<tool id="gmt_music_pfam" name="gmt_music_pfam">
<description>
Add Pfam annotation to a MAF file
</description>
<command>
gmt music pfam --maf-file=$maf_file --output-file=$output_file
</command>
<inputs>
<param name="maf_file" format="maf" type="data" help="" />
</inputs>
<outputs>
<data name="output_file" format="pfam" label="" help="" />
</outputs>
<help>
**USAGE**
gmt music pfam --maf-file=? --output-file=?
**SYNOPSIS**
This command adds Pfam Domains to a column at the end of a MAF file.
**EXAMPLE:**
gmt music pfam --maf-file myMAF.tsv --output-file myMAF.tsv.pfam
**REQUIRED ARGUMENTS**
maf-file Text
List of mutations in MAF format
output-file Text
MAF file with Pfam domain column appended
**DESCRIPTION**
This tool takes a MAF file, determines the location of each variant therein, and then uses a
fast-lookup to retrieve all of the Pfam annotation domains that the variant crosses. A column is
appended to the end of the input MAF file called "Pfam_Annotation_Domains" where the results are
listed. "NA" is listed if no Pfam domains are found.
</help>
</tool>