G2 phase, one of two 'gap' phases in the mitotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of mitosis." [ISBN:0815316194]
is_a: APO:P0000263 ! G2 phase
relationship: part_of APO:P0000273 ! interphase of mitotic cell cycle
xref: GO:0000085
xref: Reactome:68911
[Term]
id: APO:R0000126
name: SO
def: "Sequence Ontology" []
is_a: APO:R0000000 ! reference
comment: http://song.sourceforge.net/
[Term]
id: APO:P0000111
name: meiotic telophase I
def: "Progression through telophase of meiosis I; analogous to mitotic telophase." [GOC:mah]
is_a: APO:P0000270 ! telophase
relationship: part_of APO:P0000104 ! meiosis I
xref: GO:0007134
[Term]
id: APO:P0000243
name: mitotic spindle assembly
def: "The formation of the spindle during a mitotic cell cycle." [GOC:ai]
is_a: APO:P0000058 ! mitotic spindle organization and biogenesis
synonym: "mitotic spindle biogenesis" EXACT []
synonym: "mitotic spindle formation" EXACT []
synonym: "spindle assembly during mitosis" EXACT []
synonym: "spindle biogenesis during mitosis" EXACT []
synonym: "spindle formation during mitosis" EXACT []
xref: GO:0051227
[Term]
id: APO:P0000273
name: interphase of mitotic cell cycle
def: "Progression through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [GOC:ai]
is_a: APO:P0000269 ! interphase
relationship: part_of APO:P0000037 ! mitotic cell cycle
xref: GO:0051329
[Term]
id: APO:P0000107
name: synaptonemal complex formation
def: "Formation of the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination." [ISBN:0198506732]
relationship: part_of APO:P0000106 ! synapsis
xref: GO:0007130
[Term]
id: APO:P0000141
name: horsetail nuclear movement
def: "Oscillatory movement of the nucleus during meiotic prophase I, led by an astral microtubule array emanating from the spindle pole body, which may facilitate synapsis necessary for efficient meiotic recombination; as observed in S. pombe." [PMID:16111942, PMID:9572142]
relationship: part_of APO:P0000103 ! meiosis
synonym: "HNM" EXACT []
synonym: "horsetail movement" EXACT []
xref: GO:0030989
[Term]
id: APO:P0000080
name: lamin depolymerization
relationship: part_of APO:P0000079 ! mitotic nuclear envelope disassembly
xref: GO:0007078
[Term]
id: APO:P0000072
name: negative regulation of transcription from RNA polymerase II promoter, mitotic
def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators]
is_a: APO:P0000218 ! regulation of transcription from RNA polymerase II promoter, mitotic
is_a: APO:P0000070 ! negative regulation of transcription, mitotic
synonym: "mitotic repression of transcription from Pol II promoter" EXACT []
synonym: "negative regulation of transcription from Pol II promoter, mitotic" EXACT []
xref: GO:0007070
[Term]
id: APO:U0000002
name: process
def: "Entities that unfold themselves in successive temporal phases." [PMID:15892874]
disjoint_from: APO:U0000001
is_a: APO:U0000000 ! cell-cycle entity
synonym: "perdurant" EXACT [PMID:15892874]
synonym: "ocurrent" BROAD [PMID:15892874]
[Term]
id: APO:P0000206
name: regulation of transcription, mitotic
def: "Any process that modulates the frequency, rate or extent of transcription during mitosis." [GOC:go_curators]
relationship: part_of APO:P0000069 ! mitosis
synonym: "mitotic regulation of transcription" EXACT []
xref: GO:0045896
[Term]
id: APO:B0000156
name: PIN1AT
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "PROLYL CIS/TRANS ISOMERASE" EXACT []
synonym: "AT2G18040" EXACT []
xref: TAIR:gene:4370577
[Term]
id: APO:R0000107
name: protein_id
def: "The protein identifier shared by DDBJ/EMBL-bank/GenBank nucleotide" []
is_a: APO:R0000000 ! reference
[Term]
id: APO:P0000131
name: male meiotic spindle assembly (sensu Viridiplantae)
def: "The formation of the spindle in male meiotic cells. As in, but not restricted to, green plants and algae (Viridiplantae, ncbi_taxonomy_id:33090)." [PMID:11973272]
is_a: APO:P0000242 ! meiotic spindle assembly
relationship: part_of APO:P0000117 ! male meiosis
xref: GO:0009971
[Term]
id: APO:B0000049
name: AT1G16330.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F3O9_13" EXACT []
synonym: "AT1G16330" EXACT []
synonym: "F3O9.13" EXACT []
xref: TAIR:gene:2032869
[Term]
id: APO:B0000076
name: CYCP2;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT3G21870" EXACT []
synonym: "MEK6.1" EXACT []
xref: TAIR:gene:2088742
[Term]
id: APO:P0000209
name: positive regulation of progression through mitotic cell cycle
def: "Any process that activates or increases the frequency, rate or extent of progression through the mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000199 ! positive regulation of progression through cell cycle
is_a: APO:P0000124 ! regulation of progression through mitotic cell cycle
synonym: "positive regulation of mitotic cell cycle" EXACT []
synonym: "positive regulation of mitotic cell cycle progression" EXACT []
xref: GO:0045931
[Term]
id: APO:P0000227
name: positive regulation of mitotic centrosome separation
def: "Any process that activates or increases the frequency, rate or extent of centrosome separation." [GOC:ai]
is_a: APO:P0000225 ! regulation of mitotic centrosome separation
is_a: APO:P0000230 ! positive regulation of centrosome cycle
xref: GO:0046604
[Term]
id: APO:R0000042
name: GO
def: "Gene Ontology Database" []
is_a: APO:R0000000 ! reference
comment: http://godatabase.org/cgi-bin/go.cgi?query=
[Term]
id: APO:P0000164
name: spindle checkpoint
def: "A cell cycle checkpoint that delays the metaphase/anaphase transition until all chromosomes are attached to the spindle." [PMID:15897186]
is_a: APO:P0000005 ! cell cycle checkpoint
synonym: "spindle assembly checkpoint" EXACT []
synonym: "SAC" BROAD []
xref: GO:0031577
[Term]
id: APO:B0000057
name: CYCB1;4
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "CYCLIN B1;4" EXACT []
synonym: "F18A8.13" EXACT []
synonym: "AT2G26760" EXACT []
synonym: "F18A8_13" EXACT []
xref: TAIR:gene:2043817
[Term]
id: APO:P0000049
name: resolution of meiotic joint molecules as recombinants
def: "The cleavage and rejoining of Holliday junctions to produce two intact molecules in which genetic material has been exchanged." [GOC:elh, PMID:11733053]
is_a: APO:P0000254 ! meiotic chromosome separation
relationship: part_of APO:P0000191 ! homologous chromosome segregation
relationship: part_of APO:P0000108 ! meiotic recombination
synonym: "homologous chromosome separation at meiosis I" EXACT []
synonym: "crossover formation" NARROW []
synonym: "formation of chiasmata" NARROW []
synonym: "meiotic homologous chromosome separation" RELATED []
xref: GO:0000712
[Term]
id: APO:R0000054
name: HGNC
def: "HUGO Gene Nomenclature Committee" []
is_a: APO:R0000000 ! reference
comment: http://www.gene.ucl.ac.uk/nomenclature/
[Term]
id: APO:R0000144
name: TIGR_TGI
def: "The Institute for Genomic Research, TIGR Gene Index" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/
[Term]
id: APO:P0000244
name: mitotic spindle disassembly
def: "The controlled breakdown of the spindle during a mitotic cell cycle." [GOC:ai]
is_a: APO:P0000058 ! mitotic spindle organization and biogenesis
synonym: "mitotic spindle breakdown" EXACT []
synonym: "mitotic spindle degradation" EXACT []
synonym: "spindle breakdown during mitosis" EXACT []
synonym: "spindle degradation during mitosis" EXACT []
synonym: "spindle disassembly during mitosis" EXACT []
xref: GO:0051228
[Term]
id: APO:R0000063
name: IUPHAR
def: "The IUPHAR Compendium of Receptor Characterization and Classification" []
is_a: APO:R0000000 ! reference
[Term]
id: APO:R0000051
name: H-invDB_cDNA
def: "H-invitational Database" []
is_a: APO:R0000000 ! reference
comment: http://www.h-invitational.jp/
[Term]
id: APO:P0000291
name: attachment of spindle microtubules to kinetochore during meiosis II
def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs." [GOC:ai, GOC:clt]
is_a: APO:P0000260 ! attachment of spindle microtubules to kinetochore during meiotic chromosome segregation
relationship: part_of APO:P0000192 ! meiotic sister chromatid segregation
xref: GO:0051456
[Term]
id: APO:P0000188
name: negative regulation of meiotic recombination
def: "Any process that stops, prevents or reduces the frequency, rate or extent of recombination during meiosis." [GOC:ai]
is_a: APO:P0000200 ! negative regulation of meiosis
relationship: part_of APO:P0000108 ! meiotic recombination
synonym: "suppression of meiotic recombination" EXACT []
xref: GO:0045128
[Term]
id: APO:P0000054
name: meiotic gene conversion
def: "The transfer of genetic information from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele." [ISBN:0815316194]
relationship: part_of APO:P0000104 ! meiosis I
synonym: "gene conversion without reciprocal crossover" EXACT []
xref: GO:0006311
[Term]
id: APO:P0000264
name: S phase
def: "Progression through S phase, the part of the cell cycle during which DNA synthesis takes place." [GOC:ai]
relationship: part_of APO:P0000269 ! interphase
xref: GO:0051320
[Term]
id: APO:B0000150
name: TAM
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000117 ! male meiosis
synonym: "DYP" EXACT []
synonym: "TARDY ASYNCHRONOUS MEIOSIS" EXACT []
xref: TAIR:gene:3714773
[Term]
id: APO:R0000083
name: NCBI
def: "National Center for Biotechnology Information, Bethesda" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/
[Term]
id: APO:B0000080
name: KRP6
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "MVI11.5" EXACT []
synonym: "AT3G19150" EXACT []
synonym: "KIP-RELATED PROTEIN 6" EXACT []
xref: TAIR:gene:2094117
[Term]
id: APO:R0000033
name: FLYBASE
def: "FlyBase" []
is_a: APO:R0000000 ! reference
comment: http://flybase.bio.indiana.edu/
[Term]
id: APO:R0000104
name: PRINTS
def: "PRINTS compendium of protein fingerprints" []
is_a: APO:R0000000 ! reference
comment: http://umber.sbs.man.ac.uk/dbbrowser/PRINTS/
[Term]
id: APO:P0000146
name: regulation of septation initiation signaling
def: "Any process that modulates the frequency, rate or extent of septation initiation signaling." [GOC:mah]
relationship: part_of APO:P0000145 ! septation initiation signaling
synonym: "regulation of septation initiation network" EXACT []
synonym: "regulation of septation initiation signalling" EXACT []
xref: GO:0031029
[Term]
id: APO:B0000075
name: RNR2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "MDB19.1" EXACT []
synonym: "AT3G23580" EXACT []
synonym: "RNR2A" EXACT []
xref: TAIR:gene:2088039
[Term]
id: APO:B0000120
name: CYCA1;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "Cyclin A1;1" EXACT []
synonym: "T7O23_18" EXACT []
synonym: "AT1G44110" EXACT []
synonym: "T7O23.18" EXACT []
xref: TAIR:gene:2205870
[Term]
id: APO:P0000026
name: G2/M-specific transcription in mitotic cell cycle
def: "Any process that regulates transcription such that the target genes are transcribed during the G2/M phase of the mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000015 ! G2/M transition of mitotic cell cycle
xref: GO:0000117
xref: Reactome:69274
[Term]
id: APO:P0000009
name: regulation of cyclin-dependent protein kinase activity
def: "Any process that modulates the frequency, rate or extent of CDK activity." [GOC:go_curators]
is_a: APO:P0000004 ! regulation of progression through cell cycle
synonym: "regulation of CDK activity" EXACT []
xref: GO:0000079
[Term]
id: APO:R0000134
name: TGD_LOCUS
def: "Tetrahymena Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.ciliate.org/
[Term]
id: APO:P0000152
name: cytokinesis checkpoint
def: "A cell cycle checkpoint that ensures the correct temporal ordering of nuclear division and cytokinesis; arrests the cell cycle in G2 upon perturbation of cytokinetic structures. In Schizosaccharomyces, the checkpoint monitors formation and integrity of medial actomyosin ring and septum." [GOC:mah, PMID:15647375]
is_a: APO:P0000005 ! cell cycle checkpoint
synonym: "contractile ring checkpoint" EXACT []
xref: GO:0031565
[Term]
id: APO:R0000008
name: BRENDA
def: "BRENDA, The Comprehensive Enzyme Information System" []
is_a: APO:R0000000 ! reference
comment: http://www.brenda.uni-koeln.de/
[Term]
id: APO:R0000125
name: SMD
def: "Stanford Microarray Database" []
is_a: APO:R0000000 ! reference
comment: http://genome-www.stanford.edu/microarray
[Term]
id: APO:P0000140
name: mitotic spindle organization and biogenesis in nucleus
def: "The formation and maintenance of the spindle in the nucleus, as seen in Fungi during a mitotic cell cycle." [GOC:mah]
is_a: APO:P0000058 ! mitotic spindle organization and biogenesis
synonym: "mitotic spindle organisation and biogenesis in nucleus" EXACT []
synonym: "spindle organization and biogenesis in nucleus during mitosis" EXACT []
synonym: "mitotic spindle assembly (sensu Fungi)" NARROW []
synonym: "mitotic spindle assembly (sensu Saccharomyces)" NARROW []
xref: GO:0030472
xref: GO:0000071
[Term]
id: APO:B0000131
name: SYN2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000069 ! mitosis
synonym: "AT5G40840" EXACT []
xref: TAIR:gene:3356081
[Term]
id: APO:B0000126
name: RBR1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000011 ! G1/S transition of mitotic cell cycle
synonym: "RB" EXACT []
synonym: "AT3G12280" EXACT []
synonym: "RETINOBLASTOMA-RELATED 1" EXACT []
synonym: "RETINOBLASTOMA PROTEIN" EXACT []
synonym: "RBL1" EXACT []
xref: TAIR:gene:3354602
[Term]
id: APO:P0000063
name: female meiosis I spindle assembly (sensu Metazoa)
def: "The formation of the spindle during meiosis I of a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
is_a: APO:P0000062 ! female meiotic spindle assembly (sensu Metazoa)
relationship: part_of APO:P0000121 ! female meiosis I
xref: GO:0007057
[Term]
id: APO:P0000029
name: meiotic spindle organization and biogenesis
def: "The formation and maintenance of the microtubule spindle during a meiotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000265 ! meiotic cell cycle
synonym: "meiotic spindle organisation and biogenesis" EXACT []
synonym: "spindle organization and biogenesis during meiosis" EXACT []
xref: GO:0000212
[Term]
id: APO:P0000197
name: positive regulation of S phase of mitotic cell cycle
def: "Any process that activates or increases the frequency, rate or extent of S phase of mitotic cell cycle activity." [GOC:go_curators]
is_a: APO:P0000209 ! positive regulation of progression through mitotic cell cycle
is_a: APO:P0000089 ! regulation of S phase of mitotic cell cycle
xref: GO:0045750
[Term]
id: APO:P0000074
name: activation of transcription on exit from mitosis
relationship: part_of APO:P0000016 ! M phase of mitotic cell cycle
xref: GO:0007072
[Term]
id: APO:U0000009
name: small molecule
def: "A small structural unit of matter consisting of one or more atoms." [APO:ea]
is_a: APO:U0000001 ! continuant
[Term]
id: APO:R0000089
name: PAMGO
def: "Plant-Associated Microbe Gene Ontology Interest Group" []
is_a: APO:R0000000 ! reference
comment: http://pamgo.vbi.vt.edu/
[Term]
id: APO:P0000043
name: meiotic DNA double-strand break processing
def: "During meiosis, the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang." [GOC:elh, PMID:9334324]
relationship: part_of APO:P0000054 ! meiotic gene conversion
relationship: part_of APO:P0000108 ! meiotic recombination
xref: GO:0000706
[Term]
id: APO:B0000086
name: AT4G19560.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT4G19560" EXACT []
synonym: "F24J7.120" EXACT []
synonym: "F24J7_120" EXACT []
xref: TAIR:gene:2122939
[Term]
id: APO:R0000015
name: ChEBI
def: "Chemical Entities of Biological Interest" []
is_a: APO:R0000000 ! reference
comment: http://www.ebi.ac.uk/chebi/
[Term]
id: APO:B0000094
name: AT4G02570.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "AT4G02570" EXACT []
synonym: "T10P11_26" EXACT []
synonym: "T10P11.26" EXACT []
xref: TAIR:gene:2132376
[Term]
id: APO:R0000099
name: PMID
def: "PubMed" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/PubMed/
[Term]
id: APO:R0000143
name: TIGR_Tba1
def: "The Institute for Genomic Research, Trypanosoma brucei database" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/tdb/e2k1/tba1/
[Term]
id: APO:P0000181
name: early meiotic recombination nodule assembly
def: "The assembly of small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene." [GOC:jl, PMID:9334324]
is_a: APO:P0000122 ! meiotic recombination nodule assembly
xref: GO:0042139
[Term]
id: APO:R0000164
name: VEGA
def: "The Vertebrate Genome Annotation database" []
is_a: APO:R0000000 ! reference
comment: http://vega.sanger.ac.uk/index.html
[Term]
id: APO:B0000042
name: AT1G16590.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000093 ! mitotic spindle checkpoint
synonym: "AT1G16590" EXACT []
synonym: "F19K19_10" EXACT []
synonym: "F19K19.10" EXACT []
xref: TAIR:gene:2017957
[Term]
id: APO:P0000050
name: meiotic heteroduplex formation
def: "During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules." [GOC:elh, PMID:9334324]
relationship: part_of APO:P0000054 ! meiotic gene conversion
xref: GO:0000713
[Term]
id: APO:P0000228
name: regulation of centrosome cycle
def: "Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation." [GOC:ai]
relationship: part_of APO:P0000096 ! centrosome cycle
xref: GO:0046605
[Term]
id: APO:B0000043
name: AT1G43140.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "F1I21_19" EXACT []
synonym: "F1I21.19" EXACT []
synonym: "AT1G43140" EXACT []
xref: TAIR:gene:2018644
[Term]
id: APO:R0000116
name: REBASE
def: "REBASE, The Restriction Enzyme Database" []
is_a: APO:R0000000 ! reference
comment: http://rebase.neb.com/rebase/rebase.html
[Term]
id: APO:P0000254
name: meiotic chromosome separation
def: "The process by which chromosomes are physically detached from each other during meiosis." [GOC:ai]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
synonym: "chromosome separation during meiosis" EXACT []
xref: GO:0051307
[Term]
id: APO:P0000280
name: interphase microtubule nucleation by interphase microtubule organizing center
def: "The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation." [GOC:ai]
relationship: part_of APO:P0000269 ! interphase
synonym: "IMTOC-mediated microtubule nucleation during interphase" EXACT []
synonym: "interphase microtubule nucleation by interphase microtubule organising centre" EXACT []
synonym: "interphase microtubule organizing center-mediated microtubule nucleation during interphase" EXACT []
synonym: "microtubule nucleation during interphase by IMTOC" EXACT []
synonym: "microtubule nucleation during interphase by interphase microtubule organizing center" EXACT []
xref: GO:0051415
[Term]
id: APO:P0000205
name: positive regulation of mitotic metaphase/anaphase transition
def: "Any process that activates or increases the frequency, rate or extent of the mitotic metaphase to anaphase transition." [GOC:go_curators]
is_a: APO:P0000139 ! regulation of mitotic metaphase/anaphase transition
is_a: APO:P0000203 ! positive regulation of mitosis
xref: GO:0045842
[Term]
id: APO:B0000058
name: RPN1A
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F23N11.10" EXACT []
synonym: "AtRPN1a" EXACT []
synonym: "F23N11_10" EXACT []
synonym: "AT2G20580" EXACT []
xref: TAIR:gene:2046015
[Term]
id: APO:P0000130
name: cell plate formation (sensu Magnoliophyta)
def: "The processes involved in the formation of the cell plate at the equator of the spindle in the dividing cells during early telophase. As in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398)." [GOC:tb, ISBN:0879015322]
relationship: part_of APO:P0000069 ! mitosis
xref: GO:0009920
[Term]
id: APO:P0000073
name: negative regulation of transcription from RNA polymerase III promoter, mitotic
def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators]
is_a: APO:P0000220 ! regulation of transcription from RNA polymerase III promoter, mitotic
is_a: APO:P0000070 ! negative regulation of transcription, mitotic
synonym: "mitotic repression of transcription from Pol III promoter" EXACT []
synonym: "negative regulation of transcription from Pol III promoter, mitotic" EXACT []
xref: GO:0007071
[Term]
id: APO:P0000048
name: meiotic DNA repair synthesis
def: "During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template." [GOC:elh, PMID:9334324]
relationship: part_of APO:P0000054 ! meiotic gene conversion
relationship: part_of APO:P0000108 ! meiotic recombination
xref: GO:0000711
[Term]
id: APO:B0000117
name: E2FC
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G47870" EXACT []
synonym: "T2E6.2" EXACT []
synonym: "T2E6_2" EXACT []
xref: TAIR:gene:2202389
[Term]
id: APO:R0000001
name: AgBase
def: "AgBase resource for functional analysis of agricultural plant and animal gene products" []
is_a: APO:R0000000 ! reference
comment: http://www.agbase.msstate.edu/
[Term]
id: APO:P0000104
name: meiosis I
def: "Progression through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." [PMID:9334324]
relationship: part_of APO:P0000103 ! meiosis
xref: GO:0007127
[Term]
id: APO:P0000212
name: negative regulation of progression through preblastoderm mitotic cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the preblastoderm mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000210 ! negative regulation of progression through embryonic mitotic cell cycle
is_a: APO:P0000125 ! regulation of progression through preblastoderm mitotic cell cycle
synonym: "negative regulation of preblastoderm mitotic cell cycle progression" EXACT []
xref: GO:0046001
[Term]
id: APO:R0000013
name: CGEN
def: "Compugen Gene Ontology Gene Association Data" []
is_a: APO:R0000000 ! reference
comment: http://www.cgen.com/
[Term]
id: APO:B0000019
name: APC11
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000124 ! regulation of progression through mitotic cell cycle
synonym: "AT3G05870" EXACT []
xref: TAIR:gene:1005964064
[Term]
id: APO:P0000149
name: sister chromatid biorientation
def: "The process by which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles." [PMID:15309047]
relationship: part_of APO:P0000082 ! mitotic metaphase plate congression
synonym: "chromosome biorientation" EXACT []
synonym: "sister kinetochore biorientation" EXACT []
xref: GO:0031134
[Term]
id: APO:R0000159
name: ZFIN
def: "The Zebrafish Information Network" []
is_a: APO:R0000000 ! reference
comment: http://zfin.org/
[Term]
id: APO:R0000043
name: GO_REF
def: "Gene Ontology Database references" []
is_a: APO:R0000000 ! reference
[Term]
id: APO:R0000103
name: PPI
def: "The Pseudomonas syringae community annotation project" []
is_a: APO:R0000000 ! reference
comment: http://genome.pseudomonas-syringae.org/
[Term]
id: APO:R0000027
name: ECOGENE
def: "The EcoGene Database of Escherichia coli Sequence and Function" []
is_a: APO:R0000000 ! reference
comment: http://www.ecogene.org/
[Term]
id: APO:R0000152
name: UniParc
def: "UniProt Archive; a non-redundant archive of protein sequences extracted from Swiss-Prot, TrEMBL, PIR-PSD, EMBL, Ensembl, IPI, PDB, RefSeq, FlyBase, WormBase, European Patent Office, United States Patent and Trademark Office, and Japanese Patent Office" []
is_a: APO:R0000000 ! reference
comment: http://www.ebi.ac.uk/uniparc/
[Term]
id: APO:P0000261
name: attachment of spindle microtubules to meiotic chromosome
def: "The process by which spindle microtubules become physically associated with a chromosome during meiosis." [GOC:ai]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
xref: GO:0051317
[Term]
id: APO:R0000021
name: DDB
def: "DictyBase" []
is_a: APO:R0000000 ! reference
comment: http://dictybase.org
[Term]
id: APO:P0000123
name: female meiosis II
def: "The second meiotic division in the female germline." [GOC:mah]
relationship: part_of APO:P0000120 ! female meiosis
xref: GO:0007147
[Term]
id: APO:P0000030
name: M/G1 transition of mitotic cell cycle
def: "Progression from M phase to G1 phase of the mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000273 ! interphase of mitotic cell cycle
xref: GO:0000216
xref: Reactome:68874
[Term]
id: APO:B0000001
name: AT1G47210.2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G47210" EXACT []
xref: TAIR:gene:1005027859
[Term]
id: APO:B0000031
name: AT4G02570.3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "AT4G02570" EXACT []
xref: TAIR:gene:1009022198
[Term]
id: APO:P0000171
name: G2/M-specific negative regulation of cyclin-dependent protein kinase activity
def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah]
is_a: APO:P0000170 ! G2/M-specific regulation of cyclin-dependent protein kinase activity
is_a: APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
xref: GO:0031661
[Term]
id: APO:B0000078
name: TSO2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT3G27060" EXACT []
synonym: "MOJ10.15" EXACT []
xref: TAIR:gene:2092029
[Term]
id: APO:P0000013
name: S phase of mitotic cell cycle
def: "Progression through S phase, the part of the mitotic cell cycle during which DNA synthesis takes place." [ISBN:0815316194]
is_a: APO:P0000264 ! S phase
relationship: part_of APO:P0000273 ! interphase of mitotic cell cycle
xref: GO:0000084
[Term]
id: APO:P0000290
name: attachment of spindle microtubules to kinetochore during meiosis I
def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs." [GOC:ai, GOC:clt]
is_a: APO:P0000260 ! attachment of spindle microtubules to kinetochore during meiotic chromosome segregation
relationship: part_of APO:P0000191 ! homologous chromosome segregation
synonym: "monopolar attachment" EXACT []
synonym: "sister kinetochore monoorientation" EXACT []
comment: Note that the synonym 'monopolar attachment' refers to the normal attachment of sister chromosomes to the spindle in meiosis I, and not to the aberrant attachment of sister kinetochores to a single pole in mitosis.
xref: GO:0051455
[Term]
id: APO:B0000130
name: ATK1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000131 ! male meiotic spindle assembly (sensu Viridiplantae)
synonym: "AT4G21270" EXACT []
synonym: "KATA" EXACT []
synonym: "KATAP" EXACT []
synonym: "ARABIDOPSIS THALIANA KINESIN 1" EXACT []
synonym: "KINESIN-LIKE PROTEIN A" EXACT []
xref: TAIR:gene:3355332
[Term]
id: APO:R0000149
name: UM-BBD
def: "The University of Minnesota Biocatalysis/Biodegradation Database" []
is_a: APO:R0000000 ! reference
comment: http://umbbd.ahc.umn.edu/index.html
[Term]
id: APO:P0000211
name: positive regulation of mitotic cell cycle, embryonic
def: "Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000209 ! positive regulation of progression through mitotic cell cycle
is_a: APO:P0000129 ! regulation of progression through embryonic mitotic cell cycle
synonym: "positive regulation of embryonic mitotic cell cycle progression" EXACT []
xref: GO:0045977
[Term]
id: APO:B0000112
name: CYCP4;3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "T2I1_160" EXACT []
synonym: "AT5G07450" EXACT []
synonym: "T2I1.160" EXACT []
xref: TAIR:gene:2183393
[Term]
id: APO:P0000066
name: mitotic sister chromatid cohesion
def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during mitosis. This cohesion cycle is critical for high fidelity chromosome transmission." [GOC:ai, GOC:rn, PMID:10827941, PMID:11389843]
relationship: part_of APO:P0000002 ! mitotic sister chromatid segregation
synonym: "mitotic sister-chromatid adhesion release" RELATED []
xref: GO:0007064
[Term]
id: APO:R0000014
name: CGSC
def: "CGSC: E.coli Genetic Stock Center" []
is_a: APO:R0000000 ! reference
comment: http://cgsc.biology.yale.edu/
[Term]
id: APO:R0000142
name: TIGR_REF
def: "The Institute for Genomic Research" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/tdb/GO_REF/GO_REF.shtml
[Term]
id: APO:R0000078
name: MIPS_funcat
def: "MIPS Functional Catalogue" []
is_a: APO:R0000000 ! reference
comment: http://mips.gsf.de/proj/funcatDB/
[Term]
id: APO:P0000032
name: leptotene
def: "Progression through the first stage of prophase I in meiosis, in which chromosomes first become visible." [ISBN:0198547684]
relationship: part_of APO:P0000105 ! meiotic prophase I
xref: GO:0000237
[Term]
id: APO:P0000223
name: negative regulation of centriole replication
def: "Any process that stops, prevents or reduces the frequency, rate or extent of centriole replication." [GOC:ai]
is_a: APO:P0000222 ! regulation of centriole replication
is_a: APO:P0000229 ! negative regulation of centrosome cycle
xref: GO:0046600
[Term]
id: APO:P0000276
name: S phase of meiotic cell cycle
def: "Progression through S phase, the part of the meiotic cell cycle during which DNA synthesis takes place." [GOC:ai]
is_a: APO:P0000264 ! S phase
relationship: part_of APO:P0000272 ! interphase of meiotic cell cycle
xref: GO:0051332
[Term]
id: APO:B0000060
name: AT2G41830.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G41830" EXACT []
synonym: "T11A7.7" EXACT []
synonym: "T11A7_7" EXACT []
xref: TAIR:gene:2054415
[Term]
id: APO:B0000055
name: AT2G36010.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G36010" EXACT []
synonym: "F11F19.8" EXACT []
synonym: "F11F19_8" EXACT []
xref: TAIR:gene:2039219
[Term]
id: APO:P0000071
name: negative regulation of transcription from RNA polymerase I promoter, mitotic
def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators]
is_a: APO:P0000216 ! regulation of transcription from RNA polymerase I promoter, mitotic
is_a: APO:P0000070 ! negative regulation of transcription, mitotic
synonym: "mitotic repression of transcription from Pol I promoter" EXACT []
synonym: "negative regulation of transcription from Pol I promoter, mitotic" EXACT []
xref: GO:0007069
[Term]
id: APO:U0000001
name: continuant
def: "Entities which endure, or continue to exist, through time while undergoing different sort of changes, including changes of place." [PMID:15892874]
disjoint_from: APO:U0000002
is_a: APO:U0000000 ! cell-cycle entity
synonym: "endurant" EXACT [PMID:15892874]
synonym: "thing" BROAD [PMID:15892874]
[Term]
id: APO:P0000200
name: negative regulation of meiosis
def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiosis." [GOC:go_curators]
is_a: APO:P0000178 ! regulation of meiosis
xref: GO:0045835
[Term]
id: APO:P0000252
name: centrosome separation
def: "The process by which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle." [GOC:ai]
relationship: part_of APO:P0000096 ! centrosome cycle
xref: GO:0051299
[Term]
id: APO:R0000155
name: WB
def: "WormBase, database of nematode biology" []
is_a: APO:R0000000 ! reference
comment: http://www.wormbase.org/
[Term]
id: APO:R0000097
name: PINC
def: "Proteome Inc.; represents GO annotations created in 2001 for NCBI and extracted into GOA from EntrezGene" []
is_a: APO:R0000000 ! reference
comment: http://www.proteome.com/
[Term]
id: APO:P0000124
name: regulation of progression through mitotic cell cycle
def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000004 ! regulation of progression through cell cycle
relationship: part_of APO:P0000037 ! mitotic cell cycle
synonym: "control of mitotic cell cycle progression" EXACT []
synonym: "mitotic cell cycle control" EXACT []
synonym: "mitotic cell cycle modulation" EXACT []
synonym: "mitotic cell cycle regulation" EXACT []
synonym: "modulation of mitotic cell cycle progression" EXACT []
synonym: "regulation of mitotic cell cycle" EXACT []
synonym: "regulation of mitotic cell cycle progression" EXACT []
synonym: "mitotic cell cycle regulator" RELATED []
xref: GO:0007346
[Term]
id: APO:P0000119
name: male meiosis II
def: "The second meiotic division in the male germline." [GOC:mah]
relationship: part_of APO:P0000117 ! male meiosis
xref: GO:0007142
[Term]
id: APO:R0000009
name: CBS
def: "Center for Biological Sequence Analysis" []
is_a: APO:R0000000 ! reference
comment: http://www.cbs.dtu.dk/
[Term]
id: APO:P0000298
name: meiotic sister chromatid cohesion, centromeric
def: "The joining of the centromeres of sister chromatids that occurs during meiosis." [PMID:14730319, PMID:16325576]
relationship: part_of APO:P0000240 ! meiotic sister chromatid cohesion
synonym: "meiotic sister chromatid cohesion at centromere" EXACT []
synonym: "sister chromatid cohesion at centromere at meiosis I" EXACT []
xref: GO:0051754
[Term]
id: APO:B0000067
name: AT2G26430.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G26430" EXACT []
synonym: "T9J22_10" EXACT []
synonym: "T9J22.10" EXACT []
xref: TAIR:gene:2066184
[Term]
id: APO:P0000305
name: lateral element assembly
def: "The process by which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements." [PMID:11463847]
relationship: part_of APO:P0000107 ! synaptonemal complex formation
xref: GO:0051878
[Term]
id: APO:P0000003
name: M phase specific microtubule process
def: "A microtubule-based process that occurs only during M phase of the cell cycle." [GOC:mah]
relationship: part_of APO:P0000038 ! M phase
synonym: "M-phase specific microtubule process" EXACT []
xref: GO:0000072
[Term]
id: APO:R0000112
name: PubChem_BioAssay
def: "NCBI PubChem database of bioassay records" []
is_a: APO:R0000000 ! reference
comment: http://pubchem.ncbi.nlm.nih.gov/
[Term]
id: APO:P0000281
name: negative regulation of ubiquitin ligase activity during mitotic cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai]
is_a: APO:P0000283 ! regulation of ubiquitin ligase activity during mitotic cell cycle
synonym: "anaphase promoting complex inhibition during mitotic cell cycle" NARROW []
synonym: "anaphase-promoting complex inhibition during mitotic cell cycle" NARROW []
synonym: "APC inhibition during mitotic cell cycle" NARROW []
synonym: "mitotic anaphase promoting complex inhibition" NARROW []
synonym: "mitotic anaphase promoting complex inhibitor" NARROW []
synonym: "mitotic anaphase-promoting complex inhibition" NARROW []
synonym: "mitotic anaphase-promoting complex inhibitor" NARROW []
synonym: "mitotic APC inhibition" NARROW []
synonym: "mitotic APC inhibitor" NARROW []
synonym: "mitotic SCF complex inhibitor" NARROW []
synonym: "mitotic ubiquitin ligase inhibitor" NARROW []
xref: GO:0051436
[Term]
id: APO:R0000012
name: CGD_REF
def: "Candida Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.candidagenome.org/
[Term]
id: APO:R0000052
name: H-invDB_locus
def: "H-invitational Database" []
is_a: APO:R0000000 ! reference
comment: http://www.h-invitational.jp/
[Term]
id: APO:P0000193
name: mitotic cell cycle, embryonic
def: "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo." [GOC:go_curators]
is_a: APO:P0000037 ! mitotic cell cycle
xref: GO:0045448
[Term]
id: APO:B0000065
name: AT2G29680.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G29680" EXACT []
synonym: "T27A16.22" EXACT []
synonym: "T27A16_22" EXACT []
xref: TAIR:gene:2060658
[Term]
id: APO:P0000113
name: meiotic prophase II
def: "Progression through prophase of meiosis II; analogous to mitotic prophase." [GOC:mah]
is_a: APO:P0000268 ! prophase
relationship: part_of APO:P0000112 ! meiosis II
xref: GO:0007136
[Term]
id: APO:P0000052
name: cell cycle arrest in response to pheromone
def: "The processes that lead to a halt in cell cycle progression (cessation of cell cycle transitions) as a result of a pheromone stimulus." [GOC:clt]
is_a: APO:P0000057 ! cell cycle arrest
synonym: "cell cycle arrest (sensu Saccharomyces)" RELATED []
xref: GO:0000751
xref: GO:0030571
[Term]
id: APO:P0000173
name: regulation of contractile ring contraction during cytokinesis
def: "Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring during cytokinesis." [GOC:mah]
is_a: APO:P0000004 ! regulation of progression through cell cycle
xref: GO:0031991
[Term]
id: APO:R0000161
name: MA
def: "Adult Mouse Anatomical Dictionary; part of Gene Expression Database" []
is_a: APO:R0000000 ! reference
comment: http://www.informatics.jax.org/
[Term]
id: APO:R0000000
name: reference
is_a: APO:U0000001 ! continuant
[Term]
id: APO:P0000097
name: centriole replication
def: "Formation of a daughter centriole perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type." [GOC:kva, ISBN:0815316194]
relationship: part_of APO:P0000251 ! centrosome duplication
synonym: "centriole duplication" EXACT []
xref: GO:0007099
[Term]
id: APO:R0000071
name: MEDLINE
def: "The Medline literature database" []
is_a: APO:R0000000 ! reference
[Term]
id: APO:B0000002
name: AT2G29680.2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G29680" EXACT []
xref: TAIR:gene:1005714820
[Term]
id: APO:P0000226
name: negative regulation of mitotic centrosome separation
def: "Any process that stops, prevents or reduces the frequency, rate or extent of centrosome separation." [GOC:ai]
is_a: APO:P0000225 ! regulation of mitotic centrosome separation
is_a: APO:P0000229 ! negative regulation of centrosome cycle
xref: GO:0046603
[Term]
id: APO:P0000253
name: mitotic sister chromatid separation
def: "The process by which sister chromatids are physically detached from each other during mitosis." [GOC:ai]
relationship: part_of APO:P0000002 ! mitotic sister chromatid segregation
synonym: "sister chromatid separation during mitosis" EXACT []
synonym: "chromosome separation during mitosis" RELATED []
synonym: "mitotic chromosome separation" RELATED []
xref: GO:0051306
[Term]
id: APO:R0000120
name: Sanger
def: "The Wellcome Trust Sanger Institute" []
is_a: APO:R0000000 ! reference
comment: http://www.sanger.ac.uk/
[Term]
id: APO:P0000102
name: endomitotic cell cycle
def: "The replication and division of chromosomes which is not followed by nuclear division, resulting in an increased number of chromosomes in the cell." [http:www.onelook.com]
is_a: APO:P0000056 ! cell cycle
synonym: "endomitosis" EXACT []
xref: GO:0007113
[Term]
id: APO:P0000162
name: G1/S transition checkpoint
def: "Any cell cycle checkpoint that blocks entry into S phase." [GOC:mah]
is_a: APO:P0000005 ! cell cycle checkpoint
xref: GO:0031575
[Term]
id: APO:R0000061
name: ISBN
def: "International Standard Book Number" []
is_a: APO:R0000000 ! reference
comment: http://isbntools.com/
[Term]
id: APO:P0000120
name: female meiosis
def: "Meiosis in the female germline." [GOC:ems]
is_a: APO:P0000103 ! meiosis
comment: Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaprodites such as those of C. elegans. See also the biological process term 'meiosis ; GO:0007126'.
xref: GO:0007143
[Term]
id: APO:B0000124
name: ASY1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000106 ! synapsis
synonym: "ASYNAPTIC 1" EXACT []
synonym: "AT1G67370" EXACT []
xref: TAIR:gene:3353693
[Term]
id: APO:R0000003
name: AGRICOLA_bib
def: "AGRICultural OnLine Access" []
is_a: APO:R0000000 ! reference
comment: http://agricola.nal.usda.gov/
[Term]
id: APO:P0000019
name: mitotic anaphase
def: "Progression through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other." [ISBN:0815316194]
is_a: APO:P0000266 ! anaphase
relationship: part_of APO:P0000069 ! mitosis
xref: GO:0000090
xref: Reactome:68882
[Term]
id: APO:B0000024
name: AT2G36010.2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G36010" EXACT []
xref: TAIR:gene:1006228007
[Term]
id: APO:R0000031
name: ENZYME
def: "The Swiss Institute of Bioinformatics database of Enzymes" []
is_a: APO:R0000000 ! reference
comment: http://www.expasy.ch/
[Term]
id: APO:B0000087
name: AT4G19600.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F24J7.161" EXACT []
synonym: "AT4G19600" EXACT []
synonym: "F24J7_161" EXACT []
xref: TAIR:gene:2122974
[Term]
id: APO:P0000155
name: G1/S transition size control checkpoint
def: "A cell cycle checkpoint that blocks cell cycle progression from G1 to S phase until cells have reached a critical size." [GOC:mah]
is_a: APO:P0000154 ! cell size control checkpoint
is_a: APO:P0000162 ! G1/S transition checkpoint
xref: GO:0031568
[Term]
id: APO:R0000093
name: PfamB
def: "Pfam-B supplement to Pfam" []
is_a: APO:R0000000 ! reference
comment: http://www.sanger.ac.uk/Software/Pfam/
[Term]
id: APO:P0000137
name: modification by virus of host cell cycle regulation
def: "Viral processes that modulate the rate of the host cell cycle to facilitate virus replication." [ISBN:0781718325]
is_a: APO:P0000004 ! regulation of progression through cell cycle
synonym: "viral perturbation of cell cycle regulation" EXACT []
xref: GO:0019055
[Term]
id: APO:B0000137
name: CYCB1;2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "CYCLIN B1;2" EXACT []
synonym: "AT5G06150" EXACT []
synonym: "MBL20.2" EXACT []
synonym: "MBL20_2" EXACT []
xref: TAIR:gene:3440834
[Term]
id: APO:P0000055
name: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle." [GOC:go_curators]
is_a: APO:P0000158 ! G1 DNA damage checkpoint
xref: GO:0006977
[Term]
id: APO:R0000040
name: GenProtEC
def: "GenProtEC E. coli genome and proteome database" []
is_a: APO:R0000000 ! reference
comment: http://genprotec.mbl.edu/
[Term]
id: APO:B0000012
name: ICK4
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "KRP6" EXACT []
synonym: "AT3G19150" EXACT []
xref: TAIR:gene:1005867754
[Term]
id: APO:B0000142
name: KRP4
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000198 ! negative regulation of progression through cell cycle
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "ICK7" EXACT []
synonym: "CYCLIN-DEPENDENT KINASE INHIBITOR 2" EXACT []
synonym: "KIP-RELATED PROTEIN 4" EXACT []
synonym: "ACK2" EXACT []
synonym: "AT2G32710" EXACT []
xref: TAIR:gene:3685844
[Term]
id: APO:P0000143
name: regulation of centriole-centriole cohesion
def: "Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker." [PMID:11076968]
relationship: part_of APO:P0000096 ! centrosome cycle
xref: GO:0030997
[Term]
id: APO:B0000039
name: AT1G07270.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F10K1.2" EXACT []
synonym: "AT1G07270" EXACT []
synonym: "F10K1_2" EXACT []
xref: TAIR:gene:2007331
[Term]
id: APO:R0000064
name: KEGG
def: "Kyoto Encyclopedia of Genes and Genomes" []
is_a: APO:R0000000 ! reference
comment: http://www.genome.ad.jp/kegg/
[Term]
id: APO:R0000136
name: TIGR
def: "The Institute for Genomic Research" []
is_a: APO:R0000000 ! reference
comment: http://www.tigr.org/
[Term]
id: APO:P0000079
name: mitotic nuclear envelope disassembly
def: "The controlled breakdown of the nuclear envelope during mitotic cell division." [GOC:bf]
relationship: part_of APO:P0000037 ! mitotic cell cycle
synonym: "mitotic nuclear envelope breakdown" EXACT []
synonym: "mitotic nuclear envelope degradation" EXACT []
xref: GO:0007077
[Term]
id: APO:R0000115
name: Reactome
def: "Reactome human pathway database" []
is_a: APO:R0000000 ! reference
comment: http://www.reactome.org/
[Term]
id: APO:B0000088
name: CYCD6;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F4C21_20" EXACT []
synonym: "F4C21.20" EXACT []
synonym: "Cyclin D6;1" EXACT []
synonym: "AT4G03270" EXACT []
xref: TAIR:gene:2125521
[Term]
id: APO:P0000042
name: achiasmate meiosis I
def: "The first division of meiosis in which homologous chromosomes that do not undergo meiotic recombination or form chiasmata are paired and segregated from each other, producing two daughter cells." [GOC:elh, PMID:10690419]
is_a: APO:P0000104 ! meiosis I
xref: GO:0000705
[Term]
id: APO:P0000016
name: M phase of mitotic cell cycle
def: "Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:mah, ISBN:0815316194]
is_a: APO:P0000038 ! M phase
relationship: part_of APO:P0000037 ! mitotic cell cycle
synonym: "M-phase of mitotic cell cycle" EXACT []
xref: GO:0000087
xref: Reactome:68886
[Term]
id: APO:B0000136
name: CYCD3;2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "K3G17.2" EXACT []
synonym: "K3G17_2" EXACT []
synonym: "CYCLIN D3;2" EXACT []
synonym: "AT5G67260" EXACT []
xref: TAIR:gene:3440647
[Term]
id: APO:B0000140
name: ADL1A
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000130 ! cell plate formation (sensu Magnoliophyta)
synonym: "AT5G42080" EXACT []
synonym: "MJC20_19" EXACT []
synonym: "AG68" EXACT []
synonym: "ARABIDOPSIS DYNAMIN-LIKE PROTEIN" EXACT []
synonym: "DRP1A" EXACT []
synonym: "MJC20.19" EXACT []
synonym: "DYNAMIN-RELATED PROTEIN 1A" EXACT []
xref: TAIR:gene:3685500
[Term]
id: APO:B0000029
name: AT4G37630.2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT4G37630" EXACT []
xref: TAIR:gene:1009022113
[Term]
id: APO:P0000105
name: meiotic prophase I
def: "Progression through prophase of meiosis I; divided into several stages." [GOC:mah]
is_a: APO:P0000268 ! prophase
relationship: part_of APO:P0000104 ! meiosis I
xref: GO:0007128
[Term]
id: APO:P0000002
name: mitotic sister chromatid segregation
def: "The process by which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai]
relationship: part_of APO:P0000069 ! mitosis
synonym: "mitotic chromosome segregation" EXACT []
synonym: "mitotic sister-chromatid adhesion release" NARROW []
xref: GO:0000070
xref: GO:0016359
[Term]
id: APO:R0000113
name: PubChem_Compound
def: "NCBI PubChem database of chemical structures" []
is_a: APO:R0000000 ! reference
comment: http://pubchem.ncbi.nlm.nih.gov/
[Term]
id: APO:P0000245
name: meiotic spindle disassembly
def: "The controlled breakdown of the spindle during a meiotic cell cycle." [GOC:ai]
is_a: APO:P0000029 ! meiotic spindle organization and biogenesis
synonym: "meiotic spindle breakdown" EXACT []
synonym: "meiotic spindle degradation" EXACT []
synonym: "spindle breakdown during meiosis" EXACT []
synonym: "spindle degradation during meiosis" EXACT []
synonym: "spindle disassembly during meiosis" EXACT []
xref: GO:0051229
[Term]
id: APO:R0000088
name: OMIM
def: "Mendelian Inheritance in Man" []
is_a: APO:R0000000 ! reference
comment: http://www3.ncbi.nlm.nih.gov/Omim/searchomim.html
[Term]
id: APO:P0000125
name: regulation of progression through preblastoderm mitotic cell cycle
def: "Any process that modulates the frequency, rate or extent of the progression through the preblastoderm mitotic cell cycle." [GOC:go_curators]
relationship: part_of APO:P0000129 ! regulation of progression through embryonic mitotic cell cycle
relationship: part_of APO:P0000175 ! preblastoderm mitotic cell cycle
synonym: "control of preblastoderm mitotic cell cycle progression" EXACT []
synonym: "modulation of preblastoderm mitotic cell cycle progression" EXACT []
synonym: "preblastoderm mitotic cell cycle control" EXACT []
synonym: "preblastoderm mitotic cell cycle modulation" EXACT []
synonym: "preblastoderm mitotic cell cycle regulation" EXACT []
synonym: "regulation of preblastoderm mitotic cell cycle" EXACT []
synonym: "regulation of preblastoderm mitotic cell cycle progression" EXACT []
synonym: "preblastoderm mitotic cell cycle regulator" RELATED []
xref: GO:0007347
[Term]
id: APO:P0000251
name: centrosome duplication
def: "The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized." [GOC:ai]
relationship: part_of APO:P0000096 ! centrosome cycle
synonym: "centrosome replication" EXACT []
xref: GO:0051298
[Term]
id: APO:B0000011
name: ICK5
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "KRP7" EXACT []
synonym: "ICN6" EXACT []
synonym: "AT1G49620" EXACT []
xref: TAIR:gene:1005867753
[Term]
id: APO:P0000210
name: negative regulation of progression through embryonic mitotic cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the embryonic mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000129 ! regulation of progression through embryonic mitotic cell cycle
is_a: APO:P0000208 ! negative regulation of progression through mitotic cell cycle
synonym: "negative regulation of embryonic mitotic cell cycle progression" EXACT []
xref: GO:0045976
[Term]
id: APO:B0000056
name: CYCP4;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT2G44740" EXACT []
synonym: "F16B22.23" EXACT []
xref: TAIR:gene:2042420
[Term]
id: APO:R0000128
name: SUBTILISTG
def: "Bacillus subtilis Genome Sequence Project" []
is_a: APO:R0000000 ! reference
comment: http://genolist.pasteur.fr/SubtiList/
[Term]
id: APO:R0000150
name: UM-BBD_enzymeID
def: "The University of Minnesota Biocatalysis/Biodegradation Database" []
is_a: APO:R0000000 ! reference
comment: http://umbbd.ahc.umn.edu/index.html
[Term]
id: APO:R0000094
name: PharmGKB_PA
def: "The Pharmacogenetics and Pharmacogenomics Knowledge Base" []
is_a: APO:R0000000 ! reference
comment: http://www.pharmgkb.org
[Term]
id: APO:P0000189
name: meiotic chromosome segregation
def: "The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle." [GOC:ai]
relationship: part_of APO:P0000103 ! meiosis
xref: GO:0045132
[Term]
id: APO:B0000053
name: CYCA3;3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G47220" EXACT []
synonym: "Cyclin A3;3" EXACT []
synonym: "F8G22.6" EXACT []
synonym: "F8G22_6" EXACT []
xref: TAIR:gene:2036760
[Term]
id: APO:R0000017
name: COG
def: "NCBI Clusters of Orthologous Groups" []
is_a: APO:R0000000 ! reference
comment: http://www.ncbi.nlm.nih.gov/COG/
[Term]
id: APO:P0000038
name: M phase
def: "Progression through M phase, the part of the cell cycle comprising nuclear division and cytokinesis." [ISBN:0815316194]
relationship: part_of APO:P0000056 ! cell cycle
synonym: "M-phase" EXACT []
xref: GO:0000279
[Term]
id: APO:P0000195
name: positive regulation of cyclin-dependent protein kinase activity
def: "Any process that activates or increases the frequency, rate or extent of CDK activity." [GOC:go_curators]
is_a: APO:P0000199 ! positive regulation of progression through cell cycle
is_a: APO:P0000009 ! regulation of cyclin-dependent protein kinase activity
synonym: "positive regulation of CDK activity" EXACT []
xref: GO:0045737
[Term]
id: APO:R0000148
name: TrEMBL
def: "UniProtKB-TrEMBL, a computer-annotated protein sequence database supplementing UniProtKB and containing the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database but not yet integrated in UniProtKB/Swiss-Prot" []
is_a: APO:R0000000 ! reference
comment: http://www.uniprot.org
[Term]
id: APO:R0000041
name: GermOnline
def: "GermOnline" []
is_a: APO:R0000000 ! reference
comment: http://www.germonline.org/
[Term]
id: APO:R0000158
name: WP
def: "Wormpep, database of proteins of C. elegans" []
is_a: APO:R0000000 ! reference
comment: http://www.wormbase.org/
[Term]
id: APO:R0000048
name: GR_protein
def: "Gramene: A Comparative Mapping Resource for Grains" []
is_a: APO:R0000000 ! reference
comment: http://www.gramene.org/
[Term]
id: APO:B0000148
name: CYCJ18
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "CYCLIN J18" EXACT []
synonym: "AT2G01905" EXACT []
xref: TAIR:gene:3713626
[Term]
id: APO:P0000045
name: meiotic strand invasion
def: "During meiosis, the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules." [GOC:elh, PMID:10915877]
relationship: part_of APO:P0000054 ! meiotic gene conversion
relationship: part_of APO:P0000108 ! meiotic recombination
synonym: "meiotic D-loop formation" RELATED []
xref: GO:0000708
[Term]
id: APO:P0000198
name: negative regulation of progression through cell cycle
def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the cell cycle." [GOC:go_curators]
is_a: APO:P0000004 ! regulation of progression through cell cycle
synonym: "negative regulation of cell cycle progression" EXACT []
xref: GO:0045786
[Term]
id: APO:R0000127
name: SUBTILIST
def: "Bacillus subtilis Genome Sequence Project" []
is_a: APO:R0000000 ! reference
comment: http://genolist.pasteur.fr/SubtiList/
[Term]
id: APO:R0000098
name: PIRSF
def: "PIR Superfamily Classification System" []
is_a: APO:R0000000 ! reference
comment: http://pir.georgetown.edu/pirsf/
[Term]
id: APO:P0000012
name: G1/S-specific transcription in mitotic cell cycle
def: "Any process that regulates transcription such that the target genes are transcribed during the G1/S phase of the mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000011 ! G1/S transition of mitotic cell cycle
xref: GO:0000083
xref: Reactome:69205
[Term]
id: APO:P0000299
name: meiotic sister chromatid arm separation
def: "The process by which sister chromatid arms are physically detached from each other during meiosis." [GOC:ai]
relationship: part_of APO:P0000301 ! meiotic sister chromatid separation
relationship: part_of APO:P0000104 ! meiosis I
xref: GO:0051755
[Term]
id: APO:P0000262
name: G1 phase
def: "Progression through G1 phase, one of two 'gap' phases in the cell cycle; G1 is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis." [GOC:ai]
relationship: part_of APO:P0000269 ! interphase
xref: GO:0051318
[Term]
id: APO:B0000138
name: CUL4
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "MDE13.3" EXACT []
synonym: "MDE13_3" EXACT []
synonym: "CULLIN4" EXACT []
synonym: "AT5G46210" EXACT []
xref: TAIR:gene:3440904
[Term]
id: APO:P0000017
name: mitotic prophase
def: "Progression through prophase, the initial stage of mitosis in which the chromosomes are condensed but are not yet attached to a mitotic spindle." [ISBN:0815316194]
is_a: APO:P0000268 ! prophase
relationship: part_of APO:P0000069 ! mitosis
xref: GO:0000088
xref: Reactome:68875
[Term]
id: APO:P0000235
name: negative regulation of transcription, meiotic
def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription during meiosis." [GOC:ai]
is_a: APO:P0000234 ! regulation of transcription, meiotic
synonym: "meiotic repression of transcription" EXACT []
synonym: "negative regulation of meiotic transcription" EXACT []
xref: GO:0051038
[Term]
id: APO:B0000066
name: AT2G18290.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000139 ! regulation of mitotic metaphase/anaphase transition
synonym: "AT2G18290" EXACT []
synonym: "T30D6_20" EXACT []
synonym: "T30D6.20" EXACT []
xref: TAIR:gene:2062105
[Term]
id: APO:P0000213
name: positive regulation of progression through preblastoderm mitotic cell cycle
def: "Any process that activates or increases the frequency, rate or extent of progression through the preblastoderm mitotic cell cycle." [GOC:go_curators]
is_a: APO:P0000211 ! positive regulation of mitotic cell cycle, embryonic
is_a: APO:P0000125 ! regulation of progression through preblastoderm mitotic cell cycle
synonym: "positive regulation of preblastoderm mitotic cell cycle progression" EXACT []
xref: GO:0046002
[Term]
id: APO:U0000006
name: transcript
def: "An RNA synthesized on a DNA or RNA template by an RNA polymerase." [SO:0000673]
is_a: APO:U0000003 ! biopolymer
xref: SO:0000673
[Term]
id: APO:P0000201
name: positive regulation of meiosis
def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators]
is_a: APO:P0000178 ! regulation of meiosis
xref: GO:0045836
[Term]
id: APO:B0000030
name: AT4G02570.2
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000056 ! cell cycle
synonym: "AT4G02570" EXACT []
xref: TAIR:gene:1009022197
[Term]
id: APO:P0000094
name: mitotic G2 checkpoint
def: "A signal transduction-based surveillance mechanism that ensures accurate chromosome segregation by preventing entry into mitosis in the presence of damaged DNA." [GOC:mah, PMID:10856933, PMID:11406266]
is_a: APO:P0000092 ! mitotic checkpoint
is_a: APO:P0000159 ! G2/M transition DNA damage checkpoint
synonym: "mitotic G2/M transition DNA damage checkpoint" EXACT []
xref: GO:0007095
[Term]
id: APO:P0000287
name: regulation of progression through meiotic cell cycle
def: "Any process that modulates the rate or extent of progression through the mitotic cell cycle." [GOC:ai]
is_a: APO:P0000004 ! regulation of progression through cell cycle
relationship: part_of APO:P0000265 ! meiotic cell cycle
synonym: "control of meiotic cell cycle progression" EXACT []
synonym: "meiotic cell cycle control" EXACT []
synonym: "meiotic cell cycle modulation" EXACT []
synonym: "meiotic cell cycle regulation" EXACT []
synonym: "modulation of meiotic cell cycle progression" EXACT []
synonym: "regulation of meiotic cell cycle" EXACT []
synonym: "regulation of meiotic cell cycle progression" EXACT []
synonym: "meiotic cell cycle regulator" RELATED []
xref: GO:0051445
[Term]
id: APO:B0000147
name: AML1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000201 ! positive regulation of meiosis
synonym: "ARABIDOPSIS MEI2-LIKE PROTEIN 1" EXACT []
synonym: "AT5G61960" EXACT []
xref: TAIR:gene:3713554
[Term]
id: APO:P0000148
name: positive regulation of septation initiation signaling
def: "Any process that activates or increases the frequency, rate or extent of septation initiation signaling." [GOC:mah]
is_a: APO:P0000146 ! regulation of septation initiation signaling
synonym: "positive regulation of septation initiation network" EXACT []
synonym: "positive regulation of septation initiation signalling" EXACT []
xref: GO:0031031
[Term]
id: APO:B0000106
name: KRP3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
synonym: "K24G6_15" EXACT []
synonym: "KIP-RELATED PROTEIN 3" EXACT []
synonym: "AT5G48820" EXACT []
synonym: "K24G6.15" EXACT []
xref: TAIR:gene:2156543
[Term]
id: APO:R0000006
name: BIOMD
def: "BioModels Database" []
is_a: APO:R0000000 ! reference
comment: http://www.ebi.ac.uk/biomodels/
[Term]
id: APO:R0000101
name: POC
def: "Plant Ontology Consortium " []
is_a: APO:R0000000 ! reference
[Term]
id: APO:B0000115
name: CYCA2;3
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT1G15570" EXACT []
synonym: "CYCLIN A2;3" EXACT []
synonym: "T16N11.8" EXACT []
synonym: "T16N11_8" EXACT []
xref: TAIR:gene:2196562
[Term]
id: APO:B0000074
name: AT3G24730.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000069 ! mitosis
synonym: "AT3G24730" EXACT []
synonym: "K7P8.2" EXACT []
xref: TAIR:gene:2087272
[Term]
id: APO:P0000275
name: G2 phase of meiotic cell cycle
def: "Progression through G2 phase, one of two 'gap' phases in the meiotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of meiosis." [GOC:ai]
is_a: APO:P0000263 ! G2 phase
relationship: part_of APO:P0000272 ! interphase of meiotic cell cycle
xref: GO:0051331
[Term]
id: APO:R0000100
name: PO
def: "Plant Ontology Consortium Database" []
is_a: APO:R0000000 ! reference
comment: http://www.plantontology.org/
[Term]
id: APO:P0000100
name: cytokinesis after meiosis I
def: "The processes resulting in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells." [GOC:ai]
relationship: part_of APO:P0000271 ! M phase of meiotic cell cycle
xref: GO:0007110
[Term]
id: APO:B0000048
name: AT1G77390.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "F2P24.10" EXACT []
synonym: "AT1G77390" EXACT []
synonym: "F2P24_10" EXACT []
xref: TAIR:gene:2031406
[Term]
id: APO:P0000185
name: meiotic spindle stabilization
def: "Maintenance of spindle integrity during M phase of meiosis." [GOC:go_curators]
relationship: part_of APO:P0000029 ! meiotic spindle organization and biogenesis
xref: GO:0043147
[Term]
id: APO:P0000023
name: G1-specific transcription in mitotic cell cycle
def: "Any process that regulates transcription such that the target genes are transcribed during the G1 phase of the mitotic cell cycle." [GOC:mah]
relationship: part_of APO:P0000010 ! G1 phase of mitotic cell cycle
xref: GO:0000114
[Term]
id: APO:R0000162
name: PSI-MOD
def: "Proteomics Standards Initiative protein modification ontology" []
is_a: APO:R0000000 ! reference
comment: http://psidev.sourceforge.net/mod/
[Term]
id: APO:P0000183
name: meiotic metaphase I plate congression
def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I." [GOC:cab1, PMID:10809666]
is_a: APO:P0000257 ! meiotic metaphase plate congression
relationship: part_of APO:P0000191 ! homologous chromosome segregation
xref: GO:0043060
[Term]
id: APO:R0000121
name: SGD
def: "Saccharomyces Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.yeastgenome.org/
[Term]
id: APO:P0000269
name: interphase
def: "Progression through interphase, the stage of cell cycle between successive rounds of chromosome segregation. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [http:www.onelook.com]
relationship: part_of APO:P0000056 ! cell cycle
synonym: "karyostasis" EXACT []
synonym: "resting phase" BROAD []
xref: GO:0051325
[Term]
id: APO:B0000089
name: TEB
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000163 ! G2/M transition checkpoint
synonym: "TEBICHI" EXACT []
synonym: "AT4G32700" EXACT []
synonym: "F4D11.100" EXACT []
synonym: "F4D11_100" EXACT []
xref: TAIR:gene:2125676
[Term]
id: APO:P0000110
name: meiotic anaphase I
def: "Progression through anaphase of meiosis I; analogous to mitotic anaphase." [GOC:mah]
is_a: APO:P0000266 ! anaphase
relationship: part_of APO:P0000104 ! meiosis I
xref: GO:0007133
[Term]
id: APO:P0000282
name: positive regulation of ubiquitin ligase activity during mitotic cell cycle
def: "Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai]
is_a: APO:P0000283 ! regulation of ubiquitin ligase activity during mitotic cell cycle
synonym: "activation of ubiquitin ligase activity during mitotic cell cycle" NARROW []
synonym: "mitotic SCF complex activator" NARROW []
synonym: "mitotic ubiquitin ligase activator" NARROW []
xref: GO:0051437
[Term]
id: APO:B0000009
name: SOG1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000178 ! regulation of meiosis
relationship: participates_in APO:P0000007 ! DNA damage checkpoint
synonym: "SUPPRESSOR OF GAMMA RADIATION" EXACT []
xref: TAIR:gene:1005867677
[Term]
id: APO:P0000172
name: G2/M-specific positive regulation of cyclin-dependent protein kinase activity
def: "Any process that activates or increases the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah]
is_a: APO:P0000195 ! positive regulation of cyclin-dependent protein kinase activity
is_a: APO:P0000170 ! G2/M-specific regulation of cyclin-dependent protein kinase activity
xref: GO:0031662
[Term]
id: APO:R0000038
name: GeneDB_Spombe
def: "GeneDB_Spombe" []
is_a: APO:R0000000 ! reference
comment: http://www.genedb.org/genedb/pombe/
[Term]
id: APO:P0000296
name: cell cycle switching, mitotic to meiotic cell cycle
def: "The process by which a cell switches cell cycle mode from mitotic to meiotic division." [GOC:ai]
is_a: APO:P0000294 ! regulation of cell cycle
synonym: "conversion to meiotic cell cycle" EXACT []
synonym: "entry into meiotic cell cycle" EXACT []
synonym: "initiation of meiotic cell cycle" EXACT []
synonym: "cell cycle switching, mitotis to meiosis" NARROW []
synonym: "conversion to meiosis" NARROW []
synonym: "entry into meiosis" NARROW []
synonym: "initiation of meiosis" NARROW []
synonym: "meiotic entry" NARROW []
xref: GO:0051728
xref: GO:0042061
[Term]
id: APO:P0000236
name: positive regulation of transcription, meiotic
def: "Any process that activates or increases the frequency, rate or extent of transcription during meiosis." [GOC:ai]
is_a: APO:P0000234 ! regulation of transcription, meiotic
synonym: "positive regulation of meiotic transcription" EXACT []
xref: GO:0051039
[Term]
id: APO:R0000030
name: ENSEMBL
def: "Database of automatically annotated genomic data" []
is_a: APO:R0000000 ! reference
comment: http://www.ensembl.org/
[Term]
id: APO:R0000106
name: Prosite
def: "Prosite. Database of protein families and domains" []
is_a: APO:R0000000 ! reference
comment: http://www.expasy.ch/prosite/
[Term]
id: APO:B0000099
name: AT5G11300
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
xref: TAIR:gene:2148051
[Term]
id: APO:B0000091
name: AESP
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000254 ! meiotic chromosome separation
synonym: "F7H19_150" EXACT []
synonym: "AT4G22970" EXACT []
synonym: "ARABIDOPSIS HOMOLOG OF SEPARASE" EXACT []
synonym: "F7H19.150" EXACT []
xref: TAIR:gene:2127237
[Term]
id: APO:R0000135
name: TGD_REF
def: "Tetrahymena Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://www.ciliate.org/
[Term]
id: APO:R0000118
name: RGD
def: "Rat Genome Database" []
is_a: APO:R0000000 ! reference
comment: http://rgd.mcw.edu/
[Term]
id: APO:P0000192
name: meiotic sister chromatid segregation
def: "The process by which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194]
relationship: part_of APO:P0000189 ! meiotic chromosome segregation
relationship: part_of APO:P0000112 ! meiosis II
synonym: "meiosis II, chromosome segregation" EXACT []
xref: GO:0045144
[Term]
id: APO:P0000246
name: meiotic spindle elongation
def: "The lengthening of the distance between poles of the spindle during a meiotic cell cycle." [GOC:ai]
relationship: part_of APO:P0000029 ! meiotic spindle organization and biogenesis
synonym: "spindle elongation during meiosis" EXACT []
xref: GO:0051232
[Term]
id: APO:P0000103
name: meiosis
def: "The specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiosis occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations." [PMID:9334324]
relationship: part_of APO:P0000271 ! M phase of meiotic cell cycle
xref: GO:0007126
[Term]
id: APO:P0000027
name: establishment of mitotic spindle orientation
def: "The processes that set the alignment of mitotic spindle relative to other cellular structures." [GOC:ems]
is_a: APO:P0000177 ! establishment of mitotic spindle localization
synonym: "establishment of spindle orientation during mitosis" EXACT []
synonym: "mitotic spindle orientation" EXACT []
synonym: "orienting of mitotic spindle" EXACT []
synonym: "mitotic spindle orientation (sensu Fungi)" NARROW []
synonym: "mitotic spindle orientation (sensu Saccharomyces)" NARROW []
xref: GO:0000132
xref: GO:0030607
xref: GO:0030609
[Term]
id: APO:P0000142
name: cell cycle arrest in response to nitrogen starvation
def: "The processes that lead to a halt in cell cycle progression (cessation of cell cycle transitions) as a result of deprivation of nitrogen." [GOC:vw]
is_a: APO:P0000057 ! cell cycle arrest
xref: GO:0030996
[Term]
id: APO:R0000057
name: IMGT_LIGM
def: "Immunogenetics database, immunoglobulins and T-cell receptors" []
is_a: APO:R0000000 ! reference
comment: http://imgt.cines.fr
[Term]
id: APO:B0000028
name: AT3G05327.1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT3G05327" EXACT []
xref: TAIR:gene:1009021962
[Term]
id: APO:R0000109
name: PseudoCAP
def: "Pseudomonas Genome Project" []
is_a: APO:R0000000 ! reference
comment: http://v2.pseudomonas.com/
[Term]
id: APO:P0000161
name: S-M checkpoint
def: "A cell cycle checkpoint which halts replication in response to nucleotide depletion." [GOC:vw]
is_a: APO:P0000160 ! intra-S DNA damage checkpoint
xref: GO:0031574
[Term]
id: APO:P0000135
name: female meiotic chromosome movement towards spindle pole
def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis." [GOC:ai]
is_a: APO:P0000134 ! meiotic chromosome movement towards spindle pole
relationship: part_of APO:P0000132 ! female meiosis chromosome segregation
synonym: "chromosome movement towards spindle pole during female meiosis" EXACT []
synonym: "female meiotic chromosome movement to spindle pole" EXACT []
synonym: "female meiotic chromosome movement" BROAD []
xref: GO:0016345
[Term]
id: APO:B0000081
name: CYCP1;1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "AT3G63120" EXACT []
synonym: "T20O10.220" EXACT []
xref: TAIR:gene:2099191
[Term]
id: APO:P0000136
name: male meiotic chromosome movement towards spindle pole
def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis." [GOC:ai]
is_a: APO:P0000134 ! meiotic chromosome movement towards spindle pole
relationship: part_of APO:P0000065 ! male meiosis chromosome segregation
synonym: "chromosome movement towards spindle pole during male meiosis" EXACT []
synonym: "male meiotic chromosome movement to spindle pole" EXACT []
synonym: "male meiotic chromosome movement" BROAD []
xref: GO:0016346
[Term]
id: APO:R0000049
name: GR_REF
def: "Gramene: A Comparative Mapping Resource for Grains" []
is_a: APO:R0000000 ! reference
comment: http://www.gramene.org/
[Term]
id: APO:B0000157
name: CKS1
is_a: APO:U0000004 ! gene
relationship: participates_in APO:P0000037 ! mitotic cell cycle
relationship: participates_in APO:P0000004 ! regulation of progression through cell cycle
synonym: "P10CKS1AT" EXACT []
synonym: "CKS1AT" EXACT []
synonym: "AT2G27960" EXACT []
synonym: "CATALYTIC SUBUNIT OF CYCLIN-DEPENDENT KINASE" EXACT []
xref: TAIR:gene:4370594
[Term]
id: APO:P0000154
name: cell size control checkpoint
def: "Any cell cycle checkpoint that delays or arrests cell cycle progression until cells have reached a critical size." [GOC:mah]
is_a: APO:P0000005 ! cell cycle checkpoint
xref: GO:0031567
[Term]
id: APO:P0000270
name: telophase
def: "Progression through telophase, the last stage of chromosome segregation in the cell cycle. Canonically, telophase begins when the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [http:www.onelook.com]
relationship: part_of APO:P0000038 ! M phase
xref: GO:0051326
[Term]
id: APO:R0000069
name: MaizeGDB
def: "MaizeGDB" []
is_a: APO:R0000000 ! reference
comment: http://www.maizegdb.org
[Typedef]
id: derives_from
name: derives_from
def: "Derivation on the instance level (*derives_from*) holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. We say that one class C derives_from class C' if instances of C are connected to instances of C' via some chain of instance-level derivation relations. Example: osteocyte derives_from osteoblast. Formally: C derives_immediately_from C' if and only if: given any c and any t, if c instantiates C at time t, then there is some c' and some t', such that c' instantiates C' at t' and t' earlier-than t and c *derives_from* c'. C derives_from C' if and only if: there is an chain of immediate derivation relations connecting C to C'." [PMID:15892874]
comment: Derivation as a relation between instances. The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant.
is_a: relationship ! relationship
is_transitive: true
xref: OBO_REL:derives_from
[Typedef]
id: agent_in
name: agent_in
is_a: relationship ! relationship
xref: OBO_REL:agent_in
[Typedef]
id: relationship
name: relationship
def: "A relationship between two classes (terms). Relationships between classes are expressed in terms of relations on underlying instances." []
xref: OBO_REL:relationship
[Typedef]
id: has_proper_part
name: has_proper_part
is_a: part_of ! part_of
is_transitive: true
xref: OBO_REL:has_proper_part
[Typedef]
id: has_agent
name: has_agent
def: "As for has_participant, but with the additional condition that the component instance is causally active in the relevant process" [PMID:15892874]
is_a: relationship ! relationship
xref: OBO_REL:has_agent
[Typedef]
id: has_integral_part
name: has_integral_part
is_a: part_of ! part_of
is_reflexive: true
is_anti_symmetric: true
is_transitive: true
xref: OBO_REL:has_integral_part
[Typedef]
id: catalyses
name: catalyses
def: "C catalyses P if and only if for all c (catalyst) belonging to C, exists a p (belonging to P) which chemical reaction rate is increased by c." [APO:ea]
comment: C inhibits P if and only if for all c (inhibitor) belonging to C, exists a p (belonging to P) which chemical reaction rate is reduced or prevented by c.
synonym: "activates" EXACT []
is_a: relationship ! relationship
xref: APO_REL:catalyses
[Typedef]
id: transformation_of
name: transformation_of
def: "Relation between two classes, in which instances retain their identity yet change their classification by virtue of some kind of transformation. Formally: C transformation_of C' if and only if given any c and any t, if c instantiates C at time t, then for some t', c instantiates C' at t' and t' earlier t, and there is no t2 such that c instantiates C at t2 and c instantiates C' at t2." [PMID:15892874]
comment: When an embryonic oenocyte (a type of insect cell) is transformed into a larval oenocyte, one and the same continuant entity preserves its identity while instantiating distinct classes at distinct times. The class-level relation transformation_of obtains between continuant classes C and C1 wherever each instance of the class C is such as to have existed at some earlier time as an instance of the distinct class C1 (see Figure 2 in paper). This relation is illustrated first of all at the molecular level of granularity by the relation between mature RNA and the pre-RNA from which it is processed, or between (UV-induced) thymine-dimer and thymine dinucleotide. At coarser levels of granularity it is illustrated by the transformations involved in the creation of red blood cells, for example, from reticulocyte to erythrocyte, and by processes of development, for example, from larva to pupa, or from (post-gastrular) embryo to fetus or from child to adult. It is also manifest in pathological transformations, for example, of normal colon into carcinomatous colon. In each such case, one and the same continuant entity instantiates distinct classes at different times in virtue of phenotypic changes.
is_a: relationship ! relationship
is_transitive: true
xref: OBO_REL:transformation_of
[Typedef]
id: located_in
name: located_in
def: "C located_in C' if and only if: given any c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c *located_in* c'. (Here *located_in* is the instance-level location relation.)" [PMID:15892874]
comment: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
is_a: relationship ! relationship
is_reflexive: true
is_transitive: true
xref: OBO_REL:located_in
[Typedef]
id: is_a
name: is_a
builtin: true
def: "For continuants: C is_a C' if and only if: given any c that instantiates C at a time t, c instantiates C' at t. For processes: P is_a P' if and only if: that given any p that instantiates P, then p instantiates P'." [PMID:15892874]
comment: The is_a relationship is considered axiomatic by the obo file format specification, and by OWL
synonym: "is_subtype_of" EXACT []
is_reflexive: true
is_anti_symmetric: true
is_transitive: true
xref: OBO_REL:is_a
xref: owl:subClassOf
[Typedef]
id: location_of
name: location_of
is_a: relationship ! relationship
is_reflexive: true
is_transitive: true
xref: OBO_REL:location_of
[Typedef]
id: association
name: association
def: "C in association with C' produces C'' if and only if for all c belonging to C and c' belongin to C', exists a c'' (belonging to C'') which is the result of the reversible union between c and c'." [APO:ea]
comment: Ternary relationship. See http://www.w3.org/TR/swbp-n-aryRelations/ for the OWL equivalent. The dissociation is a reversible splitting into simpler entities.
is_a: relationship ! relationship
xref: APO_REL:association
[Typedef]
id: improper_part_of
name: improper_part_of
def: "As for part_of, with the additional constraint that subject and object may be identical" [PMID:15892874]
is_a: part_of ! part_of
is_reflexive: true
is_transitive: true
xref: OBO_REL:improper_part_of
[Typedef]
id: part_of
name: part_of
def: "For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation.)" [PMID:15892874]
comment: Parthood as a relation between instances: The primitive instance-level relation p part_of p1 is illustrated in assertions such as: this instance of rhodopsin mediated phototransduction part_of this instance of visual perception. This relation satisfies at least the following standard axioms of mereology: reflexivity (for all p, p part_of p); anti-symmetry (for all p, p1, if p part_of p1 and p1 part_of p then p and p1 are identical); and transitivity (for all p, p1, p2, if p part_of p1 and p1 part_of p2, then p part_of p2). Analogous axioms hold also for parthood as a relation between spatial regions. For parthood as a relation between continuants, these axioms need to be modified to take account of the incorporation of a temporal argument. Thus for example the axiom of transitivity for continuants will assert that if c part_of c1 at t and c1 part_of c2 at t, then also c part_of c2 at t. Parthood as a relation between classes: To define part_of as a relation between classes we again need to distinguish the two cases of continuants and processes, even though the explicit reference to instants of time now falls away. For continuants, we have C part_of C1 if and only if any instance of C at any time is an instance-level part of some instance of C1 at that time, as for example in: cell nucleus part_ of cell.
is_a: relationship ! relationship
is_reflexive: true
is_anti_symmetric: true
is_transitive: true
xref: OBO_REL:part_of
[Typedef]
id: has_part
name: has_part
is_a: relationship ! relationship
is_reflexive: true
is_anti_symmetric: true
is_transitive: true
xref: OBO_REL:has_part
[Typedef]
id: precedes
name: precedes
is_a: relationship ! relationship
is_transitive: true
xref: OBO_REL:precedes
[Typedef]
id: derived_into
name: derived_into
is_a: relationship ! relationship
is_transitive: true
xref: OBO_REL:derived_into
[Typedef]
id: transformed_into
name: transformed_into
is_a: relationship ! relationship
is_transitive: true
xref: OBO_REL:transformed_into
[Typedef]
id: participates_in
name: participates_in
def: "C participates_in P if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [APO:ea]
is_a: relationship ! relationship
inverse_of: has_participant ! has participant
xref: OBO_REL:participates_in
xref: APO_REL:participates_in
[Typedef]
id: degradates
name: degradates
def: "C is degradated (into NIL) if and only if for all c belonging to C, exists c', c'', ... (belonging to C', C'', ...) which are the result of any undesired breakdown of c with impairment or loss of its characteristic properties." [APO:ea]
comment: NIL entity must be created.
synonym: "decomposition" EXACT []
synonym: "catabolism" EXACT []
is_a: relationship ! relationship
xref: APO_REL:degradates
[Typedef]
id: has_improper_part
name: has_improper_part
is_a: part_of ! part_of
is_reflexive: true
is_transitive: true
xref: OBO_REL:has_improper_part
[Typedef]
id: proper_part_of
name: proper_part_of
def: "As for part_of, with the additional constraint that subject and object are distinct" [PMID:15892874]
is_a: part_of ! part_of
is_transitive: true
xref: OBO_REL:proper_part_of
[Typedef]
id: contains
name: contains
is_a: relationship ! relationship
xref: OBO_REL:contains
[Typedef]
id: preceded_by
name: preceded_by
def: "P preceded_by P' if and only if: given any process p that instantiates P at a time t, there is some process p' such that p' instantiates P' at time t', and t' is earlier than t. " [PMID:15892874]
comment: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
is_a: relationship ! relationship
is_transitive: true
xref: OBO_REL:preceded_by
[Typedef]
id: has_participant
name: has_participant
def: "P has_participant C if and only if: given any process p that instantiates P there is some continuant c, and some time t, such that: c instantiates C at t and c participates in p at t" [PMID:15892874]
comment: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
is_a: relationship ! relationship
xref: OBO_REL:has_participant
[Typedef]
id: contained_in
name: contained_in
def: "C contained_in C' if and only if: given any instance c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c located_in c' at t, and it is not the case that c *overlaps* c' at t. (c' is a conduit or cavity.)" [PMID:15892874]
comment: Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):
is_a: relationship ! relationship
xref: OBO_REL:contained_in
[Typedef]
id: interacts_with
name: interacts_with
def: "C interacts_with C' if and only if for all c belonging to C, exists a c' (belonging to C') which plays a role with c'." [APO:ea]
is_a: relationship ! relationship
is_symmetric: true
is_transitive: true
xref: APO_REL:interacts_with
[Typedef]
id: adjacent_to
name: adjacent_to
def: "C adjacent to C' if and only if: given any instance c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c and c' are in spatial proximity" [PMID:15892874]
comment: Note that adjacent_to as thus defined is not a symmetric relation, in contrast to its instance-level counterpart. For it can be the case that Cs are in general such as to be adjacent to instances of C1 while no analogous statement holds for C1s in general in relation to instances of C. Examples are: nuclear membrane adjacent_to cytoplasm; seminal vesicle adjacent_to urinary bladder; ovary adjacent_to parietal pelvic peritoneum
is_a: relationship ! relationship
xref: OBO_REL:adjacent_to
[Typedef]
id: integral_part_of
name: integral_part_of
def: "C integral_part_of C' if and only if: C part_of C' AND C' has_part C" [PMID:15892874]
is_a: part_of ! part_of
is_reflexive: true
is_anti_symmetric: true
is_transitive: true
xref: OBO_REL:integral_part_of
[Typedef]
id: has_source
name: has_source
is_a: relationship
def: "o has_source O where o is a gene or gene product and O an organism." [APO:ea]
created_by: erick_antezana
creation_date: 2008-04-13T01:32:36Z