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<!-- Title: g Pages: 1 -->
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<title>g</title>
<polygon fill="white" stroke="white" points="-4,4 -4,-164 1164,-164 1164,4 -4,4"/>
<g id="clust1" class="cluster"><title>cluster_0</title>
<polygon fill="none" stroke="#f7f7f7" points="8,-100 8,-152 1039,-152 1039,-100 8,-100"/>
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<!-- Hef1a -->
<g id="node1" class="node"><title>Hef1a</title>
<polygon fill="#ca0020" stroke="#ca0020" points="52,-138 16,-138 16,-108 34,-108 34,-114 52,-114 52,-108 70,-126 52,-144 52,-138"/>
<text text-anchor="middle" x="43" y="-122.3" font-family="Times,serif" font-size="14.00" fill="#f7f7f7">Hef1a</text>
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<!-- Gal4VP16 -->
<g id="node5" class="node"><title>Gal4VP16</title>
<polygon fill="#0571b0" stroke="#0571b0" points="166,-138 106,-138 106,-114 166,-114 166,-108 184,-126 166,-144 166,-138"/>
<text text-anchor="middle" x="145" y="-122.3" font-family="Times,serif" font-size="14.00" fill="#f7f7f7">Gal4-VP16</text>
</g>
<!-- Hef1a->Gal4VP16 -->
<g id="edge1" class="edge"><title>Hef1a->Gal4VP16</title>
<path fill="none" stroke="black" d="M70.0128,-126C79.3624,-126 90.1786,-126 100.605,-126"/>
<polyline fill="none" stroke="black" points="105.684,-126 100.684,-126 "/>
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<!-- TRE -->
<g id="node2" class="node"><title>TRE</title>
<polygon fill="#ca0020" stroke="#ca0020" points="813,-138 777,-138 777,-108 795,-108 795,-114 813,-114 813,-108 831,-126 813,-144 813,-138"/>
<text text-anchor="middle" x="804" y="-122.3" font-family="Times,serif" font-size="14.00" fill="#f7f7f7">TRE</text>
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<!-- DeltamCherry -->
<g id="node8" class="node"><title>DeltamCherry</title>
<polygon fill="#0571b0" stroke="#0571b0" points="1012.5,-138 935.5,-138 935.5,-114 1012.5,-114 1012.5,-108 1030.5,-126 1012.5,-144 1012.5,-138"/>
<text text-anchor="middle" x="983" y="-122.3" font-family="Times,serif" font-size="14.00" fill="#f7f7f7">DeltamCherry</text>
</g>
<!-- TRE->DeltamCherry -->
<g id="edge7" class="edge"><title>TRE->DeltamCherry</title>
<path fill="none" stroke="black" d="M831.117,-126C857.132,-126 897.779,-126 930.333,-126"/>
<polyline fill="none" stroke="black" points="935.484,-126 930.484,-126 "/>
</g>
<!-- UAS -->
<g id="node3" class="node"><title>UAS</title>
<polygon fill="#ca0020" stroke="#ca0020" points="280,-138 244,-138 244,-108 262,-108 262,-114 280,-114 280,-108 298,-126 280,-144 280,-138"/>
<text text-anchor="middle" x="271" y="-122.3" font-family="Times,serif" font-size="14.00" fill="#f7f7f7">UAS</text>
</g>
<!-- LacI -->
<g id="node6" class="node"><title>LacI</title>
<polygon fill="#0571b0" stroke="#0571b0" points="394,-138 358,-138 358,-114 394,-114 394,-108 412,-126 394,-144 394,-138"/>
<text text-anchor="middle" x="385" y="-122.3" font-family="Times,serif" font-size="14.00" fill="#f7f7f7">LacI</text>
</g>
<!-- UAS->LacI -->
<g id="edge3" class="edge"><title>UAS->LacI</title>
<path fill="none" stroke="black" d="M298.259,-126C314.548,-126 335.567,-126 352.717,-126"/>
<polyline fill="none" stroke="black" points="357.905,-126 352.905,-126 "/>
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<!-- Hef1aLacOid -->
<g id="node4" class="node"><title>Hef1aLacOid</title>
<polygon fill="#ca0020" stroke="#ca0020" points="525.5,-138 448.5,-138 448.5,-108 466.5,-108 466.5,-114 525.5,-114 525.5,-108 543.5,-126 525.5,-144 525.5,-138"/>
<text text-anchor="middle" x="496" y="-122.3" font-family="Times,serif" font-size="14.00" fill="#f7f7f7">Hef1a-LacOid</text>
</g>
<!-- rtTA3 -->
<g id="node7" class="node"><title>rtTA3</title>
<polygon fill="#0571b0" stroke="#0571b0" points="655,-138 619,-138 619,-114 655,-114 655,-108 673,-126 655,-144 655,-138"/>
<text text-anchor="middle" x="646" y="-122.3" font-family="Times,serif" font-size="14.00" fill="#f7f7f7">rtTA3</text>
</g>
<!-- Hef1aLacOid->rtTA3 -->
<g id="edge5" class="edge"><title>Hef1aLacOid->rtTA3</title>
<path fill="none" stroke="black" d="M543.828,-126C566.625,-126 593.416,-126 613.701,-126"/>
<polyline fill="none" stroke="black" points="618.711,-126 613.711,-126 "/>
</g>
<!-- Gal4VP16->UAS -->
<g id="edge2" class="edge"><title>Gal4VP16->UAS</title>
<path fill="none" stroke="black" d="M184.216,-126C201.757,-126 222.292,-126 238.872,-126"/>
<polyline fill="none" stroke="black" points="243.883,-126 238.883,-126 "/>
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<!-- Gal4VP16protein -->
<g id="node14" class="node"><title>Gal4VP16protein</title>
<ellipse fill="#92c5de" stroke="#92c5de" cx="271" cy="-72" rx="50.8918" ry="18"/>
<text text-anchor="middle" x="271" y="-68.3" font-family="Times,serif" font-size="14.00" fill="#0571b0">Gal4-VP16</text>
</g>
<!-- Gal4VP16->Gal4VP16protein -->
<g id="edge8" class="edge"><title>Gal4VP16->Gal4VP16protein</title>
<path fill="none" stroke="black" d="M184.216,-109.358C198.459,-103.155 214.676,-96.0926 229.147,-89.7908"/>
<polygon fill="black" stroke="black" points="230.595,-92.9777 238.366,-85.776 227.8,-86.5598 230.595,-92.9777"/>
</g>
<!-- LacI->Hef1aLacOid -->
<g id="edge4" class="edge"><title>LacI->Hef1aLacOid</title>
<path fill="none" stroke="black" d="M412.108,-126C421.418,-126 432.261,-126 442.976,-126"/>
<polyline fill="none" stroke="black" points="448.218,-126 443.218,-126 "/>
</g>
<!-- LacIprotein -->
<g id="node12" class="node"><title>LacIprotein</title>
<ellipse fill="#92c5de" stroke="#92c5de" cx="496" cy="-72" rx="27" ry="18"/>
<text text-anchor="middle" x="496" y="-68.3" font-family="Times,serif" font-size="14.00" fill="#0571b0">LacI</text>
</g>
<!-- LacI->LacIprotein -->
<g id="edge10" class="edge"><title>LacI->LacIprotein</title>
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<!-- rtTA3->TRE -->
<g id="edge6" class="edge"><title>rtTA3->TRE</title>
<path fill="none" stroke="black" d="M673.111,-126C700.22,-126 742.634,-126 771.565,-126"/>
<polyline fill="none" stroke="black" points="776.804,-126 771.804,-126 "/>
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<!-- rtTA3protein -->
<g id="node13" class="node"><title>rtTA3protein</title>
<ellipse fill="#92c5de" stroke="#92c5de" cx="804" cy="-72" rx="32.4942" ry="18"/>
<text text-anchor="middle" x="804" y="-68.3" font-family="Times,serif" font-size="14.00" fill="#0571b0">rtTA3</text>
</g>
<!-- rtTA3->rtTA3protein -->
<g id="edge14" class="edge"><title>rtTA3->rtTA3protein</title>
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<!-- product -->
<g id="node9" class="node"><title>product</title>
<ellipse fill="#f4a582" stroke="#f4a582" cx="1133" cy="-126" rx="27" ry="18"/>
</g>
<!-- DeltamCherry->product -->
<g id="edge18" class="edge"><title>DeltamCherry->product</title>
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<!-- repression -->
<g id="node10" class="node"><title>repression</title>
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<text text-anchor="middle" x="646" y="-68.3" font-family="Times,serif" font-size="14.00">LacI repression</text>
</g>
<!-- repression->Hef1aLacOid -->
<g id="edge12" class="edge"><title>repression->Hef1aLacOid</title>
<path fill="none" stroke="black" d="M605.921,-86.2585C588.359,-92.6663 567.392,-100.316 548.565,-107.186"/>
<polygon fill="black" stroke="black" points="546.481,-113.268 543.054,-103.874 544.933,-103.189 548.36,-112.583 546.481,-113.268"/>
<polyline fill="none" stroke="black" points="543.828,-108.914 548.525,-107.2 "/>
</g>
<!-- combination -->
<g id="node11" class="node"><title>combination</title>
<ellipse fill="#92c5de" stroke="#92c5de" cx="983" cy="-72" rx="87.1846" ry="18"/>
<text text-anchor="middle" x="983" y="-68.3" font-family="Times,serif" font-size="14.00" fill="#0571b0">rtTA3 + Doxycycline</text>
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<!-- combination->TRE -->
<g id="edge16" class="edge"><title>combination->TRE</title>
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<!-- LacIprotein->repression -->
<g id="edge11" class="edge"><title>LacIprotein->repression</title>
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<polygon fill="black" stroke="black" points="570.354,-75.5001 580.354,-72 570.354,-68.5001 570.354,-75.5001"/>
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<!-- rtTA3protein->combination -->
<g id="edge15" class="edge"><title>rtTA3protein->combination</title>
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<polygon fill="black" stroke="black" points="885.568,-75.5001 895.568,-72 885.568,-68.5001 885.568,-75.5001"/>
</g>
<!-- Gal4VP16protein->UAS -->
<g id="edge9" class="edge"><title>Gal4VP16protein->UAS</title>
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<polygon fill="black" stroke="black" points="267.5,-97.7901 271,-107.79 274.5,-97.7902 267.5,-97.7901"/>
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<!-- IPTG -->
<g id="node15" class="node"><title>IPTG</title>
<ellipse fill="#92c5de" stroke="#92c5de" cx="496" cy="-18" rx="30.5947" ry="18"/>
<text text-anchor="middle" x="496" y="-14.3" font-family="Times,serif" font-size="14.00" fill="#0571b0">IPTG</text>
</g>
<!-- IPTG->repression -->
<g id="edge13" class="edge"><title>IPTG->repression</title>
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<polyline fill="none" stroke="black" points="605.713,-57.6655 601.016,-55.9516 "/>
</g>
<!-- Doxycycline -->
<g id="node16" class="node"><title>Doxycycline</title>
<ellipse fill="#92c5de" stroke="#92c5de" cx="804" cy="-18" rx="55.7903" ry="18"/>
<text text-anchor="middle" x="804" y="-14.3" font-family="Times,serif" font-size="14.00" fill="#0571b0">Doxycycline</text>
</g>
<!-- Doxycycline->combination -->
<g id="edge17" class="edge"><title>Doxycycline->combination</title>
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